use of prognostication for clinical decision making

Báo cáo y học: "Translational Medicine and Reliability of Single-Nucleotide Polymorphism Studies: Can We Believe in SNP Reports or Not"

Ngày tải lên : 25/10/2012, 10:51

... the following information from eligible trials: authors’ name, year of publication, country of origin, type of cancer, sample size, number of polymorphisms tested and results of the study Studies ... difference for any of the GST polymorphisms for at least one of the following outcome measures: overall survival or disease recurrence or response to treatment In the case of lack of a clear ... interpretation of potential misleading sources of literature-bias The existence of such type of bias in genetic association studies might lead to incorrect 497 conclusions about the usefulness of certain...

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How can we speak math?

Ngày tải lên : 26/10/2013, 19:15

... phone Not too tricky for the millions of people who use text messaging via phone, though.) • “Multimodal” assistance, for example for the task of correction (proofreading) of material that may ... a sine of x [implicit close] a sine x a sine of x all + y a sine of x + y all quantity over all + a sine of x + y quantity over close + sine of x all + cos of y all sine x + cos y sine of x + ... demonstrations of software which serve as intermediaries for the conversion of (hand)written material into typeset material More recently it has become plausible to actually make use of such programs...

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New English File - Can we make our own luck

Ngày tải lên : 01/11/2013, 16:20

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What is the neutral real interest rate, and how can we use it? doc

Ngày tải lên : 15/03/2014, 01:20

... conducts a survey of economic forecasters in New Zealand, asking them for their forecasts of, among other things, inflation They then compute the average forecast of all respondents We use the Consensus ... common understanding of the levels at which interest rates would be broadly stimulatory or contractionary A range of estimates of the NRR is therefore used to give an indication of where appropriate ... assumptions of the model by paying close attention to the sensibility of the model as a whole, and by treating the judgementally-adjusted model forecast as part of a range of possibilities of how...

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Central Bank Credit to the Government: What Can We Learn from International Practices? pdf

Ngày tải lên : 22/03/2014, 21:20

... one-eighth of the average budgeted revenues of each of Governments as defined in section 36 36 Meaning of annual budgeted revenue (1) For the purposes of section 35 the average budgeted revenues of the ... Explanation. For the purposes of this clause: (a) “repo” means an instrument for borrowing funds by selling securities of the Central 29 Government or a State Government or of such securities of a local ... government of any province, but such loans outstanding at any one time shall not, in the case of the Government of Canada, exceed one-third of the estimated revenue of the Government of Canada for its...

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Báo cáo khoa học: "How Much Can We Gain from Supervised Word Alignment" potx

Ngày tải lên : 23/03/2014, 16:20

... number of references used for scoring Had we used a test set with more references, the improvement in BLEU score would probably be higher An area for future work is to examine the impact of each ... Modeling of Extraction Sets for Machine Translation In Proceedings of the 48th Annual Meeting of the Association for Computational Linguistics, pages 1453– 1463 Related Work The study of the relation ... small magnitude of the gain using human alignment is not an artifact of small training Comparing giza-strong of Table with gizastrong of Table 2, we can see the difference in MT performance is about...

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báo cáo hóa học: " Can we derive an ''''exchange rate'''' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU) technique" doc

Ngày tải lên : 18/06/2014, 18:20

... change scores for individual patients Researchers responsible for the derivation of regression-based transformations might therefore wish to provide guidelines for end-users to ensure use consistent ... It is therefore possible that the evidence for generic to generic transformations may not be applicable in the case of condition-specific to generic transformations Transformation of descriptive ... validated for use in stroke [27,28] Moreover, our derivation of a Barthel to AQoL transformation for moderate to severe stroke widens the set of descriptive stroke-specific measures that can be transformed...

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báo cáo hóa học: " Can we make the basilic vein larger? maneuvers to facilitate ultrasound guided peripheral intravenous access: a prospective cross-sectional study" ppt

Ngày tải lên : 21/06/2014, 00:20

... below the level of the heart for more than 30 s prior to the application of a tourniquet, and holding the arm below the level of the Figure Ultrasound of basilic vein with measurement of anterior ... Journal of Emergency Medicine 2011, 4:53 http://www.intjem.com/content/4/1/53 heart for more than 30 s prior to inflation of a blood pressure cuff Measurements of basilic vein size were made before ... cross-sectional area of only 5.5% (1.46 mm2), which may not be a clinically significant difference for clinicians attempting USGPIV Application of a tourniquet with the arm below the level of the heart...

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Curcumin for monoclonal gammopathies what can we hope for, what should we fear

Ngày tải lên : 01/07/2014, 13:22

... has been used for centuries it is considered safe Indeed the results of some clinical Fig Structural formulas of the three main curcuminoids in turmeric trials indicated that even doses of up to ... possibility of side effects It is therefore mandatory to discuss reasons for potential concern [53] [54] [55] [55,56] [56] Curcumin for prevention of progression of MGUS and SMM, reasons for concern? ... of controlled clinical trials with validated clinical endpoints Only positive empiric evidence gathered in the course of such clinical studies will allow the validation of the vast quantity of...

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Can we do better than Agrobacterium ? pdf

Ngày tải lên : 02/07/2014, 11:21

... hàng ngày chuyển gen, chuyển gen chuyển gen Thêm hầu hết vector sử dụng CAMBIA (Center for the Application of Molecular Biology to International Agriculture), khỏi phải nói hứng thú có hội tham...

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Báo cáo sinh học : "What do we know about influenza and what can we do about it" ppsx

Ngày tải lên : 06/08/2014, 19:20

... operations of four WHO Collaborating Centers (London, Melbourne, Tokyo, Atlanta) and a host of National Laboratories A combination of RT- Journal of Biology 2009, PCR and rapid sequencing is used for ... range of phase to trials before it could be approved for human use As it is, the world has, with a current population of about 6.8 billion, never made more than about 400 million doses of trivalent ... material for such vaccines Although efforts are Journal of Biology 2009, 8:46 Volume 8, Article 46 Doherty and Turner 46.3 being made to develop cell-culture systems for producing large amounts of...

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Báo cáo lâm nghiệp: "Can we reconstruct deer browsing history and how? Lessons from Gaultheria shallon Pursh" pdf

Ngày tải lên : 08/08/2014, 00:21

... of several native animal species [17, 40] On the few deer-free islands, 40% of the shrub cover consists of salal [28], often in the form of continuous almost impenetrable thickets The cover of ... supplies about 10% of the total diet of black-tailed deer and it is of special importance in winter [18] Birds commonly eat salal berries, which can represent 45% of the diet of juveniles in August ... distribution of the height of the first leaves We compared mean age and mean stem height with a nested analysis of variance correcting the degree of freedom by Satterthwaite’s correction for unequal...

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Báo cáo y học: " MAPK signalling in rheumatoid joint destruction: can we unravel the puzzle? " pps

Ngày tải lên : 09/08/2014, 07:20

... different animal models of RA reflect distinct features of human disease Recent data on the involvement of MAPKs provide a basis for the development of novel therapeutic strategies for human RA Competing ... other recent data of Georg Schett’s group demonstrating that JNK1 is not required for destructive joint disease in the hTNFtg mouse model of RA [7] The data seem to contradict the aforementioned ... of data on JNK activation in human RA they more probably illustrate the complexity of human disease in comparison with the hTNFtg model, which focuses on only one, although central, pathway of...

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Báo cáo y học: "How can we reduce the risk of serious infection for patients with systemic lupus erythematosus" ppt

Ngày tải lên : 09/08/2014, 14:22

... processing of high affinity antigens (for example, foreign peptides) [6] The benefits of anti-malarials in patients with SLE go beyond preventing infection and include prevention of disease flares ... universal use of anti-malarial Page of (page number not for citation purposes) Ruiz-Irastorza G, Olivares N, Ruiz-Arruza I, Martinez-Berriotxoa A, Egurbide MV, Aguirre C: Predictors of major infections ... re-activation and infection prophylaxis for high risk patients Based on an estimated prevalence of 29% for serious infections among patients with SLE and the findings of Ruiz-Irastorza and colleagues,...

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báo cáo khoa học: "How can we improve guideline use? A conceptual framework of implementability" pps

Ngày tải lên : 10/08/2014, 10:23

... decision making, or behaviour of health professionals Studies were ineligible if they focused on guidelineinformed tools such as clinical pathways; guidelines for non-medical interventions; clinical ... support for different types of decision making (evidence-informed, experiential, shared, allocation/policy) by providing particular information and/or tools, and support for different types of decision- making ... to use guidelines and possibly actual use [30] For example, in a systematic review of 256 studies, 41 of them found that lack of comprehensible structure and local applicability were barriers of...

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báo cáo khoa học: " Prostate cancer genomics: can we distinguish between indolent and fatal disease using genetic markers?" docx

Ngày tải lên : 11/08/2014, 12:20

... thyroid adenoma associated isoform 1; TNRC6B, trinucleotide repeat containing 6B isoform bRisk alleles as defined from published data cited in the column a for both of these variants, the alleles ... The detection of inherited genetic markers capable of discriminating between indolent and fatal forms of prostate cancer holds promise to improve detection and clinical management of this disease ... classified as having a more aggressive form of the disease if they fulfill any of the following criteria: (1) disease spread outside of the prostate gland, or presence of cancer in the lymph nodes or...

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báo cáo khoa học: " Can we prevent drug related deaths by training opioid users to recognise and manage overdoses?" doc

Ngày tải lên : 11/08/2014, 18:20

... impact of programmes that target in treatment compared to out of treatment populations of heroin users In terms of formulation and type of prescription, the relatively bulky mechanism of a minijet ... systemic level For instance, there are issues of transportability of naloxone related to its formulation and also perceived stigma (the association of this drug with the 'active user of illicit substances' ... naloxone at the time of the witnessed overdose, of whom four reported that they kept it at home, two in their bag and for one case this information was missing The reasons for non -use were not related...

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Báo cáo khoa học: " Blood management in intensive care medicine: CRIT and ABC — what can we learn" docx

Ngày tải lên : 12/08/2014, 20:20

... information regarding the type of RBCs transfused and the effect of transfusion on outcome are available in the CRIT and ABC studies, so this remains an open question 90 In contrast, the age of ... the age of transfused RBCs and outcome was observed other than the risk of pneumonia increases with RBCs older than 28 days [9] The mechanism(s) by which potentially harmful effects of allogeneic ... Length of storage of transfused red cells and postoperative morbidity in patients undergoing coronary artery bypass graft surgery Transfusion 2000, 40: 101-109 Klein HG: Immunomodulatory aspects of...

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Báo cáo khoa học: " Understanding the lingering consequences of what we treat and what we do" potx

Ngày tải lên : 12/08/2014, 20:20

... effects of the associated ‘cytokine storm’ are strong candidates Yet many of the ICU controls may have similarly suffered profound inflammatory insults, and so some of the potential mechanisms for ... noise’ of preexisting conditions, and must specifically explore both the potential mechanisms of action for new decrements and the numerous interactions between different downstream outcomes For ... muscle mass during convalescence? How often does loss of lean muscle mass impair critical physical functions, such as getting in and out of bed or a chair? How often, and in whom, does change in...

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Báo cáo y học: "Percutaneous dilatation tracheostomy: which technique is the best for the critically ill patient, and how can we gather further scientific evidence" pptx

Ngày tải lên : 12/08/2014, 20:20

... classical technique of conic dilatation tracheostomy (introduction of a Crile’s forceps for blunt dissection of the pretracheal tissue), but it is unclear whether they controlled for the resulting ... dilemma in clinical research The study presented may provide highly important information for the institution where it was conducted, because the data have probably already been used for institutional ... techniques may be more appropriate in clinical practice from the viewpoint of the intensivist Because a sequential study design over a period of years was used, the data might have been subject...

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