... efficiency Another important point is the cohort of patients selected for such studies The main advantage of ACPA lies in their proven ability to predict the development of RA and their potential use as ... Linden and coworkers [17] – who showed that the rate of joint destruction in RA was not affected bythe presence or absence of IgM RF, but rather bythe presence or absence of ACPA – corroborate the ... compare the specificity and sensitivity of ACPA (and other) tests is the initiative ofthe European AutoCure consortium to generate a large depository of sera from patients with RA and other rheumatic...
... costs andthe expenses ofthe social and health services are increasing The report analyses the factors influencing theuseof social and health services bythe elderly On the basis ofthe analysis, ... is used to analyse by means of ordered logit models the impacts of age, dependency and other factors on probabilities to use home and community care for the elderly With these models andthe ... live in their own home The simulation program used in the next stage counts the number of users, intensity ofuseand costs of 11 domicile2 services We can satisfactorily match only three of the...
... were observed in the presence of ATP No change in the mobility ofthe Ure2p–Ssa1p complexes was detected in the presence of ATP The stoichiometry of Ure2p and Ssa1p within the 120 and 160 kDa cross-linked ... built from the X-ray structure ofthe C-terminal domain of Ure2p and integrates the finding that the N-terminal domain of Ure2p is flexible An enlargement ofthe region of Ure2p involved in the interaction ... list using the available softwares (gpmaw [30], xquest [31] and msx-3d [12]) with a mass tolerance of p.p.m We therefore used MALDITOF-TOF and ⁄ or nanoLC-Orbitrap tandem MS to further identify...
... and causes in theuseofthe past simple tense aspect of irregular verbs 34 2.2.3 Error and causes in pronunciation ofthe regular past 35 2.2.4 Error and causes in theuseof ... pronunciation of each of them and to help them improvement 2.2.4 Error and causes in theuseofthe simple past tense aspect for the past perfect tense aspect It can be seen from the result ofthe survey ... To find the major errors in theuseof past tense and aspects often made bythe eleventh- grade students at Thanh Ba High School in the academic year of 2012 – 2013 To find the causes ofthe errors...
... movement; • Was able to eliminate currency risk for the Germany supplier Bae CurrencyFutures versus CurrencyOptionsCurrencyFutures Obligation to buy/sell FC CurrencyOptions Right to buy/sell FC ... a currency put option When quantity of a FC cash flow is partially known and partially uncertain, use a forward to hedge the known portion and a currency option to hedge the maximum value ofthe ... value ofthe dollar changes, the sterling price of cocoa changes as well The objective of CS’s foreign exchange strategy is to eliminate thecurrency element in the decision to purchase the commodity,...
... information and education to the public and to users about the environmental consequences ofthe choice of particular activities and products, their useand ultimate disposal; (b) The development and ... subject-matter ofthe dispute 14 Unless the arbitral tribunal determines otherwise because ofthe particular circumstances ofthe case, the expenses ofthe tribunal, including the remuneration of its ... her usual place of residence in the territory of one of these parties, nor be employed by any of them, nor have dealt with the case in any other capacity If the president ofthe arbitral tribunal...
... surgery and long-term chemotherapy Bythe early 1980s, once more reinforced bythe results of Kodama et al,27 theuseof PSK as the immuno-component of chemoimmunotherapy consistently doubled the ... retrospective analysis of their success with combined radiation, chemotherapy, and immunotherapy in 133 cases.38 They concluded the addition of immunotherapy to the regimen using either PSK or OK-432 ... chemotherapy along with PSK immunotherapy The survival rate after recurrence was significantly extended bythe immunochemotherapy, in comparison to the other two groups The value of this type of...
... another and often separated the several fields on the same estate; but the cause of this was not so much the paucity of population as the character ofthe land andthe prevalent industry The sandy ... ship and cargo for each leg ofthe voyage, and for leakage of ten per cent ofthe rum and five per cent ofthe molasses, and after charging off the whole cost ofthe ship's outfit and one-third of ... company on the one hand andthe colonists and their legislatures on the other over the rating of colonial moneys andthe obstructions placed by law about the collection of debts; andthe colonists...
... bones ofthe skeleton are considered in three divisions: the _head_, the _trunk_, andthe _limbs_ THE HEAD THE BONES OFTHE SKULL ANDTHE FACE form a cavity for the protection ofthe brain andthe ... between the brain andthe rest ofthe body FIG [Illustration: _The Spine; the seven vertebræ ofthe neck, cervical; the twelve ofthe back, dorsal; the five ofthe loins, lumbar;_ a, _the sacrum, and_ ... are the power andthe weight is borne bythe ankle joint An illustration ofthe _third class_ is found in lifting the hand from the elbow The hand is the weight, the elbow the fulcrum, and the...
... isomers also showed the red shift and doubling of extinction coefficient on the addition of HCl [18] The dimethyl ester of biliverdin-IXa was synthesized by oxidation ofthe free acid of bilirubinIXa ... suggest that they may interact with the ‘roof’ and ‘floor’ of a hypothetical ‘verdin binding site’, with the nicotinamide ring forming part ofthe floor If the bound conformation is helical, there would ... synthesized by coupled oxidation of haem, producing the linear free acids Esterification ofthe Probing the verdin site of BVR-A and -B resulting free acids with BF3 ⁄ MeOH and separation of all...
... in the tiger prawn Penaeus monodon As there is a high degree of sequence similarity and structural conservation of these genes and gene products, confirmation ofthe true identity and function of ... level of MeMIH-B expression in the nerve cord was used as an indication ofthe RNAi effect between the treatment and control groups Statistical analysis of northern blots and western blots Northern ... drops of 20%, 71% and 23% ofthe overall MeVg1 transcript level were recorded (Fig 6A) Unlike in the hepatopancreas, the reduction of MeVg1 expression in ovaries of these female was small after the...
... statements, and memoranda have dealt with the status, function, andthe (il)legality oftheuseand possession of this category of ‘weapons of mass destruction’,1 and almost all of them agree ... to the spirit, letter and aims ofthe United Nations and, as such, a direct violation ofthe Charter ofthe United Nations; (b) Theuseof nuclear and thermo-nuclear weapons would exceed even the ... scope of war and cause indiscriminate suffering and destruction to mankind and civilization and, as such, is contrary to the rules of international law andthe laws of humanity; (c) Theuseof nuclear...
... Km and kcat for the hydrolysis ofthe substrates Mca-Ala and Mca-BK(1)8) bythe N-domain or the C-domain of human, mouse, or rat ACE were determined by blocking the activity ofthe C-domain by ... distance greater than A 1780 ofthe inhibitor, andthe backbone and Cb atoms ofthe inhibitor and those ofthe protein located at a distance ˚ smaller than A ofthe inhibitor, respectively No ... ACE species, the catalytic efficiency ofthe free enzyme corresponds to the sum ofthe catalytic efficiencies determined for the N-domain and C-domain in the presence of inhibitor These results...
... bythe Creative Research Group of National Science Foundation of China (Grant no 50721003), the Foundation ofthe Ministry of Education of China for Returned Scholars (Grant no 2005383) andthe ... about 3:2:2, which corresponds well to the standard SiC and SiO2 The small quantity of oxygen may come from the resident oxide layer The IR spectrum ofthe as-synthesized SiC nanowire samples (Fig ... from the bulk [21], film [22] and nanowire [23] of SiC, the emission peak for b-SiC nanowires is obviously shifted to the blue The emergence ofthe peak with a blueshift is due to the existence of...
... migration and resolution mediated bythe E coli RuvABC resolvasome complex requires the binding of RuvA to one face ofthe junction and RuvC to the other [8,9] Complexes formed bythe loading of both ... BIAEVALUATION software To remove the effects ofthe bulk refractive index change at the beginning and end of injections (which occur as a result of a difference in the composition ofthe running buffer and ... importance of this structure is reflected in the high conservation ofthe sequences forming the pin in the majority of bacteria with the exception of two Mycoplasma species and one of Ureaplasma In the...
... the patient; likewise, the patient may not be able to verify that a physician is on the other end ofthe communication For that reason, the standards of medical care not change by virtue ofthe ... How these ethical standards relate to the proper useof social media by physicians is explored further in the next section Section Four Guidelines for the Appropriate Useof Social Media and ... efforts ofthe members ofthe Special Committee on Ethics and Professionalism who provided input and direction for this project Model Guidelines for the Appropriate Useof Social Media and Social...
... weighting ofthe quality ofthe evidence andthe grade ofthe recommendation [3] (Table 1) A detailed description ofthe methods, background, and evidence summaries that support each ofthe recommendations ... living in the United States, with reasonable access to healthcare The history, presentation, and examination ofthe child are the major determinants ofthe severity ofthe illness andthe appropriate ... beyond the endotracheal tube tip The inner catheter is then extended cm further andthe protective plug expelled, allowing the brush to be advanced another 1-2 cm, and then retracted into the sheath...