... skewing of X chromosome inactivation patterns is transmitted to offspring in humans. J Clin Invest. 20 08; 1 18: 333-341. 20. Busque L, Mio R, Mattioli J, et al. Nonrandom X- inactivation patterns in ... 57/43 46/54 58/ 42 275/ 281 47/53 GC31 ϩϩ 71/29 68/ 32 68/ 32 72/ 28 272/272 - GC32 ϩ 56/44 63/37 2 78/ 284 20 /80 GC33 ϩ 60/40 64/36 275/ 281 40/60 GC34 ϩϩ 56/44 62/ 38 60/40 64/36 275/ 284 90/10 GC35 ... have not observed clonal X-chromosome allelic expression in studies involving more than 200 healthy women, indicating this is a rare phenomenon in the general population. 10 However, we did not...
Ngày tải lên: 05/03/2014, 21:20
... including all the mutations in the putative CD81 binding region 1 (Y474A, D 481 A, R 483 A, Y 485 A, W 487 A, H 488 A, Y 489 A, and R492A) sug- gesting that this region is not directly involved in binding CD81 ... WT VSV-G EnvA Y474A D 481 A R 483 A Y 485 A W 487 A H 488 A Y 489 A R492A Y527A W529A D533A D535A W549A F550A Y613A R614A L615A W616A H617A Y618A RLU (log) CD81 binding region 1 CD81 binding r egion 2 CD81 binding r egion ... WT VSV-G EnvA Y474A D 481 A R 483 A Y 485 A W 487 A H 488 A Y 489 A R492A Y527A W529A D533A D535A W549A F550A Y613A R614A L615A W616A H617A Y618A RLU (log) CD81 binding r egion 1 CD81 binding r egion 2 CD81 binding region...
Ngày tải lên: 20/06/2014, 01:20
usb mass storage designing and programming devices and embedded hosts
... numeric data. Mass- storage devices typically store information in files. A file system defines how the files are organized in the storage media. In Windows computers, mass- storage devices appear ... programming a USB mass- storage device or embedded USB host involves a variety of interfaces, protocols, and structures. Every USB mass- storage device must support two interfaces: ã A USB device interface ... 185 Selecting a File System 185 Cluster Sizes 185 A Hardware Solution 186 The File Allocation Table 188 The First Two Entries 188 Data Clusters 188 Accessing the FAT 190 Volume Information 190 File Information...
Ngày tải lên: 06/07/2014, 15:37
how come your brand is not working hard enough
... put into advertising effort. So what if you don’t advertise? No brand? Saddest of all the misunderstandings is that which dismisses branding as unworkable in anything but a FMCG (fast- moving ... impulses behind the writing of this book. Good branding takes a lot of good thinking. This is not to say that brands should be managed by intellectuals, or that we should allow the jargon- spouting folk ... others. This isn’t just a question of money, it is about consistency and good use of the past. 18 í Defining the brand Finding and securing your brands level: ã brand activity ã customer interaction ...
Ngày tải lên: 01/08/2014, 17:24
Chapter 33: Advanced Object-Oriented Concepts s sThe object table itself is not mentioned in the pps
... from the input variable in the main method) is then processed, and a variable named areacircle is calculated and returned to main. In main, that value is then printed: double result=area(input); System.out.println(result); Chapter ... function is defined later in the class, in the section beginning // Utility function to read a line from standard input static String readEntry (String prompt) Once the connection data has been input, ... handling blocks are unchanged from the prior example. The change is in the main method: int input=Integer.parseInt(args[0]); while (input < 7) { double result=area(input); System.out.println(result); input++; } 642 Part...
Ngày tải lên: 07/08/2014, 14:20
Báo cáo y học: "Differentiation of naive CD4+ T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients" pps
... (Print ISSN 14 78- 6354; Online ISSN 14 78- 6362). This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice ... WB: Role of interleukin-4 and inter- leukin-10 in murine collagen-induced arthritis. Protective effect of interleukin-4 and interleukin-10 treatment on carti- lage destruction. Arthritis Rheum 1997, ... production of proinflammatory cytokines and immunoglobulins by interleukin-4 in an ex vivo model of rheumatoid synovitis. Arthritis Rheum 1992, 35 :87 4- 88 3. 16. Isomaki P, Luukkainen R, Toivanen...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo khoa hoc:" Aortic distensibility measured by pulse-wave velocity is not modified in patients with Chagas'''' disease" pot
Ngày tải lên: 11/08/2014, 08:20
Báo cáo y học: " HIV-1 Rev oligomerization is not obligatory in the presence of an extra basic domain" doc
Ngày tải lên: 13/08/2014, 09:21
Báo cáo y học: "RNA interference is not involved in natural antisense mediated regulation of gene expression in mammals" docx
Ngày tải lên: 14/08/2014, 16:21
Báo cáo Y học: Regulation of RAS in human platelets Evidence that activation of RAS is not sufficient to lead to ERK1-2 phosphorylation pot
... secretion induced by thrombin. Interestingly, although inhibitors of PtdIns3K abolished this potentiation, the inhibitor of MEK had no or only a weak effect, suggesting that the MEK– ERK cascade is not ... phospholipase A2 is phosphorylated in collagen- and thrombin- stimulated human platelets independent of protein kinase C and mitogen-activated protein kinase. J. Biol. Chem. 270, 2 588 5–2 589 2. 8. Pasquet, ... activity in response to thrombin and convulxin. This is consistent with the observation that TPO, which is unable to induce activation of PKC, does not stimulate activation of ERK in platelets. This...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo khoa học: Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart potx
... saturation of the two isoenzymes of OGDH with 2-oxoglutarate. Discussion Identification of novel OGDH isoform and its implication in brain metabolism Distinguishing proteins with highly similar ... protein–protein interactions of the 2-oxo acid dehydrogenases [ 28, 45– 48] . Hence, isoenzyme-specific protein–protein interactions may also lead to the over-representation of E1o over E2o in brain OGDHC ... 67 13 088 E-mail: georg.reiser@med.ovgu.de (Received 17 April 20 08, revised 5 July 20 08, accepted 8 August 20 08) doi:10.1111/j.1742-46 58. 20 08. 06632.x 2-Oxoglutarate dehydrogenase (OGDH) is the...
Ngày tải lên: 23/03/2014, 06:20
Hướng dẫn khắc phục lỗi “username is not in the sudoers file...” trong Ubuntu doc
... việc gì nữa, và thay vào đó hệ thống sẽ hiển thị thông báo lỗi như sau: damien is not in the sudoers file. This incident will be reported trong đó damien là tên tài khoản đang sử dụng. Trong ... admin damien Thoát khỏi Command Prompt và quay trở lại chế độ khởi động bình thường, và vấn đề trên đã được giải quyết. Chúc các bạn thành công! Hướng dẫn khắc phục lỗi “username is not in ... ALL # Members of the admin group may gain root privileges %admin ALL=(ALL) ALL # Allow members of group sudo to execute any command %sudo ALL=(ALL:ALL) ALL #includedir /etc/sudoers.d...
Ngày tải lên: 30/03/2014, 00:20
Báo cáo khoa học: Cyclosporin A-induced oxidative stress is not the consequence of an increase in mitochondrial membrane potential doc
... NIM811 had no effect. None of the three substances induced a significant increase in JC-1 fluorescence in GLC4 cells. Despite this, cyclosporin A, NIM811 and PSC833 induced a 1.5-fold increase in DCF ... control substance in this context, because it is an inhibitor of P-glycoprotein rather than MPTP, and is devoid of calcineurin-inhibiting properties [23]. We hypothesized that an increase in steady-state DW m underlies ... neither NIM811 nor PSC833 inhibit calcineurin. It is further- more also unlikely that the P-glycoprotein-inhibiting properties of CsA play a role, because CsA, NIM811 and PSC833 all increased...
Ngày tải lên: 30/03/2014, 08:20
Báo cáo khoa học: "Optimization in Coreference Resolution Is Not Needed: A Nearly-Optimal Algorithm with Intensional Constraints" ppt
... labeling via integer linear program- ming inference. In Proc. of the COLING. S. Riedel and J. Clarke. 2006. Incremental integer linear programming for non-projective dependency parsing. In Proc. ... (even from the beginning of the text) with every other succeeding markable? This is linguistically im- plausible. Pronouns are acting as a kind of local variables. A ’he’ at the beginning of a text ... coherent discourses. In Proc. of the ACL. A. Bagga and B. Baldwin. 19 98. Algorithms for scor- ing coreference chains. In Proceedings of the Lin- guistic Coreference Workshop at The First Interna- tional...
Ngày tải lên: 31/03/2014, 20:20
Báo cáo hóa học: " Human cytomegalovirus UL27 is not required for viral replication in human tissue implanted in SCID mice" ppt
... [2], and this recombinant virus contains a deletion that eliminates the amino terminal 80 % of the open reading frame starting just upstream of the start codon (coordinates 33021–34565 in X17403). Two ... mg/kg), xylazine (15 mg/kg) and the topical anesthetic propa- racaine-HCL (0.5%) was instilled in the eyes. A winged infusion needle containing mechanically dissociated human fetal retinal tissue was ... clear pattern emerged. This is consistent with previous reports describing the limited replication of this strain in this sys- tem. It is unclear whether the apparent differences in replica- tion of...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " The synergistic effect of IFN-α and IFN-γ against HSV-2 replication in Vero cells is not interfered by the plant antiviral 1-cinnamoyl-3, 11-dihydroxymeliacarpin" pptx
... viral infection depends on the integrity of this network of cytokines, which is tightly regulated [19]. This in vivo situation led us to query whether the administra- tion of meliacine to HSV-2 infected ... [25]. Considering this background the current investigation was undertaken to determine if IFN combination inhib- ited in a synergistic manner HSV-2 replication in Vero cells, and if so to determine if ... meliacine, a plant antiviral, ameliorate the severity of the herpetic infection in female mice infected intravaginally with HSV-2, we wanted to investigate whether the administration of meliacine...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" HIV prevention is not enough: child survival in the context of prevention of mother to child HIV transmission" potx
... intrapartum transmission to 8% . Assuming breastfeeding transmission risk is unaffected, an addi- tional 14% acquire infection postnatally, bringing the total transmission rate to 22%. In this scenario, ... [8] . This is a win-win interven- tion that treats the mother while preventing transmission. It is important to understand why rational integration of adult HIV treatment programmes and PMTCT is ... And this dark cloud is pro- vided by the shifts in infant feeding practices that have occurred in many places, inspired by the fear of HIV trans- mission. In many places, HIV-infected women in commu- nities...
Ngày tải lên: 20/06/2014, 08:20
Báo cáo lâm nghiệp: " Partitioning of remobilised N in young beech (Fagus sylvatica L.) is not affected by elevated [CO2]" ppsx
... 285 Ann. For. Sci. 62 (2005) 285 288 â INRA, EDP Sciences, 2005 DOI: 10.1051/forest:2005021 Note Partitioning of remobilised N in young beech (Fagus sylvatica L.) is not affected ... tends to decrease [2], indicating that store formation is not increased under elevated [CO 2 ]. It has been shown, that N stores formation in beech (Fagus sylvatica L.) was not increased under elevated ... functioning in an enriched CO 2 atmosphere, New Phytol. 139 (19 98) 395–436. [14] Tagliavini M., Millard P., Quartieri M., Marangoni B., Timing of nitrogen uptake affects winter storage and spring...
Ngày tải lên: 08/08/2014, 00:21
Báo cáo y học: "Synovial expression of IL-15 in rheumatoid arthritis is not influenced by blockade of tumour necrosis factor" docx
Ngày tải lên: 09/08/2014, 07:20
Báo cáo khoa học: "bcl-2 expression is not associated with survival in metastatic cutaneous melanoma: A historical cohort study" pptx
Ngày tải lên: 09/08/2014, 07:21