understanding the extreme by way of the sublime

... moment, the fundamental resources and systems needed for the care of the critically ill patient are (a) staff, (b) the ways that they interact with each other, and (c) the non-human elements of systems ... significant potential to elucidate these individual influences and their interactions Better understanding of these human and non-human elements of the system of care of the critically ill patient is ... the study of the function of people and teams at a detailed level is somewhat location-specific, and studies need to be scrutinised for transferable lessons Many of the themes identified in the...

Ngày tải lên: 13/08/2014, 16:20

... we used the theory of the metabolic control analysis [24] by applying an elasticity analysis This consists of the experimental determination of the sensitivity of segments of the pathway towards ... [33,35,36] or by actually determining the effect of the branching pathways on the main flux and on the concentration of the connecting metabolite [23] To determine the elasticity coefficients of the consumer ... derived from the elasticity coefficients are also shown These data clearly established that the main control of the glycolytic flux in AS-30D cells resides in the upstream part of the pathway The experiments...

Ngày tải lên: 30/03/2014, 11:20

... call this the conversion rate of your website Essentially the conversion rate is the percentage of visitors you get on your site that fill out your form and become a lead There are a LOT of different ... Each of these online insurance marketing methods will charge a different amount for each of the clicks that you get to your website And all of them work on an auction basis, ... probably have a ton of other questions about how all of this works That's why I put together a free video that will take care of those questions for you All you have to is click the button below...

Ngày tải lên: 27/06/2014, 23:20

... evaluations of their caring experiences (see Figure 1) We have also taken the liberty of abridging some of the more detailed narratives into poems, which summarise the content of their accounts of their ... to their circumstances are often a by- product of their negotiation between these expectations Nevertheless, the negotiation of meanings that these children actively engage in facilitates their ... affected by HIV/AIDS In the absence of working adults in their households, many of the children were responsible for the generation of food and income to sustain their household Alongside these...

Ngày tải lên: 11/08/2014, 14:21

... and dimerization of the receptor Indeed, dimerization is essential for the activity of PPARs, as it is for most of the other members of the nuclear hormone receptor superfamily They heterodimerize ... [32,33] A number of studies point to the importance of the sequences flanking the PPREs for maintaining the optimal conformation of the PPAR-RXR heterodimers on the PPREs [34,35] These flanking ... activation of both p38 and ERK has been shown to lead to the release of TNFα and IL-6 by macrophages and other cell types [99,100] Therefore, one of the functions of MAP kinase signaling pathway may...

Ngày tải lên: 13/08/2014, 13:20

... consumption of the substrate deposits and the dysfunction or failure of the specialized epithelia of the body could also represent an accelerated process of epithelial dedifferentiation [12,14,32] The ... (Figure 1) Nevertheless, angiogenesis could have other functions in the phases prior of the inflammatory response The earliness of endothelial proliferation, as well as the ability of these cells ... aggravate the intensity of the inflammatory response [18] It is possible that another organ, like the endothelium, associated with the progressive reduction of the anti-oxidant capacity of the liver...

Ngày tải lên: 13/08/2014, 16:21

Ngày tải lên: 08/08/2012, 17:20

... [15] The synthesis of the tetrazine dicarbonic acid derivate was performed as described by [15] The synthesis procedure of the corresponding dansyl derivative was carried out according to the ... chemical reaction by the solid phase peptide synthesis (Figure 4) Ligation of the pentamer I with the tetrazine-dicarboxylate 6: One µmol of the pentamer I (Figure 3) and 5.5 µmol of the tetrazine ... ligation of the tetrazine derivatized polyamide pentamers The scheme describes the polyamide pentamer molecule after the complete ligation by the DARinv (shortened to the reaction site) Details of the...

Ngày tải lên: 25/10/2012, 11:00

... may be their countenance was not more than necessary The purity of his style, the delicacy of his turns, and the justness of his characters, were all of them beauties which the greater part of his ... in the formation of his characters from the observations of Theophrastus, of whom he was a disciple; and Theophrastus, it is known, was not only the disciple, but the immediate successor of Aristotle, ... wonder not they were weary of you; last night was one of their cabal-nights: they have 'em three times a week and meet by turns at one another's apartments, where they come together like the coroner's...

Ngày tải lên: 06/11/2012, 15:30

Ngày tải lên: 20/12/2013, 18:15

... small way to the technical proficiency and competencies of IT professionals at IMS However, there is a danger that these achievements could be overshadowed by overselling the capabilities of the ... use of the decision tree in consultation mode at the distributed regional interfaces is therefore excluded, in the [initial version of the application] If, in the longer term, it emerges that there ... ultimately, themselves redundant In reaction to the probability of industrial unrest, Coillte dispensed with the services of IMS—Sean Breen, IMS’s CEO described the situation thus: The first phase of the...

Ngày tải lên: 20/12/2013, 19:15

... with an understanding of each of the seven layers, including their functions and their relationships to each other This will provide you with an overview of the network process, which can then act ... Protocols, or rules, can their work in either hardware or software or, as with most protocol stacks, in a combination of the two The nature of these stacks is that the lower layers their work in hardware ... as a framework for understanding the details of computer networking Since the discussion of networking often includes talk of “extra layers”, this paper will address these unofficial layers as...

Ngày tải lên: 24/01/2014, 09:20

... adjusted at any point Either the beginning or the end of the line can be attached to an already existing object which can be broken at the intersection point with the double line The “DOUBLE LINE” ... This allows the user to trace a continuous double line by using straight line segments and arcs The line’s ends can be closed and the angles can be adjusted automatically The width of the double ... has a bar for typing commands and a series of icons arranged around the drawing area which facilitate and speed up the use of the various functions There are obviously pull-down menus which,...

Ngày tải lên: 25/01/2014, 19:20

... to the Chairman of the Board of Health, under date of the 20th June, 1922, from the Council of the New Zealand Branch of the British Medical Association The Board of Health duly considered the ... the individuals infected, but upon the health and well-being of the community as a whole This ignorance of the nature of the problem and of the grave issues involved naturally stands in the way ... of the evil being grappled with effectually Furthermore, the policy of reticence which has prevailed in the past, while it has led to the omission of proper instruction of the young, either by...

Ngày tải lên: 17/02/2014, 14:20

... Titration of CyaY with Fe2+ and Fe3+ Addition of Fe2+ induced the displacement of several resonances in the [1H,15N]-HSQC NMR spectrum of CyaY, but the most striking consequence of the addition was the ... disappearance of specific resonances without the concomitant appearance of other signals in other parts of the spectrum This result could be a consequence of the paramagnetic properties of Fe(II), ... induce a line ˚ broadening of 1–100 Hz in nuclei located within A of the binding site, depending on the molecular mass of the protein and the strength of the magnetic field The only exceptions are...

Ngày tải lên: 18/02/2014, 16:20

... as a consequence of the mutagenic replacements Effects of the His120Asn and His145Asn mutations on the affinity of metal binding to arginase II To further examine the effects of the His120fiAsn and ... analysis of the effect was not performed, the inhibition by 20 mm agmatine was eliminated by saturation with l-arginine, indicating the competitive character of the inhibition produced by the substrate ... both the lack of arginase activity as well as the resistance of the Asn149Asp mutant to inhibition by l-arginine, would be explained by electrostatic repulsion between the a-carboxyl group of the...

Ngày tải lên: 20/02/2014, 02:21

... name of an intent class For example, the IH of the query “alice in wonderland 2010 cast” is “cast”, which is an attribute name of Movie By issuing the query, the user intends to find out the values ... goal of this work is to identify the semantic labels of IMs, i.e., the attribute names they implicitly refer to We use Ac to denote the set of IM semantic labels for the intent class c Other ... models for semantic understanding of noun phrase queries Assuming that the intent class c ∈ C of a query is known, we cast the problem of extracting the semantic structure of the query into a joint...

Ngày tải lên: 20/02/2014, 04:20

... task, but with the provision of c o n t e x t s w h i c h are f e l i c i t o u s w i t h one or other of the two versions of their examples the with the to NP) In the case of the n o n - m i ... one of them but not of the other "MINIMAL INFERENCING" A policeman was questioning two women He had his d Q u b t $ a b o u t one of t h e m but not a b o u t the other RELATIVE CLAUSE TARGET The ... a u s e of the i n c r e a s e d n u m b e r of t h e s e v i o l a t i o n s It w o u l d appear, then, that much of the evidence cited in the literature concerning the resolution of local...

Ngày tải lên: 22/02/2014, 09:20

... with their personalised set of commitments For those closest to the labour market this loss of benefit for the period of their non-compliance may be permanent For others, some or all of their ... The previous chapters outlined the kind of approach we are considering to address the failings of the current benefits system These ideas are underpinned by the key aims outlined in chapter of ... alongside consideration of reform of the structure of the system Subject to the outcome of this consultation, we hope to bring forward legislation early in the New Year to reform the benefits and Tax...

Ngày tải lên: 06/03/2014, 08:20