... significant clinical benefits like disease stability in 80% of patients after 2–3 doses of vaccine The mean survival rate was 13 months for melanoma patients and months for renal cell carcinoma patients ... very small prostate tumors This, in association with radical prostatectomy and radiation therapies, has contributed to increasing the curative indexes [2] After several years of primary therapy, ... metaanalyses of ten clinical trials in melanoma patients (167 patients total) These data support mature DCs as the best choice for conducting clinical trials We prepared DC vaccines using allogeneic...
... Modulation of metal availability for treating AD P J Crouch et al research attention as potential therapeutic targets Plaques and NFTs, however, cannot be regarded as ‘upstream’ causative factors ... down-regulated by decreased availability of intracellular Cu [83] and up-regulated by increased availability of Cu [84] Collectively, these data present a strong case forthe native role of APP ⁄ Ab ... Furthermore, an increase in extracellular metals can catalyse Ab oligomerization and aggregation, and the amyloid plaques that subsequently form may then exacerbate intracellular metal deficiency...
... The mainstay of surgical therapy in primary or metastatic disease is to achieve a complete resection with negative margins [7] Conventional chemotherapy and radiation therapy may have minor adjunctive ... Kubota K, Makuuchi M, Kusaka K, Kobayashi T, Miki K, Hasegawa K, Harihara Y, Takayama T: Measurement of liver volume and hepatic functional reserve as a guide to decision-making in resectional ... colorectal liver metastases Am J Surg 2003, 185:221-229 Kawasaki S, Makuuchi M, Kakazu T, Miyagawa S, Takayama T, Kosuge T, Sugihara K, Moriya Y: Resection for multiple metastatic liver tumors after...
... slightly lower mean rates of carbon uptake before and during the first day of cold acclimation After days of cold exposure, the mean rate of carbon uptake was significantly lower for C24 than for Rsch ... T, Sawodny O, Ederer M & Heyer AG (2010) Mathematical modelling ofthe central carbohydrate metabolism in Arabidopsis thaliana reveals a substantial regulatory influence of vacuolar invertase ... Experimental procedures, the rate of assimilate export from photosynthetically active source organs to consuming sink organs or metabolic pathways other than carbohydrate pathways was calculated as the...
... Hyderabad, India, January William A Woods 1970 Transition network grammars for natural language analysis Communications ofthe ACM, 13(10):591–606, October Gerald Gazdar 1988 Applicability of indexed ... Memory-inductive categorial grammar: An approach to gap resolution in analytic-language translation In Proceedings ofThe Third International Joint Conference on Natural Language Processing, volume 1, pages ... derivation, we can then replace the decomposition rule ofthe canonical CCG with the gap resolution process of MICG Fillers and gaps are associated in the coordination and serialization by the gap-resolution...
... Critical Care Vol 10 No Garnacho-Montero and Amaya-Villar Van de Woude et al [1] propose a clinical algorithm based on the criteria defined by an international conference on the diagnosis of aspergillosis ... of bronchoalveolar lavage was not positive [13], a criterion not universally accepted Moreover, a high resolution CT scan is nowadays mandatory and a normal portable chest X-ray may lead to an ... Garnacho-Montero J, Amaya-Villar R, Ortiz-Leyba C, León C, Álvarez-Lerma F, Nolla-Salas J, Iruretagoyena JR, Barcenilla F: Isolation of Aspergillus spp from the respiratory tract in critically...
... de-innervation ofthe joint and removal ofthe entire end-plate receptors that adhere to the bone and capsular tissue Limitations ofthe current study include a lack of comparison group and lack of blinding ... low back pain Pain Physician 1999;2:59-64 Manchikanti L, Pampati V, Fellows B, et al The diagnostic validity and therapeutic value of lumbar facet joint nerve blocks with or without adjuvant agents ... men; mean age 64, range 22-89) were included Length of follow-up was at least years with a maximum of years Location of facet pain was cervical in 45, thoracic in 15, and lumbar in 114 patients...
... Nazarpour, S Sanei, and J A Chambers, Anovel semiblind signal extraction approach incorporating PARAFAC forthe removal ofthe removal of eye-blink artifact from EEGs,” in Proceedings ofthe ... signature of factor The spatial signature of factor (c) (d) Figure 6: The extracted factors by using PARAFAC; (a) and (b) illustrate, respectively, the spectral and temporal signatures ofthe extracted ... clean signals coming from nonfrontal areas 3.3 Performance evaluations In order to provide a quantitative measure of performance forthe proposed artifact removal method, the CC values of the...
... codon)-3’ and the “second round PCR” (one -for- all) primer set: One -for- all-forward: 5’-GGGGACAAGTTTGTACAAAAAAGCAGGCT-3’ and One -for- all-reverse: 5’-GGGGACCACTTTGTACAAGAAAGCTGGGTC-3’ PCR products containing ... in large scale as described by Soutscheck et al [12], rearranged in line assay format and validated with a number of pre-characterized serum samples These validation data confirmed the seroreactivity ... analysis, expression and purification of proteins in small format, ELISAs assays, data analysis and Page of wrote the manuscript KIP carried out large scale protein purification, microarray screen, line...
... PE38) has undergone several early-phase clinical trials forthetreatmentof B cell malignancies [35–37] These trials have validated the use of CD22 as a target and highlighted several potential ... ofthe majority of domain Ia (D1–250) and a portion of domain Ib (D365–380) from native PE Several RITs incorporating a 38 kDa fragment of PE are in preclinical evaluation or have already reached ... of PE and its intoxication pathway have fueled the translation of basic research into clinical therapies that have the opportunity to make a large positive impact on human health High expectations...
... is the name ofthe "class of endings" associated with every lemma A class of endings is the set of all the endings related to a given class of words For example, each ofthe regular verbs ofthe ... approach to the problem is to store in a data base a list of all the declined forms for every lemma ofthe language, as well as their morphologic, syntactic and semantic characteristics The size of ... structured as tables ofa relational data base l the morphologic and semantic characteristics ofthe word, but not its syntactic cathegory: for example, the easa (house) can be altered in casina (little...
... in the analysis In clinical practice, patients have different characteristics which will demand a reasoned approach to the choice oftreatment at any one time Thus it cannot be assumed that additional ... with adjunctive therapy or the actual exercise dosage is the critical factor is unclear The optimal length oftreatment and the number oftreatment episodes could be useful information forthe marketing ... information, both for consumers and forthe calculation ofthe economic benefits of physical therapy particularly when compared with alternative treatments Question 2: What is the evidence for...
... purposed the assessment ofthe migration capacity ofthe cells At the moment there is no consensus in establishing acceptance criteria forthe migration capacity of BM-MNC in cardiac regeneration ... H, Murohara T, Ikeda U, Shintani S, Masaki H, Amano K, Kishimoto Y, Yoshimoto K, Akashi H, Shimada K, Iwasaka T, Imaizumi T: Therapeutic angiogenesis for patients with limb ischaemia by autologous ... and coordination All the authors read and approved the final manuscript References Regulation (EC) No 1394/2007 ofthe European Parliament and ofthe Council of 13 November 2007 on advanced therapy...
... type diabetes subjects Immunogenetics 2010, 62:101-107 36 Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, et al: Genetic association ... Health Center, 1650 Cedar Avenue, Montreal, H3G 1A4 , Qc, Canada Full list of author information is available at the end ofthe article thymic and peripheral CD4+ T cells in humans and mice, and ... Cobbold S, Alyanakian MA, Gouarin C, Barriot S, Garcia C, Waldmann H, Bach JF, Chatenoud L: Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic...
... parallel 1.8 mm Kirschner wires from the tip ofthe olecranon and a 18 gauge wire in a figure -of eight fashion Major intraoperative goal was the perforation ofthe ulnar Mayo Classification for ... Visual Analogue Scale (VAS) patient satisfaction score (b) the intramedullary pin The above hypothesis wasn't confirmed by Paremain et al [22] as the results of their biomechanical study indicated ... olecranon fracture Mayo Type IIA fracture ofthe left olecranon after a fall in a 52-year-old woman (A) Lateral (B) and anteroposterior radiographs (C) at years postoperatively showed signs of...
... is a chance of intra-articular pin placement, causing septic arthritis and a risk of damaging the growth plate An external fixator is also used forthetreatmentof paediatric supracondylar fractures ... this article as: Lam et al.: The use of tibial Less Invasive Stabilization System (LISS) plate [AO-ASIF] forthetreatmentof paediatric supracondylar fracture of femur: a case report Journal of ... the site, the pattern ofthe fracture and its associated injury When treating the displaced supracondylar fracture, the traditional method of traction may fail due to the unbalanced pull of the...
... Page of 100 points indicating a normal foot This includes a maximum score of 30 points for amount of pain; of 20 points each for level of activity and patient satisfaction; and of 10 points each ... permits and consists of gentle manipulation ofthe foot and the serial application of long leg plaster casts at weekly interval without the use of anesthesia, as described by Ponseti [4] In all patients, ... each for motion ofthe ankle and foot, position ofthe heel during stance, and gait For Satisfaction and Function category, data has been recorded from the patients’ parents considering patient as...
... Page of 100 points indicating a normal foot This includes a maximum score of 30 points for amount of pain; of 20 points each for level of activity and patient satisfaction; and of 10 points each ... permits and consists of gentle manipulation ofthe foot and the serial application of long leg plaster casts at weekly interval without the use of anesthesia, as described by Ponseti [4] In all patients, ... each for motion ofthe ankle and foot, position ofthe heel during stance, and gait For Satisfaction and Function category, data has been recorded from the patients’ parents considering patient as...
... on a Waters Q-TOF Premier & Aquity UPLC spectrometer Surface area ofthe catalyst before and after use in the reaction was measured using surface area & pore size analyzer (NOVA 1000e, Quanta ... and novel method forthe preparation of oximes The methodology also offers chemical, economical, and environmental advantages On the other hand, Bi2O3 is remarkably easier to use, nonhazardous, ... [6], amines [7], and synthesis of azaheterocycles [8] are some ofthe synthetic applications of oximes They are also useful for selective a- activation [9] and are extensively used as intermediates...
... study Additional studies appear warranted forthe use of Apatone as a co–adjuvant, or for emerging salvage chemotherapy in thetreatmentof late stage prostate cancer Acknowledgements This research ... fit analysis was used to measure and compare PSA values before, during and after therapy.12 Prostate cancer patients who had failed standard therapy were enrolled at William Beaumont, Royal Oak, ... of prior chemotherapy regimens was two Table Patient Characteristics N = 17 Age: median (range) AUA Symptom Score: median (range) Race: Caucasian African American Prior therapies (1 or more treatments):...