two photon recording of action potentials in mammalian nerve terminals
Báo cáo y học: " Propagated repolarization of simulated action potentials in cardiac muscle and smooth muscle" pptx
... applied to the inside of the last cell (A5) of the chain when the APs of all cells were in their plateau phase The intensity and duration of the IS2 pulses were varied over a wide range in order to ... in a retrograde direction down the 5-cell chain B: 1,000 gj-channels inserted (Rgj of 10 MΩ) Again, the rising phase of the APs of the cells were nearly superimposed C: 100 gj-channels (Rgj of ... several VM values and inserted into the GTABLE function Experiments were done with a single chain of cells or cells There were no gap junctions between the cells of the chain under initial conditions...
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Tài liệu Báo cáo khoa học: Key role of the loop connecting the two beta strands of mussel defensin in its antimicrobial activity docx
... is not possible to infer whether the key role of the b-hairpin loop of MGD1 (loop 3) in antimicrobial activity of MGD1 is of general value in the mechanism of action of defensins However, our results ... obtained by other groups who also point to the role of the connecting loop of the b-hairpin of defensins A combination of mutational analysis [35] and structural analysis of the plant defensin ... identified two subsites on this molecule comprising Ôresidues in the protruding domain consisting of the type VI b-turn and the first part of b-strand 3Õ (i.e the b-hairpin loop and part of the adjoining...
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Research report, "Some convergence theorems for arrays of two average index of random elements in Banach spaces with integrable conditions on" pptx
... Notes in Mathematic; Springer-Verlag: Berlin, 672, 1978 in Linear Space, [7] L V Thanh, Mean convergence theorems and weak laws of large numbers for double arrays of random variables, Journal of ... sums of Banach- space-valued random elements under some conditions of uniform integrability, of Mathematical Sciences, 138 (1), 2006, 5450-5459 [3] J Hoffmann-Jrgensen and G Pisier, The law of ... the same one in each appearance III Main results Theorem Let r
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Báo cáo y học: "Comparative genomics reveals birth and death of fragile regions in mammalian evolutio" pdf
... multispecies breakpoint reuse test Technically, findings in [33] (limited breakpoint reuse between different lineages) are not in conflict with findings in [3] (rampant breakpoint reuse in chromosome ... the sites of rearrangements in the human lineage 18 out 162 breakpoints between MRD and QH were used in the human lineage, resulting in 18 = 162 ≈ 11% accurate prediction of human breakpoints, nearly ... 10 of them were used in the human lineage, resulting in 10 = 68 ≈ 16% accurate prediction of human breakpoints, again improving the accuracy of predictions These estimates indicate that TFBM can...
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báo cáo khoa học: "Quantitative analysis of nanoparticle internalization in mammalian cells by high resolution X-ray microscopy" pps
... required staining Figure shows that even without staining this imaging method can readily explore in detail the dissimilarities in the internalization of different AuNPs by different cell lines Specifically, ... Figure 8C and 8D (movie of different projection in Additional file 2) shows the results of specimen staining in revealing the detailed localization and shape of the nucleus and of the overall nanoparticle ... micrographs of the EMT and HeLa cells with AuNPs internalized After co-culturing with 500 μM naked AuNPs for 48 h, the endocytotic vesicles inside the cytoplasm of cell lines contained clusters of many...
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báo cáo khoa học: "Structure and expression of the maize (Zea mays L.) SUN-domain protein gene family: evidence for the existence of two divergent classes of SUN proteins in plants" pot
... proteins reside or function in the NE remains to be determined In addition to their difference in size and SUN domain locations, these protein subfamilies are distinct in other interesting ways ... plant nuclei contain multiple different SUN-domain proteins Models of the Topology of Plant SUN-domain Proteins The two structural classes of plant SUN-domain proteins found in maize, and shown ... in plants as well [33,63,64] In this regard, we find intriguing that two different laboratories [65,66] recently and independently mapped a recombination control QTL in maize to bin Page 13 of...
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A cullin 1 based SCF e3 ligase complex directs two distinct modes of neuronal pruning in drosophila melanogaster
... Attenuation of insulin signaling in cullin-1 mutant does not affect normal dendrite elaboration 86 3.7.5.2 Attenuation of insulin signaling in cullin-1 mutant promotes proximal severing of ... Attenuation of insulin signaling in cullin-1 mutant promotes proximal severing of major dendrites 88 Figure 22: Attenuation of insulin signaling does not rescue dendrite pruning defect in mical ... activating protein HECT homologous to E6 associated protein C-terminus Hh hedgehog IGF insulin like growth factor InR insulin receptor IPB infra-pyramidal bundles xv IPC insulin producing cell IRS insulin...
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IN SITU THREE-DIMENSIONAL RECONSTRUCTION OF MOUSE HEART SYMPATHETIC INNERVATION BY TWO-PHOTON EXCITATION FLUORESCENCE IMAGING
... family of signaling proteins Upon agonist binding to β receptors, a signaling cascade is launched involving the heterotrimeric G protein Gq, which activates phospholipase C, increasing inositol ... electrical responses in thin nerve segments Thus, a detailed delineation of the intracardiac sympathetic network structure would aid in better understanding the anatomical underpinnings of functional ... validation of an assay for imaging sympathetic nerves in the living mouse heart, and, second, use of this technique to obtain a three-dimensional wiring diagram of sympathetic nerves in a well-defined...
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Báo cáo y học: "Two-year Outcome of Turkish Patients Treated with Zotarolimus Versus Paclitaxel Eluting Stents in an Unselected Population with Coronary Artery Disease in the Real World: A Prospective Non-randomized Registry in Southern Turk
... treating single de novo lesions in patients with symptomatic coronary artery disease has been examined in the first four trials of the ongoing ENDEAVOR clinical trials program The results of these ... to maintain activated and clotting time of 250 to 300 s Patients received intracoronary nitroglycerin (0.1 to 0.2 mg) to achieve maximal vasodilatation before undergoing their initial and final ... patients treated in daily practice remains controversial The long-term safety of DESs remains in question (10-11) Despite the results of meta-analyses of randomized studies refuting these concerns...
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Báo cáo y học: "Ultra-low microcurrent in the management of diabetes mellitus, hypertension and chronic wounds: Report of twelve cases and discussion of mechanism of action"
... pathogenesis of insulin resistance in humans using magnetic resonance spectroscopy Obesity (Silver Spring) 2006;14 (Suppl 1): 34S–40S 31 Boden G Role of fatty acids in the pathogenesis of insulin resistance ... http://www.medsci.org Int J Med Sci 2010, cellular senescence (40-45) Source of reactive oxygen species in insulin secreting pancreatic β-cells and cells that are targets for insulin action is considered ... leg ulcers contain localized oxidative stress (15) The recent finding revealed that insulin resistance is associated in humans with reduced intracellular antioxidant (11) Interestingly, antioxidants...
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Tài liệu Action plan for the multi-level conservation of forest wetlands in the Mekong River Delta, Vietnam pdf
... sustainability financing mechanisms The rapid expansion of intensified agricultural cultivation and urbanization in the MD is strongly affecting wetland forest, resulting ultimately in shrinkage of ... accounting for approximately 57% (17% in the Lower U Minh and 40% in the Upper U Minh) of the total Melaleuca forest area In the U Minh coastal forest areas, the existing peat layers in the soil, ... countries, including Vietnam, became member of the Ramsar Convention The latter being an intergovernmental agreement offers a sound and stable framework for international cooperation in the area of wetland...
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Tài liệu Women''''s attitudes towards mechanisms of action of family planning methods: survey in primary health centres in Pamplona, Spain doc
... in inconsistent responses We found inconsistencies in 12.2% of the sample, indicating the difficulties in communicating the information about the mechanism of action To assess the influence of ... would consider using and would stop or continue using In addition, hypothetical choices were examined in terms of a non-specific "method of family planning" and not in terms of actual methods ... cross-sectional survey in a sample of women in reproductive age (18–49) from ten Primary Care Health Centres in various areas of Pamplona, Spain Women attend this kind of centre for obtaining primary care...
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Tài liệu Global action plan to control the spread and impact of antimicrobial resistance in Neisseria gonorrho pdf
... highlight the situation • maintaining a web-based system of posting treatment failures, including mapping and regularly updating the data on emerging resistant strains • collaborating with partners to ... The development of a pool of resistance genes and the ability of the gonococci to maintain these determinants of resistance within their genetic coding is part of the very nature of N. gonorrhoeae ... and principles for the prevention and care of STIs, to offer guidance to ministry of health officials who have the responsibility of developing and implementing interventions for the control of...
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Tài liệu Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans doc
... NADPÆmin)1Æmg protein)1 Determination of maintenance In order to calculate the amount of glucose used for maintenance, the wild-type strain A26 was used Four 100-mL aliquots of glucose minimal ... addition of acetate to the media containing glucose and propionate, the growth rate of both strains increased and the effect of propionate became less apparent Finally, in media containing acetate ... Determination of maintenance Maintenance is the energy that is used for survival of cells without any biomass formation Determination of maintenance was based on the inhibition of protein biosynthesis...
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Tài liệu Báo cáo khoa học: Extended half-life upon binding of destabilized intrabodies allows specific detection of antigen in mammalian cells pdf
... key enzyme in the biosynthesis of polyamines, whose interaction with antizyme, an ODC inhibitory protein, confers to the enzyme a half-life of about h The C-terminal end of ODC contains a PEST ... maintained in the cells by binding to antigen Generation of soluble binding-defective and cysteine-deleted mutants To demonstrate that the observed intracellular colocalization was the result of ... measuring protein mobility and activity in living cells Nature Cell Biol 3, 145–147 Bachmair A, Finley D & Varshavsky AK (1986) In vivo half-life of a protein is a function of its amino-terminal...
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Tài liệu Báo cáo khoa học: Two novel variants of human medium chain acyl-CoA dehydrogenase (MCAD) K364R, a folding mutation, and R256T, a catalytic-site mutation resulting in a well-folded but totally inactive protein pptx
... disruption of the local bonding and steric hindrance by the introduced amino acid Discussion In this paper we have described the protein folding, enzyme function, and thermostability of two novel ... procedure proving very effective in securing a pure protein product The results of kinetic analysis are displayed as Michaelis–Menten plots in Fig 3A The Km, Vmax (as determined by the Direct Linear ... to the purified protein (assuming no major change in the extinction coefficient of the bound cofactor in the case of the mutants) [15] The peak absorbance ratios showed first of all that the wild-type...
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Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx
... Penicillin-Streptomycin-Glutamine 1X (Gibco-Life Technology) Cell lines were maintained at 37 C in a humidied incubator containing 10% CO2 mixed with air Cytotoxicity assay Cells were seeded in 24- ... MSSAE in binding buffer (DMEM containing mgặmL)1 BSA and 25 mM Hepes at pH 7.5) At increasing time intervals, cells were washed repeatedly with NaCl/Pi and then treated with 0.6 M NaCl in NaCl/Pi ... growing cells When 125I-labelled MSSAE was incubated in binding buffer in the absence of cells no dimerization occurred (data not shown) These results indicate that a monomeric derivative of BSRNase...
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Health Problems and Disability of Elderly Individuals in Two Population Groups from Same Geographical Location docx
... living-instrumental activity of daily living (ADLIADL) without help e.g dressing, transferring from bed, toileting or taking bath, preparation of food, eating, shopping and walking Height and weight of the subjects ... Although in bi-variate analysis no gender difference was detected in disability, yet in logistic regression analysis after eliminating the influence of other factors, risk of disability increased in ... problems of the elderly in rural south India Indian Journal of Community Medicine 1990;15: 70-3 Khokhar A, Mehra M Life style and morbidity profile of geriatric population in an urbans community of...
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FINAL ACTION PLAN FOR IMPROVEMENT OF ENVIRONMENTAL PARAMETERS IN CRITICALLY POLLUTED AREAS “VISAKHAPATNAM CLUSTER” ANDHRA PRADESH docx
... Monitoring of VOCs in industrial areas during night times and also extending monitoring in the surrounding villages APPCB will ensure the linkage of Continuous Ambient Air Quality Monitoring Stations ... sweeping: The industry has procured a road sweeping machine with a cost of Rs 0.25 Cr in the year 2004 and cleaning the internal roads d Online monitoring: The industry has provided stack monitoring ... thereby reducing the movement of M/s VPT is in the process of number of trucks and dust fly-off mechanization of stocking, loading and unloading of dusty cargo like coal and iron ore to eliminate the...
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Báo cáo khoa học: Two types of replication protein A in seed plants Characterization of their functions in vitro and in vivo ppt
... checkpoint signaling in vivo It may function in the sensing of DNA damage [22] In contrast with the intensive study of RPA in animals and yeast, little is known about this protein in plants In 1997, ... protein–protein interaction assay) (Fig 3C–E) In the two- hybrid assay, the interaction between OsRPA70a and OsRPA32 yielded about 20% of the relative activity of the OsRPA32 and OsRPA14 interaction ... CM (1998) Interaction of human rad51 recombination protein with single-stranded DNA binding protein, RPA Nucleic Acids Res 26, 5388–5393 17 Stauffer ME & Chazin WJ (2004) Physical interaction between...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25