tumour of the lung

... [6]. Because of the rarity of monochorionic triplet pregnan- cies, there is no established guideline for management. The presence of an anomalous fetus further complicates the management of pregnancy. ... of the manuscript. YC was the director of the Maternal and Fetal Medicine Unit and par- ticipated in the design and revision of the manuscript. AIT was the director of the Reproductive Medicine ... to the mother to promote fetal lung maturation. The patient was readmitted to our unit at 34 weeks for uterine contractions and impaired fetal growth. The size of the lung lesion remained the same...

Ngày tải lên: 14/03/2014, 16:20

... function of the two isoforms, prompted us to analyze the organiza- tion and the promoter sequences (Fig. 4) of the two tryptase genes. The length of both genes, as evaluated from the size of the PCR ... these tissues at the mRNA level. The simultaneous expression of the two isoforms could be due to similar regulatory mechanisms in these specific tissues. The coexistence in the same organism of ... 60-fold higher in the case of BLT. The tissue-specific expression of the two tryptases was evaluated at the RNA level by analysis of their dif- ferent restriction patterns. In lung, only BLT was...

Ngày tải lên: 17/03/2014, 09:20

... cells of the transgenic animals, and thereby promoted the development of carcinoma of the lung. This mouse model should prove useful to the study of lung carcinogenesis and to the identification of ... in the lungs of mice allows control of the tim‐ Oncogenesis, Inflammatory and Parasitic Tropical Diseases of the Lung3 4 Section 3 Parasitic Tropical Lung Diseases 141 Chapter 7 Tropical Lung ... addition to the increased incidence of spontaneous lung tumor, these transgenic mice were more susceptible to the development of lung adeno‐ carcinoma after exposure to BaP. The risk of lung tumors...

Ngày tải lên: 23/03/2014, 14:20

... diagnosed in the right lung than the left lung. But, survival rates were nearly identi- cal for patients whose tumors arose in the right lung as compared to the left lung (Table 9.7). ‘Other’ category ... laterality). Subsite Over 40% of the lung cancers originated in the upper lobe no matter at which stage they were diagnosed. For stage I, 61.6% of the cancers originated in the upper lobe and 28.9% in the lower ... II, 53.9% of the cancers originated in the upper lobe and 34.1% in the lower lobe. For stages III, IV, and unknown, the origin Table 9.3: Cancer of the Lung: Number and Distribution of Cases...

Ngày tải lên: 29/03/2014, 01:20

... parameters may have distorted the data we observed to learn about the target. The distribution of both k inds of parameters can be updated with the help of the Bayesian theorem. The posterior target para- meters, ... of the uncertainty of the SMR as a result of confounding can be determined. We use the carbon black example to apply and illustrate this method. Details of the procedure and explanations of the ... data), that is the posterior distribution of the param eters. The factor 1/P(da ta) is often called the pro- portionality factor and this factor links the posterior with the product of likelihood...

Ngày tải lên: 20/06/2014, 00:20

... under the control of the same promoter that activates the expression of the target gene. Therefore, expression of the target gene leads to expression of the reporter, and the product of the reporter ... after the conversion of a proton into a neutron, with simultaneous emission of a neutrino (n). The positron is the antiparticle to the electron and the energy of emission can take a continuum of ... gene transfer to the lungs. The chapter describes the broad variety of agents that can be utilized. Similar agents can be developed for new molecular targets in the lungs as they are identified. 24...

Ngày tải lên: 29/06/2014, 11:20

... 60,514 cases of invasive lung cancer involving all races and both sexes obtained from the data for 1983–1987 of the S urveillance, Epidemiology, and End Results (SEER) Program of the National ... represents one lung cancer case for every 3 million cigarettes smoked. Thus, primary carcinoma of the lung is a major health problem with a generally grim prognosis. Pathology The term lung cancer ... tumors arising from the respiratory epithelium (bronchi, bronchioles, and alveoli). Mesotheliomas, lymphomas, and stromal tumors (sarcomas) are distinct from epithelial lung cancer. Four major...

Ngày tải lên: 07/07/2014, 01:20

... smoking-related, further increases the risk of developing lung cancer. The lung cancer death rate is related to the total amount (often expressed in "cigarette pack-years") of cigarettes ... are clinically localized at the time of presentation may be cured with either surgery or radiotherapy. The beneficial role of chemotherapy in NSCLC is in palliation of symptoms and improving ... smoking. The prevalence of smoking in the United States is 28% for males and 25% for females, age 18 years or older; 38% of high school seniors smoke. The relative risk of developing lung cancer...

Ngày tải lên: 07/07/2014, 01:20

... cancers other than lung cancer, nor in lung cancers that have KRAS mutations. These EGFR mutations, often associated with amplification of the EGFR gene, usually confer sensitivity of these lung ... cases the development of EGFR TKI resistance is associated with the development of another mutation in the EGFR gene (T790M mutation), or amplification of the c-met oncogene. However, other ... syndrome) genes may develop lung cancer. First-degree relatives of lung cancer probands have a two- to threefold excess risk of lung cancer or other cancers, many of which are not smoking-related....

Ngày tải lên: 07/07/2014, 01:20

... inappropriate palliative rather than curative treatment. Often the paraneoplastic syndrome may be relieved with successful treatment of the tumor. In some cases, the pathophysiology of the paraneoplastic ... uncommon (1%), as are the renal manifestations of nephrotic syndrome or glomerulonephritis (≤1%). Chapter 085. Neoplasms of the Lung (Part 5) Clinical Manifestations Lung cancer gives rise ... and 97). Although 5–15% of patients with lung cancer are identified while they are asymptomatic, usually as a result of a routine chest radiograph or through the use of screening CT scans, most...

Ngày tải lên: 07/07/2014, 01:20

... Neoplasms of the Lung (Part 6) Diagnosis and Staging Screening Most patients with lung cancer present with advanced disease, raising the question of whether screening would detect these tumors ... (whether the tumor can be entirely removed by a standard surgical procedure such as a lobectomy or pneumonectomy), which depends on the anatomic stage of the tumor, and operability (whether the ... diagnosis of epithelial malignancy and distinguish small cell from non-small cell lung cancer. Staging Patients with Lung Cancer Lung cancer staging consists of two parts: first, a determination of...

Ngày tải lên: 07/07/2014, 01:20

... <2 cm distal to carina but without involvement of carina; or associated atelectasis or obstructive pneumonitis of entire lung for Staging of Lung Cancer. Chest 111:1710, 1997; with permission. ... metastatic pulmonary tumor nodule(s) in the ipsilateral nonprimary tumor lobe(s) of the lung are classified as M1. Source: Adapted from CF Mountain. Revisions in the International System ... exams of a non- bloody, non- exudative pleural or pericardial effusion that clinical judgment dictates is not related to the tumor, the effusion should be excluded as a staging element and the...

Ngày tải lên: 07/07/2014, 01:20

Ngày tải lên: 07/07/2014, 01:20

Ngày tải lên: 07/07/2014, 01:20

Ngày tải lên: 07/07/2014, 01:20

Ngày tải lên: 07/07/2014, 01:20

Ngày tải lên: 07/07/2014, 01:20