Ngày tải lên: 10/08/2014, 09:22
Ngày tải lên: 12/08/2014, 15:21
Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"
... Pseudopapillary Neoplasm of the pancreas (SPN) is the correct description regarding the terminology. 4,5,6 Despite the increases in recognition of characteristics of this tumor, which include ... in the uncertainty of the strategy for its treatment. While further delineati n g the clinicopathological and radiological features, and summarizing the surgical therapy strategy of this tumor, ... (SPN), the experience with the management of disseminated disease is very limited in the literature 6 , therefore, attention to the therapy strategy of this neoplasm in the future may allow a...
Ngày tải lên: 25/10/2012, 11:40
Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt
... initiation of apoptosis through the mitochondrial pathway. The key event in the mito- chondrial pathway is the release of proapoptotic fac- tors from the mitochondrial intermembrane space into the cytosol, ... release of cytochrome c and second mitochondria-derived activator of caspase (Smac ⁄ DIABLO) allows for the formation of the apoptosome, a complex that enables the activation of caspases within the ... reported that the N-terminal portion of Bid needs to be cleaved and degraded to allow tBid to interact with its partners [15]. Removal of the N-terminal portion also seems to be necessary to allow the...
Ngày tải lên: 16/02/2014, 09:20
gift of the magi literary terms
... landmark. Theme: The central idea in this story is the love between Delia and James and the sacrifices that they make to please the other. Climax: The most exciting part of the story is when the characters ... Gift of the Magi Literary Terms This Gift of the Magi literary terms synopsis includes the terms referenced directly from the short story. This well known story, ... purchase the other a gift. She sells her hair to buy him a watch fob; he sells his watch to buy her tortoise shell hair combs. Understanding the Gift of the Magi Literary Terms Narrator: The story...
Ngày tải lên: 02/03/2014, 15:21
Báo cáo khoa học: Structural mobility of the monomeric C-terminal domain of the HIV-1 capsid protein pptx
... relationship between S 2 and the location of structural elements (Fig. 4). Furthermore, the R ex terms are distributed throughout the 3D structure of the protein, and most of them are large (Fig. 4); the exception ... responsible, from a thermodynamic point of view, for the binding of the monomeric species of CAC? We have previously discussed the variation in the free energy of binding as a function of the changes ... another tumbling time) occurs at the N (Gln11 and Glu15) and at the C-termini of the first a-helix (Lys26); in the long disordered loop (Thr42); and at the N- (Gly62, Ala64), and C-termini of the...
Ngày tải lên: 07/03/2014, 06:20
Báo cáo khoa học: The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B1 and B2 bradykinin receptors potx
... site because the presence of detergent or membrane lipids influences the formation of a helical structure. These authors proposed that activation of the receptor, and subsequently of the G protein, ... and the position number is indi- cated. The grey box outside the membrane indicates the region of the putative cytosolic helix 8 as found in the crystal structure of bovine rhodopsin [24]. The ... interruption of the amphipathic structure of B 1 wt helix 8 in B 1 wt and B 1 KB 2 through the presence of a serine in position of V323 leads to a strong attenuation of the IP signal; (b) substitution of...
Ngày tải lên: 07/03/2014, 16:20
Overview of the Aesthetic Medical Device Market docx
... les of Select Participants in the Aesthetic Medical Device Market (cont’d.) Overview of Aesthetic Medical Devices Market p.10 Section 3 Pro les of Select Participants in the Aesthetic Medical ... resurface and was the developer of the Fraxel platform of lasers. ã Solta markets the Thermage radiofrequency technology focusing on skin tightening. The Thermage system is the only device ... as of 2/10/2009. Thomson Consensus Estimates. Overview of Aesthetic Medical Devices Market p.5 Section 3 Pro les of Select Participants in the Aesthetic Medical Devices Market Overview of the...
Ngày tải lên: 07/03/2014, 17:20
Monochorionic triamniotic triplet pregnancy with a co-triplet fetus discordant for congenital cystic adenomatoid malformation of the lung ppt
... of the manuscript. YC was the director of the Maternal and Fetal Medicine Unit and par- ticipated in the design and revision of the manuscript. AIT was the director of the Reproductive Medicine ... to the mother to promote fetal lung maturation. The patient was readmitted to our unit at 34 weeks for uterine contractions and impaired fetal growth. The size of the lung lesion remained the same ... tomography of the infant at 3 months: two cystic masses in the middle lobe of the right lung, suggesting congenital cystic adenomatoid malformation (arrows)Figure 4 Computerized tomography of the infant...
Ngày tải lên: 14/03/2014, 16:20
Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot
... the total levels of soluble APP remaining constant irrespective of the presence or absence of BACE1. The levels of APPsa increased to account for the loss of APPsb (soluble C-terminally truncated ... is the b-site APP-cleaving enzyme 1 (BACE1). Here, we investigated the effects of genetic manipulation of BACE1 on the processing of the APP family of proteins. BACE1 expression regulated the ... charac- terize the impact of BACE1 inhibition as a putative therapy for the treatment of AD. We found that the de novo production and the endogenous levels of ICDs were not reduced by deletion of BACE1....
Ngày tải lên: 15/03/2014, 10:20
Báo cáo khoa học: Conformational properties of bacterial DnaK and yeast mitochondrial Hsp70 Role of the divergent C-terminal a-helical subdomain pdf
... that of DnaK. The twofold reduction of the K SV values estimated for mtHsp70 both in the absence and the presence of ATP (Table 2) supports the existence of differences in the Trp environment of ... to three endotherms at 43.5, 57.5 and 74 °C. The first and second endotherms have been assigned to the unfolding of the N-terminal ATPase domain and the C-terminal PBD, respectively, whereas the third ... Replacement of the complete a-helical domain in KKCC resulted in disappearance of the intermediate endotherm, which was assigned to the PBD. In contrast to what was observed for the other proteins, the...
Ngày tải lên: 16/03/2014, 22:20
Báo cáo khoa học: Bovine tryptases cDNA cloning, tissue specific expression and characterization of the lung isoform ppt
... function of the two isoforms, prompted us to analyze the organiza- tion and the promoter sequences (Fig. 4) of the two tryptase genes. The length of both genes, as evaluated from the size of the PCR ... these tissues at the mRNA level. The simultaneous expression of the two isoforms could be due to similar regulatory mechanisms in these specific tissues. The coexistence in the same organism of ... 60-fold higher in the case of BLT. The tissue-specific expression of the two tryptases was evaluated at the RNA level by analysis of their dif- ferent restriction patterns. In lung, only BLT was...
Ngày tải lên: 17/03/2014, 09:20
Oncogenesis, Inflammatory and Parasitic Tropical Diseases of the Lung Edited by Jean-Marie Kayembe potx
... cells of the transgenic animals, and thereby promoted the development of carcinoma of the lung. This mouse model should prove useful to the study of lung carcinogenesis and to the identification of ... addition to the increased incidence of spontaneous lung tumor, these transgenic mice were more susceptible to the development of lung adeno‐ carcinoma after exposure to BaP. The risk of lung tumors ... regulation of the activity or action of EGFR and other members of the RTK family have been involved in multiple cancers, including of brain, lung, breast and ovary. Furthermore, in many tumors EGF-related...
Ngày tải lên: 23/03/2014, 14:20
Cancer of the Lung pot
... ages. Laterality Tumors were more frequently diagnosed in the right lung than the left lung. But, survival rates were nearly identi- cal for patients whose tumors arose in the right lung as compared to the ... laterality). Subsite Over 40% of the lung cancers originated in the upper lobe no matter at which stage they were diagnosed. For stage I, 61.6% of the cancers originated in the upper lobe and 28.9% in the lower ... II, 53.9% of the cancers originated in the upper lobe and 34.1% in the lower lobe. For stages III, IV, and unknown, the origin Table 9.3: Cancer of the Lung: Number and Distribution of Cases...
Ngày tải lên: 29/03/2014, 01:20
báo cáo hóa học:" Epigenetic control of the ubiquitin carboxyl terminal hydrolase 1 in renal cell carcinoma" doc
... during the differentiation of renal tubules representing the origin of clear cell renal cell carcinoma (RCC) and in the regula- tion of the cell cycle of parietal epithelial cells of the Bow- man's ... controlling the protein turnover of the kidney. There exists conflicting evidence concerning the role of UCHL1 in tumorigenesis varying from anti -tumor to pro- tumor properties depending on the tumor ... partial methylation of the UCHL1 promoter DNA in the RCC cell line MZ2862RC, characterized by methylation of some of the CpG dinucleotides within the core region of the UCHL1 promoter while other CpG sites...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học: " Bayesian bias adjustments of the lung cancer SMR in a cohort of German carbon black production workers" pdf
Ngày tải lên: 20/06/2014, 00:20