... Do you, Doctor, swear to tell the truth, the whole truth and nothing but the truth? Oded Yitschaky1, Michael Yitschaky1 and Yehuda Zadik2,3* Abstract We are in the era of “evidence based medicine” ... you, Doctor, swear to tell the truth, the whole truth and nothing but the truth? Journal of Medical Case Reports 2011 5:179 Submit your next manuscript to BioMed Central and take full advantage ... Many in the medical and dental communities highly value randomized clinical trials as the gold standard of care and undervalue clinical reports The aim of this editorial is to emphasize the benefits...
Ngày tải lên: 11/08/2014, 00:23
... via the rmdup (paired reads) and rmdupse (single reads) command [10] It was also used for SNV identification, using the pileup command with the -c option and default settings The SNVs were then ... contributions ETC participated in the design of the study, performed analyses, and drafted the paper AS performed analyses and processed the cDNA reads KVS supervised the sequencing of gDNA and ... and processed the gDNA reads JPS sequenced the gDNA and cDNA JMM performed analyses and processed the gDNA reads ELH provided expression data JJG collected the cohort, prepared the samples, and...
Ngày tải lên: 09/08/2014, 20:22
Báo cáo y học: " The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion" potx
... by the Dutch AIDS fund (#5003 and #2005021 to BB and #1028 to InekeB), and by grants from the Netherlands Organization for Scientific Research (NWO – Medical Sciences, to EvA, InekeB, and BB, and ... μg/ml (wt) and 7.96 μg/ml (N386D)), confirming that the involvement of the 386 glycan to the 2G12 epitope is variable and/ or context dependent We next tested the accessibility of the CD4BS The HIV1LAI ... Pantophlet and D Burton, personal communication) These data also indicate that it is probably not the chemical property of the introduced amino acid that causes the increased sensitivity, but rather the...
Ngày tải lên: 13/08/2014, 06:20
Báo cáo y học: "Fully-spliced HIV-1 RNAs are reverse transcribed with similar efficiencies as the genomic RNA in virions and cells, but more efficiently in AZT-treated cells" ppt
... of the viral cDNA species from the earliest steps of RTion, i.e the minus strong-stop DNA synthesis (ssDNA) and the first strand transfer (represented by the U3 product) (Fig 1) Up to now, there ... lentiviral and retroviral vectors – design, biosafety, and production Gene Ther 2005, 12:1089-1098 Authors' contributions LH and MM have conceived the study and analyzed data LH performed the laboratory ... ZM help, and helped in drafting and finalizing the manuscript MM wrote the manuscript All authors read and approved the final manuscript Acknowledgements The authors thank M Biart for the 42CD4...
Ngày tải lên: 13/08/2014, 09:21
Tài liệu Nothing But Net 2009 Internet Investment Guide 34 pptx
... Zealand: This material is issued and distributed by JPMSAL in New Zealand only to persons whose principal business is the investment of money or who, in the course of and for the purposes of their ... maker that makes a market in the options of The9 Limited, and therefore such specialist may have a position (long or short) in the options of the issuer and may be on the opposite side of public ... Limited and Bombay Stock Exchange Limited and is regulated by the Securities and Exchange Board of India Thailand: JPMorgan Securities (Thailand) Limited is a member of the Stock Exchange of Thailand...
Ngày tải lên: 15/12/2013, 10:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 1 docx
... by ISPs and application and content providers in order to improve the end user experience The WSJ article also reported that Microsoft and Yahoo! have quietly removed themselves from the Net ... value by the end of 2008 Meanwhile, the U.S auto industry sits on the verge of bankruptcy without a government bailout All of these events significantly impacted the overall economy, and we are ... in the near and longer term • • Near term, we expect B&M bankruptcies and especially store closings to lead to pricing pressure, and thus margins pressure on the survivors in both online and...
Ngày tải lên: 15/12/2013, 10:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 2 docx
... likely to remain quite slow in the first half of the year as companies and management teams try to understand the scope and length of the economic downturn Further, we think sellers are likely ... January 2009 To the extent acquirers are willing to part with cash, we expect them to have the resources: large Internet and media companies continue to generate significant cash flows At the four large-cap ... think the market climate is unlikely to moderate significantly in the near term in order for the IPO window to reopen soon Given the lead time involved in most deal activity, we think it is therefore...
Ngày tải lên: 15/12/2013, 10:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 3 pdf
... its monetization gains from Project Panama, and 3) we think advertisers are more likely to cut their spend with the other search engines and stick with the leader in a recession On a query volume ... ComScore and J.P.Morgan estimates The Future of Ad Networks The ad network space is becoming increasingly competitive as new ventures are launched and as Google, Yahoo!, AOL, and Microsoft enter the ... be gathered and ads are targeted In order to most effectively target the ads, publishers need to have access to user behavior on multiple sites to collect data and to repeatedly show ads to the...
Ngày tải lên: 15/12/2013, 10:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 4 doc
... influence, and each bidder has equal access to the media; • Increased role of technology to automate and provide a common platform; and • Elimination of intermediaries and their margins The Value ... especially as the retail landscape experiences upheaval and the dislocation of several incumbent players Additionally, we think broadband penetration will continue to rise, and we see broadband penetration ... Entering the ad network space would allow large cap Internet companies to lever their existing sales force, technology, and publisher relationships in expanding their product offering The sales...
Ngày tải lên: 15/12/2013, 10:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 5 pdf
... Men and Women %, among respondents who indicated they shop online, that indicated they had made purchases in category Men Books, music, videos and other media Computer and videogames software and ... Apparel and accessories (includes shoes, handbags and jewelry) Electronics (includes television and stereo equipment) Toys 50.5% Women Apparel and accessories (includes shoes, handbags and jewelry) ... Amazon, have started collecting the NY sales tax while appealing the ruling Overstock.com, on the other hand, has chosen to drop its NYbased affiliates and not charge the tax Given that many states...
Ngày tải lên: 24/12/2013, 17:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 6 ppt
... 18% through their favorite links, and 17% from their carrier’s portal Yahoo! Mail has the largest unique audience with 14M unique monthly users in May, with Google Search and The Weather Channel ... middleware, user-friendly interface, and applications The first phones based on Android debuted in the fourth quarter of 2008 By bringing the Internet developer model to the mobile market, it is hoped ... Mobile Media Survey and Q1 2008 Device Census Company Initiatives Google Works on Android Google decided to address distribution difficulties head-on with the creation of the Open Handset Alliance,...
Ngày tải lên: 24/12/2013, 17:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 7 pptx
... the major sites, Facebook and LinkedIn posted the most impressive usage growth, and across the group of social networking sites, user minutes worldwide grew 30%+, according to comScore data And ... through the first nine months of the year Although the rising tide lifted most boats, Facebook was a particular beneficiary, and is now the leader in terms of worldwide unique users and time ... Y/Y in the most recent quarter • Not a fad – a technology that solves users’ problems With another year of rapid growth behind us, there remains little doubt that there is very strong demand by...
Ngày tải lên: 24/12/2013, 17:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 8 pdf
... that users have the ability to opt out of the feature A year later, the news feed is one of the central aspects of the Facebook interface, and other sites, including MySpace and LinkedIn, have ... the operators of the apps for access to the networks’ superior stream of traffic Alternatively, they may make the applications paid-for by users, and split the revenue with the app developers ... Nevertheless, we believe the track record of social sites’ development suggests users have a strong desire for expression and for an avenue to share what is going on in their lives – and the desire...
Ngày tải lên: 24/12/2013, 17:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 9 pptx
... believe brand advertisers are very cautious to have their brand placed next to content that clearly reflects the brand identity and message and conveys brand values, we find it unlikely that brand ... digital printing, as more and more people are not only uploading their photos, but they are also sharing them with friends and family Furthermore, many social networking and blog sites have added ... with special effects and music and then paste it onto their own site, to simple widgets that update weather and stock quotes on users’ computers Fragmentation Fuels Widget Demand Historically, portals...
Ngày tải lên: 24/12/2013, 17:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 10 doc
... site then purchases the student materials and ships the items directly to the school, along with a disposable camera and guidelines for preparing feedback packages The teacher photographs the ... think the cloud computing model offers compelling solutions, both on the applications and on the services side, and expect fairly rapid growth in usage in both arenas in the coming months and years ... occasionally called on-demand applications These tools tend to be more sophisticated (and expensive) than the small business and consumer-targeted offerings described above Nevertheless, they can take advantage...
Ngày tải lên: 24/12/2013, 17:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 11 pdf
... Access the Internet Given the increase in Internet accessible computers, broadband penetration, and per capita wealth, the home has become the preferred place for most users to access the Internet, ... Morgan estimates Broadband and Mobile Continue Rapid Growth The number of users with broadband Internet access grew 80% Y/Y to 163M (78% of total users) by the end of 2007, and to 214M (85% of total ... higher and an annual income of Rmb2,000 or more Media and Instant Messaging Are Among the Most Popular Internet Uses According to the Dec-07 CNNIC survey, online music is the most popular use of the...
Ngày tải lên: 24/12/2013, 17:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 12 ppt
... over the whole For example, Beijing only accounts for ~5% of property sales in China, and a similar ad spending for the city as well We note that both Sina and Sohu have the majority of their ... bandwidth costs We expect these to lead to margin upside for the sector in 2009 and 2010: (1) After the 2008 Olympics, portals will likely reduce high editorial costs For Sohu in particular, the ... many in the market have been pricing in a “hard landing” scenario in which China's GDP growth could dip into 6-8% oya territory While the few percentage points difference in the top and bottom...
Ngày tải lên: 24/12/2013, 17:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 13 pdf
... (MMORPG) These games are not simply about shooting and killing or finding treasures and saving the princess, as in some other games MMORPG are community-based, and players can interact with other ... but Low Internet Usage According to the National Development and Reform Commission, Department of Small and Medium-Sized Enterprises figures, as of F’05, there were 43 million SMEs in China These ... creates the need for newer software and also drives consumer demand As a result, the game software industry is relatively less vulnerable in an economic slowdown, compared to other industries and...
Ngày tải lên: 24/12/2013, 17:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 14 doc
... with other game players They communicate through instant messengers in the game Once players have been playing for a certain period, they start building their seniority and respect within the gaming ... playing the game The first option is the most effective way to deal with the problem However, as many online game operators only purchase games from other developers and not have access to the source ... ago and remains one of the top games in the country Any Piracy Issues of Online Games? Online games are designed to get around the piracy issue There are two sets of software – server software and...
Ngày tải lên: 24/12/2013, 17:15
Tài liệu Nothing But Net 2009 Internet Investment Guide 15 ppt
... Search Internet Yandex likely to lead in paid search We estimate Yandex’s share of the paid search market at 67% in 2007 We forecast stable market shares for Yandex and Rambler and a higher share ... domestic companies Yandex and Rambler, which could have lost market share if Google acquired Begun We view the news as neutral for Rambler and positive for Begun and note the government’s increasing ... benefits on their dollar spending Although we believe the downside for NHN is limited at the current trading range, we think the stock is less likely to rebound in the near term, unless the market...
Ngày tải lên: 21/01/2014, 23:20