treatment of focal brain ischemia with viral vector mediated gene transfer
Báo cáo khoa học: Modulation of the endocannabinoid system by focal brain ischemia in the rat is involved in neuroprotection afforded by 17b-estradiol pdf
Ngày tải lên :
23/03/2014, 07:20
... associated with altered endocannabinoid metabolism, the activity of FAAH was measured in cortices and striata from rats with focal brain ischemia Two hours of MCAo, with or without h of reperfusion, ... in accordance with the guidelines of the European Community Council Directive 86 ⁄ 609, included in D.M 116 ⁄ 1992 of the Italian Ministry of Health Focal cerebral ischemia Brain ischemia was ... in a variety of animal models of acute cerebral ischemia, including transient and permanent MCAo [18–20], photothrombotic focal ischemic brain damage [21], and global forebrain ischemia [22,23]...
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báo cáo hóa học: " Inhibition of NF-κB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia" docx
Ngày tải lên :
19/06/2014, 22:20
... in DMEM medium with 5% FBS (without antibiotics), and were transfected using FuGene reagent (Promega) with 1.5 μg of NF-κB-luc reporter construct vector or insertless expression vector (pBluescript) ... sets of animals (C) Treatment with BW-B 70C prevented the nuclear translocation of p65 subunit of NF-κB (i-iii); the vehicletreated animals showed nuclear translocation (ii) and treatment with ... via inhibition of iNOS gene expression (Fig 3B) This gene expression was quantified by real time PCR analysis of mRNA h after reperfusion Activation of NF-κB is involved in iNOS gene expression...
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Báo cáo y học: "Treatment of focal degenerative cartilage defects with polymer-based autologous chondrocyte grafts: four-year clinical results" pdf
Ngày tải lên :
09/08/2014, 13:22
... for the treatment of traumatic and focal osteoarthritic cartilage defects of the knee [26] The aim of the present study was to evaluate ACI using BioSeed®-C for the treatment of mild degenerative ... fixing the graft Radiographswith autologous chondrocyte grafts cartilage defects prior to treatment of patients with focal degenerative (BioSeed®-C) to treatment with autologous chondrocyte grafts ... rate of 10% corresponds to earlier findings describing rates of failure in ACI with other implants of between 5% [12] and 13% [20] These patients with focal degenerative defects treated with...
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Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"
Ngày tải lên :
25/10/2012, 11:40
... Different methods of decompressive craniectomy in the treatment of TBI Different methods of decompressive craniectomy have been developed for, or applied to, decompression of the brain at risk for ... together with dura opening, and it was believed that this could maximize brain expansion after removal of part of the skull However, opening the dura with no protection for the underlying brain ... prognosis of severe traumatic brain injury, part 1: Guidelines for the management of severe traumatic brain injury J Neurotrauma 2000;17:451-533 Piek J Decompressive surgery in the treatment of traumatic...
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Báo cáo y học: "Treatment of proximal femur infections with antibiotic-loaded cement spacers"
Ngày tải lên :
26/10/2012, 09:53
... of soft-tissue shortening and provision of sufficient infection therapy is the usage of temporary, antibiotic-loaded cement spacers [5, 7, 14, 24] Although their indication in the treatment of ... properties of our spacer Therefore, the enhancement of the spacer’s stability should be the aim of further investigations, either with the insertion of a metallic endoskeleton or with K-wires ... Fig 2: Evaluation of the hip joint function by the Merle d’ Aubigne score at the site of spacer implantation in the treatment of proximal femur infections Fig 3: Evaluation of the hip joint function...
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báo cáo hóa học:" Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors" docx
Ngày tải lên :
18/06/2014, 15:20
... randomized trial of surgery in the treatment of single metastases to the brain New England Journal of Medicine 1990, 322:494 Jellinger K, Volc D, Grisold W: Multimodality treatment of malignant gliomas ... within the extravascular compartment of early, less mature and smaller malignant brain tumor colonies, whether primary or metastatic Significance of the luminal glycocalyx layer of the BBTB of ... physiologic upper limit of the pore size within the BBTB of malignant brain tumors and the blood-tumor barrier (BTB) of malignant peripheral tumors[73,74], the pore size within the BBTB and BTB...
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báo cáo hóa học:" Two levels above and one level below pedicle screw fixation for the treatment of unstable thoracolumbar fracture with partial or intact neurology" pot
Ngày tải lên :
20/06/2014, 04:20
... and with kyphosis of 28-degrees patient with showing1 unstable L1 fracture b) lateral radiogram of a showing preoperative a) AP and b) lateral radiogram of a patient with unstable L1 fracture with ... and their treatment, including patient parameters, mode of trauma, level of injury, type of fracture, injury surgery interval, kyphotic angles (pre-operative, post-operative, loss of kyphosis), ... routine protocol in our clinic for the treatment of osteoporosis The patients were followed with serial physical examinations and radiographs With the use of lateral radiographs centered over the...
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báo cáo hóa học:" Treatment of refractory hip pain with sodium hyaluronate (Hyalgan©) in a patient with the Marshall-Smith Syndrome: A case report" pot
Ngày tải lên :
20/06/2014, 04:20
... on, and FDA-approval of, VS is primarily for use in the treatment of knee osteoarthritis, it has also been used successfully in small trials for the treatment of arthritis of the temporomandibular, ... Hyaluronate for the Treatment of Patients with Periarthritis of the Shoulder Clinical Therapeutics 1995, 17(5):946 Page of 18 Smith G, Myers S, Brandt K, Mickler E: Effect of Intra-articular Hyaluronan ... blood, milliliter (ml) of iopamidol-300 (Isovue-300©) dye was injected, verifying intra-articular spread of the dye (Figure 2) This was followed with an injection of mL of 0.5% preservative-free...
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báo cáo hóa học:" Treatment of refractory hip pain with sodium hyaluronate (Hyalgan©) in a patient with the Marshall-Smith Syndrome: A case report" ppt
Ngày tải lên :
20/06/2014, 07:20
... on, and FDA-approval of, VS is primarily for use in the treatment of knee osteoarthritis, it has also been used successfully in small trials for the treatment of arthritis of the temporomandibular, ... Hyaluronate for the Treatment of Patients with Periarthritis of the Shoulder Clinical Therapeutics 1995, 17(5):946 Page of 18 Smith G, Myers S, Brandt K, Mickler E: Effect of Intra-articular Hyaluronan ... blood, milliliter (ml) of iopamidol-300 (Isovue-300©) dye was injected, verifying intra-articular spread of the dye (Figure 2) This was followed with an injection of mL of 0.5% preservative-free...
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Báo cáo toán học: " Successful treatment of severe accidental hypothermia with cardiac arrest for a long time using cardiopulmonary bypass - report of a case" docx
Ngày tải lên :
20/06/2014, 20:20
... is associated with hypoxia because of sinking until being completely covered with water Immersion is associated with accidental hypothermia because of sinking until being covered with water except ... clinical setting, it is often difficult to determine whether hypoxia associated with submersion or severe accidental hypothermia associated with immersion is the cause of cardiac arrest due to ... a.m.) Soon, movement of his limbs appeared, the size and reactivity of the pupils became almost normal, and spontaneous breathing became adequate Aspiration of a large amount of seawater was suspected...
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Báo cáo y học: "Residual sleep disturbance and risk of relapse during the continuation/maintenance phase treatment of major depressive disorder with the selective serotonin reuptake inhibitor fluoxetine" docx
Ngày tải lên :
08/08/2014, 23:21
... greater burden of residual sleep disturbance is associated with a higher risk of relapse among fluoxetine responders with MDD during the continuation/maintenance phase of treatment with either fluoxetine ... laboratory evidence of hypothyroidism without adequate and stable replacement therapy; or had a history of nonresponse to an adequate trial of a SSRI (defined as a 4week trial of ≥ 40 mg of fluoxetine ... role of residual sleep disturbance as a predictor of relapse in MDD Therefore, the purpose of the present study was to explore the impact of residual sleep disturbance on the Page of risk of relapse...
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Báo cáo khoa học: "Treatment of pathologic spinal fractures with combined radiofrequency ablation and balloon kyphoplasty" doc
Ngày tải lên :
09/08/2014, 04:21
... stabilization of the bone [7] Radiofrequency ablation (RFA) is a relatively new method for the treatment of painful bone metastases It was initially introduced for the treatment of osteoid osteoma ... for the treatment of spinal metastatic tumors with good results [17,18] Discussion Spinal complications of osseous metastatic disease may have detrimental effects on the quality of life of cancer ... the risk of symptomatic vascular leakage during the cement augmentation To the best of our knowledge, the combination of RFA with BKP has not been described previously for the treatment of metastatic...
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Báo cáo y học: "A second-generation autologous chondrocyte implantation approach to the treatment of focal articular cartilage defects" ppsx
Ngày tải lên :
09/08/2014, 10:21
... suggest that implantation of autologous chondrocyte-seeded BioSeed-C is an effective treatment option for the regeneration of posttraumatic or osteoarthritic defects of the knee Recent developments ... and degenerative cartilage defects in a group of patients suffering from chronic post-traumatic or degenerative cartilage lesions of the knee Clinical outcome was assessed in 40 patients with ... assessment of the biological and clinical outcomes; a better definition of the cellularity requirement of functional cartilage development; and evaluation of potential harmful effects of local...
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báo cáo khoa học: "Development of a duodenal gallstone ileus with gastric outlet obstruction (Bouveret syndrome) four months after successful treatment of symptomatic gallstone disease with cholecystitis and cholangitis: a case report" pps
Ngày tải lên :
11/08/2014, 02:22
... to formation of a biliary enteric fistula Fistula formation is a complication of 2% to 3% of all cases of cholelithiasis with associated episodes of cholecystitis [2] Obstruction of the biliary ... alanine aminotransferase (AST and ALT) levels of 51 U/L and 83 U/L, a moderate elevation of the g glutamyl transpeptidase (GGT) level of 487 U/L and an alkaline phosphatase (AP) level of 368 U/L ... Contrast material in the lumen of the gallbladder (notice thickening of the wall of the gallbladder and communication with the duodenal bulb) #: Contrast material in the lumen of the descending duodenum...
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Báo cáo y học: " Aripiprazole Augmentation in the Treatment of Military-Related PTSD with Major Depression: a retrospective chart review" docx
Ngày tải lên :
11/08/2014, 15:22
... course of treatment In addition to providing psychoeducation, the standard psychiatric treatment at the clinic includes symptom management, treatment of comorbid disorders, and management of functional ... discontinued prior to the initiation of aripiprazole The sample was derived from a retrospective chart review with approval from the Office of Research Ethics of the University of Western Ontario Consent ... characteristics of the sample are presented in Table Of the 27 participants, almost all were men (n = 26, 96.3%), with an average age of Page of Table Baseline characteristics of the sample Demographic...
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Báo cáo y học: "Treatment of active lupus nephritis with the novel immunosuppressant 15-deoxyspergualin: an open-label dose escalation study" pps
Ngày tải lên :
12/08/2014, 15:22
... development of cerebral lupus; and progression of the disease that did not justify the continuation of DSG therapy (for example, treatment with OCS (prednisolone equivalent) >1 mg/kg/day or treatment with ... regarded as an exclusion criterion Treatment protocol Patients were treated for a maximum of nine treatment cycles with DSG Treatment was started with a daily dose of 0.5 mg/kg normal body weight/day, ... time since first diagnosis of SLE, time since first Page of 12 diagnosis of LN, LN WHO type, pretreatment of LN within six months before study start The diagnosis of LN was confirmed in all patients...
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Báo cáo y học: "Treatment of experimental adjuvant arthritis with a novel folate receptor-targeted folic acidaminopterin conjugate" doc
Ngày tải lên :
12/08/2014, 15:22
... synthesis of a Page 17 of 18 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 new generation of targeted therapeutics Part 3: Folate conjugates of aminopterin hydrazide for the treatment of ... the enzymatic conversion of dihydrofolic acid to tetrahydrofolic acid by DHFR and the disappearance of the cofactor nicotinamide adenine dinucleotide phosphate at Page of 18 340 nm The results ... full activation of macrophages [49] Using our standard condition of a 2-hour pulse with the test article plus a 70-hour chase, TG-macs were treated with 100 nM EC0746 without or with excess FA...
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Báo cáo khoa học: "Bench-to-bedside review: Antidotal treatment of sulfonylurea-induced hypoglycaemia with octreotide" pdf
Ngày tải lên :
12/08/2014, 22:22
... albumin 544 Elimination of octreotide from plasma had an apparent halflife of 1.5 hours, as compared with 1–3 with the natural hormone somatostatin The duration of action of octreotide is variable ... reported the case of a patient with chronic renal failure who developed recurrent and prolonged episodes of hypoglycaemia associated with the use of SUA He was hospitalized with neuroglycopenic ... is limited with long-term therapy by the ability of octreotide to delay absorption of carbohydrate and to inhibit the secretion of growth hormone and glucagons Long-term treatment with octreotide...
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Báo cáo y học: " Down regulation of the high-affinity IgE receptor associated with successful treatment of chronic idiopathic urticaria with omalizuma" pot
Ngày tải lên :
13/08/2014, 13:22
... eighth treatment visit at which time she was able to completely withdraw from cyclosporine use At the start of omalizumab treatment, she would experience only a generalized sensation of pruritus without ... dose first and second generation antihistamines without success Montelukast offered no benefit when added to treatment with antihistamines However, relief was obtainable with oral prednisone (20 ... during treatment with omalizumab Prior to treatment with omalizumab and after consent was obtained, peripheral blood was obtained from the patient and from a control subject with no history of urticaria...
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Báo cáo khoa học: Dynamic association of MLL1, H3K4 trimethylation with chromatin and Hox gene expression during the cell cycle ppt
Ngày tải lên :
23/03/2014, 06:20
... the rest of the cell cycle (10 and 20 h), correlating with the expression of the gene (Fig 6C,D) The correlation of promoter occupancy of MLL1, H3K4 trimethylation and RNAP II with Hox gene expression ... HoxA7 and HoxA10 gene promoters was also correlated with their respective expression profiles (compare Fig 6A,B with Fig 6C,D) In the case of the HoxA7 gene promoter, the recruitment of RNAP II and ... trimethylation in HoxA5 gene regulation during cell cycle progression The association of a certain amount of RNAP II with the HoxA5 gene promoter at 20 h (although much lower in comparison with that at...
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