toxicity to the human fetus of chemical substances and drugs

... over whether workers are prepared to meet the demands of the production system because of their levels of commitment or due to their subordination to management and their subsequent coercion to comply ... Technology and Job and Work Design Chris W Clegg is Professor of Organisational Psychology and Deputy Director of the Institute of Work Psychology at the University of Sheffield He is a Co-Director of the ... For Today and Tomorrow The holistic and integrative nature of lean manufacturing is to be found in his initial comments that the business world is a trinity of the market, the factory and the...

Ngày tải lên: 06/07/2014, 15:31

... over whether workers are prepared to meet the demands of the production system because of their levels of commitment or due to their subordination to management and their subsequent coercion to comply ... Technology and Job and Work Design Chris W Clegg is Professor of Organisational Psychology and Deputy Director of the Institute of Work Psychology at the University of Sheffield He is a Co-Director of the ... For Today and Tomorrow The holistic and integrative nature of lean manufacturing is to be found in his initial comments that the business world is a trinity of the market, the factory and the...

Ngày tải lên: 06/07/2014, 15:34

... middle and high frequency parts of the vocal range and the angular frequencies to( F) and amplitudes a(F) of formants The first four cues dp, to {h are properties of a single spectral slice, and the ... The other segment-based cues contrast steadystate formant values at the centre of a segment with values at entrance and exit boundary They describe the context of a segment without going to the ... identity of a segment has been established The overall architecture of the recognition task is shown in Figure At Stage 1, the recogniser checks for the presence of the manner elements h and ? ED~...

Ngày tải lên: 31/03/2014, 04:20

... by Gyftopolous and Beretta [19]: (14) Gyftopolous and Beretta Among all the states of a system with given values of energy, the amounts of constituents and the parameters, there is one and only ... Zeroth and Third Laws of Thermodynamics The first law is the skeleton of thermodynamics; the second law is its flesh The first gives structure; the second gives life By comparison, the zeroth and 18 ... temperature of system B is equal to the temperature of system C, then the temperature of system A is equal to the temperature of system C (If TA = TB and TB = TC , then TA = TC ) Or, to put it...

Ngày tải lên: 24/04/2014, 17:14

... Remain) in the UK (18.9%), preference of living in the UK (7.4%) and the presence of family and friends in the UK (7.1%) (Figure 4) All respondents were asked to report their 'main' and 'other' reasons ... policy that fail to factor in the aspirations and needs of doctors who have already migrated to the UK are likely to disrupt the career paths of many non-European doctors, many of whom have spent ... of the European Working Time Directive, curtailing the working hours of doctors, along with the increased resource investment in the NHS at the end of the last century resulted in an influx of...

Ngày tải lên: 18/06/2014, 17:20

... contributed to the embryo, the resultant offspring will be chimeric (up to ca 50% of animals) The ESC contribution to a mouse can high (up to ca 80% of the cells), and will often include the germline ... attributed to the fortuitous removal or inhibition of IF(s) [43] Seminal fluid reportedly contains an inhibitory factor (IF-1) that appears to actively block the binding of exogenous DNA to sperm and to ... very costly and technically demanding, due in large part to the need to remove embryos from the female, to manipulate the embryos and finally to return the embryos to the reproductive tract By contrast,...

Ngày tải lên: 03/11/2012, 10:01

... Sequence of the a domain of rhMT-1a, showing the connectivities of the four divalent metal cations to the 11 cysteinyl sulfurs The numbering of the cysteines (1–11 starting from the N-terminus) and the ... initially to the a domain, thereby leading to formation of the M4a cluster prior to formation of the M3b cluster, demonstrating that the individual binding constants of divalent metal ions for the ... sites within the two domains This was followed by coordination of the fourth and fifth metal ions to the a domain for completion of the metallation of this domain prior to filling of the b domain...

Ngày tải lên: 19/02/2014, 00:20

... intensities of these bands corresponded to the positive reactivity of the target protein and may therefore have been degradation products of the truncated protein The sensitivity of the anti-GST serum to ... to residues 365–385 of the hTF C-lobe The mAb F11 blocked binding of hTF to the TFR; this suggests the antibody epitope contains residues that are located in the vicinity of the ligand–receptor ... observation that the HFE protein and hTF bind to the same or closely overlapping sites [14] adds further support for the role of the helical domain of the TFR in binding to TF since most of the residues...

Ngày tải lên: 30/03/2014, 11:20

... irrespective of the mother's sleep phase, the fetus was observed to be active, as inferred from the increased number of its movements On the other hand, locomotor activity of the fetus was 7–8 ... isoelectrical line of the external ECG of the fetus, calculated by hour and a graph of hourly fetal movements was plotted At nighttime, external ECGs of the fetus and EEGs of the mother were recorded ... regard to natural changes in the functional state of the fetus related to the run of its biological clock (Research works 1980– 1986); and Determination of the time of onset and formation of fetal...

Ngày tải lên: 10/08/2014, 09:20

... the history of the person's illness, the symptoms and course of the illness, possible causes, the impact of the illness on the individual and the family in terms of day -to- day life and social ... causes, the methods of treatment provided and the ideology/theology on which they were based, the efficacy of the treatment and the reasons for this, and views of other forms of treatment and possible ... demonstration of the efficacy of healing in effecting the transformation of the person from madness to health; from asociality to humanity Two of the pastors interviewed had collected photographs of men and...

Ngày tải lên: 11/08/2014, 14:21

... results, and wrote most of the software CT wrote some of the software CT and MP contributed to discussions on algorithms BL, CT, MP, and SLS wrote the manuscript Additional data files The following ... suffixes of the query At each step, the size of the range either shrinks or remains the same When the algorithm completes, rows beginning with S0 (the entire query) correspond to exact occurrences of ... explanation of how the reverse complement is incorporated The first 28 bases on the high-quality end of the read are termed the 'seed' The seed consists of two halves: the 14 bp on the high-quality...

Ngày tải lên: 14/08/2014, 21:20

... ● “It [the petition] demands that the traffic of cials of Grahamstown ‘return to being polite public servants, working for the good and safety of the community, rather than the rude and of cious ... shine) Ultimately from the Indo-European root kand- (to shine), which is the ancestor of such words as candent, candid, candle, chandelier, candidate, candor, incense, incandesce, and incendiary ● ... appeals to the prejudices and emotions of the people to gain power verb tr and intr To manipulate an issue; to speak or act in the manner of a demagogue From Greek demagogos (leader of the people),...

Ngày tải lên: 25/10/2013, 16:20

... for the best Then there are others who deliberately not want to know anything about the activities of the company They want to study the “pure” movement of the stock price with the belief that they ... Investor There are two key features of the growth in sales and earnings: the rate of growth and the stability of the growth Conscious Investor provides proprietary tools to measure both of these ... put the two charts together, we see how they track each other Sometimes the price moves ahead of the earnings per share and sometimes it is the other way around But over time they move together...

Ngày tải lên: 09/12/2013, 20:15

... using the PUSH, PSHD, POP, and POPD instructions The PUSH and POP operations push the accumulator on the stack or pop the top of the stack to the accumulator respectively PSHD and POPD the same ... beginning of the loop, and the repeat-end (RE) the end of the loop These registers are initialized automatically by the processor, but they are available to the user in case he needs to save them On the ... one of the operands resides in the accumulator, and the result is also placed in the accumulator (The only exceptions is the multiplication operation examined later.) The other operand can either...

Ngày tải lên: 25/12/2013, 06:16

Ngày tải lên: 13/02/2014, 12:20

... farmer of the Post Office, furnished to the Secretary of State "a perfect list" of all officers in the Post Office According to this list there were eight Clerks of the Roads, viz.:—Two of the Northern ... case of attack The proprietors of these coaches are determined to have the passengers and property protected and for the safety of both have ordered their[Pg 35] coachmen to keep together to make ... sent to the Right Hon Wm Pitt, representing the great benefits received from the plan, and requesting a continuance of the same, together with the extension of the same plan to other parts of the...

Ngày tải lên: 17/02/2014, 02:20

... knowledge and compulsory subjects, and of course, to the number of total ECTS that, as was previously noted, have to add up to a total of 240 The content of the studies resulting in the award of a ... information, to determine the relative weights of each of the subjects of the structure in terms of their relevance to the labour market, they requested the opinion of academics with over years of experience ... trimesters of 2000 and 2001, to systematize the type of jobs that were being offered, and thus, the demands of the labour market These job offers were finally classified into separate categories of employment...

Ngày tải lên: 18/02/2014, 11:20

... been found to be specific and potent HAD inhibitors To check for covalent modifications of the enzyme, the effect of the inhibitor on the molecular mass value of HAD was measured; instead of an adduct ... cleavages in the center of the protein to form additional loose ends to be denatured out of the ball of spaghetti The ESI spectrum of the 200 kDa human complement C4 glycoprotein (of 1714 residues ... substitution; MS ⁄ MS will then show the substituent positions of different isomers A problem for MS ⁄ MS of either the peptides for the bottom-up approach or of the proteins for the top-down approach...

Ngày tải lên: 18/02/2014, 16:20

... In the absence of MgCl2, the affinity of Fpg for the THF:C ligand was 1.6-fold higher than for the THF:A ligand The presence of Mg2+ had little effect on the binding of Fpg to the THF:C ligand and ... of organic acids, amino acids, inorganic phosphate and nucleic acids [27] To explore the dependence of the activity and specificity of Fpg and OGG1 on general ionic strength and the presence of ... To independently evaluate the effects of ionic strength and Mg2+ on the activity and specificity of OGG1, we measured the apparent values of k2 and k3 under conditions of low salt (KPi only) and...

Ngày tải lên: 18/02/2014, 18:20

... investigated the effect of divalent cations on the binding of ICAM-4 transfectants to the I domains of CD11a and CD11b and compared the results to the divalent cation requirements of ICAM-1 and ICAM-2 ... The most efficient inhibition of the binding of ICAM-1 L cell transfectants to the I domains was obtained with the ICAM-1 mAb LB-2 reacting with the first domain of ICAM-1 and the mAbs GP8914 and ... mapped to domains and of the ICAM-1 molecule [44] None of these anti-ICAM-1 mAbs showed inhibitory effects on adhesion of ICAM-2 or ICAM-4 L cells MAbs to ICAM-2 and ICAM-4 inhibited the binding of...

Ngày tải lên: 20/02/2014, 11:20