total cost function and risk of drm

... Copyright of BMJ: British Medical Journal is the property of BMJ Publishing Group and its content may not be copied or emailed to multiple sites...

Ngày tải lên: 26/08/2016, 04:49

... age, height and weight of the neonate, and personal identifiers for both mother and child [24] Use of loratadine, other antihistamines, IVF drugs, antidiabetics and epileptics As a part of the tax-funded ... hypospadias codes, and 25 children with both ICD-8 and ICD-10 codes Using these codes, a total of 319 cases of hypospadias were identified (anytime postpartum) in the cohort of 65,383 male births ... postpartum and maternal use of antihistamines according to time of exposure, odds ratios (OR) and 95% confidence intervals (CI) Time of exposure Exposure 30 days before conception and first trimester...

Ngày tải lên: 02/11/2012, 10:09

... (18% of the total land area) if we assume that at least 50% of the area currently classified as ice (Greenland and Antarctica) and tundra would become wetland and the current wetland area of 12.8 ... change because of the resistance of pollens and spores to decay, and their ubiquity and abundance (Traverse 2008) Wetlands are excellent sources of pollen and spores and like macrofossils, palynomorph ... times the area of wetlands that exist today would be needed Natural and manmade wetlands are important sources of methane, and our conservative estimate of doubling of the total wetland area in...

Ngày tải lên: 18/02/2014, 20:20

... constituent of the Tic motor complex (see below) The present minireview provides a short description of recent advances in the understanding of the channel-, motor- and regulatory components of the ... position and function of the long C-terminal tail on the other hand remains a matter of controversy [10,11,13–15] According to one hypothesis, the hydrophilic Tic110-Ct faces the stroma, where it functions ... characterization of the single domains provided valuable insight into the possible functional role of Tic40: the Sti1-like region of Tic40 was shown to be functionally equivalent to the Sti1 domain of human...

Ngày tải lên: 07/03/2014, 03:20

... elevation of NADH/NAD+ and acetyl-CoA/CoA ratios The rise in these ratios is sensed by the rapid and reversible E3 and E2 reactions which act to increase the proportion of the lipoyl groups of E2 and ... Surface residues of the L2 domain of E2 that are required for activating PDK3 and PDP1 Panels A and B show opposing sides of space-filled models of the human L2 domain The position of Lys173 (lipoylated ... NADH/NAD+ ratio of 0.1 and acetyl-CoA/CoA ratio of 0.2 The most responsive human kinase isoform is PDK2 [17,18] The greater extended reach of the reduced and acetylated lipoyl group over that of the oxidized...

Ngày tải lên: 17/03/2014, 09:20

... FEBS 3195 Function and regulation of ABCA1 K Nagao et al ABCA1 whereas direct binding of photoactive cholesterol to ABCA1 could not be detected [74]; however, analysis of the functions of ABCA7 ... cholesterol available to cold MbCD The effect of the reduction of plasma membrane SM content on the function of ABCA1 is quite different from that on the function of ABCG1, since ABCG1-mediated cholesterol ... Hayden MR (2003) Efflux and atherosclerosis: the clinical and biochemical impact of variations in the ABCA1 gene Arterioscler Thromb Vasc Biol 23, 1322–1332 Function and regulation of ABCA1 Oram JF...

Ngày tải lên: 22/03/2014, 15:21

... applied p < 0.01) The Page of sample size (205 patients and 300 controls) was enough to reach a power of 75% at a p = 0.05 (for a power of 80%, a total of 225 patients and 338 controls should be ... article as: Coto et al., Functional polymorphisms in genes of the Angiotensin and Serotonin systems and risk of hypertrophic cardiomyopathy: AT1R as a potential modifier Journal of Translational Medicine ... exclude the presence of asymptomatic LVH A total of 150 of these controls were examined through electrocardiography to exclude the existence of cardiac diseases All the patients and controls were...

Ngày tải lên: 18/06/2014, 16:20

... organization and management of safety and health precautions Economic survival and economic competition concerns quite often might override basic health and safety concerns Another reason is that SMEs often ... Mikkelsen K: The effects of firm size on risks and reporting of elevation fall injury in construction trades Journal of Occupational and Environmental Medicine 2003, 45:1074-1078 Page of 19 Hannerz H, ... Fatal-Injury Risk of Construction Workers by Occupation and Cause of Death Human and Ecological Risk Assessment 1998, 4:1371-1390 21 McVittie D, Banakin H, Brocklebank W: The effect of firm size...

Ngày tải lên: 20/06/2014, 00:20

... minimum available bandwidth (bottle- Assume we have on the end-to-end link i : A total available bandwidth of κw , and a requested bandwidth of xw , we must find the bandwidth-type cost function: f (xw ... increment of requested bandwidth and the total requested bandwidth: xw∆xw w , +∆x • The decrement of cost which is proportional to: – The ratio between the decrement of the remaining available bandwidth ... current value of f (xw + ∆xw ), so this current value of the cost function depends on: • The previous cost: f (xw ), • The increment of cost which is proportional to: – The previous cost: f (xw...

Ngày tải lên: 08/07/2014, 17:08

... the creation of institutions or cultures that advocate the rule of law and the protection of human rights vi Globalization has a lot of benefits, however, it also has risks too First of all, globalization ... Everything has its pros and cons and globalization is not an exception In this essay, we will examine the benefits and risks of globalization, as well as personal view of the author if we should ... [report] University of Sydney, p x Shangquan, G 2000 Economic Globalization: Trends, Risks and Risk Prevention [report] United Nations, p xi Pubs.aeaweb.org 2007 Transportation Costs and International...

Ngày tải lên: 18/07/2014, 14:39

... indicator-CMT and California mastitis test and risk of violative antimicrobial residues Table Observed frequencies (%) of milk samples (n = 239) positive and negative for mastitis using the CMT, SCC, and ... ± standard error of the mean for cows in each group SCC = somatic cell count; CMT = California mastitis test; n = number of observations Table †Mean ± SEM of SCC and CMT in non -infected and ... sector of Kiambu District, Kenya pp 14- California mastitis test and risk of violative antimicrobial residues 18 PhD Thesis, University of Nairobi 1997 13 Osteras O, Edge V, Martin S Determinants of...

Ngày tải lên: 07/08/2014, 17:22

... hypersomnia item score, total insomnia burden (the sum of items 4, 5, and 6), or total hypersomnia burden (the sum of items 22, 23, and 24) entered separately Gender and chronicity were added ... laboratory evidence of hypothyroidism without adequate and stable replacement therapy; or had a history of nonresponse to an adequate trial of a SSRI (defined as a 4week trial of ≥ 40 mg of fluoxetine ... of relapse in MDD Therefore, the purpose of the present study was to explore the impact of residual sleep disturbance on the Page of risk of relapse of MDD during the continuation/maintenance...

Ngày tải lên: 08/08/2014, 23:21

... localization of metastatic disease in patients with various kinds of malignancies The uptake of the FDG in the normal thyroid gland is homogenous and of low intensity; the normal thyroid gland is usually ... thyroid nodules and demonstrated that the sensitivity and specificity of FDG-PET/CT were 60% and 91% The positive predictive value and negative predictive value of the FDG-PET/ CT was 75% and 83% Jeong ... drafted the manuscript and contributed to conception and design BJC contributed to acquisition and analysis of data WCP, JSK and SSJ participated in the design of the study and revised ir critically...

Ngày tải lên: 09/08/2014, 04:21

... antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials JAMA 2006, ... some of these issues and has raised the concern of a potentially serious increased risk for malignancy However, the interpretation of the results needs to take into account the unexpected and ... populations studied, and of too short a duration to generate robust estimates of any possible increased risk for rare adverse events A meta-analysis, such as that conducted by Bongartz and coworkers...

Ngày tải lên: 09/08/2014, 08:22

... WBRT and boost The 1-year survival and brain control rates were 65% and 70% after WBRT plus SRS, and 63% and 78% after surgery plus WBRT and boost, respectively Based on the present results and ... in its design and coordination, and drafted the manuscript GL, GT and AR participated in study design, analysis and interpretation of data, and helped to draft the manuscript EC and MFO performed ... 24% for Q3, and 51% for Q4 control were 14.1 months and 10 months, respectively The 1-year and 2-year survival rates were 58% and 24%, and respective brain control rates were 43% and 22% Sixteen...

Ngày tải lên: 09/08/2014, 09:20

... a mean disease duration of 15 years and mean age of 61.8 years (range, 17 to 87 years) for CV events, duration and features of RA, CV disease risk factors, and HLA–DRB1 and RAGE Gly82→Ser genotypes ... analysis of CV risk factors and features of RA for risk of a time-dependent CV event among 232 patients Coefficient (β) Risk factor Treatment with statins for hyperlipidemia SE Wald χ2 Risk ratio ... fibrils of amyloid and advanced glycation end products (AGEs) [15] AGEs are the products of nonenzymatic glycation and oxidation of proteins that form with aging, diabetes and renal failure, and...

Ngày tải lên: 09/08/2014, 10:20

... toxicity and graded from to on the RTOG scale (Table 1) However, these trials often not specify the incidence and severity of treatment related cardiovascular (thrombotic) toxicities In fact, of the ... brachytherapy procedures may be at a high risk for the development of DVT Several retrospective studies of the perioperative morbidity and mortality of gynecologic brachytherapy have been performed ... compared with pelvic and para-aortic radiation for highrisk cervical cancer New England Journal of Medicine 1999, 340(15):1137-1143 Benedetti-Panici P, et al.: Neoadjuvant chemotherapy and radical surgery...

Ngày tải lên: 09/08/2014, 10:20

... adipose mass and the risk of joint replacement Most studies have employed BMI as a measure of obesity, and have shown a consistently positive association between BMI and the risk of both knee ... country of birth, and highest level of education, stratifying by gender, representing an approximate change of one standard deviation for each of the adiposity measures ated with the risk of knee ... participated in the design of the study and the acquisition of data, and reviewed the manuscript FMC participated in the design of the study, helped with the interpretation of data, and reviewed the manuscript...

Ngày tải lên: 09/08/2014, 13:22

... our past findings of associations between reproductive factors and the risk of developing RA in the NHS [56] Data on pack-years of smoking (product of years of smoking and packs of cigarettes per ... hypothesized that low total and free testosterone levels and low DHEAS levels measured before the onset of disease would be associated with an increased risk of RA in women Excess estrogen and progesterone ... of data, and manuscript preparation PAF participated in the study design and interpretation of the data ST participated in the study design, statistical analysis and interpretation of data, and...

Ngày tải lên: 09/08/2014, 14:22

... pairs of HIV-1-infected mothers and their uninfected children and 20 pairs of mothers and children who were HIV-1infected Analysis of the HLA-G DNA sequences of exons 2, 3, 4, 6, 7, a part of 8-3'UTR ... resulted in 85.7% (12/14) of the mother-child pairs showing dissimilarities of banding profiles among the HIV-1-non-transmitting group and 90% (18/20) similarity of banding profiles among the HIV-transmitting ... restriction of digested PCR products of exons 6/7 and exon 8-3'UT region of HLA-G DNA obtained from blood samples, Representatives enzyme Pst I Representatives of digested PCR products of exons 6/7 and...

Ngày tải lên: 10/08/2014, 05:20