... constructing and using theories in a self- conscious way helps to inject some rigor into these processes.6 For these reasons, both theorists and practitioners seek a clear and powerful understanding ... coerce or bribe others to support sanctions it favors, especially if it commits itself early and irrevocably to costly actions in support of those policies.10 On the other hand, such a state may be ... deployments, investments in the command -and- control apparatus, and operational nuclear doctrines Since this work focused on the interplay between military postures and the likelihood of inadvertent...
Ngày tải lên: 01/06/2014, 00:53
... r 3 < 2, < s ≤ ∞, s 1.8 then u is smooth Berselli and Galdi 11 have extended the range of r and s to 2/r 3/s and 3/2 < s ≤ ∞ When s ∞, Chen and Zhang 12 also see Fan et al 13 refined it to the ... H Kozono and Y Taniuchi, “Bilinear estimates in BMO and the Navier-Stokes equations,” Mathematische Zeitschrift, vol 235, no 1, pp 173–194, 2000 17 J Chen and X Zhu, “A note on BMO and its application,” ... elementary and short proof of 1.18 by 1.11 For given ≤ r < q < ∞, there exists a positive integer n and θ ∈ 0, such that − θ · 1/2n r θ − θ /2n · 1/r By the Holder r < q < 2n r and 1/q θ ·...
Ngày tải lên: 22/06/2014, 02:20
MORPHOGENESIS THE CELLULAR AND MOLECULAR PROCESSES OF DEVELOPMENTAL ANATOMY pptx
... caterpillar (was he so wrong?) and hence within the egg At this point, reasonable scientific study was abandoned by many biologists and wish became the father of thought and the grandfather of observation: ... looking at tissue organisation and thinking about the processes by which it is laid down, and here I have in mind not only developmental biologists, but also anatomists and pathologists It might be ... how tissue organisation is laid down, we also have to understand the interactions between the cells and the environment in which they operate The range of cell and molecular mechanisms underpinning...
Ngày tải lên: 05/03/2014, 11:21
The future of internal audit is now Increasing relevance by turning risk into results pot
... laws and regulations to combat bribery and corruption, multinational organizations are under increasing pressure to improve their anti-bribery and anti-corruption compliance programs to detect and ... Based on the mandate and strategic vision, align initiatives to key business risks and key operational and financial priorities Make sure that processes, methodologies and tools are up to date, ... changes and grows, its risk, control and compliance activities often become fragmented, siloed, independent and misaligned This has an impact on both the governance oversight and the business itself...
Ngày tải lên: 15/03/2014, 23:20
Báo cáo khoa học: Non-enzymatic developmental functions of acetylcholinesterase – the question of redundancy docx
... well as F428 and ˚ D432, and the 60VDATT motif within 2A of G298 and R299, as well as 329–332 (DPEG), 350–351 (LR) and 437–440 (IPR) It would thus appear to be a possibility that AChE and Mer may ... developing nervous system) and collagen IV, which interact and selfassociate to form a scaffold to which other ECM components, such as nidogen ⁄ entactin, fibronectin and perlecan, bind [27] ECM ... antibodies showed a common epitope, centred on the 40 PPMGPRRFL and 90RELSED sequences, which are linked by a salt bridge between 46R and 94E Docking of the mouse AChE and laminin structures showed...
Ngày tải lên: 30/03/2014, 02:20
báo cáo hóa học: " The role of interleukin-12 in the heavy metal-elicited immunomodulation: relevance of various evaluation methods" potx
... expression as well as the up- or down- regulation factor for each gene relative to controls and based on an efficiency corrected mathematical model and a pair-wise fixed reallocation randomization test ... wash buffer and centrifuged at 200 × g for Finally, test buffer (250 mL) was added, and samples were analyzed on FACSCalibur (BD Biosciences) using the supplied cytometer setup beads and the CellQuest™ ... citation purposes) Journal of Occupational Medicine and Toxicology 2008, 3:25 http://www.occup-med.com/content/3/1/25 behavioral deficits and increases brain serotonin and dopamine metabolism in rats...
Ngày tải lên: 20/06/2014, 00:20
Authority leadership marketing making content the cornerstone of customer engagement and relevance
... their pipelines and upsell and cross-sell customers with credible, strategic content Companies, both global and emerging, realize the need to use content to drive brand relevance and authority ... is being driven by an upsurge in executive participation in the strategic procurement process, as well as the ready availability of meaningful decision support content, affinity groups, and professional ... strategies and effectiveness auditing protocols Rather than delivering self- serving messages, they must speak to relevant themes and topic areas, author higher-quality content that is more visual and...
Ngày tải lên: 30/07/2014, 16:37
Báo cáo sinh học: "On the relevance of three genetic models for the description of genetic variance in small populations undergoing selection" docx
... algorithm, initiated by Hospital [8] and developed by Fournet et al [7], uses the Monte-Carlo principle and provides the mean values and standard deviations for genetic mean and variance over time a 2.2 ... en bon accord avec la théorie gaussienne quand il est utilisé avec un grand nombre de locus, l’approche stochastique le rendant de plus beaucoup plus souple que les deux modèles algébriques Dans ... loci, IM and SFM depart from FFM only after 20 generations, while for 10 loci, they both depart from FFM as early as generation and with loci, IM and SFM depart from FFM after generations and 6,...
Ngày tải lên: 09/08/2014, 18:22
báo cáo khoa học: " Field transcriptome revealed critical developmental and physiological transitions involved in the expression of growth potential in japonica rice" potx
... complex and suppresses flowering in LD, and further speculated that the formation of the Hd1/DTH8/HAP5 and Ghd7/DTH8/ HAP5 complex might be associated with the suppression of flowering by the downregulation ... procedures of the t-test and fold change (FDR < 0.05 and FC > 3) and were used to generate the heat map Based on similarity of expression patterns, we selected 357 upregulated and 333 downregulated genes ... of Pi uptake and translocation [49,50] Five precursors of miR399 were downregulated in leaves before the initiation of panicle development and the potential rice ortholog, OsPHO2 [47], was upregulated...
Ngày tải lên: 11/08/2014, 11:21
báo cáo khoa học: " Developmental localization and the role of hydroxyproline rich glycoproteins during somatic embryogenesis of banana (Musa spp. AAA)" ppt
... contributions JS and CX planned experiments, CX and CB performed experiments, CX, JS, TT and CB analyzed data and prepared data presentation, JS, CX, TT and DM wrote the manuscript All authors read and approved ... extensins from rice [42] Monocot barley and rice protoplasts contain JIM19 and JIM20 extensin-like epitopes [41,43], while there were both similarities and differences to the labelling pattern ... embryos while this ECM was disrupted by treatment with 3,4-DHP Conclusions Immunoblot and immunofluorescence analyses revealed two HRGP epitopes JIM11 and JIM20 in ECs and in various developmental...
Ngày tải lên: 11/08/2014, 11:21
báo cáo khoa học: " Integration of tomato reproductive developmental landmarks and expression profiles, and the effect of SUN on fruit shape" pot
... blots and together with JH and DL the transcript profiling analysis CR and TM conducted the floral landmark study NW and TM conducted the fruit landmark study EvdK supervised the project and conducted ... fifth landmark and occurred between 10 and 12 dpa (Fig 7E and 7F) highlighting the beginning of cotyledon growth The 13–16 dpa embryo was torpedo shape, marking the sixth landmark (Fig 7G and 7H) ... and molecular regulation of fruit and plant domestication traits in tomato and pepper J Exp Bot 2007, 58:3841-3852 Tanksley SD: The genetic, developmental, and molecular bases of fruit size and...
Ngày tải lên: 12/08/2014, 03:20
Báo cáo y học: "spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response" doc
... ± 6.15/HPF and CD15+ neutrophils 3.88 ± 5.75/HPF (Figure 2) Within the population of MPO+ cells, 63.5% and 36.5% of cells were MNCs and PNCs in AS patients, respectively, and 65.1% and 34.9% of ... group and might be sufficient to orchestrate an immune response In our study, mast cells as a source of IL-17 were much less frequent than in RA patients [20] and psoriasis patients [21], and ... Authors’ contributions HA and JS designed the study, analysed the data and drafted the manuscript RH, PW and RS participated in the data collection, performed the data analysis and helped in the drafting...
Ngày tải lên: 12/08/2014, 17:21
Báo cáo khoa học: "Clinical review: Tokyo – protecting the health care worker during a chemical mass casualty event: an important issue of continuing relevance" ppt
... with the police, and should decontaminate victims because this is an essential and The use of PPE is as important as decontamination itself PPE is mainly used in the receiving and decontamination ... mechanical ventilators and other devices that also use the lines The pressure demand type level B PPE is somewhat more expensive than the continuous supply air line type, and requires the user ... compressed air is delivered by a mask with a regulator that supplies air on demand Although the former type permits easier breathing and is safe, it consumes 140 l/min compressed air, placing a...
Ngày tải lên: 12/08/2014, 22:21
Báo cáo y học: " HIV-1 Accessory Protein Vpr: Relevance in the pathogenesis of HIV and potential for therapeutic interventio" ppsx
... proposed as a therapy for HIV-1 and has been shown to suppress HIV-1 replication in infected mononuclear cells and to suppress Vpr mediated downregulation of IL-12 and other cytokines [117,209] ... immune suppression Interestingly, the upregulation of NKG2 ligands by Vpr is also related to DCAF-1 binding in an ATR related mechanism, which suggests that these ligands may not be readily upregulated ... mechanism by inducing IB and reducing NF-B activity [209] Vpr downregulates NF-B inducible cytokines, including IL-2, IL-12, TNF-a, and IL-4, and chemokines, MIP-1a, MIP-1b, and RANTES [209-211]...
Ngày tải lên: 13/08/2014, 01:20
Báo cáo y học: "Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease" potx
... kinase-1 and integrin-linked kinase are target genes of PPARβ The upregulation of these genes together with the down- regulation of PTEN led to an increase of Akt1 activity in keratinocytes and suppressed ... involved in lipid uptake and by repressing key genes implicated in lipid metabolism and efflux [74] Regulation of mitosis and apoptosis by PPARs in pre-clinical models PPARα PPARα ligands such as ... and Macphee CH Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN Curr Biol 2001, 11:764-768 129 Brockman JA, Gupta RA and DuBois RN Activation...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: "Relevance of laboratory testing for the diagnosis of primary immunodeficiencies: a review of case-based examples of selected immunodeficiencies" doc
... variant of WAS [29-32] and is characterized by thrombocytopenia and small platelets Typically, serious immunological anomalies are uncommon in XLT, though elevated IgA and IgE and mild eczema can ... control and standardization of techniques, methods, platforms and reference values is essential to successful and accurate outcomes for immunological analyses within the laboratory, and clinical ... monocytes, B cells and platelets Intracellular flow cytometry was performed on B cells and monocytes of a healthy control and monocytes from the patient (since B cells were absent) (Figure 1A and 1B) The...
Ngày tải lên: 13/08/2014, 13:22
Báo cáo y học: "The organisation of the stress response, and its relevance to chiropractors: a commentary" pdf
... [64], and alteration of network functioning [65] Damage associated with changes in the regulation of the HPA axis cause deficits in memory, cognition and learning [30], and decreased accuracy and ... thirst and cardiovascular mechanisms as well as in the organization of autonomic and endocrine responses The arcuate nucleus projects to preoptic LHRH neurons, and is involved in the regulation ... subcoeruleus, and the solitary and dorsal vagal nuclei [24] With arrangements of ascending and descending fibres from various areas including the limbic system, medial hypothalamus, and the autonomic...
Ngày tải lên: 13/08/2014, 14:20
Báo cáo sinh học: "The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery" pptx
... found in macrophages and microglia, and causes demyelination, vacuolation and gliosis Again, the mechanism by which HIV causes CNS pathology is not well understood The gp120 (Env) and Tat proteins ... anemia virus (EIAV) [58] and maedi/visna virus (MVV) [59] For CAEV and MMV viral infection of macrophages seems to induce an inflammatory response involving macrophages and CD4+ and CD8+ T cells It ... Mis2, Mlvi2, and 4, c-myb, c-myc, N-myc, Notch1, Pal1, Pim1 and 2, prolactin receptor, Pvt1, Tiam1 and Tpl2) Page of 13 (page number not for citation purposes) Genetic Vaccines and Therapy 2004,...
Ngày tải lên: 14/08/2014, 19:22
AN INVESTIGATION INTO THE USE OF PRESENTATION-REFLECTION ASSIGNMENTS IN THE AMERICAN STUDIES SYLLABUS AT ULIS-VNUH: RELEVANCE AND EFFICACY AS PERCEIVED BY LECTURERS AND STUDENTS Nghiên cứu về việc Sử dụng Bài tập Thuyết trình-Viết Thu hoạch trong Bộ môn H
... American Studies course include group presentations on a certain topic and individual reflection essays of group members on that same presentation and topic Other groups have to write reports/evaluation ... presentations (or better support with proper facts and figures), demand better sharing and discussion about the topic before presentation, increase discussion time and effort after each presentation, or ... sharing and discussion discussion/seminar about topics before presentation Consistent presentation Reduce presentationfollow -up questions reflection group's size Presentations be better supported...
Ngày tải lên: 30/03/2015, 14:00