... Statistical Methods for the Analysis of Survival Data in Cancer Clinical Trials Thesis submitted in accordance with the requirements of the University of Liverpool for the degree of Doctor in Philosophy ... Illustration of the behaviour of the Step distribution 126 7.7 Illustration of the behaviour of the Trapezium distribution 127 7.8 Figure to show the performance of the ALC for normal, ... Illustration of prior and posterior densities for a selection of parameters for the analysis of GemCap data 124 7.5 Illustration of fitted survival function for a) vague and b) informative
Ngày tải lên: 03/09/2021, 22:51
... or a textual analysis Much of the data in the field of bioinformatics is gathered and integrated from a wide range of publications, data stores, and other products of research Information related ... domain expert, the tasks performed by the researcher in the course of a typical analysis, and, importantly, the structure and content of the data used in their published research They were intentionally ... knowledge the present work is the first taxonomy of tasks written in the context of the domain of biological pathway analysis The nearest existing work is that of Saraiya et al [4], which builds off of
Ngày tải lên: 19/11/2022, 11:49
Web geospatial visualisation for clustering analysis of epidemiological data
... GEOSPATIAL VISUALISATION FOR CLUSTERING ANALYSIS OF EPIDEMIOLOGICAL DATA Jingyuan Zhang A thesis submitted in fulfilment of the requirements for the degree of Doctor of Philosophy College of ... major research objectives: the clustering analysis of epidemiological data and the geospatial visualisation of the results of the clustering analysis SOM, FCM and k-means, the three commonly used ... clustering analysis and the geospatial visualisation became the integral parts of the user interactive application for geospatial visualisation of the clustering analysis of epidemiological
Ngày tải lên: 04/12/2015, 14:00
QuEChERS A Mini-Multiresidue Method for the Analysis of Pesticide Residues in Low-Fat Products
... lost The extent of losses depends on the amount of lipids in the sample as well as on the polarity of the analytes with the most non-polar ones showing the highest losses In the presence of elevated ... for the Analysis of Pesticides Page of 12 QuEChERS A Mini-Multiresidue Method for the Analysis of Pesticide Residues in Low-Fat Products Aim and Scope This manuscript describes a method for the ... employ the internal standard at the end of the procedure (to an aliquot of the final extract) assuming the volume of the organic phase as being exactly 10 mL It should be furthermore noted that the
Ngày tải lên: 06/10/2016, 09:38
Birkhäuser boston daniel h greene donald e knuth mathematics for the analysis of algorithms
... science at Stanford University on the analysis of algorithms The course presents examples of the major paradigms used in the precise analysis of algorithms, emphasizing some of the more difficult ... reader is familiar with the fundamentals of complex variable theory and combinatorial analysis Winter 1980 was the fourth offering of Analysis of Algorithms, and credit is due to the previous teachers ... of the more difficult techniques Much of the material is drawn from the starred sections of The Art of Computer Programming, Volume [Knuth III] Analysis of algorithms, as a discipline, relies
Ngày tải lên: 18/04/2017, 12:21
Freeze-drying: An alternative method for the analysis of volatile organic compounds in the headspace of urine samples using solid phase micro-extraction coupled to gas chromatography - mass
... we compared the performance of sample preparation methods for the SPME-GC-MS analysis of urine samples To the best of our knowledge, this is the first study evaluating the potential of freeze-dry ... concentration of compounds in the headspace of the urine samples by increasing the ionic strength of these samples, which result in a richer profile of VOCs detected by GC-MS [11] Although the addition of ... freeze-dried, with the addition of 1 ml of saturated NaCl solution (salt), with the addition of 1 ml of 5M HCl solution (acid) or with the addition of ml of 5M NaOH solution (base) The results obtained
Ngày tải lên: 29/05/2020, 13:33
Application of dosimetry tools for the assessment of e-cigarette aerosol and cigarette smoke generated on two different in vitro exposure systems
... for the CFPs The acceptance criteria for the accuracy of the calibration curve was 100 ± 20%, the LOD was determined from standard deviation values of the signal to noise ratio of the calibration ... characterisation of the generated aerosol is required (at the point of generation and at the point of exposure) to enable comparisons before conclusions can be made from the associated biological responses There ... aerosols On the RM20S, nicotine ranged 2.5–16.8 ng/cm2/puff for the cigarette and 1.2–5.6 ng/cm2/ puff for the e-cigarette On the VC10, nicotine concentration ranged 10.0–93.9 ng/cm2/puff for the cigarette
Ngày tải lên: 29/05/2020, 14:37
mathematics for the analysis of algorithms (3rd ed ) greene knuth 2007 11 05 Cấu trúc dữ liệu và giải thuật
... science at Stanford University on the analysis of algorithms The course presents examples of the major paradigms used in the precise analysis of algorithms, emphasizing some of the more difficult ... reader is familiar with the fundamentals of complex variable theory and combinatorial analysis Winter 1980 was the fourth offering of Analysis of Algorithms, and credit is due to the previous teachers ... of the more difficult techniques Much of the material is drawn from the starred sections of The Art of Computer Programming, Volume [Knuth III] Analysis of algorithms, as a discipline, relies
Ngày tải lên: 29/08/2020, 18:31
An approach to improving the analysis of literature data in Chinese through an improved use of citespace
... analyzed the literature data in Chinese in the field of “teacher professional development” The CSSCI database was chosen as the main data source, where the CNKI database was selected as the supplement ... functionality of these tools, Citespace, VOSViewer, and Sci2 particularly emphasize on the literature data analysis, the analysis of data from citation indexes, and social network analysis, while ... construct the largest region in the middle of the figure, while Topics 4, 6, and are in three other regions with more distance The areas of the circles are proportional to the relative prevalence of the
Ngày tải lên: 27/09/2020, 15:02
Tools for Storm Analysis Using Multiple Data Sets
... case of three dimensional (3-D) gridded data In the case of atmospheric data, the ability to visualize the distribution of data in space (3-D) and time is quiet useful The wind is an example of ... Corporation for Atmospheric Research's UNIDATA However, the data sets currently available with THREDDS are still somewhat limited For this reason, the data used are from a variety of sources including the ... (GOES-12) Radar data are based on a national composite from individual WSR-88D radars across the U.S produced at Unidata Analysis of cloud clusters The analysis of cloud systems is based on the automated
Ngày tải lên: 18/10/2022, 07:48
a conceptual framework for the analysis of the effect of institutions on biofuel supply chains
... estimate for the variable C in the time t À actual value of the variable C from the time t À updated estimate of the variable C for the time t fixed cost of the refinery operated by the biofuel ... producer price of the biofuel producer j, [euro/l] expected rapeseed price, [euro/t] profit margin for the biofuel producer j profit margin for the distributor k perception of the biodiesel market ... chain on the performance of the system However, apart from the work of Happe et al., these studies did not analyze the effect of institutions on (parts of) biofuel supply chains development The remainder
Ngày tải lên: 08/11/2022, 14:57
recommendations for the analysis of individually randomised controlled trials with clustering in one arm a case of continuous outcomes
... training or even enthusiasm of the health professional delivering it This may then lead to a potential clustering of the outcomes for patients treated by the same health professional, but similar ... controlled trial where the treatment is delivered by a health professional it seems likely that the effectiveness of the treatment, independent of any treatment effect, could depend on the skill, training ... to the analysis of outcomes from an individually randomised controlled trial with clustering in one arm are identified in the literature Some of these methods are applied to four case studies of
Ngày tải lên: 04/12/2022, 16:04
recent advances and uses of monolithic columns for the analysis of residues and contaminants in food
... particle size, the distribution and the quality of the packing of the particles within the column determine the column quality In the case of packed columns, silica microspheres are the most used ... Very few examples of the application of these devices in the analysis of food can be found in the literature of the last five years, basically due to the complex characteristics of edible matrices ... access the active adsorption sites Large flow pores are responsible for the permeability of the monolith, and they allow LC separations at low pressures The inner pores of the particles in the packed
Ngày tải lên: 04/12/2022, 16:07
The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotides
... for the Wss_H, 50–60% for the Yss_H and 80–95% for the Ypk_H column Values for the small ODNs were 20–90% for the Wss_H, 30–40% for the Yss_H and 70–80% for the Ypk_H column These results demonstrate ... were considered and the impact of the UV flow cell was also highlighted The last part of the study deals with the extension of our observations with the analysis of a wide range of unmodified and ... considerations about flow cell materials The authors also wish to thank Waters Corporation (Milford, MA, USA) for the loan of the Acquity Premier system and for the gift of the Waters columns used in this
Ngày tải lên: 20/12/2022, 21:33
Recycling gradient-elution liquid chromatography for the analysis of chemical-composition distributions of polymers
... columns, because of the smaller particle size (2-μm vs 5-μm) and the absence of pores Additionally, irrespective of the column used, the shape of the peak depends on the molecular weight of the analyte ... temperature of 60 ºC Conclusion CRediT authorship contribution statement In this work the use of LC LC for the analysis of the CCD of copolymers is introduced and demonstrated The entirety of the gradient ... LC analysis of PS1 on the non-porous column was ended after the 10th cycle Fractions of the effluent were collected and subsequently measured with SEC The results 3.2 LC LC for the analysis of
Ngày tải lên: 20/12/2022, 21:34
An investigation into the use of gaussian processes for the analysis of microarray data
... the data in term of its distribution The value of the score is high if the two means of the classes are very different and the data of each class are crowded near the mean of the data Fisher Score ... method, i.e the outputs of the training examples are known and the purpose is to predict the output of new example In most of the cases, the outputs are either of two classes Hence, the task is ... encouraging results Except for the Leukaemia dataset, the results of the other three datasets show that the methodology perform competitively, compared with the results of Shevade and Keerthi (2002)...
Ngày tải lên: 28/09/2015, 13:38
Tài liệu Báo cáo khoa học: A systems biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana doc
... assessment of the trajectory of interconversion rates as a function of time of cold exposure, (b) comparison of the magnitudes of the various interconversion rates, and (c) lineup of the accessions ... photosynthesis, gas exchange of plants was measured by infrared gas analysis Measurements were performed during the first h 508 of the light phase, representing the time period of photosynthetic ... terms of the absolute values but also in the progression of the acclimation process This is an important outcome, as it allows estimation of the impact of different metabolic responses on the improvement...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... systems is therefore essential to prove the utility of the oocyte system and the validity of correlations based on the characterization of oocyte-expressed subunit combinations Nevertheless, the activity ... tissues The analysis of the DNA of different Conus species has already revealed a large number of a-conotoxin sequences [45] and the identification of further specific nAChR ligands is likely The advantage ... nanouseful information on the binding mode of a-conotoxins molar affinity (EC50 0.5–8 nM) and high selectivity for [53,58] and the activation states of the nAChR At the Table Comparison of a common...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo lâm nghiệp: "of morphological characters and molecular markers for the analysis of hybridization in sessile and pedunculate oak" pps
... Morphological analysis In the second case of the figure, the heterozygote deficit (f) must be considered The frequency of the phenotype A+ is the sum of the frequency of the genotype P : +/+ All of the ... means of the comparison of the RAPD marker frequencies of a subsampling of these progenies and of the adult population Analysis of the morphological characters MATERIALS AND METHODS Sampling The ... classified in the space of the other species over the analyses Molecular analyses The allele frequencies of the RAPD loci in the adult trees of the stand, calculated according to the two hypotheses:...
Ngày tải lên: 08/08/2014, 18:21
Báo cáo y học: "In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage" pptx
... established the modified, present form of the model, performed the real-time PCR, the immunohistochemistry and the respective data analyses and wrote the manuscript D Pohlers performed some of the experiments ... validity of the new model for the analysis of the mechanisms of cartilage destruction by SFB Both MMP-1, capable of cleaving intact collagen [44], and MMP-3, responsible for the cleavage of other extracellular ... higher amount of damage than the respective monocultures Collagen synthesis In view of an amplification of the potential net loss of collagen from the cartilage matrix, the synthesis of collagen...
Ngày tải lên: 09/08/2014, 01:22