... drugs, and mortality during treatment Initial presenting symptoms about which patients complained, and highest body temperature measured during initial presentation were included A body axillary ... of TB in the elderly A positive sputum AFB smear was obtained in 57.1% of elderly and in 57.5 % of young TB patients, and a positive AFB culture was obtained in 70.6% of the elderly and in 74.4% ... dormant lesions in TB These include insulin-dependent diabetes mellitus, poor nutrition, long-term corticosteroid therapy, other debilitating diseases, smoking, alcohol abuse, and waning cellmediated...
Ngày tải lên: 15/03/2014, 03:20
... polymorphic genes coding for cytokines or for cytokine receptors have been investigated in a case control study including a group of 40 Iranian PTB patients and 40 healthy individuals 126 IJI ... tuberculosis in Gambian patients may be partly determined by a region in the IL-1 gene cluster on chromosome (6) TGF-¾ codon 10 polymorphism was investigated in 110 healthy control and 101 tuberculosis patients ... cluster increases and T allele at codon 10 of TGF-¾ decreases in PTB patients Key words: Cytokine, PCR-SSP, Polymorphism, Tuberculosis INTRODUCTION A recent study by Hussain et al using a diluted...
Ngày tải lên: 22/03/2014, 18:20
báo cáo hóa học:" Validation of a HLA-A2 tetramer flow cytometric method, IFNgamma real time RT-PCR, and IFNgamma ELISPOT for detection of immunologic response to gp100 and MelanA/MART-1 in melanoma patients" doc
... positive cells in combination with the high inter-assay variability that is expected in flow cytometric methods This finding supported our clinical testing regimen; all longitudinal frozen PBMC ... analyte in biological matrix (matrix effect) is defined as the direct or indirect alteration or interference in response due to the presence of unintended analytes or other interfering substances in ... (in a single assay) Intra assay precision is determined by % CV (coefficient of variation) as (SD/ Mean) × 100 tested multiple times by one analyst in a single assay Inter assay precision (Intermediate...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học: " A case study of new assessment and training of unilateral spatial neglect in stroke patients: effect of visual image transformation and visual stimulation by using a head mounted display system (HMD)" doc
... difficulties when talking or communicating with others? neglect the left/right side of personal space? Show difficulties in eating? Show difficulties in grooming (self-care, washing, bathing, etc.)? Show ... activities of daily living Cyberpsychol Behav 2003, 6(4):383-388 Prothero JD: The treatment of akinesia using virtual images In Master's the-sis Industrial Engineering, University of Washington; 1993 Tanaka ... potential to enhance a human performance testing and training environment [25] VR has been investigated in a few studies using devices for augmentation of visual information For example, there is one...
Ngày tải lên: 19/06/2014, 08:20
Báo cáo hóa học: " Septic AKI in ICU patients. diagnosis, pathophysiology, and treatment type, dosing, and timing: a comprehensive review of recent and future developments" doc
... an apoptotic-inflammatory AKI, the administration of caspase inhibitors (CI) gains increasing interest Indeed, CI ameliorate ischemia-reperfusion injury in different organs, including the kidneys ... dysfunction in the ICU remains elusive [17] Serum creatinine concentrations and creatinine clearance are unreliable indicators for acute and abrupt changes in kidney function [27] Serum creatinine only ... Anticoagulation remains the topic of continuous development and research, in particular since the introduction of citrate and upcoming dedicated machines Unfractionated heparin (UFH) remains the most...
Ngày tải lên: 21/06/2014, 01:20
báo cáo khoa học: "The impact of surgical outcome after pancreaticoduodenectomy in elderly patients" doc
... performed in group A included Cholangiocarcinoma in 15 (48.4%) patients, Pancreatic adenocarcinoma in (25.8%), Ampullary carcinoma in (16.1%), Intraductal papillary mucinous neoplasm in (6.5%), ... http://www.wjso.com/content/9/1/102 included Pancreatic adenocarcinoma in 31 (46.3%) patients, Cholangiocarcinoma in 22 (32.8%), Intraductal papillary mucinous neoplasm in (6.0%), Ampullary carcinoma in (4.5%), Duodenal carcinoma ... emptying, liver abscess, wound infection, intraabdominal bleeding, respiratory insufficiency, intraabdominal collection, sepsis, bile leakage, or gastrointestinal bleeding There are summarized in...
Ngày tải lên: 09/08/2014, 02:21
Báo cáo khoa học: "The relationship among acute-phase response proteins, cytokines and hormones in cachectic patients with colon cancer" doc
... [23] Ghrelin participates directly in hypothalamic regulation of nutrition, it causes weight gain by reducing food utilization, increasing food intake, and inhibiting leptininduced feeding reduction ... loss and levels of pro-inflammatory cytokines, cytokins, APRP, adiponectin, ghrelin and leptin leves have not been explained yet We suggested that adiponectin, ghrelin and leptin are tightly regulated ... active ghrelin in cancer related cachexia have been reported in cohorts of mainly male lung cancer patients [26] In our study, we report elevated ghrelin levels in a cohort of colon cancer patients...
Ngày tải lên: 09/08/2014, 03:22
Báo cáo y học: "A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis" doc
... and breast cancer) in patients with RA in the recent published literature In particular, this review focused on observational studies comparing the incidence of malignancy in patients with RA versus ... trends reported in the individual studies This pattern included a clear increase in risks of lung cancer and lymphoma, both Hodgkin and non-Hodgkin, and a potential decrease in risks of colorectal ... consistent findings among the studies included in this metaanalysis where patients were taking diverse medications are consistent with the recent suggestion that it is the underlying inflammation...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: " Characteristics of CD8+ T cell subsets in Chinese patients with chronic HIV infection during initial ART" doc
... subsets during early period of ART In this study we investigated the dynamic changes not only in CD8+ cell subsets, but also in their activation and proliferation subsets in Chinese HIV/AIDS patients ... during initial ART are complex Almost all of the CD8+ cell subsets declined in activation levels during initial ART However, the trends of proliferation levels in different CD8+ subsets were inconsistent ... participated in the data analysis HW supervised and coordinated the study All authors have read and approved the final manuscript Competing interests The authors declare that they have no competing interests...
Ngày tải lên: 10/08/2014, 05:22
Báo cáo y học: " Partial anomalous pulmonary venous return and atrial septal defect in adult patients detected with 128-slice multidetector computed tomography." doc
... techniques have gained increasing importance in the non-invasive assessment of vascular pathologies of the chest In our patients, the diagnosis was established with certainty using contrast-enhanced ... of the heart documented with thorax x-ray The left upper lobe vein drains into the brachiocephalic vein (a-b) The right upper lobe vein drains into the superior vena cava (c) Veins of both lower ... Helsinki and HUS Radiology (Medical Imaging Center), Haartmaninkatu 4, Helsinki, 00029 HUS, Finland Department of Cardiology, Helsinki University Central Hospital, Page of Haartmaninkatu 4, Helsinki,...
Ngày tải lên: 10/08/2014, 09:22
báo cáo khoa học: "Effects of plasma concentrations of 5-fluorouracil on long-term survival after treatment with a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma" doc
... Association of clinical response with overall survival in Japanese patients with esophageal squamous cell carcinoma Line: patients with a complete response (CR, N = 23), dotted line: patients not ... Discussion Originally, 5-FU was administered alone as a bolus, but more recently, it is being administered with biomodulating agents and/or through continuous infusion [11,33] Because of the preclinical ... optimization by pharmacokinetic monitoring in 152 patients J Clin Oncol 1998, 16:1470-1478 Gamelin EC, Danquechin-Dorval EM, Dumesnil YF, Maillart PJ, Goudier MJ, Burtin PC, Delva RG, Lortholary...
Ngày tải lên: 10/08/2014, 10:21
Báo cáo khoa hoc:" Prospective Epidemiological Observations on the Course of the Disease in Fibromyalgia Patients" doc
... scale ratings from 0–10 provide more specific information about the patients' pain-induced functional limitations (Table 3): Pattern of pain at time point T0 In their pain history 4.2% of the patients ... reported flare-ups with pain-free intervals 14.5% of the patients gave no information about their pain pattern Factors influencing the pain and activity factors at T0 77.1% of the patients declared no ... observation period, in 48 patients with FM It was hoped that the findings might assist in identifying potentially successful treatment strategies that would be worthy of closer investigation in further...
Ngày tải lên: 11/08/2014, 08:20
Báo cáo y học: " Failure to detect Xenotropic murine leukaemia virus-related virus in Chinese patients with chronic fatigue syndrome" doc
... C-variant pac site is indicated by boldface type The broken line indicates the internal control sequences inserted in the CIC FAM: 6-carboxyfluorescein; HEX: 6-carboxyhexachlorofluorescein; BHQ: Black ... from Chinese patients with CFS The virus was not detected in any of our study subjects; these results not support an association between XMRV and CFS in Chinese Our findings appeared to be inconsistent ... primers Gag-1S and Gag-2A; the internal probe-binding sequences were introduced into fragment D Fragment CIC was obtained by a second overlapping PCR using primers Gag-1S and HCV-A to amplify from...
Ngày tải lên: 12/08/2014, 01:21
báo cáo khoa học:" Cross-cultural development of an item list for computer-adaptive testing of fatigue in oncological patients" doc
... outcome assessment including CAT administration has been given increasing attention within the EORTC Quality of Life group and software for CAT administration is being developed in parallel with ... towards single items Recommendations for patient interviews in the EORTC QLG guidelines for developing questionnaire modules were followed [25] Comments on the following issues were not included in ... pre-testing in cancer patients • Construction of an item list for international field testing Methods An overview on the EORTC CAT development strategy is given by Petersen et al [22] In the main,...
Ngày tải lên: 12/08/2014, 01:22
Báo cáo y học: " Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients" doc
... characterization of novel neutralizing epitopes in the receptor-binding domain of SARS-CoV spike protein: revealing the critical antigenic determinants in inactivated SARS-CoV vaccine Vaccine 2006, 24:5498-5508 ... KY, et al: Intranasal vaccination of recombinant adeno-associated virus encoding receptor-binding domain of severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein induces strong ... and Peking Union Medical College, Beijing 100730, China 2Peking Union Medical college Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China 3Lindsley...
Ngày tải lên: 12/08/2014, 02:20
Báo cáo y học: "High frequency of SEN virus infection in thalassemic patients and healthy blood donors in Iran" doc
... positive and individuals with liver disease [12,17,18] Ninety-eight percent of SENV infection in thalassemic patients is similar to the results obtained in Taiwan (90%) but in healthy individuals ... et al findings (2002) [12] Considering the reports of the replication of the virus in liver cells and the failure of manifesting clinical signs in infections such as cytomegalovirus, Epstein-Barr, ... 75% of SENV infection reported in Japan by Yoshida et al (2002) [16] Wide ranges of infection is reported in intravenous drug users, hemophilic and thalassemic patients, patients on maintenance...
Ngày tải lên: 12/08/2014, 04:21
Báo cáo y học: "Effectiveness of adalimumab in treating patients with ankylosing spondylitis associated with enthesitis and peripheral arthriti" doc
... as indicated by changes in MASES, and in inflammation across all examined entheses, including the plantar fascia Our results are consistent with results of a previous RCT of adalimumab in 315 patients ... M, Listing J, Sieper J: Comparison of the Bath Ankylosing Spondylitis Disease Activity Index and the modified version of the index in assessing disease activity in patients with ankylosing spondylitis ... fascia was reported for 173 patients, including 19 patients without enthesitis in MASES The distribution of enthesitis sites at baseline is shown in Figure Of the 281 (22.5%) patients with peripheral...
Ngày tải lên: 12/08/2014, 12:20
Báo cáo y học: " Adverse health consequences in COPD patients with rapid decline in FEV1 - evidence from the UPLIFT trial" doc
... exacerbation was shorter with increasing rate of decline in FEV quartiles, although results were somewhat inconsistent, especially for patients in the third quartile in the control group (Table ... rate of decline in the SGRQ total score increased linearly with each quartile increase in the post-bronchodilator decline in FEV1 (Figure 3) The range was from an improvement over time in Q1 (control ... appeared to be least impaired in those with the most rapid loss in FEV1 In longitudinal analyses, the patterns associated with quartiles of increasing rate of decline in FEV1 indicated a relationship...
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: " Glucocorticoid receptor gene polymorphisms associated with progression of lung disease in young patients with cystic fibrosis" doc
... sensitivity in a tissue-specific manner As the inflammatory process in CF is dominated by a neutrophil influx in the airways, our present findings reporting that CF patients carrying the BclI ... and OT have been involved in the interpretation of the data AH-C has been involved in collecting the patients DNA and the phenotypical data BF and JF have been involved in revisiting the manuscript ... significantly from the HardyWeinberg equilibrium indicating no bias in sampling in Table 2: Genotype frequencies and p-value for Hardy-Weinberg equilibrium (HWE) in the cystic fibrosis patients The genotype...
Ngày tải lên: 12/08/2014, 15:21
Báo cáo y học: "Validating English- and Spanish-language patient-reported outcome measures in underserved patients with rheumatic disease" doc
... Gelatin or Certo in grape juice 19 Ginger 20 Glucosamine Figure Final Inventory of Complementary and Alternative Medicine Practices sentences, redefining words with concrete examples, revising ... [13] included the following: 1) What does the term pain mean to you?; 2) What does no pain mean to you?; 3)What you think of when you think of the worst pain?; 4) Pain question: If is “no pain” ... duration from 46 minutes to hours, 10 minutes Conventional interviews using the same instrument were from 30 to 60 minutes in duration Updating the questionnaire was undertaken using an iterative...
Ngày tải lên: 12/08/2014, 15:22