time zone function in php
Báo cáo y học: " High blood pressure, antihypertensive medication and lung function in a general adult population"
... treat-ment and lung function in further prospective studies.ConclusionsOur findings are in line with previous observations show-ing an inverse association between blood pressure andlung function. Furthermore, ... effects onlung function or respiratory symptoms [13,14]. However,these studies investigated the potential effect of BBLintake on lung function mainly in patients with alreadyexisting pulmonary ... allowsonly statements about a single point in time and does notallow evaluating the effect of long-standing high bloodpressure. Another explanation for this lung function decrement could be that...
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A methodology for validation of integrated systems models with an application to coastal-zone management in south-west sulawesi
... paradigm’ in Thomas Kuhn’s (Kuhn, 1970) point of view. In view of the above investigation, integration is tentatively interpreted as an act or a process of joining or combining something with ... something else. The integrated approach is a way of perceiving and solving problems by integrating information, scientific disciplines, tools, interests and other aspects in a systemic way in ... overcome the inherent large uncertainty in model and data. In the World Coast Conference, held in 1993, the following definition of integrated coastal zone management was given (WCC, 1993): ‘Integrated...
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How to maximize part-time students ’ involvement in English speaking lessons at Hai Phong Foreign Languages Centre
... Teachers talking time in speaking lessons’The information obtained from Figure 6 indicates that teachers always take much time explaining in speaking lessons (70%). Only a small minority (10%) ... mother-tongued inference have bad influence on their involvement in English speaking lessons.1.4. Teachers difficulties in teaching speaking in speaking lessons’The result from the survey indicates ... difficulties in speaking lessons‘As shown in Figure 5, 18% of the participants think that finding ideas for the given topic is one of difficulties deterring their involvement in speaking lessons,...
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Tài liệu White Matter Changes Compromise Prefrontal Cortex Function in Healthy Elderly Individuals docx
... Prefrontal cortex andepisodic memory: Integrating findings fromneuropscyhology and functional brain imaging. In T. B.Amanda Parker & E. Wilding (Eds.), Memory encodingand retrieval: A cognitive ... spaced control pointsenables locally independent warps to be constructed in small subvolumes defined by cubes having controlpoints as vertices. These result in a matching of fineanatomical details. ... determine the regional dorsal PFCWMH volume for each individual.fMRI Data Preprocessing andSpatial NormalizationFunctional imaging data were realigned in SPM99and spatially normalized using in- house,...
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Tài liệu Báo cáo khoa học: SREBPs: SREBP function in glia–neuron interactions pdf
... FEBSsion of SREBP-1 in the brain does increase in miceduring aging [39], a phenomenon also observed in theperipheral nerve [3]. The meaning of this aging-relatedincrease in SREBP-1 in both the PNS ... myelin protein-22, myelin asso-ciated glycoprotein (MAG) and myelin basic protein,but no myelin-specific lipids. Nevertheless, whereas allmajor lipid classes are present in myelin, as in othermembranes, ... depletionof Lpin1 function in Schwann cells only is sufficient toinduce a demyelinating phenotype [23]. Whether lipidsfrom the epineurial compartment are implicated in functioning of axons and...
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Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc
... VH2-N)which we previously showed does contain an actin-binding domain (this actin-binding domain has not yetbeen mapped) [23]. We name the actin-binding domainthat we have identified VH2-C and VH2-N ... submodules in C-Vrp1p are required foractin-cytoskeleton polarization: a novel C-terminal actin-binding submod-ule (CABS) that contains a novel G-actin-binding domain, which we call averprolin homology ... domains are directlyimplicated in polarization of the yeast actin cytoskele-ton. The presence of the novel actin-binding VH2-Cdomain in C-Vrp1p364)817may explain why mutations in the N-terminal...
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Tài liệu Báo cáo khoa học: Metabolic gene switching in the murine female heart parallels enhanced mitochondrial respiratory function in response to oxidative stress pdf
... additional insights into thisinteresting question.Conclusions In summary, we have identified a novel metabolicgene switch (decrease in fatty acid utilization,increase in glucose utilization) in the ... 2007)doi:10.1111/j.1742-4658.2007.06051.xThe mechanisms underlying increased cardioprotection in younger femalemice are unclear. We hypothesized that serine-threonine protein kinase(protein kinase B; Akt) triggers a metabolic ... prosurvival serine-threonineprotein kinase, Akt (also known as protein kinase B)[2]. In agreement with this, elevated levels of activatedAkt in female hearts are linked to improved cardiaccell...
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Consultative document The internal audit function in banks pptx
... 2nd line Risk management function, compliance function and other monitoring functions 3rd line Internal audit function 56. Control failings by one line of defence should, in principle, ... 4 The internal audit function in banks 1. The internal audit function 8. The internal audit function plays a crucial role in the ongoing maintenance and assessment of a bank’s internal ... not interfere in its business decisions, it can be in a position to influence them by challenging management. Both the internal audit function and banking supervisors have an interest in the...
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The internal audit function in banks docx
... responsibility for maintaining the function s independence and objectivity. 14. The internal audit function should not be involved in designing, selecting, implementing or operating specific internal control ... directors remains ultimately responsible for these activities and for maintaining an internal audit function within the bank. Outsourcing of internal audit activities is further addressed in principle ... authority of the internal audit function within the bank in a manner that promotes an effective internal audit function as described in Principle 1. Principle 6: Every activity (including outsourced...
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Ecosystem Function in Heterogeneous Landscapes docx
... dynamicspace, complex feedbacks, or nonlinearities in responses. These componentsrequire a more dynamic consideration of interacting elements.Interacting ElementsAn interacting element approach is required ... new understanding about ecosystem function in time andspace.Looking AheadUnderstanding spatial heterogeneity has been referred to as “the final fron-tier” in other areas within ecology (e.g., ... book, providing synthetic views of theproblem and describing progress in developing overarching conceptualframeworks.ReferenceShugart, H.H. 1998. Terrestrial ecosystems in changing environments....
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Báo cáo khoa học: Amino acids Thr56 and Thr58 are not essential for elongation factor 2 function in yeast potx
... cystein, methionine and serine (Fig. 2).Mutants containing asparagine, aspartic acid, glycine,lysine or valine were nonfunctional (Fig. 2). Clonesexpressing eEF2 in which the adjacent threonine ... recombi-nation using LR clonase. The destination vector was trans-formed into strain YOR133w for confirming geneexpression, and into strain GB1 for functional analysis byplasmid shuffling. A copy ... were unable to functionally complementwild-type eEF2) were able to bind to ribosomes in cellsalso expressing wild-type eEF2 from one of theremaining eEF2 coding genes. Because binding ofeEF2...
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Báo cáo khoa học: Cholecystokinin rapidly stimulates CrkII function in vivo in rat pancreatic acini Formation of CrkII–protein complexes docx
... migrating band (lane 2),showing that it contains the more tyrosine phosphorylatedband of Crk. Pretreatment with tyrosine kinase inhibitoralone increased the intensity of the lower migrating ... phosphotyrosine-containing proteins such asp130Cas, paxillin or Cbl [10,12]. The first SH3 domain(N-terminal) of CrkII binds to guanine nucleotide exchangefactors such as C3G, which in turn activate ... Phosphotyrosine dependence of the CCK-8 induction of CrkIIelectrophoretic mobility shift in pancreatic acini. Rat pancreatic acinipreincubated for 2 h with the tyrosine kinase inhibitor, B44...
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Báo cáo Y học: Dystrobrevin requires a dystrophin-binding domain to function in Caenorhabditis elegans doc
... Dystrophin–dystrobrevin interactions in C. elegans (Eur. J. Biochem. 269) 1611Dystrobrevin requires a dystrophin-binding domain to function in Caenorhabditis elegansKarine Grisoni, Kathrin Gieseler ... reminiscent o f dystrophin (mdx )mutations [10].a-Dystrobrevin binds to dystrophin via a coiled-coiledmotif present in both proteins, and to the PDZ domaincontaining syntrophins [11,12]. Indirect ... dystrobrevinbinding to dystrophin and dystrobrevin function. Deletionsof the dystrobrevin protein w ere performed and the abilityof the mutated forms to bind t o dystrophin was tested both in vitro...
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Reproductive System Structure, Development and Function in Cephalopods with a New General Scale for Maturity Stages pot
... ofthisclass. In molluskswhichlaytheireggs in rigidcapsules, capsuleglandsandalbuminglandsare pres-ent in acomplexof pallial glands. Thesediffer in theiroriginand function (Chukchin,1984).Oviductalglands in octopussecrete ... ocean.Fecundityislow in squidinhabitingshelf areaswhere thebottomprovides a stable substrateforegglaying. In reef-livingSepioteuthis,only2 to 6 eggs arelaid in amucousstringwhichis hidden ... cells,particularlybytheirtransportandlocation in differentparts of the reproductivesystem up to the time of spawning.IntroductionAstructureof thereproductivesystem in cepha-lopodmales and femalesusuallyhas beenincluded in descriptionsof...
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Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx
... determinant behind its signaling capac-ity. The existence of a C-terminus domain (C-domain)emerged from a prediction of the 3D structure of asingle-chain heparanase enzyme [73]. In this proteinvariant, ... modularstructure [9]. Accumulating evidences indicate thatHSPGs act to inhibit cellular invasion by promotingtight cell–cell and cell–ECM interactions, and by main-taining the structural integrity and self-assembly ... theseemingly distinct protein domains observed in the 3Dmodel, namely the TIM-barrel and C-domain regions,mediate enzymatic and nonenzymatic functions of hep-aranase, respectively. Interestingly,...
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