... substantial in different cities of China Take Beijing and Shanghai as examples: people in North China such as Beijing are taller, larger than people in south and east China, and also food in north China ... The 1,524 individuals with T2DM finally included in this study were recruited from the outpatient department (OPD) of 15 general hospitals infour major cities of mainland China The findings derived ... outpatients in urban mainland China We found that complications are highly prevalent among urban mainland Chinese T2DM outpa- Page of tients Overall, more than half of the individuals included in this...
... pathogenesis of insulin resistance in humans using magneticresonance spectroscopy Obesity (Silver Spring) 2006;14 (Suppl 1): 34S–40S 31 Boden G Role of fatty acids in the pathogenesis of insulin resistance ... diseases and http://www.medsci.org Int J Med Sci 2010, cellular senescence (40-45) Source of reactive oxygen species in insulin secreting pancreatic β-cells and cells that are targets for insulin action ... leg ulcers contain localized oxidative stress (15) The recent finding revealed that insulin resistance is associated in humans with reduced intracellular antioxidant (11) Interestingly, antioxidants...
... CD in Finnish healthy population *** The ratio was similar to prevalence of CD in diabetic Czech population (4.3%) and higher than in healthy population (0.69%) Prevalence of CD in T1DM and ... gluten-free diet, so routine screening with measurement of quantitative serum IgA and antibody to human recombinant tissue transglutaminase (tTG) for CD is recommended in patients with T1DM (2) ... for IgAtTG Serum total IgA levels were within normal limits in these subjects Intestinal histopathology showed sub-total villous atrophy in the sibling (Marsh type 3c) Both parents refused endoscopic...
... Patients meeting criteria for inclusion and not meeting any exclusion criteria were invited to participate, and were included after accepting and signing an informed consent form Methods Visits in both ... subsequently trained in the procedure to be used in the study inthree sessions These covered the criteria for including/excluding patients, collecting variables, collecting biochemical/ Salinero-Fort ... Researchers in the experimental group received training in the PRECEDE model before patients were included in the study This specific training involved two steps: first they were instructed about...
... Suppl):S201-20 Borg G: Measuring Perceived Exertion and Pain In Borg's Perceived Exertion and Pain Scales Human Kinetics; 1998 Stewart AL, Ware JE Jr: Measuring Functioning and Well-being: The Medical Outcomes ... study planning, data analysis and drafting and revising the manuscript PO contributed to the study design, development of the research question and revising the manuscript and has given final approval ... becoming non-significant, with the addition of fitness in models and [Additional file 1] Discussion There are several important new findings in this cross-sectional study examining the influence...
... forms than in routine medical records This is in line with previous findings that medical record review, although broadly used for assessing ADEs, results in incomplete findings [11,58] Since there ... diaries; 4) administrative data, making use of diagnostic codes related to possible ADEs in administrative or claims data; 5) laboratory or clinical values indicating ADEs, including results of ... 1999 and January 2009 We searched for papers using MeSH headings, subheadings and free-text terms related to the following domains: (1) “adverse events”, and (2) “observational study design”, and...
... comprising insulin (NPH) twice daily and rapid-acting regular insulin three times daily pre-prandially, followed by a regimen of NPH and very-rapid acting insulin analogue (lispro) pre-prandially ... DM since the age of 11 For her diabetes, she was initially treated with insulin (Novolente) once and then twice daily for 35 years Subsequently, she was administered an intensified insulin regimen ... control in a way that has been virtually impossible to achieve with exogenous insulin [4] A thorough clinical and laboratory pre-transplantation work-up was then performed, including CT and MRI brain...
... defining illnesses In this perspective, anti-smoking campaigns may be crucial in making antiretroviral treatments more effective Competing interests The authors declare that they have no competing ... one seen, in HIVinfected persons, for smoking-related cancers Our group has recently shown, in Italian AIDS cases, a 4-fold higher risk in men and a 6-fold higher risk in women of developing lung ... the incidence of type diabetes mellitus in HIV-infected participants in the Swiss cohort study Clin Infect Dis 2007, 45:111-119 D:A:D Study Group: Use of nucleoside reverse transcriptase inhibitors...
... blood loss and transfusions, reduced infection and hospitalizations, and avoidance of visible scarring Disadvantages include difficulty in exposing the atrium, ventricle and mitral valves, increased ... improvement of clinical data, the patient was able to walk without any complaints, indicating NYHA classification of 1/4 Postoperative infectious signs were not recognized (Figure 1a and 1b), and the ... Valve, 27 mm) and tricuspid annuloplasty with a prosthetic ring (Duran Ancore Annuloplasty Band, 27 mm) were performed, and perioperative prophylactic intravenous vancomycin (1 g) was administered...
... 1985, 72:1-6 Bell-Krotoski JS, Weinstein S, Weinstein C: Testing sensibility, including touch-pressure, two point discrimination, point localization and vibration J Hand Ther 1993, 6:114 Dellon AL: ... all data in the study VBN carried out the clinical studies and participated in drafting the manuscript Both MM and PR conceived of the study and participated in its design and coordination All ... was undertaken in the nineteenth century by Vierodt [6] and Weber [7] Weber introduced the point localization test and the accompanying measures, two-point discrimination (TPD) and localization...
... stimulates increased metabolism in many tissues, leading to an increased demand for glucose [8] This in turn triggers stimulation of gluconeogenesis and lipolysis, leading to weight loss Overall, the increased ... disease Many clinicians would not have considered obtaining such a comprehensive work-up, including a radioactive iodine uptake, in this setting However, a thorough evaluation was essential in our patient, ... E, Tzanela M, Thalassinos N, Raptis SA: Insulin action in adipose tissue and muscle in hypothyroidism J Clin Endocrinol Metab 2006, 91:4930-4937 10 Crunkhorn S, Patti ME: Links between thyroid...
... since 1950 Searches were undertaken in MEDLINE and EMBASE, plus screening of reference lists in identified articles Potentially relevant reports, bulletins and guidelines were also screened, including ... Sauerwein H: Zidovudine/lamivudine contributes to insulin resistance within months of starting combination antiretroviral therapy AIDS 2008, 22(2):227-236 Magula NP, Mayosi BM: Cardiac involvement in ... giving plausible mechanisms as to why glucose control is impaired in TB patients[35] Inflammation caused by IL6 and TNFα whilst modulating a response to TB infection could cause an increase in insulin...
... by a decrease in hedonistic thoughts and an increase in sleeping problems, and to a lesser extent by an increase in feelings of panic and the feeling that things have been getting on top of oneself ... participated in statistical analysis and writing the manuscript; GN participated in data collection and preparation, and helped in writing the manuscript; VP participated in the design of the study, and ... helped in writing the manuscript; FP participated in the design of the study, and helped in writing the manuscript All the authors have read and approved the final manuscript Competing interests...
... administered into the coronary circulation of isolated rat hearts, and administered intravenously in canines with heart failure However, this insulinomimetic effect occurred within 30 minutes in ... for using insulin to mitigate myocardial injury in an acute setting have been limited Reasons for this limitation include problems associated with the acute use of intensive insulin therapy in patients ... tests in patients with coronary artery disease while decreasing post-test myocardial stunning, and reduce the need for insulin and inotropic support following coronary artery bypass grafting (94,...
... ‘GOLD STANDARD’ IN THE TREATMENT OF TYPE DIABETES MELLITUS METFORMIN AND BODY WEIGHT METFORMIN AND LIPID PROFILE While insulin secretagogues, thiazolidinediones and insulin itself promote increased ... combination of bedtime insulin and metformin was more effective in controlling glycemia, with a significantly less weight gain compared with bedtime insulin plus glibenclamide, bedtime insulin ... reducing insulin resistance, particularly in liver and skeletal muscle (7) The plasma insulin levels are unchanged or reduced (8) Metformin decreases intestinal absorption of glucose, and increases...
... Sharon and Jin Jing, for providing me guidance and help I also cherish all my colleagues in S7 02-09, Yingjiao, Mandy, Hua Pey, Regine and Wei Ting, and my unit mates, Sureerat, Nichanan and Poonna, ... condition of absence of insulin or insulin insufficiency a condition of the body not responding to insulin† a non-contagious disease a non-curable disease† Insulin: is a kind of hormone† controls ... brilliant mentorship and supervision, as well as his kindness, understanding and continuous encouragements since the beginning of my postgraduate life Even after he left Singapore for Australia,...
... a combination of resistance to insulin action and inadequate compensatory insulin secretion Although patients with this type of diabetes may have insulin levels that appear normal, insulin levels ... (CNS), including reducing food intake and body weight and interacting in predictable ways with other controllers of meal size (McGowan et al., 1990) On the other hand, its anabolic effects in peripheral ... STZ and alloxan, a marked reduction in insulin mRNA level was observed (Mulder et al., 1995) The insulin gene is present as a single copy in most species However, in rats, two nonallelic insulin...
... corroborating evidence for this earlier finding in Singaporean Chinese patients with T2DM Furthermore, nephrinuria was found to be associated with a decline in eGFR even in normoalbuminuric patients ... renal traits including eGFR and albuminuria in T2DM Chinese patients in Singapore These patients were from the Singapore Diabetes Cohort Study (SDCS) described in Methods 2.1.1 Aim 2: To investigate ... 1.5 T2DM and NPHS1 1.5.1 In vitro studies NPHS1 was expressed specifically both on the plasma membrane and the surface of insulin vesicles in the β-cells and promotes insulin secretion in response...
... zidovudine treatment New England Journal of Medicine 331: 1173–80 Corbitt, G (1999) HIV testing and screening Current practicalities and future possibilities In HIV and AIDS, Testing, Screening and ... depriving an at-risk group of advice which may be of particular value and relevance Voluntary testing can easily HIV inpregnancy slide into mandatory or near-mandatory testing Translating policy into ... understanding and information, and sometimes by coercion The ethics of anonymised unlinked screening for HIV inpregnancy With anonymized testing, there is a tension between the perceived interests...
... non-compliance inpregnancy of continuing their medication and risking the well-being of their future child, or abstaining from its use for the duration of the pregnancyand seriously risking their own ... during and after pregnancy The advice Medical advice about pregnancyand pregnancy- related behaviours begins before conception There are medical opinions on who should become pregnant, when and ... S Sherwin ∑ work, including unpaid housework (avoid exposure to dangerous chemicals, heavy lifting; reduce hours and stress; in certain circumstances, give up work altogether and remain conWned...