therapy with cytokines and anticytokines general considerations
Báo cáo khoa học: "Combination therapy with docetaxel and S-1 as a first-line treatment in patients with advanced or recurrent gastric cancer: a retrospective analysis" docx
... (S1 vs S-1 + CPT-11) revealed that OS with combination therapy did not significantly exceed that with mono -therapy [21] Other agents for use in combination with S-1, such as taxans, should also ... recurrent gastric cancer In this study, combination therapy with docetaxel and S-1 showed good clinical activity with acceptable toxicity in patients with advanced or recurrent gastric cancer The overall ... standard therapy for patients with advanced or recurrent gastric cancer In conclusion, our retrospective study demonstrated that the docetaxel and S-1 combination has good clinical activity with...
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Augmentation of neovascularization in murine hindlimb ischemia by combined therapy with simvastatin and bone marrow-derived mesenchymal stem cells transplantation pptx
... at 4°C for 15 minutes with occasional mixing MSCs labeled with DiI were washed times with PBS and then collected Laser Doppler blood perfusion analysis Isolation, expansion and labeling of MSCs ... contributions YL, DZ and YZ carried out the main experiment and drafted the manuscript FZ and DZ conceived of the study and designed the experiment GH helped to finish animal model and finished statistical ... combination therapy with high-dose simvastatin administration and MSCs transplantation could augment functional neovascularization in a mouse model of hind limb ischemia Materials and methods...
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Báo cáo sinh học: "Combined therapy with cyclophosphamide and DNA preparation inhibits the tumor growth in mice" docx
... treated with with the human growth (mean ± SEM) in mice shown below CP and Tumor DNA,10) Tumor growth (mean ± SEM) in mice treated with CP and human DNA, comparing the regimen shown below with the ... treated with with the human growth (mean ± SEM) in mice shown below CP and Tumor DNA,10) Tumor growth (mean ± SEM) in mice treated with CP and human DNA, comparing the regimen shown below with the ... Genetic Vaccines and Therapy 2009, 7:12 http://www.gvt-journal.com/content/7/1/12 Figure growth (mean ± SEM) in mice treated with CP and human DNA, comparing the regimen shown below with the control...
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counseling and therapy with clients who abuse alcohol or other drugs - c. glidden - tracey (lea, 2005)
... COUNSELING AND THERAPY WITH CLIENTS WHO ABUSE ALCOHOL OR OTHER DRUGS An Integrative Approach This page intentionally left blank COUNSELING AND THERAPY WITH CLIENTS WHO ABUSE ALCOHOL ... Doug Lamb, Don Mullison, David Reardon, Pamela Spearman, and Terry Tracey, all of whom have expanded my understanding of therapy in general and substance abuse issues in particular I gained much, ... and Mary Tracey, Fran Venegas, Tina and Brian Westmoreland, and, most especially, my parents, Ted and Dorie Glidden, and my mother-in-law, Ginny Tracey Finally, and most important, my work infinitely...
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Báo cáo sinh học: "Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma" pptx
... enzyme/prodrug therapy (GDEPT) or suicide gene therapy using viral vectors is an attractive alternative approach to cancer therapy, with the potential to give therapeutic ratios superior to standard chemoand ... (BUN) and creatine (Cr) using commercial kits (Sigma, MO, USA) For histological examination, some tissues were harvested, fixed with formalin and stained with hematoxylin and eosin mice without ... of T cells and NK cells and initiating Th1-type immune responses by activation of CD4+ and CD8+ cells [16] In the present study, we investigated a combined target suicide gene therapy and immunomodulating...
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Báo cáo sinh học: " Neopterin production and tryptophan degradation during 24-months therapy with interferon beta-1a in multiple sclerosis patients" docx
... with or without relapse and patients with or without NAbs At each time point, a Mann-Whitney test was performed to identify differences in biological markers and clinical measure between HD and ... biomarkers and the clinical variables In this study, we investigated the dynamic profile of neopterin and kyn/ trp ratio and its correlation with the clinical features in patients with RRMS treated with ... determined by measuring trp and kyn in 20 μl of a pool of 10 sera before and after adding 10 μl of mixture standard solutions of high and low concentration The recovery for trp and kyn was in the range...
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Báo cáo sinh học: "Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations" pdf
... M207 (synergistic) and SKMEL173 (antagonistic) are shown The black line represents the data obtained with vemurafenib treatment, the blue line with metformin, and the red line with combination ... metformin, from DM, HS and CN for the care of melanoma cell lines and cell viability studies and from BC-A for the optimization and conduct of cell viability, cell cycle, apoptosis and phosphoflow studies: ... lines are representative of different oncogenic events in melanoma and include 10 cell lines with a BRAF (BRAFV600E) and cell lines with an NRAS (NRASQ61L or NRASQ61K) mutation [16] M249-AR4, one...
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báo cáo hóa học: " Comparing a disease-specific and a generic health-related quality of life instrument in subjects with asthma from the general population" pot
... AQLQ and SF-36 domain scores graphically and by looking at skewness and kurtosis Since AQLQ and SF-36 scores were skewed towards high scores and not distributed normally, we calculated medians and ... the AQLQ domain scores were found between and 2, and and 7, respectively, and when the SF-36 domain scores were found between and 10, and 90 and 100, respectively For internal consistency reliability, ... between 25% and 75% of the forced vital capacity *p = 0.01 and p < 0.05 compared to groups A and B, respectively; †p = 0.01 and p < 0.05 compared to groups A and B, respectively; ‡p < 0.01 and p
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báo cáo hóa học:" Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma" doc
... enzyme/prodrug therapy (GDEPT) or suicide gene therapy using viral vectors is an attractive alternative approach to cancer therapy, with the potential to give therapeutic ratios superior to standard chemoand ... (BUN) and creatine (Cr) using commercial kits (Sigma, MO, USA) For histological examination, some tissues were harvested, fixed with formalin and stained with hematoxylin and eosin mice without ... of T cells and NK cells and initiating Th1-type immune responses by activation of CD4+ and CD8+ cells [16] In the present study, we investigated a combined target suicide gene therapy and immunomodulating...
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báo cáo hóa học:" Neopterin production and tryptophan degradation during 24-months therapy with interferon beta-1a in multiple sclerosis patients" pot
... with or without relapse and patients with or without NAbs At each time point, a Mann-Whitney test was performed to identify differences in biological markers and clinical measure between HD and ... biomarkers and the clinical variables In this study, we investigated the dynamic profile of neopterin and kyn/ trp ratio and its correlation with the clinical features in patients with RRMS treated with ... determined by measuring trp and kyn in 20 μl of a pool of 10 sera before and after adding 10 μl of mixture standard solutions of high and low concentration The recovery for trp and kyn was in the range...
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báo cáo hóa học:"Early initiation of antiretroviral therapy results in decreased morbidity and mortality among patients with TB and HIV" ppt
... study size is small and limited by non-contemporaneous treatment approaches, this study suggests that immediate treatment with antiretroviral therapy in patients with TB and advanced HIV markedly ... death The baseline demographic and clinical characteristics of subjects in Groups I and II are provided in Table The mean age in Group I and Group II was 33.3 ± 7.9 and 37.8 ± 6.3 respectively All ... proportion with extra-pulmonary TB Baseline resistance did not differ between the two groups The number of patients coinfected with the hepatitis C virus (HCV) was 38 and 15 in Group I and Group...
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báo cáo hóa học: " Improvement in health-related quality of life after therapy with omeprazole in patients with coronary artery disease and recurrent angina-like chest pain. A double-blind, placebo-controlled trial of the SF-36 survey" ppt
... consecutive outpatients with CAD-11 female (23%) and 37 male (77%)-diagnosed with recurrent stable angina-like chest pain refractory to standard anti-angina therapy and without indications for ... rabeprazole (1 × 20 mg) and a placebo on HRQL as measured by the SF-36 Health Survey in patients with cardiovascular disease requiring therapy with acetylosalicylic acid, both with and without gastrointestinal ... gastric and duodenal ulcer disease, Helicobacter pylori eradication, in the prevention of gastric and duodenal damage during therapy with non-steroidal antiinflammatory drugs, and in empirical therapy...
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Báo cáo hóa học: " Research Article Hybrid Steepest Descent Method with Variable Parameters for General Variational Inequalities Yanrong Yu and Rudong Chen" pptx
... Feasibility and Optimization and Their Applications (Haifa, 2000), D Butnariu, Y Censor, and S Reich, Eds., vol 8, pp 473–504, North-Holland, Amsterdam, The Netherlands, 2001 [12] H K Xu and T H ... K-constrained generalized pseudoinverse of A associated with θ (symbol AK,θ ) is defined as D(AK,θ ) = D(AK ), AK,θ (b) = x0 , and b ∈ D(AK,θ ), where 12 Journal of Inequalities and Applications ... Kinderlehrer and G Stampacchia, An Introduction to Variational Inequalities and Their Applications, vol 88 of Pure and Applied Mathematics, Academic Press, New York, NY, USA, 1980 [3] M A Noor, “General...
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Báo cáo hóa học: " APPROXIMATING ZERO POINTS OF ACCRETIVE OPERATORS WITH COMPACT DOMAINS IN GENERAL BANACH SPACES HIROMICHI MIYAKE AND WATARU TAKAHASHI " pdf
... H Miyake and W Takahashi 95 Let D be a subset of C and let P be a retraction of C onto D, that is, Px = x for each x ∈ D Then P is said to be sunny [16] if for each x ∈ C and t ≥ with Px + t(x ... retraction P of C onto D We know that if E is smooth and P is a retraction of C onto D, then P is sunny and nonexpansive if and only if for each x ∈ C and z ∈ D, x − Px,J(z − Px) ≤ (2.4) For more details, ... implies that z ∈ F(Jr ) = A−1 Let {Jtn x} and {Jsn x} be subsequences of {Jt x} such that {Jtn x} and {Jsn x} converge strongly to y and z as tn → ∞ and sn → ∞, respectively From z ∈ A−1 0, we...
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Báo cáo khoa học: "Studies of cocktail therapy with multiple cytokines for neoplasia or infectious disease of the dog" pps
... the glycine and arginine residues Canine IL-3 signal peptide shares 66.7% and 70.8% homology with bovine and ovine IL-3, but less than 50% with human IL-3 and no significant homology with rat IL-3 ... washed twice with phosphate-buffered saline (PBS) and plated to a concentration of × 106 cells per ml in RPMI 1640 (GIBCO, Grand Island, USA) supplemented with 10% fetal calf serum (FCS) and 50 µg/ ... obtained with LPS or ConA plus PMA stimulation with incubation times of 2h, 4h and 7h (data not shown) As expected from the design of the primers BamHIcaIL3-F and HindIIIcaIL3-R, a single band of...
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Báo cáo khoa học: "In vitro and in vivo gene therapy with CMV vector-mediated presumed dog b-nerve growth factor in pyridoxine-induced neuropathy dogs" pot
... the primers NGF-1F and NGF-1R and 400 bp with the primers NGF-2F and primer NGF-2R Overlapping PCR was performed to combine the PCR products of the partial dβ-NGF using NGF-1F and NGF-2R This overlap ... The phCMV vector and pcDNA2 were digested with Bgl II and EcoR I restriction enzymes, and purified following separation on a 1.5% agarose gel Ligation of the purified phCMV1 and pcDNA2 was performed ... positive control group and four dogs were in the experimental group with gene therapy All of the dogs were clinically judged to be in good health and neurologically normal, and had their own admission...
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Báo cáo y học: "Subcutaneous Immunoglobulin-G Replacement Therapy with Preparations Currently Available in the United States for Intravenous or Intramuscular Use: Reasons and Regimens" docx
... presenting with recurrent infections and failure to respond with, and/ or to maintain, protective antibody titres after immunization with polysaccharides from Haemophilus influenzae and/ or Streptococcus ... subcutaneously.6,7 Gardulf and colleagues8 and Berger9 have also reported that the frequency of serious and/ or systemic adverse effects is lower with subcutaneous administration than with IV administration ... included chills and rigours during IGIV infusions and/ or severe headaches, often with nausea and vomiting or other symptoms of migraine that occurred during IGIV infusion or within 48 hours of...
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báo cáo khoa học: "Selective intraarterial radionuclide therapy with Yttrium-90 (Y-90) microspheres for unresectable primary and metastatic liver tumors" potx
... Table H and EH disease rates of the R and NR groups No of patients (%) R NR H 30(69%) 11(31%) EH 13(31%) 24(69%) Table The mean and median survival times of the R and NR groups Means and Medians ... Van Hazel G, Hope M, Burton M, Moroz P, Anderson J, Gebski V: Randomised trial of SIR-Spheres plus chemotherapy vs chemotherapy alone for treating patients with liver metastases from primary large ... radioembolization with Y-90 microspheres-safety, efficacy and survival Radiol 2008, 248:507-515 Bujold A, Dawson LA: Stereotactic radiation therapy and selective internal radiation therapy for hepatocellular...
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báo cáo khoa học: "Correction: Selective intraarterial radionuclide therapy with Yttrium-90 (Y-90) microspheres for unresectable primary and metastatic liver tumors." pptx
... treatments with 90Y for liver metastasis or primary HCC between June 2008 and October 2010.“ References N Ozlem Kucuk, Cigdem SOYDAL, Seda Lacin et al Selective intraarterial radionuclide therapy with ... Abstract, Patients and method and Results sections The correct text is included below In the ‘Methods’ section of the Abstract, the first sentence should have read: “The clinical and follow-up data ... between June 2006 and October 2010 were evaluated retrospectively.” In The ‘Patients’ section of the Patients and Method, the first sentence should have read: “The clinical and follow-up data...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25