... combination therapy However, existing data support therapy of the patient with compensated cirrhosis Cirrhotic patients may tolerate therapy less well, given the propensity for thrombocytopenia and leucopenia, ... cytopenias The use of these agents is costly and has not been studied rigorously in a randomized controlled format to assess their value and impact on efficacy of therapy although they are now widely ... initial dose, with increases every two weeks toward standard target doses Duration of therapy was intended to be 24 weeks in genotypes and and 48 weeks in genotype infection Hematologic inclusion...
Ngày tải lên: 31/10/2012, 17:11
... effects on therapy patients, its unanticipated personal and professional consequences for therapists, and its extraordinary challenges to conventional clinical theories and methods In addition, Therapy ... grateful to my family – to my children, Hayley, Brigitte, and Tyler, and to my husband, Brinkley Messick – for lovingly standing by me and giving me the space to complete this project 12:24 P1: ... corporate boardrooms, community centers, and firehouses, and later, for a fee, in private offices Starting on 9/11 and continuing for months and years, thousands of therapists listened for countless...
Ngày tải lên: 15/03/2014, 01:20
Novel Gene Therapy Approaches Edited by Ming Wei and David Good pdf
... Gene Therapy 119 Koichi Miyake and Takashi Shimada VI Contents Chapter Replicating Retroviral Vectors for Gene Therapy of Solid Tumors 129 Matthias Renner and Juraj Hlavaty Chapter A Novel Therapy ... Communication in Cancer Gene Therapy 327 Mohamed Amessou and Mustapha Kandouz Chapter 14 Cancer Gene Therapy with Small Oligonucleotides 353 Onur Sakiragaoglu, David Good and Ming Q Wei Chapter 15 ... depletion on the pharma‐ cokinetics and gene delivery mediated by cationic lipid-DNA complexes Human Gene Therapy 1998;9(3) 315-323 [56] Tandia BM, Vandenbranden M, Wattiez R, Lakhdar Z, Ruysschaert...
Ngày tải lên: 23/03/2014, 14:20
Báo cáo hóa học: " Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits" pot
... extraction and CTL assays All the animals were housed and handled in accordance with the European guidelines no 86/609/CEE and 116/92 for the protection of laboratory experimental animals and laboratory ... integrated HPV-16 DNA, and green monkey kidney (Vero) cells were grown in DMEM supplemented with 10% CS and P/S Rabbit PBMCs were obtained from heparinised rabbit blood and used for CTLs and cytokine assays; ... 10% FCS, and P/S Rabbit skin fibroblasts were obtained with a 3-mm biopsy punch and immortalised with SV40 [40]; these were first grown in DMEM supplemented with 10% CS, 5% FCS, and P/S, and then...
Ngày tải lên: 18/06/2014, 16:20
Statin Therapy, LDL Cholesterol, C-Reactive Protein, and Coronary Artery Disease pot
... implications for understanding the pathogenesis of the progression of atherosclerosis and the mechanism of benefit of statin therapy The Pravastatin or Atorvastatin and Infection Therapy (PROVE IT) ... (C.O.); and Brigham and Women’s Hospital, Boston (P.G.) Address reprint requests to Dr Nissen at the Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, ... of atherogenic lipoproteins, CRP, and HDL cholesterol and the rate of progres- Table Baseline and Follow-up Values for Intravascular Ultrasonographic End Points and Change in Values from Baseline.*...
Ngày tải lên: 27/06/2014, 00:20
Báo cáo khoa học: " Carbon ion therapy for advanced sinonasal malignancies: feasibility and acute toxicity" pdf
... received mixed-beam radiotherapy consisting of IMRT either in step -and- shoot technique (22 pts) or tomotherapy (3 pts) and carbon ion boost Four patients received carbon ion therapy only Median total ... coverage • Parotid glands: mean dose to at least one gland below 26 Gy; alternatively at least 20 cc of the combined volume of both parotid glands to
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: "Intensity modulated radiation therapy (IMRT): differences in target volumes and improvement in clinically relevant doses to small bowel in rectal carcinoma" pps
... and 1.8-Gy daily fractions The intended targeted tissues included the gross tumor and nodal disease, which were contoured based on the CT simulation scan, mesorectum, and the internal iliac and ... reviewed and deemed clinically acceptable by both a gastrointestinal clinical physicist and radiation oncologist Plan evaluation and statistical tools Evaluated volumes included the PTV and relevant ... carried out the study conception and design and drafted the manuscript MBP performed treatment planning TMB and SB performed physics checks/plan evaluation Patient accrual and radiation field design...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: "Target splitting in radiation therapy for lung cancer: further developments and exemplary treatment plans" pps
... withdrawn and the primary tumor alone is treated to 79,2 Gy V20 right and left lung and V25 both lungs is 49%, 22% and 26%, respectively V50 for the heart is 2% Peripheral tumor located lateral and ... MLC coverage and/ or to allow the insertion of a motorized wedge, all combinations of possibly adjacent jaws (x1/x2, x1/y1, x1/y2, y1/x2 and y1/y2) have to be tested On a monthly basis and after ... lobe, 5,5 cm ∅; enlarged PET-positive hilar, subcarineal and bilateral mediastinal nodes A Scheme; position of junction plane and upper and lower borders, doses (Gy) B Treatment plan single fraction...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Group cognitive behavioural therapy for women with depression: pilot and feasibility study for a randomised controlled trial using mixed meth" pptx
... the design of the intervention and to help understand issues of acceptability and feasibility Interviews were conducted with all (75) participants at baseline and at and months exploring motivation ... (attending a group with other stressed women and being taught skills to cope better) helped participants and recruiters to understand and promote the groups The wide and inclusive criteria for the study ... scores) and high, low or no attendance at groups In addition, interviews with GPs and community staff were conducted and feedback collected from the facilitators during focus groups and on a...
Ngày tải lên: 11/08/2014, 15:22
Báo cáo y học: " Cognitive behaviour therapy in medicationtreated adults with ADHD and persistent Symptoms: A randomized controlled trial'''' doc
... Services, Landspitali - The National University Hospital of Iceland, Hringbraut, Reykjavik, Iceland 3Child- and Adolescent Psychiatry, Landspitali - The National University Hospital of Iceland, Dalbraut ... modified for adults and translated into Icelandic Magnusson et al [26] found that the K-SADS was reliable and valid and had strong Page of 10 correlation with self-reported and informant rated ... populations and settings and maximises programme integrity Thus the benefits of R&R2ADHD are multifaceted and the combination of psychopharmacological and CBT treatments may add to and improve...
Ngày tải lên: 11/08/2014, 15:22
Báo cáo khoa học: "Early goal-directed therapy after major surgery reduces complications and duration of hospital stay. A randomised, controlled trial [ISRCTN38797445]" ppt
... Mortality and morbidity) and APACHE II (Acute Physiology and Chronic Health Evaluation II) scores were calculated after admission to the ICU [15,16] Patients were followed up for 60 days Diagnosis and ... had been randomised to the GDT group and 60 patients to the control group The groups were well matched for age, sex, blood loss, type of surgery and anaesthetic technique (Table 1) and control ... involved in data analysis and drafting the manuscript and approved the final version All authors had full access to data and take responsibility for the integrity of the data and the accuracy of the...
Ngày tải lên: 12/08/2014, 23:20
Báo cáo y học: " Tight glucose control: should we move from intensive insulin therapy alone to modulation of insulin and nutritional inputs" pps
... be applied and to derive which benefits? Which is the best method to control glucose level intensive insulin therapy, and/ or limitation of nutritional intakes during acute phase, and/ or antidiabetic ... (SepNet): Intensive insulin therapy and pentastarch resuscitation in severe sepsis N Engl J Med 2008, 358:125-139 Merz TM, Finfer S: Pro/con debate: is intensive insulin therapy targeting tight blood ... Weinreb J, Hoo GW: Intensive insulin therapy in critical care: a review of 12 protocols Diabetes Care 2007, 30: 1005-1011 Pittas AG, Siegel RD, Lau J: Insulin therapy and in-hospital mortality in critically...
Ngày tải lên: 13/08/2014, 11:22
ESP coursebooks for physical therapy students at university of Medicine and Phamacy in Ho Chi Minh city An investigation
Ngày tải lên: 25/11/2014, 00:42
How to design and write web pages today
... collection of pages, any successful Web site will depend on the solid construction of individual pages, including page elements such as branding, text and media content, and navigation • “Problems and ... learn to read and write From the visual designs of your pages, to the structure of your pages, to the Web servers that deliver your pages to readers, the Web is nothing but language And those who ... professionals, and general readers write effectively for a range of audiences and purposes Some books in the series cover topics of wide interest, such as how to design and write Web pages and how to...
Ngày tải lên: 27/08/2012, 13:55
Báo cáo y học: "Oral Rehydration Therapy for Preoperative Fluid and Electrolyte Management"
... intravenous therapy [8−10] and has recently gained widespread acceptance and is now preferred in the United States and in European countries In the pilot study, we investigated the safety and effectiveness ... sodium, and urinary creatinine Vital signs were analyzed using the repeated-measures analysis of variance and the Dunnett test (two-sided at =0.05) Blood and urine values and FENa values before and ... intravenous therapy in terms of the effect on the supplementation of water, electrolytes, and carbohydrates [8, 9] We conclude that ORT is a safe and effective therapy for the preoperative fluid and...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: "Ozone Therapy and Hyperbaric Oxygen Treatment in Lung Injury in Septic Rats"
... animals had been fed standard rat chow and water ad libitum and housed in cages with controlled temperature and 12-hour light/dark cycle for at least week Experimental groups Antibiotherapy is an established ... clinical studies in animal models and human beings are needed to understand molecular elements, ligand and receptors, involved in the mode of action of ozone and HBO Finally, according to the ... plasma, lymph and urine; and immediately reacts with polyunsaturated fatty acids, antioxidants, reduced glutathione and albumin resulting in formation of lipid peroxidation products and H2O2 While...
Ngày tải lên: 25/10/2012, 11:18
Báo cáo y học: "Comparison between single antiplatelet therapy and combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with antiphospholipid syndrome"
... Med Sci 2010, with APS We therefore compared single antiplatelet therapy and a combination of antiplatelet and anticoagulation therapy for secondary prevention in ischemic stroke patients with ... with venous and arterial occlusive disease in multiple organs, miscarriages, and livedo reticularis Materials and Methods We focused on the secondary prevention of stroke with APS, and compared ... prevention of stroke with APS, and compared single antiplatelet therapy and a combination of antiplatelet and anticoagulation therapy in ischemic stroke patients with APS The subjects were 20...
Ngày tải lên: 26/10/2012, 09:48
Báo cáo y học: "Comparison of osteogenic potentials of human rat BMP4 and BMP6 gene therapy using [E1-] and [E1-,E2b-] adenoviral vectors"
... (Lanes 1, and 3), BstXI (Lanes 4, 5, and 6), and BglII plus EcoRV (Lanes 7, 8, and 9) M, 1-kb DNA ladder Lanes 1, 4, and 7, 293A cells; Lanes 2, 5, and 8, ADrBMP6 DNA; Lanes 3, 6, and 9, ADhBMP6 ... BMP4 and BMP6 cDNAs were amplified, cloned, sequenced, and identified Recombinant adenoviruses encoding rat BMP4 and BMP6 were constructed and compared with ADhBMP4 and ADhBMP6 in the in vitro and ... Eight AN rats and 20 SD rats were used for the study of BMP4, and 16 AN rats and 21 SD rats for the study of BMP6 Animal protocols were approved by the University of Virginia Animal Use and Research...
Ngày tải lên: 31/10/2012, 17:08