... stretching out the distribution to the right or pushing in the distribution to the left and it has no effect on the shape of the distribution In fact, a change in the scale parameter is the same ... Rate Exponentially decreasing Constant Increasing Linearly increasing Rapid increasing Very rapidly increasing The importance of the shape parameter to the Weibull distribution has been discussed ... focuses on the parameter estimation methods for the two-parameter Weibull distribution Unless otherwise indicated, the Weibull distribution in this thesis refers to the two-parameter Weibull distribution...
Ngày tải lên: 12/09/2015, 08:19
... domains or by specific phosphopeptides that bind to the SH2 domains The tandem SH2 domains bind to Tyr-627 and Tyr-659 simultaneously in a specific orientation, in which Tyr-627 binds to the ... ERK activation [28-30] The Gab1 polymorphism may affect the interaction with SHP-2 through the mechanism such as BTAM after H pylori infection, resulting in influencing the abnormal proliferation ... needed to confirm our finding This study, however, had 80% power to detect an absolute difference in the frequency of G/A+A/A, given 44% in the case and 56% in the control The PTPN11 polymorphism...
Ngày tải lên: 31/10/2012, 15:37
unit 1 - mai lan houng - with key
... is a making clothes b painting c washing dishes d mending chairs 19 My Dad is always willing to give a hand cleaning the house a of b with c about d in 20 most men , my father can cook ... happy READING PASSAGE 2: Read the following passage and choose the best answer a, b, c or d: In my family, my wife, Catherine , is the first person (6) up in the morning She’s great! Normally I ... employment by doing their share of cleaning and child care, the couples are usually happy in their marriages Where husbands expect their wives to all the housework as well as their jobs, there is frequently...
Ngày tải lên: 13/09/2013, 18:10
Activity 6.1: Organizing Use Cases and Usage Scenarios
... Consolidating Redundancies In this exercise, you will look at the existing groupings and remove any redundant information Use the list of uses cases generated in Exercises and to eliminate redundant use ... actors by using the list you generated in Activity 5.1 Do not eliminate redundancies at this point Actor Use case Activity 6.1: Organizing Use Cases and Usage Scenarios Exercise 2: Organizing Use ... Scenarios In this activity, you will analyze the activities within usage scenarios to determine if there are repeated processes that need to be rolled into a new use case ! Analyze the consolidated...
Ngày tải lên: 18/10/2013, 18:15
Tài liệu Advanced Linux Programming: 1-Advanced UNIX Programming with Linux pdf
... n Finding More Information emacs The Emacs text editor info The Info system itself Almost all the standard Linux programming tools (including ld, the linker; as, the assembler; and gprof, the ... typed in the following: int main () { printf (“Hello, world\n”); } If you press the Tab key on the line with the call to code to look like this: printf, Emacs will reformat your int main () { printf ... good reading for inquiring minds Don’t include them directly in your programs, though; always use the header files in /usr/include or as mentioned in the man page for the function you’re using 1.5.4...
Ngày tải lên: 21/01/2014, 07:20
tom m apostol calculus, vol 1 one-variable calculus with an introduction to linear algebra second edition volume 1 1967
... between the integral and the derivative The concept of the integral is defined first for step functions Since the integral of a step function is merely a finite sum, integration theory in this ... for testing the validity of theorems in set theory or for suggesting methods to prove them Of course, the proofs themselves must rely only on the definitions of the concepts and not on the diagrams ... reason the line is often called the real Zinc or the real axis, and it is customary to use the words real number and point interchangeably Thus we often speak of the point x rather than the point...
Ngày tải lên: 12/06/2014, 16:19
Báo cáo sinh học: "Detailed genetic analysis of hemagglutinin-neuraminidase glycoprotein gene in human parainfluenza virus type 1 isolates from patients with acute respiratory infection between 2002 and 2009 in Yamagata prefecture, Japa" docx
... this is the first report of these findings in HPIV1 The distribution of amino acids affects the structure of the HN coding region in HPIV1, and previous reports show that substitutions of amino acids ... the minor clusters in the trees The tree was constructed by neighbor-joining analysis with labeling of the branches showing at least 70% bootstrap support The representation of the strain was ... nucleotides in the second binding site of HN gene were observed among the present isolates The strains were classified into two major clusters in the phylogenetic tree by the NJ method Another phylogenetic...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo hóa học: " The product of the Herpes simplex virus 1 UL7 gene interacts with a mitochondrial protein, adenine nucleotide translocator 2" pot
... domains of the recombinant viruses Line 1, a linear representation of the YK304 genome The YK304 genome has bacmid (BAC) in the intergenic region between UL3 and UL4 Line 2, the genomic domain ... experiments, which reinforced the interaction between UL7 and the mitochondrial protein Together, these series of observations indicate that UL7 interacts with ANT2 in HSV-1-infected cells The biological ... up-regulated in proliferative cells, including several cancer cell lines, and induces apoptosis by interacting with many kinds of materials [21], including viral protein (Vpr of HIV-1 and pBI-F2 of influenza...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo sinh học: " Research Article Aλ3 λ1 , λ2 , Ω -Weighted Inequalities with Lipschitz r and BMO Norms" doc
... of Inequalities and Applications Choosing m s/ αλ3 r −1 s , then m < s < t Applying the weak reverse Holder inequality ¨ for the solutions of the nonhomogeneous A-harmonic equation, we obtain ... B ⊂ Ω We have completed the proof of Theorem 3.2 Now, we will prove the following weighted inequality between the BMO norm and the Lipschitz norm for Green’s operator Theorem 3.3 Let u ∈ Ls Ω, ... be a smooth form in a bounded domain Ω and let G be Green’s operator Then, there exists a constant C, independent of u, such that G u ,Ω ≤ C du s,Ω 2.8 Main Results and Proofs Theorem 3.1 Let...
Ngày tải lên: 21/06/2014, 17:20
PIC18F97J60 Family Data Sheet64/80/100-Pin, High-Performance, 1 Mbit Flash Microcontrollers with docx
... on the setting of the IDLEN bit The power-managed mode that is invoked with the SLEEP instruction is determined by the setting of the IDLEN bit at the time the instruction is executed If another ... providing the clock If neither of these bits is set, INTRC is clocking the device Note: 3.1.4 In the Run modes, clocks to both the core and peripherals are active The difference between these ... complete, the OSTS bit is set and the primary clock is providing the device clock The IDLEN and SCS bits are not affected by the switch The INTRC source will continue to run if either the WDT or the...
Ngày tải lên: 22/06/2014, 15:20
Báo cáo y học: "Selective serotonin reuptake inhibitor use associates with apathy among depressed elderly: a case-control study" potx
... atypical noradrenaline and dopamine reuptake inhibitor The SSRI's including in descending order of frequency of use: sertraline, paroxetine, fluoxetine, citalopram, and fluvoxamine ANOVAs revealed ... co-morbid or underlying axis III diseases and other medication use during the stay are indicated in Table Due to missing HAMD, the data related to the scale were available in 290 patients The number of ... assessing apathy were not included in the database Thus, the investigators retrieved some associated items from the GDS and the HAMD-21 for apathy evaluation From the GDS, the following items were used:...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Segregation of a M404V mutation of the p62/sequestosome 1 (p62/SQSTM1) gene with polyostotic Paget''''s disease of bone in an Italian family" pps
... development of the disease by impairing the binding of the p62 protein to a ubiquitinated target However, other molecular mechanisms, involving a key ubiquitinated substrate, could be invoked in the attempt ... though the presence of the M404V mutation could not be assessed in patient III-6, these hypotheses strongly support the need for further investigation into the possible role of the p62 protein in the ... and pain by living members of the family, strongly suggesting the presence of PDB disease in this individual Figure 2a contributes to sustaining this hypothesis The proband III-1, in whom the M404V...
Ngày tải lên: 09/08/2014, 07:20
báo cáo khoa học: " Adiponectin receptor-1 expression is associated with good prognosis in gastric cancer" pptx
... However, the role of adiponectin in cancer etiology is not yet fully understood Although adiponectin may provide indirect protection against carcinogenesis by affecting insulin sensitivity and inflammatory ... abolished the effects of adiponectin, although the effect of siRNA of adipoR2 was less prominent In our examination, adiponectin led to growth pg 14 inhibition in MKN45 and NUGC3 The two cell lines ... assisted the experiments IN, TF, and TO participated in the study design and coordination All authors have read and approved the final manuscript Competing interests The authors declare that they...
Ngày tải lên: 10/08/2014, 10:21
báo cáo khoa học: " Acquired A amyloidosis from injection drug use presenting with atraumatic splenic rupture in a hospitalized patient: a case report" potx
... referred to as ‘skin popping’, as in our patient [10] Skin popping is the injection of narcotics, commonly heroin, just under the skin Black tar heroin is used on the west coast of the USA and is ... to lead to increased production of AA protein in the liver; this protein is then released into the blood stream and deposited in small blood vessels throughout the body This protein deposition ... which was previously called Figure Hematoxylin and eosin staining results Hematoxylin and eosin stain of splenic tissue at 40 × magnification showing amyloid around a blood vessel (arrow) Roll...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: " Disseminated cutaneous Herpes Simplex Virus-1 in a woman with rheumatoid arthritis receiving Infliximab: A case report" docx
... data indicate that TNF-alpha may have an antiviral effect in HSV-1 infections In a model in which HSV-1 was reactivated in latently infected mice cornea, TNF-α and interleukin-6 were the predominant ... cytokines within the trigeminal ganglion suggesting a key role for these cytokines in viral clearance [5] Absence of TNF in knockout mice increased susceptibility to primary corneal HSV-1 infections ... acyclovir in immunocompromised patients has been found to be successful in reducing the duration of viral shedding and preventing clinical HSV infections in 80% to 100% of patients [10] The oral...
Ngày tải lên: 11/08/2014, 21:22
Báo cáo y học: " Natural killer cells control a T-helper 1 response in patients with Behçet''''s disease" doc
... months Two patients with intestinal flare were treated with infliximab, resulting in resolution of all intestinal symptoms within months The mucocutaneous flare in the remaining patient was improved ... was added at the initiation of the culture The T cells were then fixed and permeabilized using an Intracellular Cytokine Staining Kit Human® (BD Biosciences), and were subsequently stained with ... prednisolone in combination with an increase in the dosage of cyclosporine Activation status of natural killer cells We determined the activation status of the circulating NK cells in seven patients...
Ngày tải lên: 12/08/2014, 12:20
Báo cáo y học: "Evolution of antibody landscape and viral envelope escape in an HIV-1 CRF02_AG infected patient with 4E10-like antibodies" docx
... change in the envelope structure Another remarkable change in the gp160 sequence during Env evolution is the unique insertion in the C1 region The C1 region is part of the inner domain of the gp120 ... neutralization by inducing alanine substitutions in both epitopes For 2F5, the positions D664, K665 and W666 play a major role in the binding and recognition of the epitope In the case of 4E10, ... 4E10-binding (Fig 4) A similar observation was made for the plasma from ITM4 (Fig 4), the same peptide occupied the binding places for the antibodies binding the NWFNLTQTLMPR mimotope as for the...
Ngày tải lên: 12/08/2014, 23:22
Báo cáo y học: "Latency profiles of full length HIV-1 molecular clone variants with a subtype specific promoter" pps
... Arguably, the AE LTR might be less prone to become silenced due to the presence of the unique GABP binding site instead of the regular second NFB site present in the other subtypes The GA binding ... with the indicated viral inputs The results presented reflect the average of three independently produced virus stocks and each stock was used in two independent infections The HIV-1 input (ng/infection) ... extended time window The fusion inhibitor T1249 remained present in these cultures to prevent spreading of the input virus A sample of the cultures was split on day 2, and 14 and either TNFa or...
Ngày tải lên: 13/08/2014, 01:21
Báo cáo khoa học: "High mobility group box-1 protein in patients with suspected community-acquired infections and sepsis: a prospective study" pot
... functions, including inducing fever, anorexia, weight loss, and cytokine production in the brain; inducing acute lung injury and production of pro-inflammatory cytokines/mediators in the lungs; promoting ... characterised, and the sampling and processing of plasma/ serum were optimised We avoided work-up bias in the classification of the infectious status of the patients by blinding the clinicians and ... imaging technique, serologically documented infection, and obvious clinical infection (for instance, erysipelas and wound infection) The physician classifying the infection status of the included...
Ngày tải lên: 13/08/2014, 03:20