... recorded and the final two were averaged to determine the response at the end of the study Statistical analysis The change of paw withdrawal latency (PWL) for vehicle and drug treatment groups in the ... 0.05) between the vehicle and drug treatment groups contributes to the development and maintenance of neuropathic pain by inducing the synthesis of inflammatory cytokines and other neuroactive ... of Procter & Gamble Pharmaceuticals during the performance of these studies and received 100% of their compensation from the company Authors' contributions KKB, SAH and EBH performed all of the...
Ngày tải lên: 11/08/2014, 08:22
... three months of treatment Between the commencement of the new psychotropic treatment regimen in October 2007 and the significant improvement of the depressive symptoms as described above, the arthritis ... http://www.jmedicalcasereports.com/content/4/1/6 Page of Figure Development of Arthritis Pain, Depressed Mood and Level of Activity over time The graph describes the course of levels of arthritis pain, depressive symptoms and physical ... specific treatment (DMARDs and analgesics) had not changed While her CRP levels were 32 mg/L before the start of the new psychotropic treatment regimen, they dropped continuously to 13 mg/L Page of...
Ngày tải lên: 11/08/2014, 14:21
Báo cáo y học: "Spleen tyrosine kinase inhibition in the treatment of autoimmune, allergic and autoinflammatory diseases'''' pps
... Lck, and Janus kinase (JAK1) and JAK3, which may also be involved in the expression of autoimmune pathology [4] These non-Syk targets may enhance the clinical value of R406 in the treatment of ... the treatment of patients with RA Should Syk inhibitors attain approval for the treatment of RA, an opportunity may arise (provided that the cost is not too high) to try them in tandem with the ... expand in numbers, acquire immune cell features, produce proinflammatory cytokines and enzymes, and contribute to the inflammatory process and the eventual destruction of the joint A number of...
Ngày tải lên: 12/08/2014, 15:22
Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... across other populations [38,39] The effects of lamotrigine and topiramate on serum cholesterol and triglyceride levels have been reported in small studies and case reports [16,38] Neither of these ... phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks of exposure The frequency of the syndrome ... delayed As the physician with the most (and often the only) contact with these patients, psychiatrists need to be vigilant in detecting early signs and symptoms of medical illness and facilitating...
Ngày tải lên: 25/10/2012, 10:51
Báo cáo y học: " Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial"
... in the morning and two in the evening for a daily dose of 1500 mg glucosamine and 1200 mg chondroitin Removal of Patients from Therapy or Assessment The criteria for removal of patients from the ... (60.1%) and the fact that 78% of the participants were in the mild pain subgroup (21) Previous studies have shown that UC-II is effective in the treatment of RA (8-11), and preliminary human (12) and ... inhibit killer T-cell attack (15) The present clinical trial evaluated the safety and efficacy of UC-II in the treatment of the knee in OA patients Materials and Methods Study Design This clinical...
Ngày tải lên: 26/10/2012, 09:48
Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
... ª 2010 The Authors Journal compilation ª 2010 FEBS 555 Signaling mediators in the treatment of obesity M J Wolfgang and M D Lane One of the biggest challenges to the field is the lack of experimental ... in the short-term [27] Aside from the public health aspects of the affects of fructose on food intake, these findings lend further support to the mechanism by which malonyl-CoA participates in the ... lipid nutrient sensing in the brain and is an example of an enzyme that can sense and respond to the nutritional environment The major challenge to understanding the role of CPT1c is to determine...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Bevacizumab and cetuximab for the treatment of metastatic colorectal cancer docx
... from data in the RCT The survival of patients receiving ASC/BSC was calculated from the survival of the patients in the cetuximab monotherapy arm of the RCT The data from the monotherapy arm NICE ... evidence from the bevacizumab studies and noted that the age of the population in the largest study was lower than the age of patients normally receiving chemotherapy in England and Wales However, ... NHS practice in England and Wales 4.3.5 The Committee then considered the estimates of cost effectiveness of bevacizumab It noted that the models from the manufacturer and from the assessment group...
Ngày tải lên: 14/02/2014, 22:20
PROSTHETIC REHABILITATION OF MISSING TEETH AND ORAL HEALTH IN THE ELDERLY pptx
... 1967) The aim of this doctoral thesis was to describe the present prosthetic rehabilitation, the adequacy of received prosthetic treatment and subjective and objective needs for the prosthetic treatment ... extraction of teeth and progresses at varying speed for the rest of the life (Tallgren, 1972) Both local and systemic factors may affect the rate of RRR The role of local prosthetic factors in the RRR ... Retained and missing teeth and causes for the loss of teeth (Paper I) .27 8.2 Prosthetic rehabilitation of the edentulous elderly and adequacy of rehabilitation (Papers I, II) 28 8.3 Prosthetic...
Ngày tải lên: 05/03/2014, 18:20
Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
... present, and therefore more detailed understanding of adipocyte hyperplasia in humans is essential for the development of efficacious and safe treatments As emphasized here, RMI1 is one of the most ... development and subsequent clinical course of some types of obesity In this minireview, we focus on adipocyte hyperplasia as a novel therapeutic target for the treatment of obesity and discuss the merits ... expression of RMI1 and E2Fs in adipocytes, and these changes in expression are expected to increase a positive interaction between the molecules The increased expression of RMI1 and E2Fs thereby...
Ngày tải lên: 06/03/2014, 01:20
The Use of Mushroom Glucans and Proteoglycans in Cancer Treatment potx
... none of these criteria for effectiveness was met in a patient at the end of the trial period (six months), the treatment was judged ineffective Once the code was broken at the end of the trial and ... retrospective analysis of their success with combined radiation, chemotherapy, and immunotherapy in 133 cases.38 They concluded the addition of immunotherapy to the regimen using either PSK or OK-432 ... surgery and long-term chemotherapy By the early 1980s, once more reinforced by the results of Kodama et al,27 the use of PSK as the immuno-component of chemoimmunotherapy consistently doubled the...
Ngày tải lên: 06/03/2014, 02:21
Pelvic floor muscle training and adjunctive therapies for the treatment of stress urinary incontinence in women: a systematic review doc
... outcome of physical therapy? What is the optimal period of treatment and number of treatments? What is the effectiveness of physical therapy in clinical practice settings and can the findings in the ... the differences in outcome The expertise of health professionals may vary and also the quantity and quality of the educational information about the condition and PFM function The impact of these ... evidence for the optimal period of treatment and number of treatments? We found evidence for the efficacy of shorter treatment protocols than the 4–6 months recommended by the ICS The basis of the ICS...
Ngày tải lên: 28/03/2014, 14:20
SYNTHESIZE AND INVESTIGATE THE CATALYTIC ACTIVITY OF THREE-WAY CATALYSTS BASED ON MIXED METAL OXIDES FOR THE TREATMENT OF EXHAUST GASES FROM INTERNAL COMBUSTION ENGINE
... choice and loading of the NM is a compromise between the required efficiency of the converter and the market price of the NM However, the application of noble metals for the treatment of exhaust ... adsorption of reactant molecules on the semi-conducting surface; the formation of these is a function of the electronic properties of the solid, and the structure and kind of bonds (6) The catalyst ... begins with the adsorption of CO and O2 on the Nguyen The Tien 29 Synthesize and investigate the catalytic activity of three-way catalysts based on mixed metal oxides for the treatment of exhaust...
Ngày tải lên: 12/05/2014, 17:14
báo cáo hóa học:" Two levels above and one level below pedicle screw fixation for the treatment of unstable thoracolumbar fracture with partial or intact neurology" pot
... bending of the hardware, and segmental kyphosis after a caudad screw in the lumbar construct broke And they noted that untreated anterior instability, and pre-stressing of the screws when the rods ... drafting the manuscript and designing of data and revising it critically, KCN has contributed in acquisition of data and analysis and interpretation of data, and JHY has contributed in acquisition and ... shown that when there is loss of more than 50% of the vertebral body height or angulations of the thoracolumbar junction of more than 20° [8], acute spinal instability results, and the spinal segment...
Ngày tải lên: 20/06/2014, 04:20
báo cáo hóa học:" Granuloma debridement and the use of an injectable calcium phosphate bone cement in the treatment of osteolysis in an uncemented total knee replacement" doc
... operated the patient and is the senior author HA managed the patient and wrote the manuscript VR assisted with the literature review and manuscript preparation All authors have read and approved the ... data in the literature pertaining to the use of bone cements in the context of osteolytic cysts in knee arthroplasty, however these analogues have been successfully used in the treatment of benign ... image of the left knee showing the introducing cannula and simultaneous venting of the medial tibial condylar cyst Discussion When dealing with massive periprosthetic osteolysis the aims of surgery...
Ngày tải lên: 20/06/2014, 04:20
báo cáo hóa học:" The impact of iron overload and its treatment on quality of life: results from a literature review" pptx
... interviews Some of the patient interviews were historical and the primary purpose of those interviews was not to assess the QoL of the patients, but rather to assess their perceptions of current treatments ... experts representing the UK, US and Italy were interviewed about their observations of the impact of iron overload and its treatment on patients Results Literature review At the onset of this review, ... ICT, and by the condition (thalassemia, SCD, MDS) Figure provides an overview of the hypotheses for the impact of infusion ICT on the QoL of patients with iron overload In thalassemia, the impact...
Ngày tải lên: 20/06/2014, 16:20
Báo cáo hóa học: " Changing patterns in diagnostic strategies and the treatment of blunt injury to solid abdominal organs" docx
... resuscitation A determinant of the success of NOM is the level of cooperation between different specialists in the hospital Good teamwork among the trauma surgeon, the anesthesiologist and the (interventional) ... Twente, Enschede, The Netherlands 4Trauma Unit Dept of Surgery, Medisch Centrum Alkmaar, Alkmaar, The Netherlands 5Dept of Radiology, Academic Medical Center, Amsterdam, The Netherlands Authors’ ... determines whether there is any further need for imaging and what the treatment options are In case of gross hematuria, a MDCT scan is the gold standard for the evaluation of renal injury [58]...
Ngày tải lên: 21/06/2014, 01:20
Báo cáo y học: " Pregnancy and delivery while receiving vagus nerve stimulation for the treatment of major depression: a case report" pot
... enrollment in the VNS studies of patients with TRD, there have been no studies of the use of VNS therapy among pregnant patients A report of eight pregnancies in patients receiving VNS therapy for ... Inc., collected the data for this pilot study and encouraged the authors to submit this case report to help increase the understanding of VNS therapy and pregnancy References Andersson L, Sundstrom-Poromaa ... DSM-IV diagnosis of unipolar depression, was enrolled in the acute and long-term phases of the pilot study of VNS therapy for TRD At acute-phase study entry, she was noted to be obese and to have...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review" pdf
... Annals of General Psychiatry 2009, 8:16 the treatment of acute mania, the approval of quetiapine and the olanzapine-fluoxetine combination against acute bipolar depression and the approval of olanzapine, ... validity of psychiatric diagnosis perplexes the problem and makes the gathering of scientific data difficult, because the diagnosis of BD in particular is often made retrospectively and carries the ... by the US FDA in 2002 for the treatment of schizophrenia Recently it received approval for the treatment of acute manic and mixed in patients with bipolar I disorder and for the maintenance treatment...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "The opposite effects of fluvoxamine and sertraline in the treatment of psychotic major depression: a case report" potx
... fluvoxamine monotherapy was effective in the treatment of psychotic major depression, and the switch to sertraline worsened the psychotic symptoms in the patient The mechanisms underlying the opposite ... days after the switch to sertraline, the patient suffered from several delusions such as 'Neighbors kick the wall of the house at home', 'They talk about me on the TV news', and 'The environment ... that there are chopsticks in the hole of my nose' The sertraline was therefore stopped and was changed to fluvoxamine (150 mg) A week after fluvoxamine monotherapy treatment was given, the above...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action" pps
... [70] and IL-1αinduced PGE2 production [71] in a dose- and MW-dependent manner; the higher the MW and concentration, the more potent the inhibition Intra-articular injection of HA in the temporomandibular ... levels of prostaglandin F2α, 6-keto-prostaglandin F1α, and leukotriene C4 [72] In synovial fluid from the knees of patients with OA and RA, intra-articular HA reduced the levels of PGE2 [73,74] and ... In the synovium of HA-treated knees, the number and aggregation of synoviocytes decreased, and both treatments reduced the number of inflammatory cells, including macrophages, lymphocytes, and...
Ngày tải lên: 09/08/2014, 01:21