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Tài liệu Báo cáo khoa học: Novel aggregate formation of a frame-shift mutant protein of tissue-nonspecific alkaline phosphatase is ascribed to three cysteine residues in the C-terminal extension pdf
Ngày tải lên :
19/02/2014, 17:20
... support of this, this secretory form was found to be sensitive to PNGase F but resistant to Endo H (Fig 4B, lanes & 6) On the other hand, the GPI-anchor-less sTNSALP was efficiently secreted out of the ... embedded into the lipid bilayer via GPI, which helps anchor TNSALP to the plasma membrane, but is secreted out of the cell To investigate whether this mutant protein is secreted, we labeled the transfected ... referred to as TNSALP (1735delT) [16–18] According to the recommended nomenclature, the adenine of the FEBS Journal 272 (2005) 1704–1717 ª 2005 FEBS initiator ATG codon in the cDNA of TNSALP is...
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Báo cáo y học: " Activation of the SPHK/S1P signalling pathway is coupled to muscarinic receptor-dependent regulation of peripheral airways" pot
Ngày tải lên :
12/08/2014, 18:21
... and in the statistical analysis YB was involved in the design of the study and the immunohistochemical investigations The data presented in the manuscript are part of the doctoral thesis of PM, ... carbonate-buffered glycerol at pH 8.6 Omission of primary antisera or preabsorption of the SPHK1a antiserum with the corresponding synthetic peptide (20–100 µg antigen/ml diluted antiserum) abolished ... from that of the other mice used (for details see "Materials and Methods") Immunohistochemistry We used single-and double-labeling immunohistochemistry to examine the distribution of SPHK1 in murine...
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Eat for Life The Food and Nutrition Board''s Guide to Reducing Your Risk of Chronic Disease
Ngày tải lên :
09/08/2015, 12:31
... Academy of Engineering, and the Institute of Medicine The Institute of Medicine was chartered in 1970 by the National Academy of Sciences to enlist distinguished members of the appropriate professions ... in the examination of policy matters pertaining to the health of the public In this, the Institute acts under both the Academy's 1863 congressional charter responsibility to be an adviser to the ... http://www.nap.edu/catalog/1365.html AN EDITORIAL NOTE iii An Editorial Note This book is the result of the work of many people and draws on more than a decade of study by the Food and Nutrition Board It brings together the most...
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báo cáo hóa học: " Integration of immigrants into a new culture is related to poor sleep quality" pptx
Ngày tải lên :
18/06/2014, 19:20
... in the Moroccan immigrant sample (19%) Similar to the findings in the Moroccan sample, the percentage of blunters in the current sample was inconspicuous With respect to sleep, a total of 54% of ... with husbands and other family members were necessary to dispel doubts about the protection of privacy and the purely scientific nature of the investigation Due to low levels of literacy and poor ... religious customs and beliefs Monitoring is more than twice as prevalent in both groups of female immigrants compared to non-immigrant Germans, suggesting that coping style is related to the act of immigra-...
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Báo cáo khoa học: "Tezosentan-induced attenuation of lung injury in endotoxemic sheep is associated with reduced activation of protein kinase " doc
Ngày tải lên :
12/08/2014, 22:21
... that the binding of ET-1 to its receptor might induce the activation of protein kinase C (PKC) [15,16] Activation of the α isoform of PKC (PKC-α) might cause disturbances in the shape of the cells ... tezosentan reduced the slope of the regression line compared with LPS alone (P < 0.05; Fig 2) As shown in Fig 3, extracts of lung tissue from sheep exposed to LPS displayed a 75% reduction of the cytosolic ... Administration of tezosentan completely prevented the translocation of PKC-α from the cytosolic to the membrane fractions Figure shows that after hours of exposure to LPS, in parallel with the rise...
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Báo cáo y học: "Attributable cost of methicillin resistance: an issue that is difficult to evaluate" pps
Ngày tải lên :
13/08/2014, 01:20
... No Timsit evidence of the cost of MRSA infections and provide new arguments for funding the fight against MRSA spread in the ICU Competing interests The author declares that they have no competing ... 17:622-628 Rello J, Torres A, Ricart M, Valles J, Gonzalez J, Artigas A, Rodriguez-Roisin R: Ventilator-associated pneumonia by Staphylococcus aureus Comparison of methicillin-resistant and methicillin-sensitive ... methicillin-sensitive episodes Am J Respir Crit Care Med 1994, 150:1545-1549 Ibrahim EH, Ward S, Sherman G, Kollef MH: A comparative analysis of patients with early-onset vs late-onset nosocomial pneumonia in the...
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Up regulation of c EBPa in hepatocellular carcinoma is correlated to poorer prognosis
Ngày tải lên :
02/10/2015, 17:14
... Scoring of Tissue Microarray After the tissue microarray was stained through immunohistochemistry, they were scored based on the intensity of staining in the hepatocytes’ nuclei A score of indicated ... the aims of this study are to – Determine the expression levels of C/EBPα in HCC tissues Examine the correlation between the expression of C/EBPα in HCC and the HCC patients’ prognosis and other ... there I would like to also thank the members of Pathology lab as they had generously shared their resources and expertise with me And to the many others out there……thank you for rallying me to...
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Tài liệu BANKING ON OPPORTUNITY: A SCAN OF THE EVOLVING FIELD OF BANK ON INITIATIVES docx
Ngày tải lên :
16/02/2014, 06:20
... programs exist and their locations The purpose of this report is to describe the landscape of Bank On programs, their origins, and their context within a broader financial access field The report provides ... providers to meet their transaction needs.21 This information – in addition to the prominence of the subprime mortgage and foreclosure crisis – has increased the visibility of financial access issues ... Scan of the Evolving Field of Bank On Initiatives A Scan of the Evolving Field of Bank On Initiatives BANKING ON OPPORTUNITY with the Spanish-language television and media company, Univision, to...
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Tài liệu Painting with print: Incorporating concepts of typographic and layout design into the text of legal writing documents docx
Ngày tải lên :
21/02/2014, 05:20
... The Journal of the Association of Legal Writing Directors is a publication of the Association of Legal Writing Directors Its mission is to advance the study of professional legal ... “wing” is the extra little line dangling on the bottom of letters Look carefully at the bottoms of the letters in this and the next sentence You will most easily see these lines on the bottoms of the ... permit the user to set spacing to “exactly points.” A point is 1/72 of an inch In other words, the writer may set the spacing between the lines to 1/72 of an inch Usually the leading is automatically...
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Đề tài " The number of extensions of a number field with fixed degree and bounded discriminant " docx
Ngày tải lên :
06/03/2014, 08:21
... in terms of ∆L There are only finitely many such polynomials, and counting them gives the theorem of [18] The main idea of Theorem 1.1 is to count r-tuples of integers in L instead of single ... order to verify the hypothesis of Lemma 2.1 Lemma 2.3 Let V be a F -subspace of F n of dimension m, and let Σ0 ⊂ be a subset of size m Let Z ⊂ V r be the subset of points x ∈ V r such that the ... so we may speak of χσ (x(j) ) ∈ F for ≤ j ≤ n By abuse of notation we also use π to denote the projection of (F n )r onto (F m )r Then the restriction of π to V r is an isomorphism V r ∼ F mr...
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MATHEMATICS REVISED BASED ON THE RECOMMENDATIONS OF THE TEXT BOOK DEVELOPMENT COMMITTEE pptx
Ngày tải lên :
08/03/2014, 12:20
... vector is the sum of all the vectors This is called the polygon law of addition of vectors Fig 43 → → Note : It should be noted that the magnitude of a + b is not equal to the sum → → of the ... such that the magnitude of the vector is the length of the Fig line segment AB and its direction is that from A to B The point A is called → initial point of the vector AB and B is called the terminal ... vector The zero vector is denoted by O Vectors other than the null vector are called proper vectors Unit vector: A vector whose modulus is unity, is called a unit vector → ^ The unit vector in the...
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Báo cáo Y học: Amphipathic property of free thiol group contributes to an increase in the catalytic efficiency of carboxypeptidase Y pot
Ngày tải lên :
08/03/2014, 23:20
... because of the elasticity introduced The size of the S1 subsite may also be reduced as the result of shrinkage of the hydrophobic side chains in the surface of the S1 pocket which is exposed to solvent ... nitrogen of which is positively charged (Fig 4) The thiol group of ˚ Cys341 is located within A of the imidazole nitrogen of His397 Therefore, it is reasonable to assume that the sulfur atom of Cys341 ... the point of the active Ser˚ His diad The sulfur atom of Cys341 is located within A of the imidazole ring of His397 designed to maintain hydrophobicity and Gly, Ser, Asp and His mutants to provide...
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Examination Guidelines for Patent Applications relating to Biotechnological Inventions in the Intellectual Property Office
Ngày tải lên :
13/03/2014, 21:48
... anything inventive is done for the first time it is the result of the addition of a new idea to the existing stock of knowledge Sometimes, it is the idea of using established techniques to something ... of the claim in question is then construed, and the differences between the state of the art and the inventive concept of the claim are identified This then enables the examiner to approach the ... exercise to the skilled person to see whether the substitutions produced a polypeptide having the activity of the protein This is very different from the situation49 which arises in the field of...
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Báo cáo " MODEL OF CONDUCTIVITY FOR PEROVSKITES BASED ON THE SCALING PROPERTY OF GRAIN BOUNDARY " ppt
Ngày tải lên :
14/03/2014, 13:20
... according to the following procedure First, measure the total area of each SEM photograph, then divide this area into the smaller squares and use them to fill each grain area The number of squares ... method and the apparature settlement, the obtained D only refers to the applied apparent resistivity At this moment there is no way to prove that D really corresponds to the true boundary resistivity ... media, the grain itself with size L and resistivity ρG and the boundary with thickness L’ and resistivity ρB The net resistivity is: (6) ρ = ρG + (L /L)ρB Since the grains consist of the disordered...
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Báo cáo khoa học: Zinc-binding property of the major yolk protein in the sea urchin ) implications of its role as a zinc transporter for gametogenesis ppt
Ngày tải lên :
16/03/2014, 05:20
... in the ovary at stage and 13% of the total zinc in the testis at stage is still bound to MYP On the basis of the results of the present study and others, we propose a model for the synthesis ... measured the protein content of the CFMYP and EGMYP bands by densitometry of the SDS ⁄ PAGE gel of the purified MYP, and the ratio of CFMYP to total MYP (CFMYP + EGMYP) was calculated (Fig 3B) In the ... localization of the labeled MYP Statistical analysis Data were expressed as the mean ± SEM Statistical analysis was performed using instat software (GraphPad Software) The normality of the distribution of...
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Báo cáo khoa học: Kinetic study of the HIV)1 DNA 3¢-end processing Single-turnover property of integrase docx
Ngày tải lên :
16/03/2014, 13:20
... which is believed to be the IN cofactor in vivo, is not equivalent to Mn2+ in vitro The specicity of catalysis is greater with Mg2+ and the choice by the enzyme of the nucleophile for the 3Â-processing ... corresponds to the time required to perform 50% of the total reaction The stability of IN in the presence of Mg2+ and the fact that this stability might be further increased when IN is bound to DNA ... cycling mode of catalysis In most cases, the functional reason for the tight binding of the reaction product to the catalyst is not clear In the case of IN, tight binding of the protein to recessed...
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Synthesis and photoluminescence property of silicon carbon nanowires synthesized by the thermal evaporation method
Ngày tải lên :
16/03/2014, 15:21
... [23] of SiC, the emission peak for b-SiC nanowires is obviously shifted to the blue The emergence of the peak with a blueshift is due to the existence of oxygen defects in the amorphous layer, the ... temperature to adjust the pore diameter and remove the barrier layer at the bottom of nanoholes 2.2 Synthesis of SiC nanowires The preparation apparatus for synthesis of SiC nanowires is a conventional ... characteristic absorption peaks are quite intense possibly due to the SiO2 outer layers of the SiC nanowires; this confirms the composition of nanowires To investigate PL properties of the synthesized...
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Báo cáo khoa học: "Redundancy Ratio: An Invariant Property of the Consonant Inventories of the World’s Languages" pdf
Ngày tải lên :
17/03/2014, 04:20
... FE is therefore the measure of the minimum number of bits that is required to communicate the information about the entire inventory through the transmission channel The lower the value of FE the ... results of the t-test comparing the distribution of RRs for the consonant and the vowel inventories Figure 5: The scatter-plot of the redundancy ratio RR of each of the vowel inventories (y-axis) ... consonant inventories of a particular size (y-axis), versus the inventory size (x-axis) Null Hypothesis: The nature of the distribution of RRs for the vowel and the consonant inventories is same We...
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maxwell jc - a dynamic theory of the electromagnetic field
Ngày tải lên :
04/06/2014, 12:44
... Cp*u+Opqv the momentum of C referred to A, and Cpqu+Ctfv its momentum referred to B then we may say that the effect of the force X is to increase the momentum of C referred to A, and that of Y to increase ... each other in virtue of their connexion with the magnetization of the propose to examine, conductors in the The second is field The first result of this connexion that I the induction of one ... consists in the transmission of electricity a body to another Let the quantity of unit of area perpendicular to the axis of from one part of electricity transmitted in unit of x be called jp, p then...
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To navigate the text, please use the electronic Table of Contents docx
Ngày tải lên :
19/06/2014, 08:20
... About the pagination of this eBook Due to the unique page numbering scheme of this book, the electronic pagination of the eBook does not match the pagination of the printed version To navigate the ... draw pictures of the place you went or the things you did Don’t put anything important in the center of the frame where the photograph will go Now glue your photograph in the center of the frame, ... help with measuring and cutting, but let them put their project together without the pressure to make these measurements, or the placement of the photo or other objects, completely exact Your child...
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