the structural biology of muscle spatial and temporal aspects
EVOLUTION OF THE MOLECULAR BIOLOGY OF BRAIN TUMORS AND THE THERAPEUTIC IMPLICATIONS pdf
... Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications high grade gliomas The structure and compounds of the ECM of the brain tissue have many specific differences from other ... infiltrate the enviro‐ ment and form it similar to the tumor tissue The process of the peritumoral invasion de‐ pends on the confrontation zone of the tumor cells and the non-neoplastic cells and ECM ... mortality of the patient Moreover, the presence of the blood-brain barrier (BBB) limits the passage of a wide variety of anticancer agents The high incidence of recur‐ rence and poor prognosis of malignant...
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Báo cáo sinh học: " Molecular advances in the cell biology of SARS-CoV and current disease prevention strategies" doc
... understand the viral replicative strategy and devise prophylactic measures In the wake of the SARS epidemic, a number of excellent review articles on the clinical and molecular aspects of SARS epidemiology ... administration of corticosteroids [44,45] Since then, the wealth of information that has emerged on SARS-CoV molecular and cellular biology, as updated in the preceding sections of this review, now offers ... molecular aspects of SARS-CoV biology and how such information may lead to strategies for disease prevention The clinical symptoms of SARS are those of a lower respiratory tract infection and are...
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báo cáo hóa học:" Molecular advances in the cell biology of SARS-CoV and current disease prevention strategies" pot
... understand the viral replicative strategy and devise prophylactic measures In the wake of the SARS epidemic, a number of excellent review articles on the clinical and molecular aspects of SARS epidemiology ... administration of corticosteroids [44,45] Since then, the wealth of information that has emerged on SARS-CoV molecular and cellular biology, as updated in the preceding sections of this review, now offers ... molecular aspects of SARS-CoV biology and how such information may lead to strategies for disease prevention The clinical symptoms of SARS are those of a lower respiratory tract infection and are...
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Báo cáo y học: " The cell biology of HIV-1 and other retroviruses" pptx
... HIV-1 and other viruses [45] This work highlighted the importance of host proteins and machineries in the targeting of viral components during the gene expression and assembly phases of the retroviral ... targeting the binding of modified U1 snRNPs to regions of RNA adjacent to the polyadenylation signal The magnitude of the inhibition observed coupled with the high degree of conservation of http://www.retrovirology.com/content/3/1/77 ... components of the cellular endosomal sorting machinery, which regulate the delivery of cargo proteins into the MVB pathway, and the biogenesis of the vesicles that bud into MVBs Three types of retroviral...
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Spatial-temporal Dynamics of Rubber Plantation in the Border Region of China, Laos and Myanmar: 1980-2010 pdf
... distributed on other four aspects the planted intensity increased gradually in different aspect gradients •mainly distributed more on south and east aspects than on north and west aspects, and the planted ... Interpretation of Rubber Plantation Spatial- temporal Pattern of Rubber Plantation Topographic Features of Rubber Plantation Summary and Prospect Current Spatial Pattern of Rubber Plantation ... showed the similar trend Change pattern (1980-2010): The proportion gradually declined on the flat and north aspects, while rose continually on the south aspect, and decreased firstly then increased...
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Báo cáo lâm nghiệp:"The d13C of Scots pine (Pinus sylvestris L.) needles: spatial and temporal variations" pps
... in the d13C of growth rings of the branch and of the trunk [9] To study the temporal changes in bulk needle d13C by sampling needles in regular temporal intervals, the variability due to spatial ... on the branch; and (4) the temporal patterns of the different needle generations for bulk needle d13C corrected for spatial effects and the influence of environmental factors on the detected temporal ... collected and the absolute distance from the base of the branch was determined; (b) graphical representation of a transect for each growth year at the end of the experiment where 1, and are the growth...
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Báo cáo Y học: Monitoring the structural consequences of Phe12 fi D-Phe and Leu15 fi Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf
... the exposure of the hydrophobic core of Phe12, Aib15 and Val18 to the solvent, while establishing the structural basis for the side-chain interaction of the charged residues Arg16 and Glu20 The ... from the imine He proton and ˚ 3.644 and 5.121 A from the proximal guanidyl Hg11 and Hg12 protons of Arg16 (Fig 3B) On the other hand, the ˚ Oe2 atom of Glu17 is found at 5.485 A, far from the ... sequence of the peptide, either through the nature of the side chain of the new amino acids or through their non-native conformational features, increase the peptide–CRH complex stability with the...
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Báo cáo khoa học: The structural comparison of the bacterial PepX and human DPP-IV reveals sites for the design of inhibitors of PepX activity pot
... group of the ligand and the NH2 of Asn470 (equivalent to Asn710 in DPP-IV) Another potential bond can be proposed between the OH atom of Tyr380 and the carbonyl group of the ligand Finally, the ... lactis The results are presented in Table and Fig 4A For the cluster of lowest energy, both the position and the conformation of the ligand are close to those observed in the 3D structure of the ... comparison of the active and specificity sites of the two X-PDAP enzymes, the bacterial PepX (green) and the human DPP-IV (orange) (B) Superposition of the active and specificity sites of the S9 enzymes...
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Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx
... could influence the shortening processes of the assembled PufX protein The exchange of ubiquinone between the RC and the cyt bc1 in the presence of mutated PufX protein The role of the PufX protein ... neither affects the photosynthetic capability of the bacteria nor the efficiency of exchange of the ubiquinol molecules between the RC and the bc1, as judged from the reduction kinetics of cytochrome ... important role in the structure of the core complex [12], we decided to investigate the possible structural role of the N-terminus and the C-terminus of PufX To this aim, nine strains of Rb sphaeroides...
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Báo cáo hóa học: " Spatial and temporal EEG dynamics of dual-task driving performance" pdf
... all the power increases in the same temporal period and the same frequency band The open bars represent the total power in the theta band The gray bars represent the total power in the beta band ... the case of the single math task, the response time is the shortest and the theta power increase is the weakest Among the dual-task cases, the longest response time and the greatest theta power ... data, and the modification of paper to submit TTC participated in the design of the study and performed the statistical analysis HZL participated in the design of the study and drafted the manuscript...
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Báo cáo hóa học: " Spatial and temporal dynamics of cellulose degradation and biofilm formation by Caldicellulosiruptor obsidiansis and Clostridium thermocellum" ppt
... on the growth and structure of cellulolytic biofilms After the initial attachment phase when the bacteria form inverted colonies and depressions in the substrate, the biofilm maintains a thin and ... experiment The use of flat cellulose substrates coupled with sampling the biofilm structure at multiple stages of development allowed dissection of the multi-step process of biofilm formation and cellulose ... many of the cells are positioned vertically on the cellulose surface (Figures 2a and 3a) Whether this positioning is due to physical crowding of the cells on the surface or is the result of a...
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Báo cáo hóa học: " Research Article Automatic Generation of Spatial and Temporal Memory Architectures for Embedded Video Processing Systems" docx
... where WRi is the width of the GMO, nlines is the number of required memory objects for an operator, and w p is the bit width representing a pixel The length of the GMO is equal to that of the memory ... by the FPGA thus ensuring optimal usage of the block RAMs The algorithm takes advantage of the dual port capabilities of the block RAMs to achieve optimal allocations and the possibility of allocating ... each of the five line pairs (the dashed line is the SRAM and the marked line is the SDRAM) The graph shows that the performance exceeds the HDTV performance 1367 ¢ 768 progressive mode for a temporal...
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CURRENT BASIC AND PATHOLOGICAL APPROACHES TO THE FUNCTION OF MUSCLE CELLS AND TISSUES – FROM MOLECULES TO HUMANS pdf
... from the VSMC expression of the fast isoform of smooth muscle myosin heavy chain (MHC) which determines the velocity of shortening during vasomotion (rev [61]) Of note, lent isoform of smooth muscle ... the movement of the myosin heads still remains as a matter of debate and speculation The reason for the present situation in the field of muscle research arises from the fact that the myosin head ... Longitudinal arrangement of actin and myosin filaments within a sarcomere Note that the half sarcomere is the structural and functional unit of muscle (Sugi, 1992) On the other hand, actin filaments...
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THE STRUCTURAL DESIGN OF TALL AND SPECIAL BUILDINGS doc
... motions of the pair The vector of the response spectra is calculated as the square root of the sum of the squares (SSRS) of the response spectra for the two different directions, and this vector ... representative of the overall loaddeformation behavior of the building and compute a response history using appropriate software (e.g., Hachem, 2004) Dynamic analysis of the oscillator under the design ... sdof nonlinear static analyses on the one hand, and complications of complete threedimensional nonlinear dynamic analyses on the other, have led to some applications of simplified multidegree -of- freedom...
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Báo cáo lâm nghiệp: "Spatial and temporal diversity of wood decomposer communities in different forest stands, determined by ITS rDNA targeted TGGE" potx
... Douglas-fir and beech at the same time The species composition of the young beech stand was rather similar to the community observed in the native forest Nevertheless, both beech and spruce stands had ... increased The length of the arrows indicates the relative importance of the species/variable in explaining the variability between profiles The angle between the arrows indicates the degree to which they ... indicates the relative importance of the variable in explaining the position of the tree species in the ordination space The angle between the arrows indicates the degree to which they are correlated...
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PSYCHIATRY, PSYCHOANALYSIS, AND THE NEW BIOLOGY OF MIND - PART 2 ppsx
... remarkable, and the commitment of the faculty to the training of the house staff and to the treatment of the patients was admirable Moreover, I am describing the predominant trend at the center; there ... evaluation of the outcome of psychotherapy 40 Psychiatry, Psychoanalysis, and the New Biology of Mind I now consider each of these principles in turn and illustrate the experimental basis of this ... ourselves and each other? The only way to encourage the responsible use of this knowledge is to base the uses of biology in social policy on an understanding of biology The unease of social scientists...
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PSYCHIATRY, PSYCHOANALYSIS, AND THE NEW BIOLOGY OF MIND - PART 5 ppsx
... into the nature of replication This soon led to the discovery of mRNA, the deciphering of the genetic code, and an understanding of the mechanism of protein synthesis By 1965, we were well on the ... move out of the cell, and this event, together with the inactivation of the Na+ channel, repolarizes the cell and terminates the action potential Over the last several years, the ionic hypothesis ... symposium and the recent progress in molecular neurobiology have contributed to our understanding of the signaling of nerve cells and their patterns of development and interconnection The patterns of...
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PSYCHIATRY, PSYCHOANALYSIS, AND THE NEW BIOLOGY OF MIND - PART 6 pptx
... what the structure of DNA did for the rest of biology It unified the cellular study of the nervous system in general, and in fact, the study of ion channels in general One of the strengths of the ... different organic and inorganic ions of specified size to provide the first estimates of the size and shape of the pore of the Na+ and the K+ channels These experiments led to the defining structural ... learning and memory, and may even be important in primates for aspects of arousal and attention Although we are now only beginning to enter the era of the structural biology of voltage and of ligand-gated...
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PSYCHIATRY, PSYCHOANALYSIS, AND THE NEW BIOLOGY OF MIND - PART 7 pptx
... indicates the size of the displacement of the dot and thus the degree of apparent motion Note the general similarity between the performance of the human and that of the monkey and the devastation ... began by investigating the patterns of vibration of the various components of the inner ear, and the relationship of these patterns to the characteristics of sound waves From these observations he ... studies of the influence of target cells on the control of the neuronal number In the 1930s and 1940s, Samuel Detwiler, Viktor Hamburger, and others showed that the number of sensory neurons in the...
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PSYCHIATRY, PSYCHOANALYSIS, AND THE NEW BIOLOGY OF MIND - PART 10 pot
... spanned the transition from the twentieth century to the twenty-first century—have produced both the elucidation of the human genome and an increased understanding of the biology of the human ... in the sequence of bases in DNA In the 1960s and 1970s, our understanding of genes was further enhanced by the cracking of the genetic code, the three-letter alphabet whereby the sequence of ... application of these and other molecular insights made possible genetic engineering and more recently the sequencing of the human genome The current generation of physicians will be the first to reap the...
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