... analyzed only for the arms comparing GC therapy with no-GC exposure If studies were explicit in describing the methods by which they captured infection, nonreporting of infection within the results ... existed within the studies Even after stratification within any chosen domain, many differences remained inthe other areas of potential heterogeneity, and the I values often remained high Nonetheless, ... nonGC patients Ten of 21 studies had no reported infections in either arm, and four further studies had no infections in one ofthe two arms The estimated relative risk of infection associated with...
... duration of weaning and the total duration of MV The 21 patientsinthe ET group were demographically similar to the 53 patientsinthe ST group, except for the greater number ofpatientswith TBI in ... a point that has been defined by other investigators as 'early' Nonetheless, the findings of our study provide the basis for re-examining whether the timing of tracheostomy may impact clinical ... their sole injury or in addition to torso and extremity injuries The remaining patients had various surgical problems including intra-abdominal sepsis and ruptured abdominal aortic aneurysm Patients...
... values in groups ofpatientswith inflammatory arthritis with varying arthritis states and degrees ofdisease severity Methods Patients and Setting Data were taken from three cohorts ofpatientsThe ... to use these mapping functions in future studies In these circumstances, the performance ofthe mapping function in estimating utility values needs to be assessed and the likely impact of decisions ... Similarly, the difference between observed and predicted values ofthe EQ-5D at baseline and for change over time inthe very early diseasepatients were inthe range of previous estimates ofthe MID...
... Assessment of at least moderate diseaseThe REVEAL study was conducted in accordance withthe principles ofthe Declaration of Helsinki, and all study sites received approval from independent ... for the study, patients were required to meet the following disease severity indices at the baseline visit: moderate to severe plaque psoriasis defined as ≥ 10% BSA involvement, a PASI score of ... symptomatology, including pain and itching, combined with concerns about the appearance of one's skin can substantially affect a patient's psychological well-being and can result in emotional distress,...
... ofthe study protocol and the informed consent document The study was initiated at each site after the principal investigator and the study sponsor obtained approval documents The principal investigator ... trial of oncedaily ruboxistaurin for vision loss inpatientswith diabetic retinopathy The clinical findings and characteristics of this trial have been reported previously [22] A total of 684 patients ... this link over time Thus, the purpose ofthe current study was to examine the degree of change in HRQL that is associated with visual acuity changes among patientswith diabetic retinopathy Patients...
... assessments of fear of falling have not previously been included in studies when investigating the effect of STN stimulation Inthe present study, thepatients rated their fear of falling as less ... Up & Go [34,36] The subject is sitting in an armchair (seat height of 46 cm) withthe back against the chair and arms resting on the chair's arms The instruction "Go'' initiates the subject to ... placed on a line in front of each other, toes touching the heel ofthe other foot The test is performed on preferred foot (placed as the rearmost) with straight knees and arms hanging Timing commence...
... ofthe study protocol and the informed consent document The study was initiated at each site after the principal investigator and the study sponsor obtained approval documents The principal investigator ... trial of oncedaily ruboxistaurin for vision loss inpatientswith diabetic retinopathy The clinical findings and characteristics of this trial have been reported previously [22] A total of 684 patients ... this link over time Thus, the purpose ofthe current study was to examine the degree of change in HRQL that is associated with visual acuity changes among patientswith diabetic retinopathy Patients...
... Sociodemographic and clinical characteristics ofthe sample are shown in Tables and The percentage of missing values in each ofthe items contained inthe questionnaire was less than 5% The mean completion ... discriminative power The characteristics ofthe sample may limit the scope of use of this measure Therefore, it may be arguable whether patientswith greater involvement (that is, patientswith ... version 2.0) Finally, all the expert translators participated inthe proof reading test ofthe intermediate version 2.0, and the final Spanish version was thus established Subsequently, the Spanish...
... severe ofthe three diseases, exerting the greatest impact on physical aspects of HRQoL However, the cohorts of previous studies that compared the HRQoL ofpatientswith RA to that ofpatientswith ... primarily ofpatientswith mild-to-moderate disease [3,4] Disease severity is an important factor influencing the HRQoL ofpatients Therefore, the objectives of this study were to compare the HRQoL of ... included 1,987 patients from four clinical trials in which the safety and efficacy of infliximab was evaluated in rheumatic diseases Two ofthe trials were conducted inpatientswith RA: the Anti-TNF...
... Vitamin D binding protein (Gc-globulin) Endocr Rev 1989, 10:294-307 18 Lind SE, Smith DB, Janmey PA, Stossel TP: Roleof plasma gelsolin and the vitamin D-binding protein in clearing actin from the ... much lower for the platelet lysate, which contains mainly the cGSN isoform This indicates the specificity ofthe α-pGSN antibody for the pGSN isoform and shows that the main isoform in SF is pGSN ... to the presence of Gc-globulin [43], the pool of free actin monomers in SF is likely to be low, favoring depolymerization from the pointed (slow-growing) ends ofthe actin filaments (5) Actin...
... exploring the possibility that interventions must also be congruent withthe nature ofthedisease or diseases ofthepatients being cared for Diseases may mediate the way that interventions influence ... improve the performance of a clinical system to be most effective, they must take into account not only the nature ofthe system, but also the nature ofthediseaseThe purpose of this paper is twofold ... patient’s care The level of complexity of different diseases, and the ways that chronic diseases Page of 10 impact patients lives, varies greatly depending on the type of disease, leading to the need...
... and minimises the impact of observer-subject interaction on the measurement of blood pressure inthe clinical setting [33] Theroleofthe observer in recording the systolic pressure is eliminated ... sclerosis, causes the hardening and incompressibility of arteries which can affect the accuracy of ABIs [17,18] The hardening ofthe artery is due to to the stiffening ofthe elastic layer ofthe arterial ... pressures; the reliability was not investigated using a manual PPG unit Additional points withthe past research include difficulty in interpreting the results as the error range inthe units of measurement...
... relating to individual staff's perceptions ofthe clinical care of their patientswith type diabetes, team functioning, and practice organisation Choosing theories The theoretical frameworks included ... together explained 31% ofthe variance in diabetes management These authors, along with others [4,5], identified the need for a better understanding ofthe relationship between the quality of ... high rates of measurement of clinical and biochemical parameters but lower rates of acting on the results Only 67% of practices achieved the target of 50% ofpatients having their hemoglobin A1c...
... relating to individual staff's perceptions ofthe clinical care of their patientswith type diabetes, team functioning, and practice organisation Choosing theories The theoretical frameworks included ... together explained 31% ofthe variance in diabetes management These authors, along with others [4,5], identified the need for a better understanding ofthe relationship between the quality of ... high rates of measurement of clinical and biochemical parameters but lower rates of acting on the results Only 67% of practices achieved the target of 50% ofpatients having their hemoglobin A1c...
... wide range of physical and mental disorders The goodness of fit indices obtained withthe CFA models together withthe high factor loadings confirmed the domain structure of WHODAS-2 and the global ... withthe proportion of respondents neither working nor being students The moderate percentage ofpatientswiththe best possible score in several domains suggests the possible unsuitability of ... baseline and the third evaluation of these patients were conducted In this case, the magnitude ofthe difference was also assessed with ES coefficients, but computed dividing the difference in the...
... in a larger set of ALI patients, then a low or decreasing respiratory system compliance, interpreted inthe context of other known predictors of mortality in ICU patients, may help identify patients ... included in this study The 56 (149 minus 93) patients excluded from the original cohort were either extubated (27 patients) or died (29 patients) before the th day of mechanical ventilation The ... Y: Theroleof intraalveolar fibrosis inthe process of pulmonary structural remodeling inpatientswith diffuse alveolar damage Am J Pathol 1987, 126(1):171-182 27 Meduri GU, Tolley EA, Chinn...
... However, theroleof biomarkers inthe evaluation ofpatientsinthe ICU setting remains largely unexplored Because hemodynamic monitoring is a frequent theme inthe evaluation ofpatientsinthe ... useful in that they may allow invasive monitoring to be avoided in some patientswith heart failure inotropic agents (including norepinephrine [noradrenaline], phenylephrine, vasopressin, dopamine, ... filling pressures, to evaluate the utility of NT-proBNP to predict ICU death inpatientswith shock, and to examine theroleof NT-proBNP with other biomarkers in estimating prognosis in the...
... higher in our study group The mortality ofpatientswith pneumonia was 43.3% and the mortality ofpatients without pneumonia was 29.6% The baseline lung conditions of these patients was a Page of ... determining the appropriate level of PEEP requires maintaining PEEP-induced reopening of atelectatic areas and avoiding PEEP-induced lung overinflation Higher than traditional PEEP levels together ... had performed the weaning trial within a week of enrollment The incidence of barotrauma was similar in both groups The durations of mechanical ventilation, ICU stay and use of paralysing or sedative...
... lỗ, tính theo công thức: PREn = %Cr + 3,3x% Mo + 16x%N (1) Ngay thành lập chắn yếu tố hợp kim hiệu đóng vai trò quan trọng kháng ăn mòn rỗ DSS, người ta phải xem xét PREn biểu theo kinh nghiệm ... alloy duplex stainless steels (DSS) thường gọi thép lean duplex steel, làm tăng thêm tính đa dạng thép sử dụng gia cố bê tông Những loại DSS với thành phần Ni Mo thấp, tác động kinh tế thấp cấu ... rỗ nhiều báo gần đây, Alvarez đồng nghiên cứu hoạt động ăn mòn hai loại tôn sóng lean duplex stainless steels (SAF 2001 2304) Thử nghiệm 2.1 Vật liệu Bốn DSS nạc khác với hai nồng độ khác Mo nghiên...