the role of proteins in the formation of domains in membranes
Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf
... Protein targeting to the microsomes requires the cotranslational insertion of the newly synthesized protein into the microsomal membrane, where the N-terminal hydrophobic signal sequence of the ... localized inside of the inner membrane Moreover, the imported + ⁄ 1A1 and + 33 ⁄ 1A1 proteins were extractable with alkaline Na2CO3 as shown in Fig 2C, suggesting that both proteins are localized in the ... mitochondria-targeting signal in the yeast system Mitochondrial localization of intact CYP2E1 in yeast cells Because of the existing ambiguity in the literature on the nature and extent of CYP2E1 import into...
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investigating the role of the escrt proteins in cytokinesis
... Investigating the role of the ESCRT proteins in cytokinesis Musab Saeed Bhutta B.Sc (Hons) Thesis submitted in fulfilment of the requirements for the Degree of Doctor of Philosophy ... is involved in the formation of the contractile ring Shortly after the daughter cells separate, actin is localised at the newly divided end of the cell It then localises to both poles of the ... at the spindle midzone and midbody during mitosis and cytokinesis On the other hand, CDC14B is found predominantly in the nucleolus of interphase cells, and then at the spindle apparatus of mitotic...
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Single molecule studies on the role of nucleoid associated proteins in bacterial chromatin
... consists of N-terminal domain for protein oligomerization, C-terminal domain for DNA binding, and flexible linker connecting the two domains [48, 51] The central region of H-NS, which includes the ... as the reference point from the centroid of the magnetic bead to determine the extension of the stretched DNA Note that when the extension of the DNA is ⇠ µm, the image of the bead is near the ... containing DNA-binding protein of our interest, we can study the DNA binding properties of the protein by its impact on DNA elastic response (Fig 2.3) Theoretical predictions have shown that binding...
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Role of the survival proteins hsp27 and survivin in a small molecule sensitization to TRAIL mediated apoptosis 1
... that involves DISC formation and where the initiator caspase-8 plays a major role On the other hand, an intrinsic pathway, in response to signals affecting the mitochondria, that involves the formation ... Domain (CARD) for caspase-2 and -9 These domains allow their recruitment by adaptor proteins into the DISC or the apoptosome Recruitment of the initiator pro-caspases to these complexes results in ... the release of the cytokines in their soluble forms These ligands have a 20-30% homology in a 150 amino acid domain, known as the TNF homology domain (THD), which is responsible for the binding...
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Role of the survival proteins hsp27 and survivin in a small molecule sensitization to TRAIL mediated apoptosis 2
... 34B) Interestingly, down-regulation of survivin protein levels upon treatment with LY30 was inhibited in the presence of the proteasome inhibitor lactacystin Inversely, inhibition of protein synthesis ... independently of the presence of LY30, both resulted in a marked increase in cell death as reported in several studies Inhibition of the proteasome lead to an expected increase in survivin protein level in ... area covered by mitochondria against the ratio of the highest mitochondrial staining intensity to the total mitochondrial staining (A) Corresponding histogram of the mitochondrial aggregation (B)...
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The role of respiratory proteins in innate immunity
... name the bactericidal peptides derived from heme-containing proteins The evidence for the role of hemocidins in the innate defense against infection accumulated in many organisms Interestingly, ... overcome the host immune defense The host serine proteases have been examined in- depth regarding their roles in initiating and transducing the antimicrobial responses However, the probable roles of ... immunity of invertebrates Within minutes after infection, the microbial invader is encapsulated within an insoluble melanin capsule, and the generation of free radical byproducts during the melanin formation...
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The role of CDC42, 1RSP53 and its binding partners in filopodia formation
... G-actin and F-actin forms The rate of cycling is determined by actin binding proteins (ABPs) which includes the sequestering proteins and the capping proteins Sequestering proteins inhibit polymerization ... actin subunits and capping of existing actin filaments This group of proteins is collectively known as actin binding proteins (see figure 1.3) β-thymosin is the most abundant of these actin-monomer ... 1.3.3 Actin binding proteins Regulation of polymerization and depolymerization of actin is carried out by a group of proteins that are responsible for the crosslinking, severing, sequestering of monomeric...
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The role of TRIP br proteins in the regulation of mammalian gene transcription and cell cycle progression
... Features PHD zinc finger protein PHD zinc finger protein Composite PHD zinc fingerbromodomain proteins PHD zinc finger protein Bromodomain protein PHD zinc finger proteins PHD zinc finger protein Composite ... So far, the physiologic roles of the TRIP-Br proteins remain elusive Nevertheless, there are several lines of indirect but compelling evidence inferring a role for the TRIP-Br proteins in regulation ... Prominent examples of PHD zinc finger and/or bromodomaincontaining proteins The (*) label designates disease-associated PHD zinc finger and/or bromodomain-containing proteins Conservation of the...
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phosphatidylserine exposure in red blood cells: a suggestion for the active role of red blood cells in blood clot formation
... membrane proteins of RBCs can be classified into three categories Cytoskeletal proteins (α and β spectrins, protein 4.1, actin), these proteins located just beneath the lipid bilayer Integral proteins ... Aquaporins are integral membrane proteins belonging to a larger family of major intrinsic proteins that form pores in the membrane of biological cells The threedimensional structure of aquaporin ... glycophorins) are strongly embedded into the lipid bilayer Anchoring proteins (ankyrin and protein 4.2) connect with the cytoskeletal network as well as integral proteins The functions of the membrane...
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Circuit theory of finance and the role of incentives in financial sector reform
... profitability is declining The internalization of information within the same institution may thus enhance intra-circuit and inter-circuit stability by reducing the incentive to overfinancing The ... Creating a stronger investor base amounts to strengthening the circuit by completing the financial market structure of the economy, thus eliminating discontinuities in the transmission of information ... interpreting and judging are parts of the production process of information; disseminating information to the general public through reports or advertising campaigns, and providing individualized information...
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Facts of Vietnam Freight forwarding industry and the role of Vietnam Freight Forwarders Association (VIFFAS) to the industry in international economic integration processhelpful to Oristar.doc
... advantageous in serving transport in the Mekong Delta linking to Cambodia The total length of the inland waterway (IW) system is about 40,998 km, mainly in the Red River Delta and the Mekong Delta In the ... forwarding activities of the S.R of Vietnam, and on this basis to integrate with such professional colleagues on the world The Association has the role of coordinating the activities of the members ... conditions for business associations, as well implemented strategies on developing and increasing the quality of trade services of the Ministry of Trade and the Ministry of Transport Being the intermediary...
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The role of language in adult education and poverty reduction in Botswan
... English at the expense of the other languages that exist in the country, the adult language program in Botswana maintains the hegemony and the gap between the poor and the rich, the major and minority ... and the status of vulnerable groups remains precarious (Fong 1995) The major problem is that the recipients of the extension services remain uninvolved and passive in a one way flow of information ... for the betterment of their conditions It could mobilize the so called minorities to oppose their status and challenge the hegemony of the majority communities in Botswana 31 In most parts of the...
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The role of advertising in society
... categories of business-to-business advertising are industrial and professional advertising b.1 Industrial advertising Advertising targeted at individuals who buy or influence the purchase of industrial ... development of the industry also fosters the other industries in society, which contributes to the development of the economy as a whole In Vietnam, spending for advertising is rather lower than that in ... advertising industry Since the opening policy and law of foreign investment, advertising industry has seen remarkable changes The growth rate of advertising service is the highest in economy, in which...
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The role of leadership theory in raising the profile of women in management
... raising the profile of women in management However, during this period of research, there was an emerging recognition of the importance of a concern for people in the behavioural theories as being ... anything towards raising the profile of women in management, as the theory was constructed as a male model at a time when women were not visible in paid employment One of the off shoots of the ... enabling of others to help achieve the goals of the organisation Furthermore, the ability to control others is given no prominence in this recent definition of leadership A brief review of early...
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Globalization: the Role of Institution Building in the Financial Sector _ The Case Study of China
... on the securities booking system of the CGSDTC and the bond trading system of the inter-bank lending centre The trading system of the national inter-bank lending centre provides pricing information, ... source of financing for enterprises, if their own capital is excluded In summary, the deepening process of the financial markets has rendered the dominance of the banking sector in the financial ... is the processing of information The fast development of the Internet technology has influenced substantially the economic and financial behavior, and it indicates the arrival of the era of competition...
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The Role of Genetically Modified Organisms (GMOs) in Beverage Production
... throughout the world bears little resemblance to teosinte, the original ancestor of corn The newer techniques involving genetic engineering, on the other hand, allow for the transfer of a few genes in ... material The Þrst method involves enzyme-linked immunosorbent assays (ELISAs), which are based on the detection of proteins coded for by the genes inserted into GM crops These tests require minimal ... commercially introduced in the U.S in 1996 and have been rapidly adopted by farmers It has been estimated that 24% of the corn and almost 70% of the soybeans and cotton grown in the U.S in 2001 were...
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Tài liệu THE ROLE OF UNIVERSITIES IN REGIONAL INNOVATION SYSTEMS - A NORDIC PERSPECTIVE pdf
... establishment of the Faculty of Arts and the Faculty of Medicine in 1935, the Faculty of Economics and Law in 1936, the Faculty of Theology in 1942 and, finally, the Faculty of Science in 1954 The main ... the Folketing, on the role of the University as the principal shareholder in Cheminova The listing of Cheminova on the Stock Exchange in 1986 and the establishment of the first science park in ... potential of new knowledge might be biggest in the latter case The growth of the minicomputer industry in the Boston region in the 1960s and the internet industry in Silicon Valley in the1 9990s...
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Tài liệu Role of diffusion-weighted imaging in the diagnosis of gynecological diseases pdf
... satisfactory in the evaluation of nodal status in this patient group Since the highly cellular tissue in reactive lymph nodes may also show increased intensity, the role of DWI and ADC in distinguishing ... tissue in the uterine cervix and endometrium In the uterine myometrium, the ADC value may play a limited role due to the large overlap between sarcomas and benign leiomyomas The role of DWI for the ... enhancing cervical cancer (arrow) The tumor invades the cervical stroma (arrowhead) c DWI with b = 1,000 s/mm2 shows a well-defined hyperintensity mass in the cervical area The shape of the uterine...
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Tài liệu Improving health, connecting people: the role of ICTs in the health sector of developing countries ppt
... critical in ensuring the effective use of ICTs in the health sector Programme designs should consider the role of the intermediary at the same time as, if not before, the role of the technology The ... reminding them about their medication The messages can be sent in one of three languages and in a range of styles to ensure they not become boring Of the 138 patients involved in the pilot, there ... pillars: improving the functioning of health care systems by improving the management of information and access to that information, including: • management of logistics of patient care • administrative...
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