the role of oxidative stress and inflammation in dry eye disease
Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf
Ngày tải lên :
23/03/2014, 15:21
... result
from the modifications in the interactions between the
catalytic glutamates and the residues R97 and Y331,
indicating that these residues play a role in the modulation
of the Sfbgly50 pH optimum.
Sequence ... m
M
Bicine buffer 7.0–8.5). The
pH stability of Sfbgly50 was checked by incubation in the
same buffers for a time equal to the assay time and then
determining the activity remaining at the optimum ... [10,12].
Nevertheless, it is not possible to assume that the same is
occurring in the mutant R97M, because there is no data on
the interactions between the substrate and the arginine
residue.
Finally, another...
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Báo cáo khoa học: " The role of marine salt and surfactants in the decline of Tyrrhenian coastal vegetation in Italy" ppt
Ngày tải lên :
08/08/2014, 19:21
...
resistance
to
the
action
of
aerosols
is
the
result
of
the
strength
of
the
structures
protecting
the
leaf,
and
increases
with
sclerophyllia
and
with
the
thickness
of
the
cuticle.
ACKNOWLEDGEMENTS
The ...
sam-
ples
and
deposits
When
interpreting
the
results
of
the
chemi-
cal
analysis
of
rainwater
and
deposits
it
is
necessary
to
bear
in
mind
the
interactions
between
the matrix
and ...
near
the
coast
and
2-3
km
inland.
Samples
of
bulk
deposits
were
taken
from
pine
trees
(Pinus
pinea
L)
from
the
section
of
the
crown
exposed
to
the
sea
and
also
from
the...
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báo cáo hóa học: " Biomarkers of oxidative stress and its association with the urinary reducing capacity in bus maintenance workers" pptx
Ngày tải lên :
20/06/2014, 00:20
... oxida-
tive stress. The observed increase of reducing species in
urine would mirror an increased level in blood originat-
ing from a response to oxidative stress in the body mon-
itored by the urinary ... only 10% of urate is excreted in the urine (the
remaining 90% being recirculated by the renal system
[3]), an increase of this antioxidant in blood will also
lead to an increase in urine. The fact ... H,
Savant Instruments Inc.). The final volume was deter-
mined by gravimetry, assuming that the entire methanol
was removed during the conc entration in the SpeedVac
and that the d ensity of the remaining...
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Báo cáo khoa học: The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B1 and B2 bradykinin receptors potx
Ngày tải lên :
07/03/2014, 16:20
... by the amount of internalized agonist
[20]. As the internalization is expressed in percentage
of total binding, decreasing the binding affinity of the
Role of helix 8 and C-termini in bradykinin ... FEBS
The role of helix 8 and of the cytosolic C-termini in
the internalization and signal transduction of B
1
and B
2
bradykinin receptors
Alexander Faussner
1
, Alexandra Bauer
1
, Irina Kalatskaya
1
, ... addition of scintillation fluid. Nonspecific binding
was determined in the presence of 5 lm unlabeled agonist
and subtracted from the total binding to calculate the spe-
cific binding.
Internalization of...
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Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf
Ngày tải lên :
08/03/2014, 08:20
... of GSK3 (using Li or SB-415286)
appears to be sufficient for inducing activation of GS in
muscle and fat cells, and that inhibition of the kinase
potentiates insulin action in muscle of insulin-resistant ... increases in glucose uptake and glycogen synthesis
allowing for more effective ÔchannellingÕ of glucose into
glycogen in response to insulin. However, one of the
potential difficulties in interpreting ... phosphatidylinositol
3-kinase, p70, S6 kinase and glycogen synthase kinase-3 activity in
L6 muscle cells: evidence for the involvement of the mammalian
target of rapamycin (mTOR) pathway in the
L
-leucine-induced
up-regulation...
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The role of sentence stress in enhancing english speaking competence of HPU english majors
Ngày tải lên :
17/03/2014, 16:12
... Sentence stress organizes the words in the sentence into logically connected
thought groups by joining the unstressed syllables to the main stressed
syllable in the group and marking the end of the ... lose their stress. The most important words in
the sentence receive stronger stress. The last stressed word in the sentence
receives the strongest stress with the help of falling or rising intonation. ... distinguish between four levels of stress: major
sentence stress, major word stress, minor word stress and unstressed.
Thus, in the sentence: “I walked home in the rainstorm”.
‗I‘, in , and...
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- 0
Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf
Ngày tải lên :
17/03/2014, 23:20
... phenylalanine was therefore
mutated to Ala, Leu, Trp or Tyr. These mutations may
in uence the shape and volume of the acyl binding pocket
and thereby alter the binding mode and affinity of the
enzyme ... PAA and derivatives thereof, while maintaining
the hydrophobicity of the binding site.
To test the effect of the mutations on the specificity for
phenylacetylated substrates, the steady-state kinetic ... k
cat
represents
the rate of acylation and K
m
equals the binding constant of
the substrate to the free enzyme. The results then indicate
Ó FEBS 2002 Role of active-site phenylalanines in penicillin acylase...
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- 0
Báo cáo khoa học: Effect of oxidative stress and involvement of poly(ADP-ribose) polymerase (PARP) in Dictyostelium discoideum development doc
Ngày tải lên :
23/03/2014, 07:20
... discoideum to oxidative
stress, and we now show the response of this organism to oxidative stress
and the role of PARP during development. We used hydroxylamine (HA)
to induce in situ generation of H
2
O
2
and ... development.
HA-induced oxidative stress activates PARP within
5 min (Fig. 4A,B), and its role during oxidative stress
is further confirmed by the use of low concentrations
of benzamide. Preincubation of cells ... H
2
O
2
and monitored the effect of
benzamide, a PARP inhibitor, on oxidative stress- induced changes in
D. discoideum development. Interestingly, oxidative stress resulted in PARP
activation within...
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- 0
Báo cáo khoa học: Dissecting the role of protein–protein and protein–nucleic acid interactions in MS2 bacteriophage stability potx
Ngày tải lên :
30/03/2014, 11:20
... unsure of the mechanism
of DNA-induced stabilization of the protein, and whe-
ther it is related to the normal RNA-binding function
of coat protein, as RNA binding had no effect.
The increased ... understood, and we have investigated these
questions in this work. We sought to determine the
role of protein–RNA and protein–protein interactions
in virus stability, measuring the effects of urea,
GdnHCl ... against all the forms of denatura-
tion we tested. This is consistent with the observation
of increased stability of the single-chain version of the
wild-type dimer [30] and is reminiscent of the...
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- 0
Báo cáo hóa học: " An exploration of job stress and health in the Norwegian police service: a cross sectional study" docx
Ngày tải lên :
20/06/2014, 00:20
... acquisition,
analysis and interpretation of data and drafting of the
manuscript. EH was involved in design, interpretation of
data, drafting of the manuscript and supervision. ØE was
involved in conception and ... design, interpretation of data,
drafting of the manuscript and supervision. BL was
involved in analysis and interpretation of data. AMB is the
guarantor for this paper.
Acknowledgements
The study ... districts and rural ('lensman') districts. The
two categories have the same education and training, but
in the rural districts they work in smaller communities,
often including large...
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- 0
báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pptx
Ngày tải lên :
20/06/2014, 04:20
... visualized the mineralizing
cells with 2% Alizarin Red. After rinsing in distilled
water and air drying the samples, we mounted the cov-
erslips on microscope slides using Fluoromount and
examined and ... result in loss of
ambulation or limb. Here we describe the sequential roles of FGF-2 in inducing gene expression, cell growth and
BMP-2 in gene expression and mineralization of bone.
Materials and ... BMP-2, the yin and yang of mineralization:
Contrast of effect of 24 hours of treatment with FGF-2 or BMP-
2 on fold increase in abundance of mineralization-related gene
expression. Mineralizing...
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- 0
báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pdf
Ngày tải lên :
20/06/2014, 07:20
... visualized the mineralizing
cells with 2% Alizarin Red. After rinsing in distilled
water and air drying the samples, we mounted the cov-
erslips on microscope slides using Fluoromount and
examined and ... Li
4
Abstract
Introduction: The difficulty in re-growing and mineralizing new bone after severe fracture can result in loss of
ambulation or limb. Here we describe the sequential roles of FGF-2 in inducing ... BMP-2, the yin and yang of mineralization:
Contrast of effect of 24 hours of treatment with FGF-2 or BMP-
2 on fold increase in abundance of mineralization-related gene
expression. Mineralizing...
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- 0
Báo cáo khoa học: "The role of Bcl-xL and nuclear factor-kB in the effect of taxol on the viability of dendritic cells" ppsx
Ngày tải lên :
07/08/2014, 23:22
...
rationale for the use of taxol in DC immunotherapy and
insights into the development of combinational DC
therapies with other anticancer drugs that do not harm the
viability or activity of DCs.
Acknowledgments
... cells, producing major
cytokines involved in immune responses. Importantly,
taxol increased the expression of the anti-apoptotic protein
Bcl-xL, and increased the mobilization of p65 subunit ... jooh@jejunu.ac.kr
The role of Bcl-xL and nuclear factor-
κ
B in the effect of taxol on the
viability of dendritic cells
Mi-Hyoung Kim
1
, Hong-Gu Joo
1,2,
*
1
Laboratory of Veterinary Pharmacology, College of...
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- 0
Báo cáo khoa học: " Induction of oxidative stress and lipid peroxidation in rats chronically exposed to cypermethrin through dermal application" pps
Ngày tải lên :
07/08/2014, 23:22
... damage. Further significant decreases in
GSH levels in our study may be due to either the inhibition
of GSH synthesis or increased utilization of GSH for
detoxification of toxicant induced free ...
However, an increase in catalase activity enhances the
scavenging ability of erythrocytes to handle the hydrogen
peroxide to molecular oxygen and water [11,29].
GSH-Pxs catalyze the peroxides and reduce ...
significantly reduced (p ＜ 0.05) in all groups compared to
the control group. Similar finding have been reported in
other study during oxidative stress [24]. No significant
changes in GST activity was...
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- 0
Báo cáo y học: "The association of psychological stress and health related quality of life among patients with stroke and hypertension in Gaza Strip" pps
Ngày tải lên :
08/08/2014, 21:20
... characteristics of the Palestinian political and eco-
nomic situation may have contributed to these findings
indicating the significant relation of QOL and income and
education in Gaza Strip. Unemployment and ... life in these patients.
Background
Quality of life (QOL) is a phrase often used in health care
settings at policy and administration levels, in clinical
assessments of therapies, and in clinical ... the dis-
ease in the previous year, on the type of brain lesion of
stroke or the severity of the CVD condition potentially
influencing QOL were obtained. However, for the pur-
pose of this study...
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- khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản
- khảo sát chương trình đào tạo gắn với các giáo trình cụ thể
- xác định thời lượng học về mặt lí thuyết và thực tế
- tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam
- điều tra đối với đối tượng giảng viên và đối tượng quản lí
- điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1
- khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam
- khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu
- nội dung cụ thể cho từng kĩ năng ở từng cấp độ
- xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct
- phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ
- mở máy động cơ lồng sóc
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