... results in trimming the
dry branches off the bush. And this is what the
semantic type in (16) captures.
3.3 Impingement Predicates
In order to capture the semantic properties of the
arguments ofthe ... (
SOA
[ch -of- loc-rel
FIG
El
That is, as (16) above captures, in German trim-
ming necessarily results in trimming something
off something else; inthe case of example (9)
above trimming the bush ... representative verb of the
impingement predicates
class in German, the verb
schlagen
(hit) in examples (10)-(12) above, we
propose the semantic types in (17) and (18), which
are inthe spirit ofthe MRS-based...
... specific to the use of ICTs
in the health sector in developing countries. A summary of these key lessons as they relate
to intermediaries and beneficiaries, to improving the functioning of health ...
• the use of telemedicine to improve diagnosis and enhance patient care
• improvements inthe continuing professional developmentof health workers and
better sharing of research findings ... understanding and the
evidence base about the use of ICTs inthe health sector are:
• How to evaluate the impact ofthe use of ICTs on health?
• What can be done to strengthen theroleof and...
... (
39
).
The renewed interest in examining the indications for BCG vaccination in the
United States included consideration ofthe wide range of vaccine efficacies deter-
mined by clinical trials ... to
explore the sources ofthe heterogeneity inthe efficacy ofthe BCG vaccine reported in
the individual studies. Using a model that included the geographic latitude of the
study site and the data ... <5 mm induration
after skin testing with 5 TU of PPD tuberculin. The Tice strain of BCG is administered
percutaneously; 0.3 mL ofthe reconstituted vaccine is usually placed on the skin in the
lower...
... undergoes fusion with the
membrane of intra-endosomal vesicles contained within MVBs,
thereby releasing the nucleocapsid into the lumen of these vesi-
cles. Then, the capsid uses these intra-endosomal ... and mild
developmental delay. The protein defective in this disorder is also
a NHEJ protein. The distinct clinical features ofthe patients will
be discussed inthe context ofthe protein function.
3.4 ... Mutations in the
ERCC1 gene induce a distinct set of accelerated ageing features,
with a rate of onset depending on the severity ofthe mutation.
The correlation between repair defect severity and clinical...
... which appear to be involved inthe final
resorption ofthe parental macronucleus during PND
in T. thermophila, and suggested the involvement of
mitochondria in this process [19]. In mammalian apop-
tosis, ... key rolein PND in
Tetrahymena. Unfortunately, the involvement of mito-
chondria in PND has not been clarified fully. To eluci-
date theroleofthe mitochondrion as a key effector
we studied the ... directly
show the localization of mitochondria inthe autophag-
osome, as the red fluorescence corresponding to intact
mitochondria was not observed inthe area. Therefore,
to confirm further the localization,...
... go inthe same direction. The inverse is
thecasefortheattractioninthecaseofAnabaena. Also, if
the structure ofthe final complex in which electron transfer
takes place remained unaltered with increasing ... character-
ization ofthe plastocyanins has been described [1].
Representations ofthe electrostatic surfaces showing the
changes introduced by the mutations are displayed in Fig. 1.
The decay ofthe flash-induced ... interaction.
Electron-transfer chains like that of oxygenic photosyn-
thesis impose special restraints on the proteins involved.
Reactions must be fast to allow rapid turnover of the
chain. Binding between the reaction...
... 'all the present of earth vanished into the
future of Heaven, and the Kingdom ofthe Infinite arose upon the ruins ofthe finite.'
The beauty of earth was looked upon as an enchantment ofthe ... thorn.
Delight in summer, complaint of winter this is the fundamental chord struck again and again; there is
scarcely any trace of blending the feelings ofthe lover with those of Nature. It is ... and the howling of wind, the rustle of leaves, the soughing inthe tree tops, were
sounds of their presence. The worship of woods lasted far into Christian times, especially among the Saxons
and...
... imaging of
the brain was also performed in a subset of patients
in this study.
36
It was found that use of corticosteroids
possibly reduced the risk of developing
hydrocephalus and vasculitic infarcts; ... of
opportunistic infections in HIV-infected adults and
adolescents: recommendations from CDC, the National
Institutes of Health, and the HIV Medicine Association of
the Infectious Diseases Society of America. ... Vietnam. Following the
publication of this trial, Prasad and Singh
12
updated
their Cochrane systematic review on the efficacy of
corticosteroids in TBM.
12
The combined mortality in
the control...
... by the amount of internalized agonist
[20]. As the internalization is expressed in percentage
of total binding, decreasing the binding affinity of the
Roleof helix 8 and C-termini in bradykinin ... com-
prising putative helix 8, may be involved inthe inter-
action of GPCRs with cognate G proteins.
Synthetic peptides from the C-terminus ofthe G
a
subunit G
t
and ofthe Gc subunit of transducin ... addition of scintillation fluid. Nonspecific binding
was determined inthe presence of 5 lm unlabeled agonist
and subtracted from the total binding to calculate the spe-
cific binding.
Internalization of...
... stomach,
the presence of bile acids inthe intestines, and the competition against other micro-organisms inthe
gastro-intestinal tract [91,92]. The tentative ways for selection of probiotics ... cytokines, such as IL-4 and IL-10, are induced by lactobacilli
[84-85,88]. The outcome ofthe production of Th2 cytokines is thedevelopmentof B cells and the
immunoglobulin isotype switching ...
colonizing the intestine may secrete the enzyme, thus increasing the intestinal amylase activity [82,83].
It is well established that probiotics alter gastrointestinal pH and flora to favor an increased...
... by Austin
et al. [22]. In their study, the N-terminal domain of
AnfA was truncated to prevent the intrinsic aggrega-
tion ofthe intact form during purification. The
obtained variant retained transcriptional ... potential ligands of the
Fe-S cluster. Consequently, the binding ofthe ATP
analog and the subsequent rearrangement ofthe inter-
domain interaction affects the electronic condition of
the Fe-S cluster ... may reside inthe GAF
domain and the environmental factors affecting AnfA
activity remain unknown because ofthe absence of the
N-terminal domain in this variant. Because sensing is a
principal...
... distribution of BsArb43B inthe proximity
of the active site. Arabinotriose inthe binding cleft is represented
using sticks. (B) Detailed view ofthe binding cleft with arabinotri-
ose. (C) Details ofthe ... with
arabinohexose [15], this loop makes the reducing end
of the carbohydrate chain bend towards the solvent,
probably optimizing binding ofthe carbohydrate chain
in the cleft, and resulting in trioses ... for the optimal activity of
BsArb43B.
Furthermore, to determine whether theroleof the
calcium is structural, thermal shift assays were per-
formed to determine the T
m
of the protein in the...
... contrast, part
of the incorporated CFMYP is not processed to
EGMYP, enabling it to retain zinc. Indeed, 33% of
the total zinc inthe ovary at stage 1 and 13% of the
total zinc inthe testis at ... determined by ICP-AES. To investigate
the accumulation of zinc inthe gonads during gameto-
genesis, increases inthe size ofthe gonads during this period
were taken into consideration. Thus, zinc ... ofthe zinc peaks was coincident with the MYP
peak in both the ovary and the testis, indicating that
part ofthe zinc inthe immature gonads is bound to
MYP. The elution patterns of zinc were...
... FEBS 3325
Isothermal unfolding studies on the apo and holo forms
of Plasmodium falciparum acyl carrier protein
Role ofthe 4¢-phosphopantetheine group inthe stability ofthe holo
form of Plasmodium ... thrombin cleavage site was engineered in
the pET28a vector immediately after the N-terminal His-tag.
The N-terminus His-tag of ACP was cleaved by the addition
of 1 U of thrombin from bovine plasma ... obtain DG
H2O
, the
free energy of unfolding in water at temperature T.
In the first method, a single guanidine hydrochloride-
induced denaturation, where the observed CD signal at
each point in the...
... formation of MRN
foci [19–21].
The Mre11-binding domain of human Nbs1 has
been localized to amino acids 682–693 inthe COOH-
terminal region ofthe protein. Deletion of this region
of Nbs1 results in ... damage, thereby promoting
ATM-dependent signaling [23]. Domains similar to
the ATM-binding domain of Nbs1 are also found in
ATRIP and Ku80 and are required for the interaction
of these proteins with ... an NH
2
-terminally truncated
Nbs1 protein that contains an intact Mre11-binding
domain. Differences inthe nature ofthe Nbs1 muta-
tion, as well as inthe dose of radiation administered
to...