the role of natural resources and the environment in armed conflicts

... to the UN Peacebuilding Commission in assessing the role of natural resources and the environment in conflict and peacebuilding The main objective of this cooperation is to prevent natural resources ... that natural resources can be an important contributing factor in the outbreak of conflict, in financing and sustaining conflict, and in spoiling peacemaking prospects Increasing demand for resources, ... The role of natural resources and environment in conflict The role of natural resources and the environment in conflict Rationale Environmental factors are rarely, if ever, the sole cause of violent...

Ngày tải lên: 28/06/2014, 19:20

... solventaccessible All of the other cysteine residues are either buried in the skeletal structure or exposed to the internal catalytic chamber environment Therefore, we investigated whether Grx2 enters the core ... LC and HC, light and heavy chains of IgG immunoglobulin forms (cytosolic and mitochondrial matrix) [34], as the same band was seen in the anti-ubiquitin blot (Fig 7, anti-Ub) Blotting of the ... four-stranded, mixed b-sheet and five a-helices The b-sheet forms the central core of the protein, with helices and located on one side of the sheet and helices 2, and located on the other side...

Ngày tải lên: 23/03/2014, 07:20

... experiments in mice have unveiled the role of B cells in the optimal host response against MTB by increasing the infection inoculum (Vordermeier et al., 1996; Maglione et al., 2007) In addition the protection ... associated CD4 + lymphopenia observed in the present study and in other studies require further investigation to gain a better understanding of the mechanism(s) and factors involved REFERENCES Aktas E, ... lymphocyte alterations in the present study particularly the increased levels of NK and B cells in PTB patients, emphasizes the need for further investigations to evaluate their role in pulmonary tuberculosis...

Ngày tải lên: 29/03/2014, 03:20

... BMP-2 maintained the mineralizing RNA profile of igf-1, alp, and bmp-2 and significantly increased expression of other genes associated with mineralization like col1a1, fn, ilgf-1, noggin and oc ... examined and photographed the cells on a Zeiss Axioskop using 20× Tritiated thymidine incorporation into DNA At the conclusion of the 24 hour incubation, the culture medium was removed and the ... We then visualized the mineralizing cells with 2% Alizarin Red After rinsing in distilled water and air drying the samples, we mounted the coverslips on microscope slides using Fluoromount and...

Ngày tải lên: 20/06/2014, 04:20

... BMP-2 maintained the mineralizing RNA profile of igf-1, alp, and bmp-2 and significantly increased expression of other genes associated with mineralization like col1a1, fn, ilgf-1, noggin and oc ... examined and photographed the cells on a Zeiss Axioskop using 20× Tritiated thymidine incorporation into DNA At the conclusion of the 24 hour incubation, the culture medium was removed and the ... We then visualized the mineralizing cells with 2% Alizarin Red After rinsing in distilled water and air drying the samples, we mounted the coverslips on microscope slides using Fluoromount and...

Ngày tải lên: 20/06/2014, 07:20

... pretreatment with the ERK inhibitor PD98059 diminished the expression of c-Myc and mainly blocked the phosphorylation of ERK1 induced by TGF1 treatment (Figure 8b) A single isoform corresponding to phospho-ERK2 ... TGF1 These data indicate that the inhibition of cMyc transcriptional activity diminished the level of c-Myc protein itself and also downregulated the phosphorylation (activation) of ERK1/2 The ... response to Myc binding differs markedly according to context and cell type [55] The elucidation of the role of c-Myc in ERK1/2 phosphorylation in nucleus pulposus cells requires further investigation...

Ngày tải lên: 09/08/2014, 01:22

... thermistor probe was inserted subcutaneously in the right leg, and the hind limb temperature was monitored and maintained at 36 ± 1°C After the ischemia period, the bands were removed and the mice allowed ... An overview of mast cell content in the four groups of mice tested was obtained by counting a minimum of 100 mast cell profiles in tongue, skin and heart as well as skeletal muscle Using 100 X ... variation in the period of ischaemia, the muscle temperature during ischaemia and the period of reperfusion allowed for manifestation of the reperfusion injury Idstrom [12] utilised a period of 2, and...

Ngày tải lên: 11/08/2014, 08:21

... cyclin binding motifs, one at the N- and the other at the C- terminus [20] p21/waf1 (mut) is mutated at the N-terminus and is therefore still able to bind to cyclins through the C-terminus, making ... terminus and the other at the C terminus [20] p21/waf1 interacts with both cyclins and cdks, in contrast to the INK family CDKI members, which only bind to cdks [20] Interestingly, p21/cyclin ... represents the nucleolus, whereas the lighter blue staining represents the nucleoplasm As expected, the intensity of staining for cyclin D2 and p21/ waf1 was increased in HTLV-1 infected T-cells When the...

Ngày tải lên: 13/08/2014, 13:20

... licensed in the United States and other parts of the world for this purpose There is significant off-label use of rFVIIa in surgical applications including uncontrolled bleeding in the operating room ... concerning in recent discussion regarding the use of rFVIIa in the setting of injury is a potential role for this material in magnifying early traumatic coagulopathy Administration of rFVIIa in supraphysiologic ... derivative of the aminoacid lysine which inhibits fibrinolysis by blocking the lysine binding sites on plasminogen Fifty-three studies including 3,836 participants have involved tranexamic acid in patients...

Ngày tải lên: 13/08/2014, 23:20

... phosphorylated and processed into p52 The processing of p100 to p52 results in the loss of the ankyrin repeats in the C-terminus and allows translocation of the RelB/p52 dimers into the nucleus ... Binding of the p65/p50 dimer results in IκBα resynthesis and IκBα is then exported back to the cytoplasm, binding NF-κB and inactivating the pathway Protein phosphatase 2A is a key regulator of ... been added with the division of the luminal subtype into luminal A and B, and the inclusion of the claudin-low subtype [50-51] Both the luminal A and B subtypes show expression of ER, PgR or ER...

Ngày tải lên: 22/12/2014, 21:49

... ties In investigating the role of social ties in the recruitment of participants for social movements, scholars have investigated the effects of each type of network—formal and informal in influencing ... perception of others and the nature of the collective identity shared with other political bloggers in Singapore; the nature of their participation in activism; their relationships (or lack thereof) ... both individual and structural factors, as well as the mediating process between them, of which the most important were identification and structuring of the superego, and the role of media in...

Ngày tải lên: 10/09/2015, 15:52

... Chapter Introduction Figure 1.1: The extrinsic and intrinsic pathways of caspase activation and apoptosis The extrinsic pathway involves oligomerization of death receptors by their ligands, resulting ... cancerous cells In the case of the IL-1 and TNF cytokine, interaction of these cytokines to their respective receptors on the cancer cell activates downstream signaling components of the NF-κB pathway, ... which in turn activates the IKK1 and IKK2 (Poyet et al., 2000), resulting in the auto-phosphorylation of IKK via the T loop serine residues, serine 177 and 181 within the activation loop of the...

Ngày tải lên: 14/09/2015, 08:45

... brain injury and severe hemorrhage During traumatic brain injury (Sinz et al., 1999) and hemorrhagic shock (Szabo and Billiar 1999, Shinoda and Whittle, 2001), there is induction of iNOS The iNOS ... production of PGs On the other hand, COX-2 is an inducible isoform that is induced by cytokines, mitogens, and endotoxins in inflammatory cells and is responsible for the elevated production of PG during ... conditions, including traumatic brain injury (Wada et al., 1998) and P PPP hemorrhagic shock (Hua and Moochhala, 1999) The role of NO in maintaining homeostasis (Ambrosio et al., 1998) and regulating...

Ngày tải lên: 16/09/2015, 15:54

... shock model: the role of NO and angiotensin II and the therapeutics effects of conservative fluids, NOS donor and inhibitors Paper Chapter 6: Role of NOS inhibitors in rats following combined fluid-percussion ... and eosin stain of Kidneys 62 Figure 4.4.2 Hemotoxylin and eosin stain of Lungs 63 Figure 4.4.3 Hemotoxylin and eosin stain of Livers 64 Figure 4.4.4 Hemotoxylin and eosin stain of Cerebral cortex ... fluids, NOS and COX-2 inhibitors Role of angiotensin II in prolonged hemorrhagic shocked rats and therapeutic effects of conservative fluids and NOS inhibitors Role of NOS inhibitors in a combined model...

Ngày tải lên: 16/09/2015, 15:54

... 031879.1) and AMOs (AMO-1 and AMO-133a) were synthesized by Jima Inc (Shanghai, China) The sequences of miRNA mimics and AMOs are showed in Table Mimic and AMO of miRNA pretreatment in vivo Mimic and ... with lipofectamine 2000 (Invitrogen), was injected into the myocardium Ten sites were selected on the LV anterior wall for intramuscular injection The chest was closed after injection and the rat ... 6) IPost regulates the protein expression of CASP9 To determine the effect of IPost on CASP9 protein during IR, the protein expression of CASP9 in different groups was determined by Western blot...

Ngày tải lên: 10/08/2014, 05:21

... Rho-kinase U-0126, indomethacin (indo) and Y-27632 are inhibitors of MAPK, COX and Rho-kinase, respectively experiments HM participated in the design of the study and the interpretation of the ... of Rho-kinase inhibition on prostaglandin-induced contraction Effects of Rho-kinase inhibition on prostaglandin-induced contraction PGE2 (A) -and PGF2α (B)-induced contraction in the absence and ... participated in the design of the study, interpretation of results and final revision of the manuscript SAN supervised the study, participated in its design and in the preparation of the manuscript...

Ngày tải lên: 12/08/2014, 18:22

... Contents 2.2.4 The principle of the exploration and use of outer space for the benefit and in the interest of all countries, and the ‘province of all mankind’ concept 23 2.2.5 Article II of the Outer ... The principle of the exploration and use of outer space for the benefit and in the interest of all countries, and the ‘province of all mankind’ concept The three rights (to free access, of exploration ... l’espace, in J ournal d u Dr oit international, (1968), p 533; M W illiams, The Exploration and Use of Natural Resources in the Law of the Sea and the Law of Outer Space, in Proceedings of the Twenty-Ninth...

Ngày tải lên: 30/03/2014, 02:20

... overwhelming fraction of resources, located in the South, are used up in the North, in Introduction the industrialized countries, and the North has become the strongest polluter of the global environment ... rate of private consumption falls as a result of the increase in the tax rate τp and then continues to decline gradually (since h declines) as the new BGP is approached The impact of a rise in ... growth effect of a higher pollution tax revenue (i.e., the increase in the creation of the stock of public capital) is dominated by the negative indirect effect of a reduction of the rate of return...

Ngày tải lên: 10/06/2014, 21:48