Ngày tải lên: 12/08/2014, 04:20
... near the flexible C terminus of SNase. Changes in the fluorescence intensity of W140 reflect a change in the surrounding hydrophobic environment of the tryptophan and thus indicate a change in the overall ... (E75G) lower than that of the wild-type protein, suggesting that Glu residues at positions 75 and 129 play key roles in maintaining the native structure of the protein. Furthermore, two mutants, ... exists in these mutants (Fig. 1). Thermal analysis of protein unfolding Thermal denaturation determined by DSC was used to measure the stability of the mutant proteins. Based on the measurements of...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage potx
... presence of ionizing radiation [12], and in the present study, in the absence and the presence of cisplatin. In addition, we showed that Pph3p directly or indirectly binds to cH2AX, indicating that ... hypersensitivity to the antitumour drug cisplatin, indicating that all three proteins may oper- ate as a functional unit in vivo, playing a role in the cisplatin response [9]. Cisplatin interferes with ... Substitution of the H2AX Ser129 by Ala restored the ability of the pph3D strain to turn off checkpoint signalling in a timely manner and re-enter the cell cycle after DNA repair of the double-strand...
Ngày tải lên: 30/03/2014, 04:20
the role of ''too big to fai'' status in bank merger activity
... the failure of the bank would undermine the financial stability of the economy. Only then would the FDIC be entitled to protect all the liabilities of the bank against loss. Further, enacting ... maximize profits at the point where the marginal cost of raising funds equals the marginal benefit from using those funds. Deposit insurance affects the analysis by shifting the marginal cost ... that the government safety net removed the oversight role of the market in assessing the risk of banking institutions. The moral hazard created by the safety net enables banks to increase the...
Ngày tải lên: 03/06/2014, 02:17
báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pptx
... BMP-2, the yin and yang of mineralization: Contrast of effect of 24 hours of treatment with FGF-2 or BMP- 2 on fold increase in abundance of mineralization-related gene expression. Mineralizing ... reduce the relative abundance of a majority of the mineralizing-associated genes.ThedramaticreductionofIGF-1byFGF-2sug- gests a role for IGF-1 in minera lization, this is i n agree- ment with findings ... visualized the mineralizing cells with 2% Alizarin Red. After rinsing in distilled water and air drying the samples, we mounted the cov- erslips on microscope slides using Fluoromount and examined...
Ngày tải lên: 20/06/2014, 04:20
báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pdf
... reduce the relative abundance of a majority of the mineralizing-associated genes.ThedramaticreductionofIGF-1byFGF-2sug- gests a role for IGF-1 in minera lization, this is i n agree- ment with findings ... to heal the defect. The increase in cell replication in a miner- alizing cell likely represents a de-differentiation from th e mineralizing phase to the growing phase, and increases expression of ... BMP-2, the yin and yang of mineralization: Contrast of effect of 24 hours of treatment with FGF-2 or BMP- 2 on fold increase in abundance of mineralization-related gene expression. Mineralizing...
Ngày tải lên: 20/06/2014, 07:20
báo cáo hóa học:" Impact of recent life events on the health related quality of life of adolescents and youths: the role of gender and life events typologies in a follow-up study" potx
... be part of a risk group. In addition, the combination of these two LEs seems to be usual. In fact,notonlytheLCUssumscoredeterminetheeffect, it’s the undesirab ility of thes e LEs what makes respon- dents ... measures of LEs in order to take into account also their effect in previous HRQoL. Conclusions The experience of LEs did impact the HRQoL of adoles- cents and youths in this sample, although the effect ... method in order to address the multiple testing problem. The decision rule is to reject the null hypothesis when the adjusted p-value is les s than a = 0.05[39]. To investigate the first aim of the...
Ngày tải lên: 20/06/2014, 16:20
Báo cáo khoa học: "the Role of Non-Timber Forest Products (NTFPs) in Livelihood Strategies and Household Economies in a Remote Upland Village in the Upper Ca River Basin, Nghe An, Vietnam" pdf
... nearby, these are the main source of medicine in the hamlet. A diverse array of medicinal plants is gathered year round, and most households also used medicinal plants to purify daily drinking ... sources of income. The roles of NTFPs in Que seemed less important than those in Tha Lang, although cash income from NTFPs in Que was much higher. The reason for this was the better access to the ... analysis running SPSS software presents that the 29 remaining households can be divided into four clusters. The indicators in clusters show that all of these households seem to follow the extensive...
Ngày tải lên: 06/08/2014, 19:20
Báo cáo lâm nghiệp: "The role of Hylastes cunicularius Erichson (Coleoptera: Scolytidae) in transferring uropodine mites in a mountain spruce forest" pptx
... overlooked in mountain spruce forests in the Tatra Mountains and, possibly in other mountain areas in Europe too. In the study area, the bark beetle acts as a vector of at least four species of uropodine ... from 0.064 in the valley Bielovodská dolina to 0,108 in Tomanova dolina and 0.145 in Velická dolina, giv- ing the value of 0.103 for the study area as a whole. The rarefaction curve of the pooled ... 261 5.8% in the valley Velická dolina (N = 695), 17.6% (N = 2,204) in Tomanova dolina and 24.6% (N = 403) in Bielovodská dolina. Of the 3,302 individuals of H. cunicularius sampled in the study...
Ngày tải lên: 07/08/2014, 03:22
Báo cáo y học: "The role of mast cells and fibre type in ischaemia reperfusion injury of murine skeletal muscles" pot
... to determine the usefulness of ther- apies against mast cells, it is important to know the degree to which mast cells are involved in IR injury of other skel- etal muscle fibre types. In this ... variation in the period of ischaemia, the muscle temperature during ischaemia and the period of reperfusion allowed for man- ifestation of the reperfusion injury. Idstrom [12] utilised a period of 2, ... IR injury than the slow/fast- and fast-twitch muscles. Data from other studies are diffi- cult to compare because of the wide variety of IR models in use. In particular, there is a great deal of...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: " The World Trade Center Attack Helping the helpers: the role of critical incident stress management" potx
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "What is the role of surfactant and inhaled nitric oxide in lung transplantation" pps
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: " The role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cells" potx
Ngày tải lên: 13/08/2014, 13:20
gjerstad & smith - rethinking housing bubbles; the role of household and bank balance sheets in modeling economic cycles (2014)
Ngày tải lên: 01/11/2014, 18:18
the role of ikkalpha, ikkbeta and nf-kappab in the progression of breast cancer
Ngày tải lên: 22/12/2014, 21:49
báo cáo hóa học:" Functional significance of the signal transduction pathways Akt and Erk in ovarian follicles: in vitro and in vivo studies in cattle and sheep" ppt
... Effects of active immunization of sheep against an amino terminal peptide of the inhibin αC subunit on intrafollicular levels of activin A, inhibin A and follistatin. Journal of Endocrinol- ogy ... Our findings suggest that Akt is important in mediating the effects of FSH on inhibin-A, activin-A, oestradiol and progesterone secretion and also important in mediating IGF-I stimulated inhibin-A, activin-A, ... assess the equal transfer of the proteins from the gel to the mem- brane. TBS-Tween was used to destain the membrane, which was then blocked in 5% Marvel in TBS-Tween for 1–2 h. The blocking solution...
Ngày tải lên: 20/06/2014, 07:20
Báo cáo khoa học: "The role of leadership in overcoming staff turnover in critical care" pptx
Ngày tải lên: 12/08/2014, 22:22
Circuit theory of finance and the role of incentives in financial sector reform
... capital profitability is declining. The internalization of information within the same institution may thus enhance intra-circuit and inter-circuit stability by reducing the incentive to overfinancing. The ... placing money with investment financial institutions in the capital market, and hold the remaining share in non- interest bearing, short-term bank deposits (eq. 7). The share of savings going ... Banks thus increase lending to the point where the marginal revenue from lending equals the marginal default risk. The amount lent determines the amount of inputs that firms can purchase in the factor...
Ngày tải lên: 24/10/2012, 09:33