the role of civil society organisations in regulating business

... University Regional Learning Alliance – workforce development and training/collaborations with business and industry; meeting the training and education needs of businesses within 60 mile radius in Northern Allegheny ... and Initiatives Business accelerators and/or entrepreneurial initiatives Linking teaching and research to business opportunities Collaboration with local business and industry Small Business ... opportunities Shippensburg University Small Business Initiative in the Frehn Center for Management; offering information and assistance to individuals and groups planning to start a new business Indirect Contributions...

Ngày tải lên: 21/02/2014, 01:20

... designed on the basis of side-chain packing criteria from a modelled structure of the enzyme resulted in restor- ation of the energy of activation to the levels of the native enzyme and in an increased ... flexibility limits the exploitation of the full potential of protein engineering in the redesign of psychro- philic enzyme properties [15]. In particular, the effects of local flexibility in psychrophilic ... respectively. By introducing an Ala residue in the place of Gly it is expected that the conformational flexibility of the main chain can be constrained with a minimum perturba- tion of the local structure,...

Ngày tải lên: 22/02/2014, 04:20

... antigen in itself [7,20]. At least for these antibodies, the role of the V L domain might be to increase the affinity by supporting the V H domain. The phenomenon may also be observed in the chain ... Although the Fv was designed based on HyHEL-10, it is not clear whether or not H39 is dominantly tuning the V H ⁄ V L interaction of other Fvs, including HyHEL-10. In addition, the effect of the H39 ... clarify the effect of the interface mutations on the antigen- binding affinity. To investigate systematically this unsought relationship between the antigen-binding affinity of Fv and the V H ⁄ V L interaction...

Ngày tải lên: 07/03/2014, 12:20

... example, in the case of question Q209: “Who invented the paper clip ?”, the expected answer type is PERSON and so is the subject of the verb invented , lexicalized as the nominalization inventor. ... mountain; (b) lava IS-PART of vol- cano, and moreover it is a part coming from the inside; and (c) fragments of lava have all the prop- erties of lava, the following question semantic The Role of ... “Where did the ukulele originate ?”, the expected answer type is LOCATION. In the paragraph the ukulele intro- duced from Portugal into the Hawaiian islands” contains two named entities of the category...

Ngày tải lên: 08/03/2014, 05:20

... their brand attitude, may suggest an interesting implication for the new brand advertising strategy. Instead of focusing on the content of the message which only emphasizes the benefits of ... gift giving is instrumental in maintaining social ties and serves as a mean of symbolic communication in social relationship. Most of the researches before and after the appearance of Sherry’s ... described in details the stages of the whole gift- exchange processes, researchers have examined the influence of many variables within these stages. This model divides gifting activities into...

Ngày tải lên: 14/03/2014, 14:20

... school. Conley (2001) finds that a doubling of net worth results in an 8.3% increase in the probability of attending college. Further, when net worth is included in the model, Black youth are ... youth. Youth savings. Youth were asked in 2002 whether they had a savings or bank account in their name. If they had an account, they were also asked whether they were saving some of this money ... ―very concerned‖ about the cost of college, compared to 19% of high-income parents. Further, they find that 71% of low-income youth say they are very concerned about the cost of college (ACSFA,...

Ngày tải lên: 15/03/2014, 10:20

... that the increase of Glc6P in the presence of S4048 was caused by the inhibition of Glc6P hydro- lysis in the absence of detectable changes in glucose phosphorylation. S4048 causes inactivation of ... glu- cokinase and hexokinase I in distinct pools [3,24], or by the involvement of mechanisms, additional to Glc6P, in mediating the effects of glucokinase over- expression. As glucokinase binds ... as expected from the dual role of Glc6P in regulating both of these enzymes (Fig. 1). The selectivity of the effects of S4048 (at < 2 lm) was further supported by its lack of effect on phosphorylase-a...

Ngày tải lên: 16/03/2014, 14:20

... documents and find that the fea- ture vectors corresponding to some of these docu- ments (particularly the short ones) have all zeroes in them. In other words, none of the bigrams from the training set ... cap- turing two different situations, one in which the author himself likes the movie, and in the other, the author’s cousin likes the movie. The over- generalization resulting from these “stemmed” ... available. 612 Proceedings of the COLING/ACL 2006 Main Conference Poster Sessions, pages 611–618, Sydney, July 2006. c 2006 Association for Computational Linguistics Examining the Role of Linguistic Knowledge...

Ngày tải lên: 17/03/2014, 04:20

... tight binding affinity was demonstrated towards lauric acid, resulting in the synthesis of mainly x-1 hydroxylated lauric acid, suggesting a role in the lipid oxidative metabolism. Interestingly, the ... occurring in the soil. Furthermore, branched chain fatty acids make up 80% of the fatty acid content of the Bacillus sp. mem- branes and when the hydroxylation of these substrates was studied in ... enzymes. The FUM6 protein (CYP505B1) inter- venes in one of the first steps in fumonisin synthesis by hydroxylation of the polyketide-amino acid at C-14 and C-15 (Fig. 3). Fum6 deletion mutants of F....

Ngày tải lên: 22/03/2014, 16:21

... the transaction from the vantage point of firm A, the floating- rate payer. The cost of synthetic floating-rate financing is determined by the cost of servicing fixed-rate debt plus the net cost of ... to the desire on the part of firms to hedge cash flows against the effects of interest rate volatility. The timing of the appearance of interest rate swaps, coming as it did during a pe- riod of ... argue, trading in interest rate swaps has helped to complete forward markets and to lower the cost to firms of managing their exposure to interest rate risk. The Role for Hedging in the Theory of Corporate...

Ngày tải lên: 22/03/2014, 17:20

... rapidly, causing the unfolding of one of the I27 modules in the chain. Unfolding then extends the over- all length of the protein, relaxing the pulling force to a low value. As the slack in the length ... stretching a polyprotein re- sults in a well-defined series of step increases in length, mark- ing the unfolding and extension of the individual modules in the chain. [37] The size of the observed steps ... b-strands of the I27 protein during the main unfold- ing barrier. [39] To further validate this view and gain insight into the role of solvent hydrogen bonds in protein unfolding, we repeated these...

Ngày tải lên: 22/03/2014, 18:20

... the preservation of the individual, while they continue to operate in the manner of instinctive desires; are nearly the same in man that they are in the other animals; but in him they are sooner or ... err in computing the miseries of men, from the measures of trouble and of suffering they seem to incur. And if there be a refinement in affirming that their happiness is not to be measured by the ... arise in the struggles, the triumphs, or the misfortunes of a tender affection. The death of Polites, in the Aeneid, is not more affecting than that of many others who perished in the ruins of Troy;...

Ngày tải lên: 23/03/2014, 17:20

... maintained in multiple accounts within the organisation. The organisation is in some sense wasting resources and duplicating efforts in maintaining separate profiles with (mostly) the same information. ... take into account in the assessment of the security risks to − and privacy impact on − the delivery of online services, and in determining appropriate levels of security.  In the case of sensitive ... managing and protecting digital identities, with a view to strengthening confidence in the online activities crucial to the growth of the Internet Economy. The primer is a product of the Working...

Ngày tải lên: 23/03/2014, 23:21

... dur- ing lipid raft isolation. Moreover, these studies have provided some insights into the significance of the localization of the P2X 7 receptors in lipid rafts regard- ing the regulation of intracellular ... (glycero-)sphingolipids. In addition the fatty acid chains of the phospholipids composing these rigid domains are generally more saturated than those in the lipids of the surrounding membrane. In fact, this ... muscarinic receptors, endo- thelin receptors, rhodopsin) are located in lipid rafts [65–70] where they are in close proximity to their transducing GTP-binding protein (Gs, Gi, Go, Gq and transducin...

Ngày tải lên: 30/03/2014, 02:20

... suggested by the lack of coincidence of the changes in relative fluorescence intensity and in  k and by the hysteresis of the reversibility process (Fig. 4). At the end of the transition, the intrinsic ... that of the wild-type; however, the integrity of the calcium bind- ing site formed by Asp287 and Glu53 is essential for interaction with the cation in 7.9 m GdmCl. An interesting finding of the ... pfLamA in the native state, indepen- dently of their interaction with calcium. The role of electrostatic interactions in protein stability has been widely investigated and the stabilizing effect of...

Ngày tải lên: 30/03/2014, 04:20

Ngày tải lên: 30/03/2014, 13:20

Ngày tải lên: 30/03/2014, 14:20

Ngày tải lên: 30/03/2014, 16:20

Ngày tải lên: 08/04/2014, 18:33

Ngày tải lên: 18/06/2014, 17:20