... preparations. The role of histi- dine in metal ion coordination in MTs is a subject that has gathered increasing importance in the field, especially because the 3D structure of the Zn and Cd complexes ... (Uniprot P17512). The coordinat- ing and putative coordinating residues are highlighted (Cys in grey shadow, His and Tyr in bold) and the total content in each peptide is indicated. The initial GS residues ... elements for their metal binding behavior. With respect to CeMT1, the data suggest the contribution of three out of four histidines (prob- ably excluding the C-terminal histidine) in the coordi- nation
Ngày tải lên: 07/03/2014, 02:20
... acetyl-lysine binding modules present in ATP-dependent chromatin remodelling factors as well as in some HATs and other nuclear protein s of unknown function [89]. B romodomain-containing proteins therefore appear ... Lys-Thr/Ser pairs found in the four histones may negatively regulate the binding of chromodomains to methylated lysines. Indeed, chromo- domain-containing proteins are involved in a variety of functions, ... characterized in the mouse [10] as well as in the rat [12]. In situ hybridization detects the RNA in mid-pachytene s permatocytes, a nd immunodetection indi- cates the presence of the p rotein from the
Ngày tải lên: 07/03/2014, 16:20
The Role of Theory in Aesthetics ppt
... "art" in the others as well. The essence of painting, they maintain, are the plastic elements in relation. Its defining property is significant form, i.e., certain combinations ... since these are indigenous to painting. Thus, the role of the theory is not to define anything but to use the definitional form, almost epigrammatically, to pin-point ... THEORY IN AESTHETICS* MORRIS WEITZ Theory has been central in aesthetics and is still the preoccupation of the philosophy of art. Its main avowed concern remains the determination
Ngày tải lên: 07/03/2014, 17:20
The Role of Probiotics in the Poultry Industry doc
... of the gut, and it must be able to adhere to the intestinal epithelium to overcome potential hurdles, such as the low pH of the stomach, the presence of bile acids in the intestines, and the ... biotechnology in poultry nutrition is of significant importance. Biotechnology plays a vital role in the poultry feed industry. Nutritionists are continually putting their efforts into producing better ... competition against other micro-organisms in the gastro-intestinal tract [91,92]. The tentative ways for selection of probiotics as biocontrol agents in the poultry industry are illustrated in Figure
Ngày tải lên: 08/03/2014, 09:20
The Role of Brand In Your BusinessBy Jay Abraham© 2003 potx
... important to building the brand There’s a saying in. .. want Whether they trust in their dealings with you, they trust in the construction of the product, they trust in the promise ... building the personality, the dimension, the interconnection between your brand and the consumer, the greater the connection, the greater the bond, the greater the loyalty, the greater the sales, ... manufacturers in Beijing China. These are the notes of my talk, reformatted for you so that they are much easier to follow. The core of the speech centered around building, maintaining and sustaining
Ngày tải lên: 14/03/2014, 19:20
The role of pictures in improving health communication: A review of research on attention, comprehension, recall, and adherence doc
... mean- ingless. Readers may then use the picture to guess the intended meaning, often incorrectly, and think that they understand the message, thereby interfering with their comprehension. They ... medicine including how many pills to take at a time and when to take the pills. One of the instruction sets was just words and the other was words plus a drawing that integrated the pill taking instructions. ... of animated cartoons explaining the need for a polio vaccine. The information contained in the videotape was the same as in the leaflet. Both versions were available in English and Spanish. Subjects
Ngày tải lên: 14/03/2014, 21:20
Beyond Remittances: The Role of Diaspora in Poverty Reduction in their Countries of Origin pptx
... even the major player, in attracting Diaspora investors Writing of investment from Taiwan into mainland China, Hsing makes the point that the partners to the overseas Chinese investors in many ... patterns China The Chinese Diaspora originated in the sea-faring communities of the southern coastal provinces and the trading outposts they established in the littoral cities of Southeast Asia ... of origin is, in the overwhelming majority of cases, the creation of individuals and groups acting on their own initiative, rather than a product of government intervention Beyond the individual
Ngày tải lên: 15/03/2014, 09:20
The Role of Districts in Fostering Instructional Improvement pptx
... lead instructional reform • Instituting... databases Findings Our evidence yielded the following findings District Instructional Improvement Strategies In the three districts, instructional ... ex- amined district reform efforts in four areas: promoting the instructional leadership of principals; supporting the professional learning of teachers, in particular through school-based coaching models; ... coaching models; specifying curriculum; and promoting data-based decision- making for planning and instructional improvement. We also exam- ined the impact of the IFL on these instructional improvement efforts. This
Ngày tải lên: 15/03/2014, 23:20
Báo cáo khoa học: New evidence for the role of calcium in the glycosidase reaction of GH43 arabinanases pot
... with arabinohexose [15], this loop makes the reducing end of the carbohydrate chain bend towards the solvent, probably optimizing binding of the carbohydrate chain in the cleft, and resulting in trioses ... for the optimal activity of BsArb43B. Furthermore, to determine whether the role of the calcium is structural, thermal shift assays were per- formed to determine the T m of the protein in the ... BsArb43B in the proximity of the active site. Arabinotriose in the binding cleft is represented using sticks. (B) Detailed view of the binding cleft with arabinotri- ose. (C) Details of the residues
Ngày tải lên: 15/03/2014, 23:20
Báo cáo khoa học: The role of Tyr71 in Streptomyces trypsin on the recognition mechanism of structural protein substrates ppt
... for arginine and lysine at the P1 position and proline and glycine at the P2 and P3 positions [28]; neither of these residues, espe- cially proline, is preferred by other human cathepsins. Previously, ... GGA and GGG, leucine was substituted with tyrosine, phenylala- nine, tryptophan, alanine, glycine, arginine, histidine, aspar- tic acid, asparagine, serine and proline, respectively. The amplified ... protein–collagen complex. Because the molecular size and structure of trypsin- like serine proteases and these collagenases differ, the domain corresponding to the CBD remains elusive. Nevertheless,
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: The role of DYRK1A in neurodegenerative diseases docx
... proteins, including transcription factors, phosphor- ylated by DYRK1A, indicates that DYRK1A overexpression is central for the deregulation of multiple pathways in the developing and aging DS brain, ... proteins). In all exam- ined subregions of brains of DS subjects, the level of DYRK1A is higher than in control brains, but with an increase that varies topographically from 25 ngÆmg )1 in the ... ngÆmg )1 in the temporal cortex, 20 ngÆmg )1 in the occipital cortex, to only 15 ngÆmg )1 in the cerebellar cortex [14]. Striking brain structure-specific and neuron type-specific differences in the
Ngày tải lên: 22/03/2014, 16:21
The Role of Deployments in Competency Development - Experience from Prince Sultan Air Base and Eskan Village in Saudi Arabia potx
... deployment within the preceding 12 months Respondents selected from a list of settings all those settings in which they learned a specific competency or skill They then indicated the single ... then indicated the single “best” learning environment for the skill or competency in question Settings included initial training, on -the- job training (OJT)/normal duty assignments, schoolhouse, ... throughout the survey and in one final open-ended question The actual - 7 survey instrument, including instructions and DAL competency definitions, is provided in the appendix
Ngày tải lên: 23/03/2014, 01:20
The Role Of Exhibitions In The Marketing Mix pot
... participating in trade fairs. The content is structured as follows: In Chapters I general information about trade fairs and the exhibition industry is presented (definitions, integration into the ... those industries authorized to the show. The typical buyer is an industrial end user, or another distributor, within the industry segment hosting the exposition. Attendance is restricted to these ... representing the market segment initiate the trade show or are invited to become partners of the exhibition... In addition to the already existing exhibition facilities, the Singapore
Ngày tải lên: 23/03/2014, 04:21
The role of poultry in peoples livelihoods in Uganda pot
... that the birds would not eat all the grain The. .. Livelihoods The role of poultry in people’s livelihoods in Uganda 26 the study findings, the buying and selling of ... practice is the killing... into the findings of the survey analysis These interviews involved local leaders, opinion leaders, district staff, significant farmers involved in animal production, ... For the sector to play its role effectively, it should be incorporate into the National Development Plan – NDP, as well as including it in the sector investment plan of MAAIF. Finally, there
Ngày tải lên: 23/03/2014, 21:20
Working PaPer SerieS no 967 / november 2008: Central bank miSPerCePtions and the role of money in interest rate rules pptx
... to maintaining the disinflationary stance implied by the policy with cross-checking for a finite number of periods, T , in the future In this case, the central bank is able to in? ??uence future in? ??ation ... similar to the baseline case discussed in the paper concerning the success of cross-checking in offsetting the in? ??ationary bias due to persistent central bank misperceptions Of course, due to the response ... banking practice Money supply measures play no role in the estimation, testing or policy simulation of these models A role for money in the long run is sometimes verbally acknowledged, but the
Ngày tải lên: 29/03/2014, 13:20
THE ROLE OF GOVERNMENT IN ECONOMIC DEVELOPMENT potx
... untargeted It intervened most directly in the least developed late-comers, by financing investment itself, by targeting these investments to branches of industry... the factor explaining the ... favoring the influx of unskilled labor. Where the country was too poor to finance the banks required to finance industry, the state promoted the establishment of financial intermediaries, invested ... even in Great Britain and the United States, where the direct economic role of governments was least, governments played a pivotal role in promoting the industrial revolution. By 1870 in the United
Ngày tải lên: 31/03/2014, 05:21
the role of location in the marketing strategy of performing arts organizations
... declining financial support from... determine the relative importance of location in the marketing strategy More specifically the research seeks to investigate the following themes: ... contributed insight to my research by offering useful comments at the preliminary stage of my research and for the knowledge they imparted during the coursework stage of my studies. The following ... professionals provided invaluable guidance. The insight and knowledge of the performance arts industry of Randall Kramer played a key role in the development of my survey instrument, the foundation
Ngày tải lên: 03/06/2014, 02:17
báo cáo hóa học:"The role of disclosure in relation to assent to participate in HIV-related research among HIV-infected youth: a formative study" docx
... told at the beginning of the research. Their rea- sons focused on reducing the children being taken aback upon learning their status during the course of the research and for enhancing the children's ... whether or not disclosure should be a component of the research, being mindful that the minors participating in the research may in fact want to know that they have HIV. Participation in the ... Boards at the Kinshasa School of Public Health in the DRC and at the University of North Carolina at Chapel Hill in the US. All participants in the formative research provided their written informed
Ngày tải lên: 20/06/2014, 08:20
AUTISM SPECTRUM DISORDERS: THE ROLE OF GENETICS IN DIAGNOSIS AND TREATMENT pot
... established the initial rapport with the family in the waiting room, introduces the family members to the counselor, enters the room and participates in the genetic counseling process Everyone sits in ... about the dynamics of the process and the benefits they might obtain with the clearing up of their doubts and specific guidance The father rejected obstinately attempts of contact and the mother ... Disorders: The Role of Genetics in Diagnosis and Treatment on the Internet many details about the problem and were very shocked and confused In the waiting room the psychologist explained to them about
Ngày tải lên: 28/06/2014, 05:20
The Role of Brand In Your Business By Jay Abraham pot
... important to building the brand There’s a saying in. .. want Whether they trust in their dealings with you, they trust in the construction of the product, they trust in the promise ... building the personality, the dimension, the interconnection between your brand and the consumer, the greater the connection, the greater the bond, the greater the loyalty, the greater the sales, ... manufacturers in Beijing China. These are the notes of my talk, reformatted for you so that they are much easier to follow. The core of the speech centered around building, maintaining and sustaining
Ngày tải lên: 28/06/2014, 12:20