the process of regulatory review for new cardiovascular devices

... Suppose that for each x Î X kp(y, Ty) ≤ ϕ(p(x, y))p(x, Ty) for all y ∈ Tx (3:9) Then F (T) = ∅ Proof Since k ≥ 2, (3.9) implies (3.1) Therefore, the conclusion follows from Theorem 3.1 The following ... 100-2115-M-017-001 of the National Science Council of the Republic of China Author details Department of Mathematics, Honghe University, Yunnan 661100, China 2Department of Mathematics, National ... to verify that for each x Î X, 2p(y, Ty) ≤ ϕ(p(x, y))p(x, Ty) for all y ∈ Tx Therefore, all the assumptions of Theorem 3.1 are satisfied, and we also show that F (T) = ∅ from Theorem 3.1 He...

Ngày tải lên: 20/06/2014, 22:20

... requested by the FSA prior to the FSA’s on-site review of the application This reflects the need for the FSA to have all the relevant documentation in order to conduct the desk based review of the application ... the industry forums for UK regulated covered bonds 2.2 Box 2.A provides a summary of the key features of the UK regime These are discussed in detail in the rest of this Chapter 2.3 The UK’s regulatory ... 4.1 for further information on how this applies to covered bonds Summary of the review 1.15 The aim of this review is to ensure the Regulations continue to support the UK covered bond market The...

Ngày tải lên: 29/03/2014, 06:21

... sources of information Penman also provides structure for some of these external sources of information, including a conceptual hierarchy of relations and entities, called the upper model The upper ... translation Because the prepositional phrase is a modifier of the main process (indicated by the role feature and the fact that the main process and the modifier are siblings in the IS representation) ... should be of interest also for the design of a textbased MT-analysis In summary, then, we have introduced the projects involved, and the structure of the German-Engllsh transfer mechanism, offering...

Ngày tải lên: 09/03/2014, 01:20

... that the overall number of open trials is encouragingly higher However, while the number of cellular therapy trials remained the same, the clear trend was towards an increase in the number of vaccine ... residual disease at the start of vaccine therapy, and concurrent administration of chemotherapeutics [23,24,46-51] For valid conclusions to be reached timely about the value of these approaches ... the patient is categorized as a form of passive immunotherapy The effector cells are administered either systemically or intracranially If placed intratumorally, the effector cells may be either...

Ngày tải lên: 18/06/2014, 16:20

... deformation affecting the stability of the beech plants was found (Fig 3) To verify the further development, the analysis of the root samples will be repeated in the next years CONCLUSIONS The ... of containers were recommended in the Czech Republic (Jurásek et al 2006) The paper presents the results of the morphological parameters of the European beech four years after reforestation of ... between the treatments were found out 454 in the damage or withering of terminal shoots of the planting material (Table 3) In the first year after reforestation, the lowest occurrence of such...

Ngày tải lên: 07/08/2014, 04:20

... improve the performance of a clinical system to be most effective, they must take into account not only the nature of the system, but also the nature of the disease The purpose of this paper is twofold ... learn; the interconnections between individuals; the ability of participants to selforganize; and the tendency of participants to co-evolve Each intervention was given a point for each of the characteristics ... adding a new contact point) Additional File contains detail of each reported intervention and its CAS characteristic rating The raters were blinded to the outcomes of the studies The kappa for these...

Ngày tải lên: 10/08/2014, 10:23

... accord with the beliefs of the majority of transplant professionals, who favour the wishes of the individual over the family in determining donor status” [15], and with the lamentations of a recent ... fragmentation of the body and the role of the medical profession Survey responses are context dependent, and support of organ donation becomes less as the context comes closer to the reality of the organ ... legitimacy of the family decision The discussion might therefore begin (after evident understanding of the fact and meaning of brain death from the family) with a statement such as “There is one other...

Ngày tải lên: 12/08/2014, 20:20

... further viral replication is possible The nature of the retroviral replication process, where the U3 region of both the 5' and 3' LTRs of the provirus are effectively copied from the 3' LTR of the ... which the U3 region of the 3' LTR acts as the template for the U3 region in both LTRs of the provirus As the transcriptional enhancer elements in the 3' LTR are redundant in the context of a retroviral ... transcription of the genome; the primer binding site (PBS) for first strand DNA synthesis during reverse transcription; the psi (ψ) sequence which directs packaging of the genomic RNA into the virion; the...

Ngày tải lên: 14/08/2014, 19:22

... compliance of safety policy of sponsors At the same time, the unit can support other ones when needed The head of the unit is responsible for employees The Project Management Unit is responsible for ... in their application forms including resume, copies of their certificates and a picture of themselves directly to the company or via email The company will select from the application forms the ... organizations, the bargaining of trade unions The internal influences include the size and age of the organization, the labor budget, the job itself, and the employees’ knowledge, skills and abilities Performance...

Ngày tải lên: 20/10/2014, 15:22

... a complete set of results for this time period and therefore precluded the addition of further countries to this study Along with data for the above dependent variable, a number of explanatory ... important factor for this particular dataset, given the changes to trade openness and the impact of the 1997 financial crisis has had on the ASEAN countries Therefore, the two sets of empirical results ... environments within some of the ASEAN nations can expose them to further external shocks that may divert FDI away from these countries Given the reliance of some of these ASEAN countries on FDI,...

Ngày tải lên: 27/06/2015, 22:01

... that either, or both, of the following are true: (1) the assumptions/calculations leading to the creation of the synthetic 13CO observations are faulty; or (2) there is missing physics in the simulation ... Supplementary Information) with a plot showing the fraction of ‘self-gravitating’ (aobs , 2) material as a function of spatial scale for both our L1448 data and for a synthetic data cube4 The simulation ... included in the simulation The accuracy with which dendrograms can offer estimates of aobs is at or below the 25% level (Supplementary Information) The uncertainty results primarily from the need...

Ngày tải lên: 16/06/2016, 01:09

... majority of respondents were supportive of the new warning format • The new warning format clearly undermined brand value (it was the first aspect of the pack mentioned), The new warning format ... objectives of the research Review of the scientific knowledge on health labelling An evaluation of existing warnings on tobacco packages Review of the scientific evidence on the health effects of tobacco ... • 27% agreed with the statement that after reading the warning I am better informed of the health risks 8% of smokers said they now smoke less since the introduction of the new large text warnings,...

Ngày tải lên: 30/10/2016, 07:11

... column to keep the moisture content inside the column uniform while water was sprinkled over the top of the medium until the outflow from the bottom of the column equaled the volume of the water input ... HWCs while there is a slight change of the peak concentration in Andisol (Fig (b)) except for the more pronounced tailing of the BTCs with the increase of HWCs The peak concentrations for Andisol ... differences in the values of the distribution coefficient of two soils Given the fact that the distribution coefficient depends on the specific surface of the medium, Andisols provide the diversity of transport...

Ngày tải lên: 05/09/2013, 10:15

... Efficiency for Total Phosphorus (TP) Removal Fig illustrates the efficiency of the reactors for the removal of TP The highest efficiency for the removal of TP was obtained upon using reactor II, and the ... for COD Removal Fig illustrates the efficiency of the rectors for the removal of COD 90 ammonium mg/L ammonium /mg/L 80 I II III IV 70 60 50 40 30 20 10 0 10 11 12 time/d Fig.3 - Changes in the ... which form countless microcells, then the iron could be reduced The reaction can reduce the toxicity of pollutants, promote growth of microorganism in reactors especially biological degradation for...

Ngày tải lên: 05/09/2013, 10:17

... to the experiment, a stable water level in the reservoir was kept by the overhead tank Once the bottom of the capillary tube contacted with water in the reservoir, the dynamic movement of the ... later stages Therefore, for the long-term CR process, the Washburn equation tended to be an increasing prediction error due to the failure of the assumptions in Equation (2) In spite of this, Equation ... when the initial filling height of sand samples was lower than 20 cm, the inhibition effect of the gas among the pores on the capillary pressure during the CR process tended to be increasing, thereby...

Ngày tải lên: 05/09/2013, 17:03

... difficulties they met are the lack of basic knowledge and new terms Moreover, the main reason they got bad marks are that most of them did not learn EEE until the test Based on the results of this ... Faculty of Foreign Language Ha Noi University of Technology The Situation of Learning English for Electrical Engineering of D06k52 Students in Faculty of Foreign Language, Ha Noi University of Technology ... exception The objective of this report was to investigate the advantages and disadvantages of learning EEE as well as the main reason why they did not get good mark in the final test Techniques of gathering...

Ngày tải lên: 13/12/2013, 12:15

... rate The expression for PPP can then be written (in log-form) as vt = pt − pt* , (1) where pt is the log of the domestic price, pt* is the log of the foreign price, and vt is the log of the nominal ... 4.86 The evidence using the MAE metric (se Table 3) strengthens the results reported above The structural EqCM performs the best of all the models at all horizons (with the exception of the horizon ... is the forecast of (the log of) the actual exchange rate (and not its change) that are compared Following Meese and Rogoff (1983), we perform an out -of- sample forecasting exercise comparing the...

Ngày tải lên: 15/02/2014, 05:20

... THE CONCEPT OF THE VALUE OF MONEY Subjective and Objective Factors in the Theory of the Value of Money The Objective Exchange-Value of Money The Problems Involved in the Theory of the Value of ... to the more abstract parts of the theory of the value of money Professor von Mises shares with Marshall and one or two others the merit of having assimilated the treatment of this theory to the ... to spread beyond the old capitalistic countries of Western Europe, and made the wealth of these countries available for the development of the rest of the world The savings of the few advanced...

Ngày tải lên: 16/02/2014, 03:20

... of the prosodic intent of the speaker The starting point of intonation research is the time series of F0 But the interpretation of the F0 information diverges widely among intonation models The ... considerations They are in part determined from the mechanical functioning of the synthesizer when the latter is of articulatory nature, or from the duration of the prerecorded segments in the case of concatenate ... because they carry information that modifies and can even reverse the meaning of the lexical channel However, in the domain of speech processing, we concentrate on the aspect of speech of prosody...

Ngày tải lên: 19/02/2014, 08:58

... degrading entities [18] For example, the major role of the MMP family is the control of cellular responses critical to homeostatic regulation of the extracellular environment and the immune response ... level match-sets are the reference gels of the respective quadrants from the 2D gel sections of each condition and the four higher-level match-sets are the reference gels of the two different conditions ... enabled the performance of four independent image analyses in which the gel parts of each corresponding quadrant were used to construct four independent reference gels instead of one The corresponding...

Ngày tải lên: 07/03/2014, 06:20