... The UML and Data Modeling Introduction The power of the Unified Modeling Language is not limited to object oriented software development More and more, the UML is being applied to other ... Figure The UML and Data Modeling The diagram representation uses the Index stereotype in front of the operation (Figure 10) Figure 10 The index constraint specifies the columns included and optionally ... It is the biggest element a data model supports The relational database is the standard database supported by the Data Modeling UML profile An object relational database, an extension of the relational...
Ngày tải lên: 10/12/2013, 15:15
... computing the unifier of constrained terms, we would obtain exactly the same terms as in the equational case but annotated with the conjunction of all the constraints attached to the instances of the ... frameworks, such as the feature logic of Smolka 16,15t, by replacing the unification of terms with the unification of the set of equational constraints and by either redefining the constraint language ... grammar and all and only the infon~ation which is needed to satisl'y these constraints will be available at the appropriate moment We justified the use of conjunctive forms as a better option than their...
Ngày tải lên: 18/03/2014, 02:20
báo cáo khoa học: " Improving quality of care through routine, successful implementation of evidence-based practice at the bedside: an organizational case study protocol using the Pettigrew and Whipp model of strategic change" potx
... organization and its related change This reinforces the fluid nature of the dimensions, the signs, and their inter-relationship – the pattern of which may vary from organization to organization and within ... Overall, the process will be both deductive and inductive: i.e., deductive in that key terms and themes relative to the Pettigrew et al model will be used as coding categories; and inductive to the ... However, overall the model focuses researchers and managers on the WHY of strategic change with relevance to context; the WHAT of strategic change in terms of its content; and the HOW of strategic...
Ngày tải lên: 11/08/2014, 05:22
Tài liệu Báo cáo khoa học: Pyrimidine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus – biochemical characterization and homology modeling doc
... of the program, setting the highest level of optimization The quality of the models and their stereochemical properties were analyzed using the programs procheck [65] and prosaii [66], and the ... FUGUE [60] and gave the same results, therefore conrming the correctness of the chosen templates The sequences of target and templates were aligned to each others and to those of the rst 30 nucleoside ... and Ca2+ into the binding site of SsCU-NH was performed using, as a starting reference, the position of the sugar and of the metal in the crystallographic template 1YOE The two ligands were modelled...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana doc
... Prior to the present study, the only model available for the branch-point between the methionine and threonine biosynthesis pathways in the plant was the qualitative model shown in Fig The allosteric ... situation and therefore provides a realistic, detailed description of the branch-point between the methionine and threonine biosynthesis pathways In the following the model is used to investigate the ... computer model of the steady-state in the branch-point The mathematical procedure published previously for the study of the isocitrate branch-point in E coli [2] was adapted to model the Phser...
Ngày tải lên: 20/02/2014, 02:21
Tài liệu Báo cáo khoa học: "The impact of language models and loss functions on repair disfluency detection" pptx
... on a model using the first 25 best analyses We therefore use the top 25 analyses from the noisy channel model in the remainder of this paper and use a reranker to choose the most suitable candidate ... we use the 19 other folds to construct a language model and then score the utterance in this fold with that language model The largest widely-available corpus for language modelling is the Web ... is the log of the “figure of merit” used to guide search in the noisy channel model when it is producing the 25-best list for the reranker The log figure of merit is the sum of the log language model...
Ngày tải lên: 20/02/2014, 04:20
Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... the manganese ions This, together with the fact that the positions of other Fig Scheme of the binuclear manganese cluster and the localization of the side-chains of Asp153 and Asn153 in the modelled ... the modeling of the active site The modelled structure was very similar to the template, with respect to the number and arrangement of structural elements (a-helix and b-sheets), and one of the ... pasted into the structural alignment The alignment was then corrected by hand Since the sequences of the two arginases and agmatinase greately differ in the N terminal region, the agmatinase and rat...
Ngày tải lên: 21/02/2014, 01:21
The Breast Cancer Epidemic: Modeling and Forecasts Based on Abortion and Other Risk Factors potx
... age range 45–49, and the latest abortion and fertility rates Fall 2007 75 entered, the 2006 TAR for Northern Ireland is 0.16, the latest TFR is 1.87, and the forecast increase in the rate of cancer ... 12 The trends in abortion and fertility in Finland are shown in Figures and By using data for recent years it was possible to fit the model The latest available TAR for Finland is 0.34 and the ... Scottish birth rate Northern Ireland 350 300 Rate per 100,000 women 250 200 150 100 50 England and Wales Sw eden Scotland Czech Republic Northern Ireland Finland Republic of Ireland Denmark 1943 1948...
Ngày tải lên: 06/03/2014, 02:21
SAVINGS BANKS AND THE DOUBLE BOTTOM-LINE: A profitable and accessible model of finance doc
... useable The focus of the Kumar and Ellis work is demand side surveys – asking the potential customer at different socio-economic levels – whether they feel they have access and what products they ... Savings banks and the dimensions of access C Savings banks and the provision of access D Savings banks and the double bottom-line 11 Summary of Key Findings 17 Savings Banks and the Dimensions ... for the Future of Microfinance [CGAP 2004] The paper studied a set of institutions that have two bottom-lines – the traditionally known one of the profit and loss account and the equally longstanding...
Ngày tải lên: 06/03/2014, 10:20
An Analyst''''s View Of The Uses And Abuses Of Modeling For Decisionmaking potx
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Functional fine-mapping and molecular modeling of a conserved loop epitope of the measles virus hemagglutinin protein pdf
... with the intact protein (Fig 8B,F) For the binding of the sera to the HNE peptide, the importance of the Cys residues was relatively low, in comparison to the binding with the mAbs BH216, BH21 and ... Similarly, the e-amino group of K387 could form a salt bridge with the close carboxyl group of E395 and further stabilize the peptide structure within the complex with the antibody In the virus, the ... cyclized with a disulfide bond between C386 and C394 and the molecule was protonated at pH 7.4 The model was then energy-minimized using the DISCOVER module of the INSIGHT II package Energy minimization...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: "Combining a Statistical Language Model with Logistic Regression to Predict the Lexical and Syntactic Difficulty of Texts for FFL" potx
... Gerhand and Barry, 1998; Brysbaert et al., 2000) suggests that there is a strong relationship between the frequency of words and the speed with which they are recognised We therefore opted to model ... we can reduce this error, the lemma model may prove to be the best predictor of the three The regression models By the end of the parameterisation stage, each text of the corpus has been reduced ... Because of this, they recommend using the PO model (4) In Equation 4, x is the vector containing the independent variables, αj is the intercept parameter for the jth level and β is the vector of...
Ngày tải lên: 08/03/2014, 21:20
Interest Rates and The Credit Crunch: New Formulas and Market Models potx
... similar to those in the classic LMM The main difference is given by the drift rates that depend on the relevant forward rates for the discount curve, rather then the other FRA rates in the considered ... with another Section extends the market Black formulas for caplets and swaptions to the double-curve case Section introduces the extended lognormal LIBOR market model and derives the FRA and forward ... measures Hints on the derivation of pricing formulas for caps and swaptions are then provided in the specific case of the Wu and Zhang (2006) model Section concludes the article These forward rate...
Ngày tải lên: 15/03/2014, 07:20
The Food Marketing Defense Model: Integrating Psychological Research to Protect Youth and Inform Public Policy doc
... few brands and described their connection to the brands in more concrete terms (e.g., they wear that brand of clothes) Middle and high school students, however, included significantly more brands, ... about the brand mediated the path between ad liking and positive brand attitudes That is, for older children, simply liking the ad led to greater agreement about positive brand attributes, and these ... understand the social world they live in For older children and adolescents especially, media play an informational role as they focus more on the world beyond their families and actively develop their...
Ngày tải lên: 16/03/2014, 01:20
Báo cáo khoa học: The lactate dehydrogenases encoded by the ldh and ldhB genes in Lactococcus lactis exhibit distinct regulation and catalytic properties ) comparative modeling to probe the molecular basis pdf
... [29] Therefore, we measured the activities of PFK and PK in strain FI9078, and found that they were reduced to 48% and 66% of the MG1363 levels Although the activity of these enzymes, i.e 0.48 and ... NADH and mM Fru(1,6)P2 at 30 °C Each value is the average of at least two measurements, and the SD is less than 7% The pH profiles for the activities of LDHB and LDH were compared (Fig 3) The activity ... relative to the already existing ) 10 region, thereby leading to activation of the otherwise silent ldhB gene Analysis of structural models of LDHB and LDH The main folds of LDH and LDHB are...
Ngày tải lên: 16/03/2014, 05:20
Báo cáo khoa học: Effects of the G376E and G157D mutations on the stability of yeast enolase – a model for human muscle enolase deficiency pdf
... view of the structural similarities between yeast and mammalian enolases and the high degree of sequence conservation, we believe that the effects of these mutations on the structure and function ... with the aim of determining whether any of the observed effects were a result of changes in the size and charge of the amino acid at these positions Results Preliminary characterization The G157D ... following the procedure of Shen and Westhead [28] with minor modifications [29]; or (b) PGA was synthesized enzymatically from ATP and glyceric acid [30] PhAH was synthesized according to Anderson and...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Complexes of Thermoactinomyces vulgaris R-47 a-amylase 1 and pullulan model oligossacharides provide new insight into the mechanism for recognizing substrates with a-(1,6) glycosidic linkages docx
... subsites )1 and )2, the substrate conformations and interactions with the enzyme are very similar between D356N ⁄ P2 and D356N ⁄ E396Q ⁄ G6 In both structures, the O2 and O3 atoms of Glc–2 and Glc–1 ... P5) Domains N, A, B, and C are drawn in blue, green, yellow, and pink, respectively The binding substrates and Ca2+ are shown by a wire-style model and as orange spheres The catalytic site, site-N, ... P2 In D356N ⁄ P2, the five glucose units binding to the catalytic site are defined as Glc–5 to Glc–1 from the nonreducing to reducing end The number indicates the subsite, and the site of hydrolysis...
Ngày tải lên: 16/03/2014, 14:20
Báo cáo khoa học: Kinetic studies and molecular modelling attribute a crucial role in the specificity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263 pdf
... close to the position found in the complex with PG [19] The bond lengths and valence angles of the nitroaniline moiety were taken from the X-ray data for the system cyclophilin A and the tripeptide ... The distances between the polar CO2– and O(NO) and positively charged guanidinium fragments of ArgA145 and ArgB263 ˚ Table Distances (A) between polar substrates groups (CO2– and A NO2) and the ... position within the catalytic cavity of PA encounters multiple energy minima Therefore, the way the best of these, i.e the global minimum, was chosen ÔautomaticallyÕ was crucial We used the eigenvector-following...
Ngày tải lên: 16/03/2014, 16:20
Báo cáo " Thailand’s inadequate response to the 2008 Economic Crisis: Implications for Vietnam and other countries entering the East Asian economic model " pptx
... to understand how the economy needs to change in response to current and probably future changes in the global economy It then goes on to describe and analyse the stimulus package and other measures ... required The global economic crisis initiated by the banking crisis of 2008 has revealed the stark nature of the need for radical change in the Thai economy The very model of development on which the ... represent a genuine threat to the status quo The EAEM relates to the economic basis of development of the country; the EADM includes the configuration of the political and cultural aspects that are...
Ngày tải lên: 22/03/2014, 13:20
Báo cáo khoa học: Something from nothing ) bridging the gap between constraint-based and kinetic modelling pot
... in the absence of an accurate kinetic model and detailed kinetic rate equations for each reaction The predictions of the proposed model agree well with the Teusink et al model solutions and, therefore, ... from its reference value The table compares the percentage error between the real model steady states and those predicted by both the correctly parameterized linlog model and its fully estimated ... only the stoichiometry of the network and cellular composition Like mechanistic approaches, our estimated model provides at least an intimation of the kinetic nature and behaviour of the system The...
Ngày tải lên: 23/03/2014, 07:20