the origin of earth and its moon

Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx

Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx

... solution of ThT and the fluorescence intensity of the solution was measured at 482 nm Figure 4A shows the kinetics of aggregation of a-synuclein in the presence of 100 lm MPTP and the effect of 50 ... correspond to the concentration of MPTP originally present in the reaction mixtures (100 and 200 lm, respectively), but were 80% of the original concentrations present in the original samples The components ... a-synuclein was because of MPTP alone and not because of its conversion to MPP+, RP-HPLC of the samples was carried out The incubated samples (a-synuclein alone and in the presence of 100 and 200 lm MPTP)...

Ngày tải lên: 14/02/2014, 19:20

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Tài liệu The Transformation of Banking and Its Impact on Consumers and Small Businesses docx

Tài liệu The Transformation of Banking and Its Impact on Consumers and Small Businesses docx

... The biggest change has been in the importance of so-called megabanks, those that hold more than $100 billion of assets At the end of 1999, there were eight of these giant companies Together they ... broaden the array of products they offer online, making available services such as insurance and brokerage that they either produce themselves or market on behalf of other companies As serious as these ... begun to offer consumers an even more convenient service called bill presentment In this case, the bank collects the bills itself and transmits them to the consumer over the Internet, where the customer...

Ngày tải lên: 16/02/2014, 11:20

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the welding of aluminium and its alloys

the welding of aluminium and its alloys

... consisting of a mixture of the filler metal, if added, and the parent metal(s) The properties of this weld depend upon the composition, the quality and the grain size of the deposit These in their ... on the parent and filler metal compositions, the amount of dilution, the quality of the welding process and the welder and, lastly, the rate of solidification With the exception of a couple of ... either cold working or precipitation hardening One aspect of this is the width of the HAZ, a function of the high thermal conductivity of aluminium and the consequent size of the area where there...

Ngày tải lên: 12/03/2014, 17:32

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báo cáo hóa học:" Unsaturated phosphatidylcholines lining on the surface of cartilage and its possible physiological roles" potx

báo cáo hóa học:" Unsaturated phosphatidylcholines lining on the surface of cartilage and its possible physiological roles" potx

... analysis The total amount of PC was then worked out by adding the amounts of individual PC species together In our study the total amount of PC species was < 20 µg The relative percentages of each of ... ~60 % of all PC species in the lung regions of the body The present results offer further support to the Page of (page number not for citation purposes) Journal of Orthopaedic Surgery and Research ... experiment, the collection, analysis and interpretation of data, the drafting the manuscript and acquisition of funding RWC contributes to the analysis and interpretation of data, drafting the manuscript...

Ngày tải lên: 20/06/2014, 00:20

6 432 0
Insights into the mechanism of safingol and its potential to synergize with anti cancer drugs

Insights into the mechanism of safingol and its potential to synergize with anti cancer drugs

... on toxicity rather than efficacy (7-9) In addition, the approach of MTD ignores the fact that the degree of synergy depends on the concentration and ratio of the combined drugs (9) Therefore, better ... activation of PARP-1 depletes NAD+ pool and ATP Therefore, in the event of extensive DNA damage, massive synthesis of poly(ADP-ribose) drives the cell to death by necrosis On the other hand, when ... (D)1 and (D)2 are the concentrations of drug and drug 2, respectively, that inhibit x% in the actual experiment when they are used in combination (Dx)1 and (Dx)2 are the concentrations of drug and...

Ngày tải lên: 11/09/2015, 10:02

166 459 0
Characterisation of the role of bifocal and its interacting partners in drosophila development

Characterisation of the role of bifocal and its interacting partners in drosophila development

... Similarly RNA like bcd, osk and grk RNA enter the anterior of the oocyte and some of them move towards the posterior of the oocyte or towards the dorsal region of the oocyte These molecules are essential ... rise to the normal polarity of the oocyte and later on the anterior/posterior and dorsal/ventral patterning of the embryo Many of the RNA and proteins required for the normal polarity of the oocyte ... (Bif), its interacting partners and their role in the developing cytoskeleton The work in this thesis focuses on the developing fly eye, the targeting of axons from the eye to the brain and the...

Ngày tải lên: 12/09/2015, 09:42

187 385 0
Characterization of the interaction of EEN and its domains with ca2+ and proline rich domain

Characterization of the interaction of EEN and its domains with ca2+ and proline rich domain

... the dimer by the FPLC because of the large molecular weight (Figure 4.1.3) In further, these polymers may accelerate the process of the EEN aggregation Therefore preventing the formation of the ... acids sequence of ΔBAR domain of EEN Green letters stands for the SH3 domain; Black letters stands for the random coil domain The ΔBar domain which consists of the SH3 domain and the random coil ... studies of the structures and functions of the EEN and its three domains Native PAGE, Circular Dichroism and NMR were used to exploit the interaction of Ca2+ with EEN and its domains 2-D NMR and ITC...

Ngày tải lên: 03/10/2015, 20:32

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DSpace at VNU: Vietnamese Model of Journalism in the Age of Integration and its Effects to the Civil Society and Democracy in Vietnam

DSpace at VNU: Vietnamese Model of Journalism in the Age of Integration and its Effects to the Civil Society and Democracy in Vietnam

... Improving the quality of journalism and strengthening the intellectual standards of the population, Paper presented at The National Journalistic and Publishing Conference, January 1992 Hanoi: The Ideology ... period of industrialisation and modernisation In: Continuing to renovate and strengthen media control and management Hanoi: The Commitee of Central Ideology and Cuture and Ministry of Culture and ... Đ.T.T. Hương / VNU Journal of Sciences, Social Sciences and Humanities 28, No.5E (2012) 57‐64 Central Ideology and Cuture and Ministry of Culture and Information, Enhancing the quality and effects of journalism and...

Ngày tải lên: 14/12/2017, 14:19

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DSpace at VNU: The Function of Saffron and its Constituent in Gastroenterological Tissues

DSpace at VNU: The Function of Saffron and its Constituent in Gastroenterological Tissues

... confirm the incorporation of crocin into cells first and the anticolorectal cancer activities of saffron and crocin in vitro and in vivo in this chapter The Function of Saffron and its Constituent ... IV, On the effect of the active principle and extract of Fructus gardeniae on the bile secretion of rabbits, blood bilirubin and peripheral lymph bilirubin of common bile-duct ligated rabbits Jpn ... expressions of NF-B and Nrf2 in the colonic mucosa were very weak The colonic mucosa of mice treated with 200 ppm of crocin alone showed almost normal histology On the other hand the DSS treatment...

Ngày tải lên: 18/12/2017, 01:18

8 154 0
Evolution of the Earth    and its Atmosphere   and its Atmosphere

Evolution of the Earth and its Atmosphere and its Atmosphere

... much warmer, thereby preventing freezing and accelerating surface “weathering” Except for Oxygen, almost all of the Earth s atmosphere today Evolution of the Earth Process and Equation” its Atmosphere ... led to the appearance☻ of primitive one-celled aquatic organisms which could survive in the oceans Life on Earth had begun, despite its inhospitable atmosphere! Evolution of the Earth and its Atmosphere ... 200 years ago, the industrial age, with its demand for fossil fuels, was getting underway ♦ The impact of people on the atmosphere was about to become noticeable! The Earth and its Atmosphere...

Ngày tải lên: 04/04/2013, 10:51

18 517 0
Báo cáo sinh học: " Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus" pptx

Báo cáo sinh học: " Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus" pptx

... analysis and interpretation of the data, participated in the idea and design of the models proposed and in the drafting and revision of the manuscript IDM collected the data resulting from the transfections ... Replication of Parvovirus LuIII Proposed Model for the Replication of Parvovirus LuIII A model for the replication of the (+) and the (-) strand of LuIII is shown The NS1 nick site and its complementary ... drafted and revised critically the manuscript, had the intellectual idea of the study and its design, contributed significantly in the analysis and interpretation of the data, proposed the replication...

Ngày tải lên: 19/06/2014, 08:20

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báo cáo hóa học:" Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus" ppt

báo cáo hóa học:" Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus" ppt

... analysis and interpretation of the data, participated in the idea and design of the models proposed and in the drafting and revision of the manuscript IDM collected the data resulting from the transfections ... Replication of Parvovirus LuIII Proposed Model for the Replication of Parvovirus LuIII A model for the replication of the (+) and the (-) strand of LuIII is shown The NS1 nick site and its complementary ... drafted and revised critically the manuscript, had the intellectual idea of the study and its design, contributed significantly in the analysis and interpretation of the data, proposed the replication...

Ngày tải lên: 20/06/2014, 04:20

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Information, Entropy, and the Origin of Life

Information, Entropy, and the Origin of Life

... account for the diversity of life in the biosphere, it is generally recognized that the origin of life is one of the great unsolved mysteries in science (Radetsky1992; Wade 2000) At the heart of this ... are able to sustain themselves against the downward pull of the Second Law of Thermodynamics and how thermodynamics affects the origin of information-rich, living systems Finally, we will explore ... of life appears to be its capacity, through the use of information, to survive and exist in a nonequilibrium state, resisting the pull toward equilibrium that is described by the Second Law of...

Ngày tải lên: 01/11/2013, 07:20

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Tài liệu Báo cáo khoa học: Characterization of human deoxyribonuclease I gene (DNASE1) promoters reveals the utilization of two transcription-starting exons and the involvement of Sp1 in its transcriptional regulation ppt

Tài liệu Báo cáo khoa học: Characterization of human deoxyribonuclease I gene (DNASE1) promoters reveals the utilization of two transcription-starting exons and the involvement of Sp1 in its transcriptional regulation ppt

... and quantitative real-time RT-PCR, the locations of the primers DN)105 and DN)9 used in ChIP assays, the locations of the primers DN+232 and DN+254 utilized in 5¢-RACE, and the locations of the ... in fragments F and I The number at the right of each RT-PCR product represents the length of the product The scheme also shows the location of the reverse primer DN+89 used in another starting ... numbers over the diagrams indicate the position of the corresponding nucleotides relative to the translation start site, and the numbers in parentheses below the diagram show the position of the corresponding...

Ngày tải lên: 19/02/2014, 06:20

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Báo cáo khoa học: N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding pptx

Báo cáo khoa học: N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding pptx

... end of an a-helical region of the HFE a1 domain (V100 and W103A) as being of particular importance for TfR1 interactions [16,17,20] The effect of HFE binding to TfR1 is to lower the affinity of the ... 3222 in the presence or absence of tunicamycin Drug treatments resulted in the accumulation of forms of the mutant proteins that were of lower apparent molecular mass and of similar size to the unglycosylated ... mutant forms of HFE and incubated the cells in the presence and absence of tunicamycin Drug treatment resulted in the accumulation of an unglycosylated lower molecular mass form of the wild-type...

Ngày tải lên: 06/03/2014, 22:21

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Báo cáo khoa học: Sequences and structural organization of phospholipase A2 genes from Vipera aspis aspis, V. aspis zinnikeri and Vipera berus berus venom Identification of the origin of a new viper population based on ammodytin I1 heterogeneity docx

Báo cáo khoa học: Sequences and structural organization of phospholipase A2 genes from Vipera aspis aspis, V. aspis zinnikeri and Vipera berus berus venom Identification of the origin of a new viper population based on ammodytin I1 heterogeneity docx

... 3, and the 5¢ part of exon encode the mature protein; exon encodes the 5¢-UTR, and exon and part of exon encode the signal peptide The 110 nucleotides at the 3¢ end of exon encode the 3¢-UTR The ... Ib in the genome of this snake These findings provide clues to the evolutionary position of the neurotoxic V a aspis population with respect to the other snakes studied The genome of one of these ... indeed the case, then substitutions occurring in these areas may affect the neurotoxicity or anticoagulant effect of the PLA2 The substitutions in the A and B chains of vaspin, in the inhibitor and...

Ngày tải lên: 17/03/2014, 03:20

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A Philosophical Inquiry Into The Origin Of Our Ideas Of The Sublime And Beautiful

A Philosophical Inquiry Into The Origin Of Our Ideas Of The Sublime And Beautiful

... pain and danger, they not dwell on the pleasure of health and the comfort of security, and then lament the loss of these satisfactions: the whole turns upon the actual pains and horrors which they ... scorneth the multitude of the city, neither regardeth he the voice of the driver The range of the mountains is his pasture The magnificent description of the unicorn and of leviathan, in the same ... Imitation, and Ambition 13 Sympathy 14 The Effects of Sympathy in the Distresses of Others 15 Of the Effects of Tragedy 16 Imitation 17 Ambition 18 The Recapitulation 19 The Conclusion Part II Of the...

Ngày tải lên: 18/03/2014, 11:11

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Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx

Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx

... HD These processes may not be independent of each other Detailed descriptions of these processes are beyond the scope of this review In the present review, we specifically focus on the role of ... (45 kDa) and the activated caspase-1 (20 kDa) are shown by the arrows on the left The bar diagram (right panel) shows the average (n = 3) of integrated optical density (IOD) of the bands obtained ... that of the mutated Htt [17] In HD, one of the alleles of Htt is mutated and thus likely to release free HIP-1 Free HIP-1 then interacts with HIPPI through its C-terminal pDED domain and recruits...

Ngày tải lên: 23/03/2014, 07:20

9 492 0
Báo cáo khoa học: Modeled ligand-protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase pptx

Báo cáo khoa học: Modeled ligand-protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase pptx

... demonstrated that the two hydroxyl groups of the catechol moiety bind to the catalytic iron [16–18] Despite the similarities between TH and PAH regarding the structure of the active site and the catalytic ... atom may be placed between the ring of the amino acid substrates and the active site iron, the maximal distance dTyr-Fe or dPhe-Fe between the center of the ring and ˚ the iron atom was defined ... monodentate and other binding modes to be included in further analysis Results Pterin binding to the catalytic domains of PAH and TH Docking of the native cosubstrate BH4 into the crystal structure of the...

Ngày tải lên: 31/03/2014, 07:20

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Báo cáo Y học: Ascidian arrestin (Ci-arr), the origin of the visual and nonvisual arrestins of vertebrate pdf

Báo cáo Y học: Ascidian arrestin (Ci-arr), the origin of the visual and nonvisual arrestins of vertebrate pdf

... on the nucleotide sequence of the PCR products, specific primers were synthesized and used for 5¢- and 3¢-RACE Based on the sequence of 5¢- and 3¢flanking region of ORF of Ci-arr (Ar-full-N (5¢-CTGT ... 2002 Origin of vertebrate visual and nonvisual arrestins (Eur J Biochem 269) 5115 Comparison of two types of cDNA and genomic DNA revealed that splicing of intron 11 resulted in the shift of the ... sense organ and the posterior pigment is ocellus (OC) The expression of Ci-arr is restricted to the photoreceptors in the right side of the OC Fig Phylogenetic tree of arrestin family The molecular...

Ngày tải lên: 31/03/2014, 08:20

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