the optimal form of organization

... a is the Q-H curve of which the pump runs with the rated speed n0, b is the Q-H curve of which the pump runs at the speed of n1, n1=0.75n0, HS is the pump head which can be determined by the outlet ... K should be added to the lower limit of the speed ratio according to the pump characteristic, then d in Figure is the Q-H curve of the pump at present Therefore, the range of each variable speed ... to the pressure of the control node after the hydraulic calculation, H c, j , H c, j max refer to the minimum and maximum allowable pressure of the control node, HJk,j is the pressure of the...

Ngày tải lên: 05/09/2013, 09:38

Ngày tải lên: 26/12/2013, 01:18

... a snake.were / wouldn't want 14 My brother managed to kill the snake just at the time when I (be) almost exhausted If he (be) a little late, I (kill) by the snake.was / had been / would have ... a snake 14 My brother managed to kill the snake just at the time when I (be) had been almost exhausted If he (be) had been a little late, I (kill) would have been killed by the snake 15 Had I ... in a snake 14 My brother managed to kill the snake just at the time when I were almost exhausted If he had beena little late, I would have killed by the snake 15 Had I know you were ill, I (visit)would...

Ngày tải lên: 23/01/2014, 07:20

... Furthermore, the pro-peptide of GDF-8 impairs interaction of the mature part with its receptors [16] In the case of BMP-9, the pro-peptide appears not to alter significantly the activity of the ... interested in the role of the 263 amino acid pro-peptide of BMP-2, because evidence accumulated over recent years has shown that the pro-forms of growth factors can modulate the activities of the mature ... patients [39], and a role of the receptor in the development of the arthritis has been discussed [26] The data presented here provide clear evidence that the pro -form of BMP-2 can interact with...

Ngày tải lên: 18/02/2014, 06:20

... In the first step of the enzymatic reaction, a nucleophilic attack is performed on the anomeric carbon of the sugar substrate by the carboxylate of the Asp54 acting as the primary nucleophile, forming ... anomeric carbon of fructose The leaving group is carboxylate of Asp54 Dimerization The asymmetric units of the crystals of both the apo and complexed form of the enzyme consist of dimers with ... results of MS of recombinant b-fructofuranosidase are close to the theoretical value of the molecular mass A peak of molecular ion at m ⁄ z = 58 879 Da was observed on the MALDITOF mass spectrum The...

Ngày tải lên: 06/03/2014, 00:21

... coprecipitated only the slowly migrating form of RNA pol II (Fig 1) This suggested that Pol e associates with the RNA pol IIO isoform To characterize further the phosphorylation status of the RNA pol ... isoform IIO that exhibits reduced electrophoretic mobility compared with the IIA isoform Whereas the polyclonal antiRNA pol II antibody precipitated both the fast and slowly migrating forms of ... Following phosphatase treatment, the cellular fraction of RNA pol II that associated with Pol e showed increased mobility, corresponding to that of isoform IIA The isoform IIO was also lost from RNA...

Ngày tải lên: 07/03/2014, 11:20

... regulation of the PKI and PKI isoforms of the inhibitor protein of the cAMP-dependent protein kinase J Biol Chem 272, 20011–20020 Byler, D.M & Susi, H (1986) Examination of the secondary structure of ... for further study The concentration of the proteins was determined by the method of Lowry et al [14] and the purity was examined by SDS/PAGE [15] Assay of human PKIb activity The activity of purified ... Characterization of PKI gamma, a novel isoform of the protein kinase inhibitor of cAMPdependent protein kinase J Biol Chem 272, 18169–18178 Gamm, D.M & Uhler, M.D (1995) Isoform-specific differences in the...

Ngày tải lên: 07/03/2014, 15:20

... that of its unglycosylated form, though the DV and DGP values were almost the same The Pm value of proCPY was higher than that of its unglycosylated form This is due to the higher DV value of the ... that the precursor form was less thermally stable than the mature form, regardless of the carbohydrate moiety After the temperature was lowered from the highest temperature tested to 25 °C, the ... (Fig 1A), indicating that the thermal unfolding process of the precursor form follows a two-state transition The ratio of the unfolding enthalpy (DHcal) to the van’t Hoff enthalpy (DHv) was 1.05...

Ngày tải lên: 07/03/2014, 21:20

... between the two proteins (as indicated by the values of DGwater, Cm and Tg) hence arise from the changes in the surface of the protein because of the interactions of the cofactor with the protein ... are comparable, the Tg values of the proteins vary slightly; there is a difference of almost °C between the Tg values of the proteins, the value being higher for the holo form There have been ... unfolding thermodynamic parameters of the two forms are given in Tables 1–3 In the entire experimental regime, it is seen that the holo form presents better stability than the other form (Fig 4C) The...

Ngày tải lên: 16/03/2014, 10:20

... structure of the soluble form of CLIC4 the backbone and side chain of Asn34 and the side chain of Lys24 This crystal contact stabilizes the structure of the leading side of the foot loop The putative ... the side chain of Asn81 The intervening residues of the C-terminal extension interact with the neighboring monomer via hydrophobic contacts Comparison with the structure of the soluble form of ... reduction in the size of the protein, leaving a kDa fragment [4] This supports the hypothesis that the integral membrane form of the protein has a single transmembrane region near the N-terminus...

Ngày tải lên: 23/03/2014, 15:21

... (Note also the comprehensive denotation of edible) No other theory we know of can account for the validity of these two arguments Both of these theories take it that is wine is true of the (abstract) ... assigning the same logical form to both theories Nonetheless, the meaning postulates of the two theories will differ for these.) In addition to the sorts of examples stated above, both these theories ... true of unions of elements of the semilattice) These predicates are not only true of the conventional kinds but also of conventional servings such as the bottle of wine on the table or the 250ml...

Ngày tải lên: 24/03/2014, 01:21

... stochastic model of the width of the corridor and its impact on overnight rate stability 14 The impact of the corridor width on market turnover 18 The width of the corridor and the length of the central ... σ2 (7) Proof See Appendix Hence, interbank turnover is some function of the size of the initial and the interbank shocks, the volatility of the end of day aggregate shock, the width of the standing ... What, then, should be the optimal width of the standing facilities corridor? The optimal width of the corridor The reaction of central banks to these trade-offs will obviously depend on their...

Ngày tải lên: 29/03/2014, 13:20

... [43] The present study further illustrates the importance of the eightpeptide sequence 57–64 in maintaining the inhibitory effect of the original 20-peptide aIIb 49–68 The N-terminal region of the ... that of the RGDS, used as a positive control (Table 1) We next investigated whether the above inhibitory effects of our peptides are a result of their interaction with the activated form of aIIbb3 ... were performed in the presence of PAC-1, a ligand-mimetic anti-aIIbb3 that contains the RYD sequence (an RGD mimic) in the CDR3 region of the heavy chain PAC-1 binds to the activated form of aIIbb3...

Ngày tải lên: 31/03/2014, 07:20

... °C The cells were then washed and reincubated with new medium for up to h at 37 °C The release of the 125I-label into the efflux medium from the cells was then assessed (Fig 7) The release of ... proportion of the 125I released (Fig 7A) may be derived from the diffusion of low Mr 125I from the cells In contrast, the slower release of 125I-Tf (Fig 7B) was consistent with the efflux of the 4442 ... of conjugates compared to free agents [49,50] It is possible that the use of the conjugate may enable the delivery of the agent to the lysosomal compartment that then results in degradation of...

Ngày tải lên: 31/03/2014, 09:20

... divides the set of samples such that all the points with the same class are on the same sides of the hyperplane Let wo and bo denote the optimum values of the weight vector and bias, respectively The ... define the two borders of margin of separation, are specified on (4) According to (4), the optimal separating hyperplane is the maximal margin hyperplane with the geometric margin 2/ w Hence, the optimal ... hyperplane is the one that satisfies (4) and minimizes the cost function, L Φ(w) = wT w + C ξi i=1 (6) The parameter C controls the tradeoff between the complexity of the machine and the number of nonseparable...

Ngày tải lên: 22/06/2014, 23:20

... one of the best football in the world (play) The town is situated on the river (attract) How can you imagine the of mathematics in our modern life? (important) The book is very to me (use) The of ... How of you to break that cup (care) I will never forget the holiday in Italy (wonder) I regret to you that they are unable to offer you employment (information) You are very from your brother ... is thinking of English (study) Do you like to solve puzzles? (mathematics) The to the problems will be difficult to find (solve) He is the most pupil in our class (intelligence) The company is...

Ngày tải lên: 21/07/2014, 21:20

... to men EQUAL He refused the request for help of his friend GRATE He’s terribly absent – minded He even sometimes _ the number of his children COUNT The weather was so terrible that we ... kind worth thousands of pounds REPLACE Exercise She hates the taste of cigarette She must choose a _ to be her husband SMOKE To our great _, it rained on the day of the picnic APPOINT I ... students for their exams RESPONSIBLE There are so many _ mysterious in this case SOLUTION On such a hot day, the sea was RESIST 10 It’s an antique vase It’s the only one of its kind...

Ngày tải lên: 22/07/2014, 12:21

... to men EQUAL He refused the request for help of his friend GRATE He’s terribly absent – minded He even sometimes _ the number of his children COUNT The weather was so terrible that we ... kind worth thousands of pounds REPLACE Exercise She hates the taste of cigarette She must choose a _ to be her husband SMOKE To our great _, it rained on the day of the picnic APPOINT I ... students for their exams RESPONSIBLE There are so many _ mysterious in this case SOLUTION On such a hot day, the sea was RESIST 10 It’s an antique vase It’s the only one of its kind...

Ngày tải lên: 22/07/2014, 12:21

... It’s the only one of its kind worth thousands of pounds REPLACE Exercise She hates the taste of cigarette She must choose a _ to be her husband SMOKE To our great _, it rained on the day of ... insight into the in his behaviour SINCERE It’s _ of you not to prepare students for their exams RESPONSIBLE There are so many _ mysterious in this case SOLUTION On such a hot day, the sea ... absent – minded He even sometimes _ the number of his children COUNT The weather was so terrible that we had an _ holiday PLEASE 10 In my opinion, weather forecasting is an EXACT Exercise...

Ngày tải lên: 06/08/2014, 12:22