the obvious and the novel

... Travel in Egypt, Arabia Petraea, and the Holy Land, on the other hand, was published Clearly, the Harpers placed great hope in Stephens.12 The ®rm's decision to publish and to promote Stephens's work ... a source, Poe revised and adapted the passage to make it a microcosm of the American journey to the West Coming from the East, the The novel 71 buffalo attempt to cross the river, but, unable ... compares the sound of the maelstro m with that of the buffalo moaning, and the story ends with the setting moon, an analogue for the setting sun The old Norwegian guide who survives his brothers...

Ngày tải lên: 01/11/2013, 09:20

... allusions with her political theme The most obvious of these is the dynamic of the thriller, which leaves Grace’s fate unclear until the The State and the Novel 35 final page The other is an extended allusion ... anglophobe’, The State and the Novel 15 who feels the British, lacking ‘literature, culture, language and manners’, flatter themselves as the liberators of the French (it is the French and the Americans ... of the novel, and the uncertainty about character and motivation that accompanies it But since that sense of limitation and uncertainty stems from the state of the nation the novel discovers, then...

Ngày tải lên: 01/11/2013, 10:20

... further evidence that the functions of Vrp1p in endocytosis, cytokinesis, and growth at elevated temperature, on the one hand, and in cortical actin-patch polarization, on the other hand, are at least ... in G buffer The beads were washed extensively and the bound proteins were eluted The eluted proteins were resolved by SDS ⁄ PAGE and the proteins were transferred to a PVDF membrane and immunoblotted ... coli, the encoded proteins were expressed and affinity purified, and beads bearing the purified proteins were incubated with crude yeast cell lysate The beads were washed extensively and the bound...

Ngày tải lên: 18/02/2014, 16:20

... XL10 and the frame and the identity of the cloned fragment verified by sequencing The construct with the N-terminal portion of PPI1 has been previously described [22] The DNA fragment coding for the ... et al ([1] and references therein) The auto-inhibitory action of the C-terminus is suppressed, besides by pH, by lysophospholipids and by 14-3-3 proteins ([1] and references therein) The latter ... H+-ATPase in the PM and stimulate its activity [22], suggested that the site of interaction with the PM H+-ATPase was localized in the N-terminus of PPI1 To further characterize the biological...

Ngày tải lên: 19/02/2014, 07:20

... removal of the CUB domains and thereby activation of the growth factor domains PDGF-C and -D contain both the CUB and growth factor domains when they are secreted and proteolytic cleavage is therefore ... of the proposed PDGF-C model [57] displaying the twisted b-sheets and the N-terminal a-helix of the PDGF-C monomer (A) and the PDGF-CC dimer (B) The N-terminal (N) and C-terminal (C) ends for the ... the cytoplasm and nucleus, a feature also described for PDGF-B [31,32] The function of these two PDGFs in the nucleus is unclear The region N-terminal of the CUB domain in PDGF-C and PDGF-D The...

Ngày tải lên: 19/02/2014, 07:20

... corresponding to the immunoreactivity of ERK1/2 and phospho ERK1/2 (A,B), and MEK1/2 and phospho MEK1/2 (C,D) The lower part of each panel reports the quantitative analysis of phospho ERK1/2 (A,B), and phospho ... to be elucidated and are the subject for future investigations Nevertheless, the cellular targets and signaling mechanisms uncovered in the present study are associated with the modulation of ... GPCR- and receptor tyrosine kinase (RTK)-mediated signaling and that the activation of ERK by GPCRs closely parallels that employed by RTK [33] On the whole, these observations suggest that the...

Ngày tải lên: 21/02/2014, 01:21

... individual diagnosis and therapy, and an understanding of the structure of these allergens is essential to the improvement of diagnosis and the design of adequate therapeutic treatment We previously ... to the N-terminal portion of the allergen Based on this partial sequence, two specific primers were designed and used together with the anchor primer AP2 to obtain the 5¢ and 3¢ portions of the ... sequence and sequence alignment of Cyn d 24 (A) Nucleotide and deduced amino acid sequences of Cyn d 24 The numbers on the right of the figure indicate the positions of the nucleotide sequence The...

Ngày tải lên: 07/03/2014, 12:20

... unique features such as the organization of disulfide bonds at their N- and C-termini, with the cysteine residues following a class-specific topology, and on the basis of their genomic organization, ... cells [50] The interplay between decorin and the EGFR is further underscored by osteosarcoma cells which escape the decorin-suppressing activity via protracted expression and activation of their endogenous ... tubular epithelial cells [57] In addition, decorin binds to and sequesters the IGF-I (KD  18 nm), the natural ligand of this RTK [55] By binding to the IGF-IR, decorin triggers phosphorylation and...

Ngày tải lên: 15/03/2014, 23:20

... involved in the normal development of heart and other organs in embryonic and fetal stages The third highest signal in the cDNA dot-blot corresponds to fetal heart and the sixth highest to the interventricular ... rather reflects synchrony to other events of the spermatogenesis For instance, the mechanisms unleashing the pass of the haploid germ cells through the tight junctions from the adluminal to the ... been argued that the germ cells themselves may signal the Sertoli cells their entry to meiosis, triggering their transport through the blood–testis barrier [43] On the other hand, apoptotic germ...

Ngày tải lên: 16/03/2014, 23:20

... liked the film better than the novel for several reasons The novel gave good descriptions of the characters but I learned more about them and the story form the film because I was watching and ... of the novel we know what that George has Carlson's gun and then we know what is going to happen At the end of the film, we don't know George has the gun and we can't see that he is holding the ... young and handsome to be the character I had envisioned Overall, the casting and photography was excellent Another reason why I liked the film better was because of its dramatic conclusion At the...

Ngày tải lên: 21/03/2014, 22:48

... differences between themselves in the novel and the film The melodramatic film takes away from the novel' s descriptive plot The first major difference I noticed was in the level of detail The novel seemed ... than the film The film basically focused on the relationships between the characters which left out much of the novel' s detailed plot The major part of the novel' s detail which was left out of the ... was the minor but Cano-4highly significant changes of the plot In the novel, the first three chapters of the book describe the events leading up to the bombing in detail The movie starts with the...

Ngày tải lên: 21/03/2014, 22:53

... repeated by the audience of neophytes and members (their guides), and then the whole process is repeated twice yet again by other Speakers The time taken varies with the Speaker and the degree ... nd the suppression of owers, of religious (and other) images, and of the theater The novel shares in this history In the Sichuan town of Yebin during the Cultural Revolution, Jung Changs mother ... genealogy, and praises they sing the jeeli of Mandingo origin, who play many instruments, are unattached, and make their living by their profession the nyemakala, wandering singers and guitarists...

Ngày tải lên: 11/06/2014, 16:27

... varies between 10 and 60% [13], while their symptoms depend on the type and the amount of the pituitary hormone secretion and/ or the compression effects due to the size of the tumour [26] Pituitary ... operation and contributed to the preparation of the manuscript; ND assisted to the operation and wrote the manuscript; AZ prepared preoperatively and followed-up postoperatively the patient, wrote the ... manuscript and reviewed the literature; SS and KE performed the histopathology; SK performed the genetic test; PK performed the histopathology and immunohistochemistry; GK diagnosed the case, checked the...

Ngày tải lên: 09/08/2014, 01:24

... characterization of the HTLV4(1863LE) structural and enzymatic proteins, and the LTR The genomic structure of HTLV-4(1863LE) was similar to that of other PTLVs and included the structural, enzymatic, and regulatory ... despite the identification of other novel STLVs in this region [9,10,22] Nonetheless, the inability to find "STLV-4" may be due to sampling and screening biases in the selection of NHP species and the ... HTLV-1 and HTLV-3 [27] The absence of PDZ suggests that the HTLV-4 Tax may be more phenotypically similar to the HTLV-2 than the HTLV-1 Tax Furthermore, the high amino acid identity of the Tax4 and...

Ngày tải lên: 13/08/2014, 05:21

... (and) then, (and) afterwards, first…then, and just then, at the same time, and at this time For example: The lights have gone out: now we won‟t be able to any more They spread the cloth on the ... “White Fang and the Indians” in the novel “White Fang” by Jack London) starts with the scene that the cub came upon them suddenly in the native American village The cub‟ is White Fang, and „them‟ ... of the study The study is organized around parts: Part A states the reasons for choosing the topic, the aim, research questions, the scope, data collection, the methods of the study, and the...

Ngày tải lên: 02/03/2015, 14:32

... IN CHAPTER “WHITE FANG AND THE INDIANS” IN THE NOVEL “WHITE FANG” BY JACK LONDON 2.1 Introduction 28 2.2 The context of the chosen text 28 2.3 Contextual configuration of the text 29 2.3.1 Field ... of figures and tables v Table of contents vi PART A: INTRODUCTION Rationale Aim of the study and Research questions Scope of the study Data collection Methods of the study Design of the study ... of context 1.4 Grammatical rank scale 1.5 Clause and clause complex 1.5.1 Clause and its position in functional grammar 1.5.2 Clause simplex and clause complex 1.6 Logico-semantic relations between...

Ngày tải lên: 10/08/2015, 19:51

... between Si and the impurity atoms, which further might be dependent on the specific [Chapter Modeling and Methodology] 25 position of the impurity In the present thesis, the use of DFTB and DFT ... has an indirect band gap, with the valence-band-maximum (VBM) locates at the Γ point and the conduction-band-mimimum (CBM) locates approximately 85% from Γ to X The indirect band gap characteristic ... ABSTRACT THE NOVELTY AND SURFACE-TO-VOLUME-RATIO DEPENDENT ELECTRON BAND STRUCTURE IN SEMICONDUCTOR NANOWIRE By Donglai Yao In the field of nanotechnology, we focus this thesis on the novelty and...

Ngày tải lên: 09/09/2015, 18:55

... Medicine, NUS Their encouragement and guidance and their critique has been of paramount importance in directing the course of the work leading to this dissertation and all the knowledge and skills ... by the ANT in the inner mitochondrial membrane and the VDAC in the outer mitochondrial membrane and cyclophilin D in the matrix (Green and Kroemer, 2004; Zamzami and Kroemer, 2001) And a sudden ... Conventional drugs and the pathways they influence have been the subject of immense interest to biologists, and there has been some headway in understanding the signal transduction pathways these drugs...

Ngày tải lên: 14/09/2015, 14:04

... told?’ said the midwife, meaning the father (3 – 4) 24 After this, the point of view changes to the father of the child The switch from the narrator to other points of view is rather rapid and confusing ... Lambert: The voices spoke again Someone said in Malay: “They will take the right hand track on the other side of the estate.” The estate is free of the Hantu Pendek?” “Yes, they have shifted their ... transcriptions and the use of different levels of Singapore-Malayan English The introduction provides the rationale for the selecting of novels and the theoretical basis for the discussion of the text...

Ngày tải lên: 16/09/2015, 08:30