... site The inhibition of cargo delivery to the lysosomes in either LEX2 or LEX1 cells would again increase the pool of saporin available for passage from the endosomes to the cytosol and would thereby ... to the late endosomes is the major site for dimethylsulfoxide-facilitated entry of saporin into the cytosol The LEX2 inhibition of cargo delivery to the late endosomes would thereby increase the ... (Fig 2) The cells were then incubated for another 16 h in the absence of saporin and dimethylsulfoxide before determining the extent of intoxication As shown in Fig 2A, cells shocked with dimethylsulfoxide...
Ngày tải lên: 07/03/2014, 05:20
... their training, the theories underpinning their profession and the types of interventions they provide [103] Therapists' perceptions of their therapeutic relationships with patients with schizophrenia ... clarity of the research question or hypothesis, the type of methodology used [16] and relevance of the participants to the aims of the review); (4) data analysis (which included clarity of the analysis ... with Recovery Much of the evidence provided overlaps with the concept of "Recovery", which originated from the narratives of people with personal experience of mental health problems [131], and...
Ngày tải lên: 11/08/2014, 17:20
Báo cáo y học: "microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder" ppsx
... Foundation and NIH Public Health Service 5P20-RR020751-01-02 (CDJ), the Foundation of Hope (DOP), and the American Cancer Society (JMT) The contents of this paper are solely the responsibility of the ... (transcription of pri-miRNA) Discovery of parallel mechanisms of regulation of other sets of miRNAs, such as the 15 downregulated miRNAs in schizophrenia, would, therefore, be of considerable interest Further ... target sites in the 3' UTR of a protein coding gene, for example the program miRanda [7] The potential targets of miRNAs often include hundreds of genes because the reverse complement of some 'seeds'...
Ngày tải lên: 14/08/2014, 18:20
báo cáo hóa học: " The Locomotor Capabilities Index; validity and reliability of the Swedish version in adults with lower limb amputation" ppt
... fitted with a prosthesis may differ in how much they use the prosthesis and in the type of activities they can perform with their prosthesis [7] Procedure of translation The procedure of cross-cultural ... basic, and advanced locomotor skills of the lower limb amputee with the prosthesis and assesses level of independence" [13] The LCI has demonstrated good validity and reliability in adults with ... better function with the prosthesis would correlate with better EQ-5D index) The correlation between the LCI scores and the TUG test results and the EQ-5D scores were calculated with the Spearman...
Ngày tải lên: 18/06/2014, 18:20
The role of precautionary labelling for food allergens and the care of children with food allergies
... in the care of the allergic patient 16 General Declaration I, Giovanni Zurzolo, declare that the PhD thesis entitled ‘ The Role of Precautionary Labelling for Food Allergens and the Care of Children ... accomplish the task at hand and have provided me with educational and emotional support I will always be grateful for the time that I have spent here with you and for the fine example of the pursuit of ... research 19 To the participants and their families who took part in the studies: without them none of this would have been possible And finally to the ever expanding HealthNuts and School Nuts...
Ngày tải lên: 04/12/2015, 13:59
Tài liệu The National Survey of Children with Special Health Care Needs Chartbook 2005–2006 docx
... information on the prevalence of CSHCN in the Nation and in each State, the demographic characteristics of these children, the types of health and support services they and their families need, and their ... $250 or more on health care in the previous year for the care of their CSHCN The families of 13 percent of CSHCN spent between $501 and $1,000, and the families of 20 percent of children spent ... relationship with the child’s health care providers and recognizes the importance of the family’s customs and values in the child’s care To measure family-centeredness of care, the survey asked...
Ngày tải lên: 12/02/2014, 11:20
Tài liệu Nursing Care of the Pediatric Neurosurgery Patient pdf
... and successful treatments in the field of pediatric neurosurgery That coincided with the evolution of the expanded roles and responsibilities of nurses As the members of the healthcare team with ... Mod (0–9% of the time) (10–39% of the time) (40–69% of the time) Max (>70% of the time) Eye squeeze None Min Mod (0–9% of the time) (10–39% of the time) (40–69% of the time) Max (>70% of the time) ... shape and size and assessment of the fontanels, there are other aspects unique to the neurological exam of the neonate and/ or infant These are important to understanding the integrity of the nervous...
Ngày tải lên: 16/02/2014, 22:20
Báo cáo khoa học: DNA polymerase e associates with the elongating form of RNA polymerase II and nascent transcripts pot
... (complete), without BrdUTP (no BrdUTP), without dNTP precursors and with aphidicolin (+ aph, no dNTP) or in the presence of a-amanitin (a-amanitin) The photolabelled derivatives of Pols a and e were then ... to the control area of the same nuclei (Fig lower panel) Overall, the staining intensities of RNA pol II and Pol e not correlate, and there is only a very minor effect of local UV damage on the ... we tested the effect of the replicative state of the cell on the interaction between Pol e and RNA pol II A possible confinement of the interaction to late G1 and S phases (the cell cycle stages...
Ngày tải lên: 07/03/2014, 11:20
Báo cáo khoa học: Mitochondrial transcription factor A overexpression and base excision repair deficiency in the inner ear of rats with D-galactose-induced aging pdf
... harboring the common deletion By applying the specific probe, we can even detect the presence of the common deletion in the inner ear in the control group The proportions of the common deletion in the ... at the basal turn of the cochlea Inner hair cells were generally intact Figure shows typical images of hair cells of the organ of Corti from the high-dose d-Gal group They were taken from the ... side of the cochleae was used for mtDNA analysis, and the other was used for RNA extraction (see below) Total DNA was extracted with the standard SDS–proteinase K method The DNA concentration of...
Ngày tải lên: 14/03/2014, 23:20
Báo cáo khoa học: Nitric oxide formation from the reaction of nitrite with carp and rabbit hemoglobin at intermediate oxygen saturations pdf
... Discussion The results of the present study show that the reaction of nitrite with deoxyHb is favored over that with oxyHb at intermediate So2 values and that the formation of NO and HbNO from the reaction ... max (àM) The addition of ATP to stabilize the T state and to impede the T to R transition caused the disappearance of the well-dened peak for the deoxyHb reaction rate and decreased the absolute ... that the production of HbNO depended on So2, the species-specic O2 afnity (carp against rabbit) and the relative stabilization of the T state versus the R state of Hb (presence and absence of ATP)...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Interaction of the C1 complex of Complement with sulfated polysaccharide and DNA probed by single molecule fluorescence microscopy pdf
... C1r and the CLR fragments of C1q were labeled with fluorescent beads The concentration of beads was adjusted according to the type and the concentration of protein in order to maximize the rate of ... Incubation of T4 DNA with CLR* in the presence of fucoidan (CLR/fucoidan molar ratio of : 20 and : 40) leads to an inhibition of the binding of CLR* to DNA from the molar ratio : 20 Altogether these ... heterotrimeric triple helices of C1q The cationic sequence 14–26 of the A chain, as well as the sequence responsible for the kink of the collagen-like region are shown and the binding of antigen–antibody...
Ngày tải lên: 16/03/2014, 23:20
Báo cáo "On the asymptotic behavior of delay differential equations and its relationship with C0 - semigoup " potx
... satisfies the hypothesis of theorem (2.3) then the solution of Eq.(12) in the case µ = is asymptotic equivalence to the solution of Eq.(12) in the case µ = Ackowledgments This paper is based on the ... solution of Eq.(4) in the case µ = will be asymptotic equivalence to the solution of Eq.(4) in the case µ = 0(in the following we will give µ = 1) .The obtained result of this part is an extention of ... D(A)), then we can investigate the assertion (2.5) for Eq.(13) (see [7, 11, 12]) Applying the process of argument of parts 2.1 and 2.2 to the uniformlly stable and asymptotic equivalence of above...
Ngày tải lên: 22/03/2014, 11:20
THE ENGINES OF HIPPOCRATES From the Dawn of Medicine to Medical and Pharmaceutical Informatics pptx
... and Asklepios and Hygeia and Panaceia and all the gods and goddesses … , —Hippocrates, The Oath” THE MEDICAL RECORD OF THE HUMAN RACE Having made a fast transit of the medical adventure of the ... healthcare systems The healthcare and health insurance systems of today, which are often entrenched and bureaucratic Towers of Babel and yet typically beset by mountains of paper, high rate of medical ... working to improve healthcare Fifth, coupled increasingly to that there is an issue of the healthcare and health insurance systems of today, the often entrenched and bureaucratic Towers of Babel beset...
Ngày tải lên: 22/03/2014, 22:20
Sexuality Issues and Gynecologic Care of Adolescents with Developmental Disabilities potx
... psychologic health of the parents and their youth.1,5,8,11,26,31,33,51–61 The birth of a baby can give parents considerable joy and start them off on a journey of fantasy about the wonderful things their ... understanding that their children are simply reflections of themselves, negating the potential of perfection Children with disabilities also can be in this category, whether dealing with a child with ... ethical, and religious views of parents as these youth seek to understand concepts and perform tasks ‘‘their way’’ consistent with their abilities Much of this is normal adolescent behavior and parents...
Ngày tải lên: 28/03/2014, 14:20
The effect of Qigong on general and psychosocial health of elderly with chronic physical illnesses: a randomized clinical trial doc
... possible to identify the common features of qigong (Brown and Knoferl, 2001) There are three main features of qigong: postures and movement, state of mind, and breathing The aim of practicing qigong ... studied with Tao, had received the transmission of these eight forms and revised them as the Eight-Section Brocades Other theories suggest that the Eight-Section Brocades is a collection of various ... Questionnaire The questionnaire consists of 28 questions on a five-point scale This indicated that the whole spectrum of the five-point scales was utilized in the reflection of quality of life of the participants...
Ngày tải lên: 28/03/2014, 19:21
Guidance on Cancer Services Improving Supportive and Palliative Care for Adults with Cancer ppt
... decisions about the care they receive They may need support from health and social care professionals to help them to make decisions, to plan and evaluate their care, and to explore whether earlier ... assess care and support needs, including needs for palliative care, of each patient and carer at all stages of the patient pathway and in all domains of care understand how to enable patients and carers ... most of their time living in the community • the needs of some patients for a range of specialist services • the importance of forging partnerships between patients and carers and health and social...
Ngày tải lên: 28/03/2014, 23:20
báo cáo hóa học: " Quantification of functional weakness and abnormal synergy patterns in the lower limb of individuals with chronic stroke" pdf
... and extension of the hip, extension of the knee and extension and inversion of the ankle) and the flexion synergy (external rotation, abduction, and flexion of the hip, flexion of the knee, and ... consistent with both the mechanical demands of the task and the physical properties of the musculature of the legs For instance, when asked to generate a maximum knee extension torque, healthy subjects ... flexion/extension, and hip abduction/adduction The arrangement of rows and columns in Table leads to the grouping of the primary joint directions into synergies These synergies are based on the direction of the...
Ngày tải lên: 19/06/2014, 10:20
Báo cáo hóa học: " Caveolin-1 interacts with the Gag precursor of murine leukaemia virus and modulates virus production" docx
... interacts with Gag precursor of MLV Gag-Cav-1 co-localization, the presence of the putative CBD in MA of MLV and the high degree of conservation among γ-retroviruses motivated us to investigate whether ... 622–633 of gp41 [41] The CBD in gp41 is highly conserved within HIV-isolates and SIV lentivirus However, the binding region was mapped to the lentiviral ectodomain of the transmembrane protein and the ... investigate the biological significance of the Cav-1-Gag interaction We reasoned that overexpression of fusion proteins containing the CBD of MA could block the interaction of Gag with endogenous...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" Combined life satisfaction of persons with stroke and their caregivers: associations with caregiver burden and the impact of stroke" potx
... analyzed the life satisfaction of the person with stroke or their caregiver, little is known regarding the life satisfaction within the dyad Life satisfaction of the person with stroke and their caregiver ... perceived life satisfaction of the dyads, the perceived level of impact of the stroke in everyday life for the persons with stroke and the perceived level of burden of care for the caregiver Life Satisfaction ... of 41 of the 81 caregivers were satisfied This is shown in Table Combined life satisfaction and the impact of stroke The results of the impact of stroke in everyday life and the association with...
Ngày tải lên: 20/06/2014, 15:20