the nature and extent of the health inequalities rural and remote areas
Báo cáo khoa học: Structure and topology of the transmembrane domain 4 of the divalent metal transporter in membrane-mimetic environments docx
Ngày tải lên :
16/03/2014, 16:20
... in the presence and
absence of the paramagnetic metal ions. The amplitudes of
the spectra in the presence of the paramagnetic metal ions
were normalized to the least affected cross-peaks. The
paramagnetic ... biology aspects of DMT1 since the
discovery of this gene, there has so far been no structural
characterization of either this integral protein or a segment
of it. Analysis of the structure of membrane ... in
the presence of Gd
3+
at pH 4.0, but the degree to which the
intensities recovered was lower in the presence of Gd
3+
,
particularly for the C-terminal residues, than in the presence
of the...
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Tài liệu Integrative Medicine and the Health of the Public: A Summary of the February 2009 Summit docx
Ngày tải lên :
17/02/2014, 14:20
... stewards of their own health and wellness.
This publication, Integrative Medicine and the Health of the Public:
A Summary of the 2009 Summit, provides an account of the discussion
and presentations ... delivery and more innovative approaches toward im-
proving the health and well-being of our citizens. The concept of the
Summit on Integrative Medicine and the Health of the Public arose from
these ... address the behavioral and social ele-
ments of health care; they focused on the sickest patients in the practice
and went to extraordinary effort to keep these patients out of the hospital;
and they...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
Ngày tải lên :
14/02/2014, 19:20
... between the
Leu residues from v-KIND and MAP2 contributes to
the interaction between the two proteins.
In conclusion, the present study has clarified the
structural and functional importance of the ... vector,
respectively. The present study was supported by
grants from the Japanese Ministry of Education,
Culture, Sports, Science and Technology; the Japan
Society for the Promotion of Science; and the Japan
Science ... and 482) and
one Thr residue (amino acid 487) were well conserved
in the KIND2 of v-KIND in all species analyzed,
although not in the other KINDs. To investigate the
possible involvement of these...
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Tài liệu Báo cáo khoa học: Effect of ionic strength and oxidation on the P-loop conformation of the protein tyrosine phosphatase-like phytase, PhyAsr docx
Ngày tải lên :
18/02/2014, 18:20
... acid. In addi-
tion to these contacts, there is a 1.82 A
˚
contact
between Gly255 C
a
and O
d
2 of the oxidized cysteine.
To further understand the structural consequences of
the P-loop transition ... bonds
with the P-loop main chain and O
d
1 and O
d
2.
Although there are movements in the P-loop, there
are no other major conformational changes in the
protein. Most notably, the loop containing the ... test whether the move-
ment of the P-loop in PhyAsr is due to oxidation of
the catalytic cysteine, we oxidized crystals of PhyAsr
Table 1. Effect of ionic strength on the hydrolysis of InsP
6
by
PhyAsr....
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Tài liệu Ownership of Mutual Funds, Shareholder Sentiment, and Use of the Internet, 2011 pdf
Ngày tải lên :
19/02/2014, 09:20
... telephone with the member
of the household who was the sole or co-decisionmaker most knowledgeable about the household’s savings and
investments. The standard error for the 2011 sample of households ... 35
37
50
5252
32
Age of head of household
1
1
Age is based on the age of the sole or co-decisionmaker for household saving and investing.
2
For the complete time series of data from 1994 through ... U.S. households
3
Age of head of household
1
1
Age is based on the age of the sole or co-decisionmaker for household saving and investing.
2
For the complete time series of data from 1994 through...
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Tài liệu Ownership of Mutual Funds, Shareholder Sentiment, and Use of the Internet, 2012 pdf
Ngày tải lên :
19/02/2014, 09:20
... conducted over the telephone with the
member of the household who was the sole or co-decisionmaker most knowledgeable about the household’s savings
and investments. The standard error for the 2012 ... in the appendix.
12
See FigureA10 in the appendix.
13
Some of the variation in the mutual fund favorability
rating across the age groups is affected by differences in
the frequency of the ... U.S. households
3
Ag
e of head of household
1
1
Age is based on the age of the sole or co-decisionmaker for household saving and investing.
2
For the complete time series of data from 1994 through...
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Tài liệu Báo cáo khoa học: Long-distance interactions between enhancers and promoters The case of the Abd-B domain of the Drosophila bithorax complex pdf
Ngày tải lên :
20/02/2014, 01:20
... However, when the combination of the PTS and the bound-
ary is placed 3Â to one of the reporter genes, the enhancer is
targeted to one or the other promoter over the boundary (lower
panel). E1 and E2: ... later than in the case of
the histone gene cluster [10]. This difference in the tim-
ing of somatic pairing perhaps reflects the difference
between the complexities of the regulation of the two
systems: ... locate and physically approach their
proper target promoter in the viscous environment of
the nucleus.
Somatic pairing of chromosomes and
the regulation of Abd-B
A peculiarity of Drosophila is the...
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Tài liệu Báo cáo Y học: Importance of the amino-acid composition of the shutter region of plasminogen activator inhibitor-1 for its transitions to latent and substrate forms pdf
Ngày tải lên :
22/02/2014, 07:20
... affecting the rate of passage
of the RCL through the gate region. Based on the amino-
acid sequence of the RCL and b strand 5A being directly
continuous, it may be proposed that movements of the RCL
during ... b strand 6A and the backbone of
Asn171 in the a helix F/b strand 3A loop.
Note:
SWISSPDB VIEWER uses the same
signature for a helices and the short 3
10
-helix
found in the a helix F/b strand ... effects of the K335A substitution in the absence
and presence of vitronectin, we propose that the
conformational change of PAI-1 following the binding of
vitronectin implicates a reorientation of the...
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Báo cáo khoa họcRe-engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the coenzyme specificity of the wild-type enzyme docx
Ngày tải lên :
06/03/2014, 00:20
... than the true value, underlining the impact of quite a
small level of contamination on these results.
Reassessment of the effects of the mutations on
coenzyme specificity
In view of the dramatically ... moiety of the coenzyme resulting
from splitting off the nicotinamide ring, suggesting
that the covalent bond between the nicotinamide and
the ribose of the coenzyme is particularly labile. The
signal ... identification of NAD
+
peak
Isolation and mass spectroscopic analysis confirmed
the identity of the contaminant. Comparison with the
spectrum of an authentic NAD
+
sample revealed
total similarity of the...
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Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf
Ngày tải lên :
06/03/2014, 11:20
... region of the
1
H,
15
N-HSQC spectrum of
the C-terminal domain of human eRF1 illustrating the
presence of two conformational states of the protein.
Fig. S2. Plot of the number and distribution of the
NOEs ... sizes of the
relative populations and possibly the rate of conformer
interconversion are sensitive to the environment of the
domain.
For the great majority of the residues in the minido-
main, the ... for the determination
of the structures of the conformers of the C-domain.
The dipolar couplings provided long-distance informa-
tion on the global folding of both conformers.
The structure of the...
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Report of the Special Rapporteur on the promotion and protection of the right to freedom of opinion and expression, Frank La Rue* ppt
Ngày tải lên :
06/03/2014, 21:20
... so, usually the judiciary, for the purpose of protecting the rights of others, for
example to secure evidence to prevent the commission of a crime, and must respect the
principle of proportionality.
40
... technologies, for the exercise of the right to freedom of
opinion and expression, including the right to seek, receive and impart information and the
relevance of a wide diversity of sources, as ... freedom of opinion and expression, but also a
range of other human rights, and to promote the progress of society as a whole. Chapter III
of the report underlines the applicability of international...
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Báo cáo khoa học: Solution structure and backbone dynamics of the XPC-binding domain of the human DNA repair protein hHR23B docx
Ngày tải lên :
07/03/2014, 17:20
... further our knowledge with
respect to the mechanisms of action of these proteins,
it is crucial that we define the precise boundaries of
the STI1-homologous domain and compare the struc-
tures of ... structure. The quality of the struc-
tures was assessed using the refined energy terms and the
procheck program [37]. The surface electrostatic potential
distribution of the best overall model of XPCB–hHR23B
was ... fitting, and those of the
15
N-
1
H NOEs were obtained
from the difference of two independent experiments. The
values of error were adjusted for the proper tensor2 analy-
sis, by increasing of the...
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Báo cáo khoa học: Sequences downstream of the transcription initiation site are important for proper initiation and regulation of mouse ribonucleotide reductase R2 gene transcription ppt
Ngày tải lên :
08/03/2014, 02:20
... by the lower arrow to the left
of the autoradiograph). All bands were quantified using the Scion
Image program and the ratio between the upper and lower bands for
each assay is presented below the ... to the in vitro transcription reac-
tions. All bands were quantified using the Scion Image program. The
upper numbers represent the intensity of each band normalized to the
band in lane 1. The ... addition of the probe;
lanes 8–10, the same as 5–7, but with monoclonal antibodies against
mouse R1. The numbers under the gel represent the intensity of each
band normalized to the band in lane...
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Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt
Ngày tải lên :
08/03/2014, 10:20
... comparison of the effects of rough
andsmoothLPSsofE. coli, both in the presence and
absence of EDTA (Fig. 1). The rate of oxidation was
increased in the presence of the LPSs of both the smooth
and rough ... measure
of the rate of oxidation of oxyHb.
RESULTS
The effect of pH on the auto-oxidation of cross-linked Hb
was studied. The rate of decrease of the concentration of
oxyHb increased as the pH ... of
oxidation in the presence of EDTA.
A comparison of rough and smooth LPSs of E. coli and
S. minnesota in the presence of EDTA revealed that both in
the presence and absence of EDTA, the oxidation of cross-
linked...
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