the moral standing of the human embryo
The Human Embryo Edited by Shigehito Yamada and Tetsuya Takakuwa doc
Ngày tải lên :
30/03/2014, 23:20
... 1914, became the first director of the Department of Embryology at the Carnegie Institution of Washington, in Baltimore, MD The collection grew up at a rate of about 400 The Human Embryo specimens ... by the zona pellucida The second maturation division of the oocyte completes as the sperm penetrates the egg (fertilization) The sperm head and the nucleus of the oocyte then swell to form the ... grows to cover the ventral part of the forebrain (stage 13) It will form the forehead (frontal part of the FNP) and the primordial mouth and nose (nasal part of the FNP) By the end of the 4th developmental...
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Tài liệu Báo cáo khoa học: Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells pptx
Ngày tải lên :
19/02/2014, 18:20
... identified [17,19] The smaller isoforms correspond to N-terminal deletions of the fulllength 140 kDa protein The physiological role of the guanine nucleotide exchange activity of the truncated forms ... of expected size (Fig 1B) The primer sequences are located at the 5¢ end (ON361, ON360 and ON359) and in the middle (ON357 and ON358) of the human Ras-GRF1 nucleotide sequence Sequencing of the ... serotonin The 60 kDa isoform of Ras-GRF1 seems to be expressed at a higher level than the 140 kDa isoform The serotonin-induced increase in phosphorylation of both isoforms was reduced by the coexpression...
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HUMAN RIGHTS AND THE MORAL RESPONSIBILITIES OF CORPORATE AND PUBLIC SECTOR ORGANISATIONS pptx
Ngày tải lên :
30/03/2014, 02:20
... perspective of the perpetrator rather than that of the victims, the difficulty of perceiving evil in one’s own time, the euphemisms of technical language, the dehumanising impact of collective ... rights and other interests of those involved in it A large part of the public interest that justifies the protected legal status of corporations consists of the protection and furtherance of human ... question of whether these duties of corporations arise simply by way of default, as a result of the failures of governments to take appropriate action, or whether they arise as a result of the immense...
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báo cáo hóa học:" MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells" doc
Ngày tải lên :
18/06/2014, 15:20
... Loss -of- function of the miR-17-92 cluster resulted in smaller embryos and immediate postnatal death of animals [67], which could due to the deficiency of their roles in the development of the ... are names of human embryonic stem (hES) cells lines P denoted the number of passages of the cell lines H9-EB denoted embryoid body (EB) prepared from cell line H9 and the day indicates the time ... names of hES cells lines P denotes the number of passages of the cell lines H9-EB denotes embryoid body (EB) prepared from cell line H9 and the day indicates the time in culture HMVEC = human...
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Báo cáo y học: "Elucidating the molecular characteristics of organogenesis in human embryos" potx
Ngày tải lên :
09/08/2014, 20:22
... ated to compare the gene-expression profile of human embryos with that of human embryonic stem cells (hESCs) maintained in culture They found that approxi mately 20% of the genes in the clusters ... such as the gene-expression profile of the human gastrula, will help complete the molecular characteri a z tion of early human embryogenesis These valuable resources will help elucidate the basic ... whether these findings implicate important species-specific differences in the regulation of organ development Charting the loss of pluripotency Fang et al also took advantage of the dataset they...
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Báo cáo y học: "Human embryonal epithelial cells of the developing small intestinal crypts can express the Hodgkin-cell associated antigen Ki-1 (CD30) in spontaneous abortions during the first trimester of gestation" ppsx
Ngày tải lên :
13/08/2014, 22:22
... sections, taking into account that the ratio of the area of the intestinal stroma to the area of surface epithelium Page of (page number not for citation purposes) Theoretical Biology and Medical ... seminoma [21] and in the seminomatous components of 7/14 cases of mixed germ cell tumours of the testis [22] Suster et al detected the CD30 antigen in 6/25 yolk sac tumours of the testis and mediastinum ... in the neighbouring intestinal stroma in cases of either spontaneous or voluntary/therapeutic abortion in comparison to the 8th and 10th gestational weeks The differences among the numbers of...
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Báo cáo y học: "he signature of long-standing balancing selection at the human defensin β-1 promoter" pptx
Ngày tải lên :
14/08/2014, 21:20
... However, as the authors note, the introduction of HIV1 in human populations is relatively recent and cannot, therefore, account for the maintenance of balanced polymorphisms in the region; therefore, ... analysis of DEFB1 haplotypes revealed the presence of two clades separated by long branches approximately dating back to the time when the human and chimpanzee lineages split Altogether, these features ... modulate the fitness of subjects carrying either allele Unfortunately, little information is available concerning the early epidemiological history of our predecessors; indeed, the timing of human...
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The derivation, propagation, storage and gene expression of human embryonic stem cells on human feeders
Ngày tải lên :
16/09/2015, 15:55
... more of them Although these cells have the potential to give rise to the entire organism, they not have the capability to self-renew and by strict definition therefore, the totipotent cells of the ... form the zygote that retains the ability to make a new organism thereby ensuring the continuation of the germ line In fact the zygote is at the top of the hierarchical stem cell tree being the ... events of human development, the causes of early pregnancy loss and certain aspects of embryonic ageing hESCs may also prove useful in the study of the toxicological effects of new drugs Embryonic...
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Báo cáo y học: "Expression of hMSH2 protein of the human DNA mismatch repair system in oral lichen planus"
Ngày tải lên :
03/11/2012, 09:54
... almost all of the OLP epithelium The count was performed by two investigators without knowledge of whether the samples were control or experimental The total number of basal and suprabasal epithelial ... PermountTM Negative controls consisted of omission of the primary or the secondary antibody or primary incubation in the presence of non-immunized rabbit serum instead of the primary antibody Cell quantification ... of hMSH2 Therefore, the reduced expression of hMSH2 protein could make the epithelium of OLP more susceptible to DNA mutation, making it prone to oral squamous cell carcinoma development Further...
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Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"
Ngày tải lên :
03/11/2012, 10:01
... applied to humans The purpose of this paper is to consider the potential for applying the available genetic modification (GM) technologies to the goal of achieving human germline gene therapy If ... a variety of routes including pronuclear microinjection and SMGT [74, 75, 76] In the context of human germline gene therapy, such vectors offer the potential advantage of eliminating the threat ... probably be usable with human zygotes, the major inherent problems of the method render it less than ideal for human germline gene therapy A major problem is the relatively low rate of transgene integration:...
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A STUDY ON THE TRANSLATION OF ENGLISH HUMAN RESOURCE MANAGEMENT TERMS INTO VIETNAMESE
Ngày tải lên :
11/12/2013, 23:55
... study, scope of the study, and method of the study are presented The Reason of the study mentions the reason why I choosing this thesis The Aims of the study lists all the aims that the paper has ... achieve The Methods describe the ways with which the study was carried out The Scope of the study clarifies the areas and subjects which was studied The Design gives the outline of the main parts of ... overall look on Human Resource Management, then the overview of Human Resource Management terms The last one is the main part of the study which presents the study on translating Human Resource...
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Contrastive analysis on english and vietnames proverbs referring to parts of the human body
Ngày tải lên :
12/12/2013, 00:03
... referring to parts of the human body The position of proverbs referring to part of the human body Parts of the human body 21 21 21 The classification of parts of the human body according ... diversified (multiple form) The classification of parts of the human body according to the position In the system of the proverbs, the system of words referring to parts of the human body is divided ... functions: the function of comprehension, the aesthetic function, the function of education, the words about parts of human body are used to form the meaning of proverbs, therefore, they become...
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The transference of meaning through class of words denoting parts of the human body in english and vietnames
Ngày tải lên :
18/12/2013, 21:45
... earth The hand of a child - The hand of a lock The heart of a man - The heart of a matter 37 The tongue of a man - The tongue of a shoe The tooth of a person - The tooth of a comb The head of a ... hands of a farm 13 The heel of a person - The heel of the hand 14 One's leg - The leg of a trip 15 One's brain - The brains of a family 16 The bosom of a person - The bosom of the church 17 The ... part There are various types of similarity: - The similarity of shape E.g: The teeth of a saw, the head of a cabbage - The similarity of position E.g: The tail of procession - The similarity of...
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Tài liệu Báo cáo khoa học: Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1 docx
Ngày tải lên :
15/02/2014, 01:20
... product of PRPP from the crystallization solution ing 81 compounds of substrates, products and regulators of other enzymes in the human nucleotide metabolism (Table S1) The library can then be ... interacts with both O6 and N7 (Fig 1C) The 2¢OH of the ribose is hydrogen bonded to the main chain and the side chain of Asp142 (Fig 1C) Both hydroxyl groups of the ribose are involved in coordinating ... ligands for enzymes in the human nucleotide metabolism These were selected as substrates, intermediates and products of other enzymes in the human nucleotide metabolism The library was screened...
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Tài liệu Báo cáo khoa học: Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor c pptx
Ngày tải lên :
18/02/2014, 16:20
... Given that the roles of these residues definitely confirm each other, the difference in their significance might be attributable to the importance and ⁄ or necessity of the receipt of the phenol-hydroxyl ... rationale for the major role of Arg316 in arresting the ligand When the amino acid sequences of the LBD of all the NRs were aligned to that of ERRc, it became noticeable that 26 receptors among the total ... ligand-binding pocket of the ERRc The proximity of each amino acid residue (within a ˚ distance of A) to BPA is shown in the boxes depicting the a-helices The portrait was originated from the X-ray crystal...
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Tài liệu Báo cáo khoa học: Roles of the human Rad51 L1 and L2 loops in DNA binding doc
Ngày tải lên :
19/02/2014, 06:20
... monomer of poly(dT), showing that the changes were mainly due to the binding of the first DNA, while the binding of the second DNA had less influence (Fig 5A) To ensure that the estimation of the protein:poly(dT) ... in these eukaryotic and archaeal proteins (Fig 1A) Like the case of bacterial RecA, the L1 and L2 loops of the eukaryotic Rad51 proteins face A Roles of the HsRad51 L1 and L2 loops inside of their ... precision of 3% The changes occurring upon the addition of the element are noted in parentheses ND, not determined Y Matsuo et al ciation, like the case of Tyr188 of Xenopus laevis Rad51 [28] These...
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Tài liệu Báo cáo khoa học: Multiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11⁄hippostasin ppt
Ngày tải lên :
19/02/2014, 06:20
... type of KLK11, isoform 2, despite the presence of exon 1c The secretory pathways of KLK11 isoforms appeared to differ, although both isoforms were secreted from cells Hence, the promoter use of the ... the isoform of translation products through the determination of the first exon in KLK11 mRNA (summarized in Fig 2A) Detection of the first exon in each KLK11 mRNA reflects the promoter use in the ... a part of isoform mRNA The third exon, exon 1c, extended from +1379 to +1454 The noncoding exons of exons 1a and 1c contributed to the 5¢ nontranslated region of isoform mRNA in which the common...
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Tài liệu Báo cáo khoa học: Topology, tinkering and evolution of the human transcription factor network doc
Ngày tải lên :
19/02/2014, 07:20
... functionality and phylogeny However, the nature of the connections between these factors needs to be understood at the level of the protein domain The global properties of the HTFN topology are partially ... graph of N ¼ 230 interacting human TFs was obtained (Fig 1) This can be understood as the architecture of the regulatory backbone It provides a topological view of the interaction patterns among the ... features of each group self-interaction is understood as the interaction between proteins of the same type, i.e homo-oligomerization, regardless of the number of monomers involved To evaluate their...
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Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx
Ngày tải lên :
19/02/2014, 16:20
... selected subsets of T cells [2,18,19] Earlier studies on human CD1d expression showed that this unconventional MHC class I molecule localizes in the cytoplasm of human epithelial cells of the gastrointestinal ... decrease in the percentage of cells in the S and G2 ⁄ M phases of the cell cycle (Fig 3B) In a total of seven separate determinations, a statistically significant decrease in the percentage of dividing ... proliferation of stelleate cells and synthesis of collagen [36,37], the in vitro data presented here may be relevant for understand some of the complex mechanisms responsible for the development of fibrosis...
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