... the way to the beginning of the experiment [23] (Fig 2C), which means that the observed lag time depends inversely on the growth rate of fibrils, as well as the nucleation rate A compilation of ... can impact the outcome of the struggle for monomers between several types of fibril due to modulation of their nucleation and exponential growth rates [23] Interestingly, another class of proteins ... fibrils The key to the properties of amyloid assemblies lies in the regularity and repetitiveness of their underlying molecular architecture of intermolecular b-strands stacked perpendicular to the...
Ngày tải lên: 23/03/2014, 03:20
... angle between the direction of the magnetic field H and the direction of the magnetization M of the bar magnet [11] The product pl is the magnetization M of the bar [13] The work done by the torque ... under the influence of an applied uniaxial tensile load The plot is elongated in the direction of magnetic anisotropy which in the case of the 0.03% deformation is also the direction of the applied ... minimum at the same time Formation of a certain magnetic domain configuration is the outcome of the sum of the five basic energies being minimized, although the energies themselves may not be at their...
Ngày tải lên: 04/06/2014, 15:18
schrodinger's rabbits the many worlds of quantum
... deflected The greater intensity increased the number of photon-particles, but not the amount of momentum carried by each On the other hand, changing the color of the light did change the angle ... demonstrated using the simplest particles of which our universe is built, the photon and the electron, the basic units of light and matter Measuring the spin of an electron, or the polarization of a photon—scratching ... only if the experiment is done in the dark The brighter the light shone on the electrons, the fainter the interference pattern produced This washing out of the pattern has nothing to with whether...
Ngày tải lên: 05/06/2014, 11:21
What are the possible causes of child abuse? pot
... to fray the nerves of the parents Further demands from the children at home might cause a nervous reaction on the part of the parents Some parents, in order to escape from the demands of the children, ... hand them over to child-minders This handling over of responsibility does not solve the problem All too often the minders are suffering the same difficulties of making a living and take on the ... simply because they not have the stress of city-living They are still closer to nature and this has the effect of making life easier and simpler Children are less demanding as there are less...
Ngày tải lên: 21/07/2014, 20:20
báo cáo khoa học: " Harm reduction, methadone maintenance treatment and the root causes of health and social inequities: An intersectional lens in the Canadian context" ppt
... policies) “can inhibit the capacities of some people” at the same time as they expand the options of others (p.10) [68] Many of the participants in our study described the ways in which their lives have ... assisted with the drafting of the manuscript CV assisted in the interpretation of the data and the drafting of the manuscript VJ participated in data analysis and interpretation of the data and ... account the social context of the group It places the focus on society’s response to the individual as a result of the confluence of various factors and does not require the person to slot themselves...
Ngày tải lên: 11/08/2014, 18:20
Báo cáo y học: " Paper reports overview: The many guises of respiratory support, microalbuminuria and delirium" pdf
... van den Berg-Huysmans AA, Huisman MV: Embolus location affects the sensitivity of a rapid quantitative D-dimer assay in the diagnosis of pulmonary embolism Am J Respir Crit Care Med 2002, 165:345-348 ... reliability of the confusion assessment method for the intensive care unit (CAM- ICU) JAMA 2001, 286:2703-2710 Tsuchiya, M, Asada A, Kasahara E, Sato EF, Shindo M, Inoue M: Antioxidant protection of propofol ... therapy in infants with acute bronchiolitis Pediatrics 2002, 109:68-73 Abid O, Sun Q, Sugimoto K, Mercan D, Vincent JL: Predictive value of microalbuminuria in medical ICU patients: results of...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "The leading causes of death after burn injury in a single pediatric burn cente" docx
... participated in the design of study and retrospective review CCF participated in the design of the study, and drafting of the manuscript DLC participated in the design of the study, drafting the manuscript, ... JOL participated in the design of the study, drafting the manuscript, and was clinically responsible for the patients REC participated in the design of the study, and drafting the manuscript GAK ... outlined the design of study, drafting the manuscript, and was clinically responsible for the patients HKH participated in the design of the study, drafting the manuscript, and performed the autopsies...
Ngày tải lên: 13/08/2014, 20:21
lepler - the many panics of 1837; people, politics, and the creation of a transatlantic financial crisis (2013)
... relationships with other mercantile men in distant places for their own 10 The Many Panics of 1837 profits The particular urban geographies of three of the most important cities in the trade of the 1830s ... traces the evolution of this event into competing versions of the Panic of 1837 that all lost sight of the experience of panic But this tale of panic’s disappearance is the end and not the beginning ... Center, the Center for History and Economics at Harvard University, the University of Georgia, the Culture of the Market Network at the University of Oxford, the University of Liverpool, the University...
Ngày tải lên: 01/11/2014, 12:16
Tài liệu Misconceptions about the Causes of Cancer pptx
... People and the Press, each of the top 10 stories of public interest in the United States during 1999 were about bad news With the exception of the outcome of the American election, the birth of septuplets ... opinions expressed by them are, therefore, their own and not necessarily reflect the opinions of the members or the trustees of The Fraser Institute Printed in Canada National Library of Canada Cataloguing ... policy debates The books in the series are full of valuable information and will provide the interested citizen with a basic understanding of the state of the science, including the many questions...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Déjà Vu All Over Again: The Causes of U.S. Commercial Bank Failures This Time Around* docx
... write off half the value of its bad loans There were 148 such banks as of year-end 2009 10 Thus, we place 265 (117 + 148) in the FAIL category 11 10 It is worth noting that of the 57 of the 74 ... impose a form of right-hand censoring; but, of course, the identities of the banks in this latter group could not be known as of year-end 2009 Rather than ignore them, we estimate their identities ... Summary of Univariate Comparisons of Failed and Surviving Banks The results of t-tests on the differences in the means of the explanatory variables for earlier years with respect to the 2009...
Ngày tải lên: 16/02/2014, 03:20
Tài liệu Misconceptions About Environmental Pollution, Pesticides and the Causes of Cancer doc
... number of states Many credit NCPA studies of the Medicare surtax as the main factor leading to the 1989 repeal of the Medicare Catastrophic Coverage Act NCPA forecasts show that repeal of the Social ... significant role in the prevention and repair of DNA damage, and thus are important to the maintenance of long term health Deficiency of vitamin B12 (found in percent of the U.S population) causes a functional ... plants themselves.” On the contrary, 99.9 percent of the chemicals humans ingest are natural The amounts of synthetic pesticide residues in plant foods are insignificant compared to the amount of...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc docx
... [1,14] The lack of hydroxylation of vitamin D3 at position 22 now provides a clear explanation for the inability of P450scc to cleave the side chain of vitamin D3 Hydroxylation of the side chain of ... of 17a,20,23-trihydroxyvitamin D3 (A) Expansion of proton– carbon HSQC of 20,23-dihydroxyvitamin D3 showing the three methine groups (B) Expansion of the same region of 17a,20, 23-trihydroxyvitamin ... difference between the metabolism of vitamin D3 and cholesterol by P450scc is that the dissociation of intermediates occurs for the metabolism of vitamin D3, but not for the metabolism of cholesterol...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Glucuronate, the precursor of vitamin C, is directly formed from UDP-glucuronate in liver pptx
... 20%, despite the presence of ATPMg It is shown below that this is due to loss of the inhibitory effect of ATP-Mg, consequent to the removal of a heat-stable cofactor present in the highspeed ... tested in the presence of 10 mM ATP-Mg and in the absence (black bars) or presence (grey bars) of mM metyrapone (A) The effect of the heated high-speed supernatant was further analysed in the absence ... oriented towards the lumen of the vesicles and that disruption of the vesicular membrane increases accessibility to UDP-glucuronate Some of the detergents exerted inhibition of the enzymatic activity...
Ngày tải lên: 19/02/2014, 07:20
The analysis of vitamin c
... Using a 0.1000-g sample of pure ascorbic acid, 25.32 mL of I2 were required to reach the starch end point a What is the molarity of the iodine solution? b What is the titer of the iodine solution ... endpoint a What is the concentration of vitamin C in the juice in mg vitamin C/100 mL of juice (mg/ 100 mL)? b What quantity of juice will provide the RDA amount of vitamin C (mL)? Experiment 3 ... add mL of starch indicator to the first ascorbic acid sample and titrate with the iodine solution Note the change of the I2 color as you swirl the flask gently and continuously during the titration...
Ngày tải lên: 03/03/2014, 11:49
THE FINANCIAL CRISIS INQUIRY REPORT - Final Report of the National Commission on the Causes of the Financial and Economic Crisis in the United States docx
... Development, the Office of the Comptroller of the Currency, the Office of Federal Housing Enterprise Oversight (and its successor, the Federal Housing Finance Agency), the Office of Thrift Supervision, the ... to the President, the Congress, and the American people the results of its examination and its conclusions as to the causes of the crisis More than two years after the worst of the financial crisis, ... at the end of chapters in Parts III, IV, and V of this report The subject of this report is of no small consequence to this nation The profound events of and were neither bumps in the...
Ngày tải lên: 06/03/2014, 09:22
Báo cáo khoa học: Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase doc
... characterized up to now, and the first example of a specific, vitamin C biosynthetic enzyme of bacterial origin Further studies will be necessary to elucidate the role of the Rv1771 l-gulono-1,4-lactone ... and another vitamin C-related enzyme, the GDP-mannose-3¢,5¢epimerase [9] The presence of multiple GST-containing bands of about 30 kDa (Fig 1, lane 5) suggests that an important portion of the fusion ... the host proteases On the other hand, attempts to produce a His-tagged version of the The Rv1771 gene of M tuberculosis encodes a 428 amino acid protein (Fig 2) that shows 32% identity with the...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism docx
... that are present on MS3 of vitamin D3 There was insufficient product P2 from the action of P450scc on vitamin D3 to perform NMR and therefore a full scan mass spectrum of the product was obtained ... In fact, the yield of dihydroxy product was only 4% of the vitamin D3 load, compared with a 16% yield of 20-hydroxyvitamin D3 This is in contrast to the P450scc-mediated conversions of cholesterol ... change there is also a significant downfield shift (D ¼ 0.32 p.p.m) of the CH3-21 signal The same shift had been reported for a preparation of 20-hydroxyvitamin D3 [18] The difference between the...
Ngày tải lên: 07/03/2014, 21:20
Bacteria are often maligned as the causes of human and animal disease (like this one, Leptospira, which causes serious disease in livestock)
... as the Democratic Republic of Congo In these two instances the mortality rate was between 50 –90% Following those epidemics, Ebola hit Africa in many other instances the worst yet being in the ... Since the September 11 bombings in the United States, the locality of this virus has become less isolated as the threat of bioterrorism looms large The Ebola virus is now on the “A” list ... This concept of can be used to explain the world’s shockingly small response to the Ebola Virus Because there was little travel to that region by people of more developed countries, there was...
Ngày tải lên: 15/03/2014, 13:09
Misconceptions About the Causes of Cancer ppt
... the VSD The VSD was approximated by the MTD/740,000 for rodent carcinogens (94) For 90% of the carcinogens, the MTD/740,000 was within a factor of 10 of the VSD (Table 5) This is similar to the ... thus protect us against the natural world of mutagens as well as the small amounts of synthetic chemicals (60, 88-90) There are validity problems associated with the use of the limited data from ... smoke may damage both their somatic DNA and the DNA of their sperm When the level of dietary vitamin C is insufficient to keep seminal fluid vitamin C at an adequate level, the oxidative lesions...
Ngày tải lên: 22/03/2014, 16:21
Causes of the Collapse of the Icelandic Banks - Responsibility, Mistakes and Negligence pdf
... that the intervention of the banks in the trading of their own stock changed the perception the shareholders at that time had of the value of their stock The shares were thus believed to be of ... Governors of the CBI often chose less contractionary policy than the chief economist of CBI suggested It is noteworthy that the minutes of the meetings of the Board of Governors of the CBI not ... cars The increase in the current account deficit for that reason is temporary and the deficit will fall rapidly by the end the end of the expendisonthe end of the end of the expansion Weakening of...
Ngày tải lên: 22/03/2014, 23:20