... at the last base, G to A, abolished the interaction of HIPPI, so the last motif would not interact with HIPPI. The other two motifs might be the target of HIPPI. In the upstream sequence of the Table ... positions of the motifs are indicated by distance from the transcription start site (TSS). The position upstream of the TSS of any gene is denoted by ‘–’ followed by the distance from the TSS. In the caspase-8 ... confirmed the in vitro result that mutation of the motif abolished the binding of HIPPI to the specific sequence of the caspase-1 gene upstream sequence, and the increased expression of caspase-1...
Ngày tải lên: 07/03/2014, 10:20
... in the presence of KCl. Considering also the 3D structure of CDase I-5, the analysis of the quaternary state of CDase I-5 revealed Fig. 8. Fluorescence spectra of CDase I-5. (A) - - - -, the ... the adjacent monomer, of which G538 forms a hydrogen bond to the carbonyl oxygen of M51. Two residues at the N-terminus (H49 and H89) of a subunit were located close to the C-domain of the other ... either in the secondary structure of the protein according to far-UV CD data or in the size of the protein determined by size- exclusion HPLC. They suggested that the change might occur either...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo " On the set of periods for periodic solusions of some linear differential equations on the multidimensional sphere $S^n$ " docx
Ngày tải lên: 14/03/2014, 13:20
Báo cáo Y học: Introducing Wilson disease mutations into the zinc-transporting P-type ATPase ofEscherichia coli The mutation P634L in theÔhingeÕ motif (GDGXNDXP) perturbs the formation of the E2P state pdf
... than the wild-type both in the absence a nd in the p resence of Fig. 3. Normalized zinc-dependent ATPase activity of the wild-type and mutated enzymes. TheATPaseactivity(percentageoftheactivityofthe wild-type) ... The effect of 30 l M Zn 2+ on the P i -phosphorylation of the wild-type and the P401L enzymes (gray columns). Note that the maximal phosphorylation of the P401L mutant is only 8% of the wild-type ... possible that the tolerance for the s ubstitutions at this site is related to the size and hydrophobicity of the substituting side chain. Inspection of a theoretical model of the Ca-ATPase in the E 2 state...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo khoa học: Internalization of the human CRF receptor 1 is independent of classical phosphorylation sites and of b-arrestin 1 recruitment potx
... with the Substance P receptor [25]. Detachment of the cells from the surface of the culture dish could r eflect disassembly of the actin cytoskeleton in the me mbrane regions as a consequence of ... both the cAMP and the PLC pathway [22], the second messenger product of either or both of these pathways could be invo lved in agonist-stimulated internalization of this receptor. The effect of ... f 125 I-labelled sauvagine could be observed in the presence of any of these inhibitors. These findings indicate that neither the activation of PKA nor the activation of PKC is necessary for agonist-induced...
Ngày tải lên: 30/03/2014, 15:20
báo cáo hóa học:" The occurrence of osteoarthritis at a minimum of ten years after reconstruction of the anterior cruciate ligament" pdf
... osteoar- thritis of 1 grade in 52% of the patients, 35% of the patients had an increase of 2 grades and 3% of the patients had an increase of 3 grades. (Table 4, 5 and 6) 10 % of the patients had ... per- formance, the score may appear too high, and will reflect the actual function of the knee as well as the satisfaction of the patient. The Lysholm score has never been validated for the purpose of following ... test). These patients were considered at high risk of further knee injury due to the degree of laxity and the desired level of activity [27]. In order to minimise the development of arthrofi- brosis,...
Ngày tải lên: 20/06/2014, 01:20
báo cáo hóa học:" The psychological context of quality of life: a psychometric analysis of a novel idiographic measure of bladder cancer patients’ personal goals and concerns prior to surgery" pot
... major motivat ional theme as it demon- strates yet another dimension of the QOL Appraisal Profile and further helps e lucidate the nuances o f the profile. The major theme of reaching an event/ milestone ... needed. Other patients c om- pleted the Quality of Life Appraisal Profile and other measures during the time that they were receiving neo- adjuvant chemotherapy. In order to see whether these confounders ... College of Medicine of Yeshiva University, Bronx, New York, USA. Authors’ contributions BAM assisted in the organization/administration of the study, gathering of the data, analysis of data,...
Ngày tải lên: 20/06/2014, 15:20
Báo cáo hóa học: " Letter to the Editor Remarks on “On a Converse of Jensen’s Discrete Inequality” of S. Simic ´" doc
... between Theorems 2 and 8;thatis, in Theorem 2,thedifferentiability of a function φ is not emphasized which is used in the proof. Also, the proof of Theorem 2 is completely analogous to the proof of ... 6,page37. Therefore, w e will look back only on case i of Theorem 1. By applying Theorem 3 to the function Fx, yx/y, we obtain the following result. Theorem 7. Suppo se that all the conditions of ... a discrete version of Theorem 8. It is obvious that the main results presented in 2 are special cases of results given in 3, Theorem 1, Corollary 1, Remark 2. Note that there is a difference...
Ngày tải lên: 21/06/2014, 05:20
Báo cáo hóa học: "Research Article Existence of Solutions for a Class of Elliptic Systems in RN Involving the p x , q x -Laplacia" pptx
... and Mathematical Theory, vol. 1748 of Lecture Notes in Mathematics, Springer, Berlin, Germany, 2000. 13 V. V. Zhikov, “Averaging of functionals of the calculus of variations and elasticity theory,” ... they apply the mountain pass theorem to get the nontrivial solutions of the the system. In 30, the author obtains the existence and multiplicity of solutions for the following problem: − div|∇u| px−2 ∇u ∂F ∂u x, ... υ zdx . 3.26 Since the restriction operator is continuous, then u n , n u, in W 1,px 0 B r ì W 1,qx 0 B r . Because of the compactness of F r , the first expression on the right-hand side of the equation tends...
Ngày tải lên: 22/06/2014, 03:20
THE THIRTEENTH CENTURY.—THE MANOR AT ITS ZENITH, WITH SEEDS OF DECAY ALREADY VISIBLE.—WALTER OF HENLEY pdf
... 2,700 acres, from the preponderance of arable, the chief source of income to the lord was from the grain crops; other sources may be seen from the following table of the lord& apos;s receipts ... 3d. The rector of the parish had part of a furrow, i.e. one of the divisions of the common arable field, and paid 2d. a year for it. Another tenant held a cottage in the demesne under the obligation ... of keeping two lamps lighted in the church. Another person was tenant-at-will of the parish mill, at a rent of 40s. a year. The rest of the tenants were villeins or cottagers, thirteen of the...
Ngày tải lên: 29/06/2014, 15:20
báo cáo khoa học: "The role of 18F-FDG-PET/CT in the preoperative staging and posttherapy follow up of gastriccancer:Comparison with spiral CT" docx
... accepted the cut off SUVmax value as 2.5 in their study at which the role of PET/CT was investigated, and they found out the sensitivity of the technique 40% [12]. In our study, because there was ... [17]. The guideline also recommends PET for evaluation of therapy response and to make the decision of continuing the ongoing therapy or stopping and redirecting the patient to other salvage therapies. ... important limitation th at the number of patients is small especially in the first group, the number of studies intheliteratureinvestigatingtheroleofPETinthe diagnosis of distant metastasis preoperatively...
Ngày tải lên: 09/08/2014, 02:20
Formulation of businessstrategy for embroidered products of minh trang limited company in the period 2011 – 2015
Ngày tải lên: 26/03/2015, 10:59
The common errors in using some skinds of nouns in english made by the eleventh grade student at nguyen trai hight school, thai binh
Ngày tải lên: 16/07/2015, 08:06
Measurement of Color, Gloss, and Translucency of White Salted Noodles- Effects of Water Addition and Vacuum Mixing.pdf
... boiling time and the degree of starch swelling (Crosbie 1992). Accurate measurement of the color of boiled noodles necessitates the use of a method that minimizes the effect of variation on ... independent of noodle thickness. These were considerations in the development of methods in the present study. The aims of the study were to develop new and improved methods for measuring color, ... Tests in Experiment 1 The distance along the visual analogue scales (VAS) for each of the six samples was measured, the results of the 32 panelists were combined, and the mean scores were compared...
Ngày tải lên: 16/12/2012, 15:25
báo cáo hóa học:" En bloc excision and autogenous fibular reconstruction for aggressive giant cell tumor of distal radius: a report of 12 cases and review of literature" doc
... after excision of giant cell tumour of distal radius. J Hand Surg Br 1990, 15(4):496-500. 33. Gold AM: Use of a prosthesis for the distal portion of the radius following resection of a recurrent ... maintained all the records of the patients and followed them. All the authors read and approved the final manuscript Conflict of Interests The authors declare that they have no competing interests. Received: ... Santavirta S, Kiviluoto O, Koskinen EV: Application of free autogenous fibular graft in the treatment of aggressive bone tumours of the distal end of the radius. Arch Orthop Trauma Surg 1981, 98(4):285-7. 13....
Ngày tải lên: 20/06/2014, 04:20