... account [7] The aim of the present study was to 95 determine the impact of CYP3A5*1 and CYP3A5*3 genotype on the kinetics of tacrolimus in renal transplant recipients The drug dose and level, the drug ... Cadaver transplantation Age at the onset of the chronic renal deficiency (years) Age at the onset of the chronic renal deficiency for females (years) Age at the onset of the chronic renal deficiency ... pharmacokinetics are the drug transporters and the metabolizing enzymes [7,9] CYP3A, the primary subfamily of the cytochrome P450 (CYP) enzymatic system, is responsible for the metabolism of tacrolimus...
Ngày tải lên: 26/10/2012, 09:32
... (either at the time of the operation or during delivery) could introduce bias The hypothesized mechanisms by which cutting might affect long- term reproductive morbidity are shown in Figure The ... whether they had been circumcised, at what age, and about their attitude to the continuation of this practice Women with circumcised daughters were asked about the details of the operation for the ... details of the most recent FGC operation any daughter had undergone Eleven of these women were not aware that their daughter had gone to be circumcised until after the operation, and of these eight...
Ngày tải lên: 13/02/2014, 16:20
Tài liệu Is the long-term interest rate a policy victim, a policy variable or a policy lodestar? docx
... in key international currencies The long- term interest rate can then become a victim of the unintended consequences of such policies At the same time, the long- term rate has, during this crisis, ... operations to the point of saturation”: “My remedy in the event of the obstinate persistence of a slump would consist, therefore, in the purchase of securities by the central bank until the long- term ... Keynes regarded the long- term interest rate as a key policy variable Hence my question: is the long- term interest rate a policy victim, a policy variable or policy lodestar? Real long- term interest...
Ngày tải lên: 17/02/2014, 03:20
Tài liệu The long-term economic impact of higher capital levels docx
... focused on the steady-state impact at a point after the banks and the wider economy are assumed to have adjusted to the revised requirements (eg BCBS (2010)); others on the impact during the transition ... in the probability of crises, or about 55% of GDP Including other UK banks in the model is unlikely to affect the precision of our estimates materially, because the banks in our sample cover the ... capital requirements are independent of the capital ratio, whereas the incremental benefits decrease the higher the capital ratio We therefore present estimates of the costs and benefits for various...
Ngày tải lên: 20/02/2014, 19:20
The Long-Term Labor Market Consequences of Graduating doc
... and the other comparing these …ndings to an analysis of the 1990’ recession using the March CPS Section discusses the results in s relation to the theories outlined in section and concludes Theory ... for the national rate using the unemployment rate in the year an individual turned 22 and the state rate using the age 22 unemployment rate in the state if residence at age 14 (hereafter the ... attainment in the population (see for s example DeLong, Goldin, and Katz (2003)) Roughly speaking, the high group graduated at the beginning of the sample and the low group graduated at the end Thus...
Ngày tải lên: 17/03/2014, 03:20
Measuring the long-term perception of monetary policy and the term structure docx
... speci…cations for the long- term perception of the monetary authorities’in‡ ation target to explain, with the Fisher relationship, the presence of shifts in the long- term perception of the short -term interest ... second, the presence of some shifts in the short -term nominal endpoint stochastic process, or in other words, in the long- term perception of the level of the short -term interest rates In the appendix ... of the ECB The …rst component is intended to identify the long- term perception of monetary policy by private agents Here we use the long- term in‡ ation target perceived by the public from the...
Ngày tải lên: 22/03/2014, 23:20
Fiscal Dominance and the Long-Term Interest Rate: FINANCIAL MARKETS GROUP SPECIAL PAPER SERIES doc
... bonds The yield on government bonds will influence other risk exposures taken by the financial industry And it is long- term rates – not short -term rates – that help determine the prices of long- term ... developed the theoretical models of how central bank operations in long- term debt markets work He stressed the importance of the policies of government debt finance – not the central bank – on the long- term ... measure of the global fiscal position versus the non-Ricardian views of the private sector response Another is the nature of the policy responses (eg fiscal versus monetary dominance) and the interaction...
Ngày tải lên: 29/03/2014, 13:20
báo cáo hóa học:" The long-term benefit of computer-assisted surgical navigation in unicompartmental knee arthroplasty" doc
... unfavourably [25] At the time of the change the EIUS was relatively new without long- term registry data The latest National Joint Registry [9] reports higher revision rates for the EIUS (3.3 vs 1.8 ... the time of the operation was 59 years (range 41-78) in the navigated group and 61 years (range 44-71) in the non-navigated group There was no statistical difference in age between the two groups ... 19 agreements The disagreements were in the adjacent zones and may represent the effects of weightbearing The mechanical axis crossed the tibial plateau at a mean or 42.63% of the tibial width...
Ngày tải lên: 20/06/2014, 04:20
báo cáo hóa học:" The long-term benefit of computer-assisted surgical navigation in unicompartmental knee arthroplasty" pptx
... unfavourably [25] At the time of the change the EIUS was relatively new without long- term registry data The latest National Joint Registry [9] reports higher revision rates for the EIUS (3.3 vs 1.8 ... the time of the operation was 59 years (range 41-78) in the navigated group and 61 years (range 44-71) in the non-navigated group There was no statistical difference in age between the two groups ... 19 agreements The disagreements were in the adjacent zones and may represent the effects of weightbearing The mechanical axis crossed the tibial plateau at a mean or 42.63% of the tibial width...
Ngày tải lên: 20/06/2014, 07:20
Báo cáo sinh học: "The long term effects of chemotherapy on the central nervous system" docx
... are planned that further reduce the dose of craniospinal radiation to 1,800 cGy, virtually no attention has been paid to the possible contribution of the chemotherapy to the cognitive decline ... combination chemotherapy to the treatment regimens instead For example, attempts to reduce the dose of radiation to the brain and spinal cord from 3,600 centiGray (cGy) to 2,400 cGy led to the development ... of the most important of the risk factors are high dose and large volume radiation (craniospinal versus whole brain versus local) radiation The response of investigators has been to reduce the...
Ngày tải lên: 06/08/2014, 18:21
Báo cáo y học: "Closure of the NCBI SRA and implications for the long-term future of genomics data storage" doc
... finally being deleted RK: If there is a good chance that the data are going to be used by others, then yes, there is a good case for storing them Just storing the raw data for the sake of it, however, ... the long term it is probably better to just store the samples and then resequence them with improved technology MG: It’s extremely important that there is a proper archive to put things in The ... http://vamps.mbl.edu/) Other communities probably have their own databases MG: We’ve heard that the ENA will remain open We’ve also heard that the NCBI will continue to accept submissions from some of the large...
Ngày tải lên: 09/08/2014, 22:23
báo cáo khoa học: " The role of business in addressing the long-term implications of the current food crisis" docx
... implement the action plan of the Global Strategy on Diet and Physical Activity [14] The companies are gearing up to develop specific steps that will demonstrate their on the ground progress The Global ... range of ready-to-eat therapeutic foods The June 2008 High-Level Task Force of the United Nations on the Global Food Crisis that met in Rome included these elements in their Comprehensive Framework ... to the then heads of nutrition and agriculture at FAO that we undertake a joint piece of long- term work that aimed to consider what the agricultural supply should look like in a world of the...
Ngày tải lên: 11/08/2014, 14:21
Báo cáo y học: "The long-term prediction of return to work following serious accidental injuries: A follow up study" docx
... in these drop-outs Patients with a higher risk for longer sick-leave were, therefore, well represented in the final sample and the drop-outs probably did not affect the results substantially The ... information about the accidents were collected The patients rated their appraisal of the injury severity on a Likert scale ranging from “1 = very slight” to “5 = very severe” They also rated their ability ... scores The patients’ appraisals of the injury severity and of their coping abilities correlated with IES intrusion However, the two appraisals variables did not correlate with each other nor did they...
Ngày tải lên: 11/08/2014, 15:22
Báo cáo y học: " Change in quality of life and their predictors in the long-term follow-up after group cognitive behavioral therapy for social anxiety disorder: a prospective cohort study" pptx
... QoL at long- term Page of 10 follow-up; and 3) what predictors at baseline are associated with QoL in the long- term after group CBT We hypothesized that the improvement in QoL in the long- term after ... disorders conducted the treatment program, guided by a therapists’ manual During the treatment, the therapists had group discussions once a month to check on therapist adherence to the program and ... conducted in the analysis and we did not use any formal methods to correct this, given that the study is the first detailed, systematic evaluation of QoL domains in the long term and was therefore...
Ngày tải lên: 11/08/2014, 16:22
Báo cáo y học: "Recently published papers: small pieces of the puzzle and the long-term view" pps
... many of the issues identified by Angus and colleagues [3] and reinforces the need for longer term follow up and outcome variables in clinical studies of the critically ill Resuscitation At the opposite ... supported by previous work, as discussed in the accompanying editorial [8] The authors suggest that the key issue then becomes rapidly establishing the duration of ventricular fibrillation, in ... patients, whose response time was more than min, this intervention significantly improved the chances of the individual surviving to year (13/64 [20%] versus 2/55 [4%]) This goes against the dogma...
Ngày tải lên: 12/08/2014, 19:22
Báo cáo y học: " Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary" potx
... thus results in not only the short -term amelioration of the reward deficit but also suppression of the antireward system However, in the long term, there is worsening of the underlying neurochemical ... [1] It was termed the "brain reward cascade' (see Figure 1) The interactions of activities in the separate subsystems mentioned above merge together into the much larger global system These activities ... system [22] The ultimate result of the process is the activation of the meso-limbic dopamine pathway, which starts in the tegmental ventral area and ends at the dopamine D2 receptors on the cell...
Ngày tải lên: 13/08/2014, 16:21
releasing resources to support growth - the long-term benefits of finance transformation
... degree—and most of them have realized the gains they expected from their automation efforts • Over the last three years, companies have most often reallocated the resources they’ve saved through ... percent (123 responses) Cost control: 31 percent (56 responses) Analysis and comparison of the collective responses from each of these segments form the basis of this section of the report OCTOBER ... seeing the results they expected from these financial processing improvements projects, and how have they reallocated their financial resources? The results of this research study are persuasive The...
Ngày tải lên: 05/11/2014, 23:28
The long term effects of behavioral interventions on condom use and sexually transmitted infections among female brothel based sex workers in singapore, 1994 2002
... private homes of their pimps or agents Figure 2 Brothels in Singapore Front of a brothel The interior of a brothel Back alley of a brothel where clients gather A room in the brothel 18 Brothel-based ... to 100% to break the chain of transmission Otherwise, these sex workers may infect other clients who would in turn spread the infection to their wives Evaluation of the long- term behavioral intervention ... that the brothel owners send the sex workers regularly for their screening tests 19 The Anti-Vice Unit is also empowered to suspend sex workers from work in the brothels, deregister them from the...
Ngày tải lên: 17/09/2015, 17:20
The long term performance and survival patterns of canadian IPOs
... this thesis only focuses on long- term performance, we only review literature in long- term performance aspect rather than other aspects of IPOs such as underpricing, accounting performance, the ... reduced the performance difference between these two segments The results of IPO long- term performance are also found to be time sensitive both in terms of the IPO issuing year as well as the post-IPO ... significantly outperformed their matching firms in the first aftermarket year, and then neither outperformed nor underperformed the matching firms in the second and third aftermarket year Kooli et...
Ngày tải lên: 30/09/2015, 16:44
On the long term wireless network deployment strategies
... calculation, the authors concluded that the theoretical maximum throughput of a WLAN channel is sensitive to the packet size The author found that the higher the data rate , the more sensitive the packet ... while keeping the customer satisfied with the service The challenge is in the uncertainty of the future This thesis developed a decision analysis model to solve this problem This thesis also developed ... probabilistic model for the scenario in indeterminate future Figure 1-3 A projected traffic demand (versus time) at a given AP 1.4 Organization of the thesis This thesis uses the method of operational research...
Ngày tải lên: 27/11/2015, 11:26