... regulate the mitochondrial pathway of apoptosis [32,33] RANKL did not alter thelevelof Bcl-2 in rabbit osteoclasts but caused a marked increase inthelevelof Mcl-1, an anti-apoptotic member ofthe ... unprenylated form ofthe small GTPase Rap1A, thereby demonstrating that ALN inhibits protein prenylation in osteoclasts [2,22] Incubation of osteoclasts with 100 M ALN inthe presence of 100 ng/mL ... effect on thelevelof Bcl-2 protein (Figure 3d) However, RANKL alone consistently caused a threefold increase inthelevelof Mcl-1 protein in osteoclasts Treatment with ALN caused a decrease of approximately...
... Adh locus in populations from the types of micro-habitats It would also be interesting, however, to study the difference inthe genetic diversity ofthe kinds of populations Inthe case of laboratory ... exception Inthe case of D hydei populations, Table V shows the most basic data for compariThe examined parameters show thelevelof polymorphism to be higher in village populations for ofthe investigated ... populations originating from distilleries and 0.265 for those collected in villages On the basis ofthe results of a x test we concluded that all the populations at all the investigated loci were in Hardy-Weinberg...
... of rainfall At the end ofthe rainy season, due to the combination of floodwater draining from the upstream areas, the overland flood water entering from Cambodia across the Vietnam border, the ... forest inthe Upper and the Lower U Minh areas were burned, accounting for approximately 57% (17% inthe Lower U Minh and 40% inthe Upper U Minh) ofthe total Melaleuca forest area Inthe U Minh ... step inthe formulation of sustainable strategies in wetland conservation The inventories provide information on the type and the location of wetland, the economic and ecological value of the...
... were not there, other financial services providers might readily step in to take their place This article examines the role of community banks inthe U.S economyThe first section ofthe article ... understanding issues facing community banks I THE CURRENT ROLE OF COMMUNITY BANKS The banking system inthe United States has always been unique inthe sense of containing large numbers of small ... banks continue to be chartered (Chart 2) After declining steadily since the mid-1980s, the number of new bank charters inthe United States increased sharply during the second half ofthe 1990s,...
... Business Value of Information Technology inthe Internet Economy by Fang Yin, B.A Dissertation Presented to the Faculty ofthe Graduate School ofThe University of Texas at Austin in Partial ... dollars using the chain-type price indices for “Information processing equipment 22 and software” from the Bureau of Economic Analysis (BEA) Then the average ofthe beginning and ending values ... also included inthe regression The focus will be on the interaction term between the dummy and IT input Since the regressions are subject to collinearity problem due to the inclusion ofthe interaction...
... development ofthe game situation Inthe Figure 5, we have illustrated this inthe same way we did for the case of interruption The left hand side ofthe solid line is lower than that ofthe dotted ... interrupting the current utterance and switching to the new one For example, the left of Figure shows (solid line) the change ofthe importance score with time when an interruption takes place (the ... completely uttered The right part ofthe dotted line is lower than that ofthe solid, because the importance ofthe second utterance decreases over time when waiting interruption : with interruption...
... discipline involved in marriage and child-raising Inthe US, the number of births has fallen from 118 per 1000 women in 1960s to 66.7 in 2006, resulting in an increase inthe median age ofthe population ... productive, inthe face of diminishing resources Other examples of violence traceable to the globalization process have been the rise of dowry murder in India, the increase in trafficking and other forms ... through the revamping of a colonial ideology that blames the victims, relying on the increasing distancing of worlds, and the anxiety about others created by the apparent diminishing of resources...
... Similarly, the maximal effects of insulin on the state of tyrosinephosphorylation ofthe insulin receptor or of IRS1, or of phosphorylation of ERK1 ⁄ 2, was not significantly different in either group of ... involved in control of PKB, in response to insulin, which involves dual phosphorylation of PKB by insulin-activation ofthe phosphoinositide-dependent protein kinase-1 (PDK1) [28] and the yet ... molecular basis for insulin resistance Elevated serine ⁄ threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region ofthe insulin receptor and impairs their ability...
... businesses, the traditional target client group of savings banks By capturing and channelling more ofthe remittances into the financial system and intermediating the flow ofthe resources, savings ... disbursing of loans and collecting loan repayments Another promising track for savings banks is to invest their savings deposits in microfinance institutions by specialising 18 Microfinance Information ... analysis ofthe creditworthiness and the repayment capacity of their clients, a domain where they have a high levelof expertise, while savings banks could make use of their front and back of ce...
... number of microbes present inthe inoculum Afterwards, to examine the killing activity of Esc(1–18) against E coli and to determine whether this process was affected by the ionic strength ofthe incubation ... (p0), the peptide (0.1–2 lm) was injected into the subphase, and the increment in surface pressure ofthe LPS film upon intercalation ofthe peptide dissolved inthe subphase was monitored for the ... (Fig 10) The exposure of · 107 cellsÆmL)1 at the corresponding MIC of Esc(1–18) resulted in an irregular rod form with a deep wrinkling ofthe cell surface (within min) However, all of these changes...
... (2.15) Rather than using only the previous information, it is possible to obtain the probability oftheeconomy being in either recession or expansion Pr[St = j j using the full set of information ... level business cycle patterns In face, most ofthe time the state level business cycles of this group lay on the opposite side ofthe national business cycle.Most ofthe states fall into the fourth ... dispersion ofthe growth rates ofthe state housing index when the states economies are in recessionary phase ofthe business cycle This suggests that the housing market across states converges during...
... carriers ofthe virus, 60 million of them residing in Africa [1] Inthe Gambia, where HBV is endemic, the prevalence of chronic infection is 10– 15% ofthe adult population [2,3] Chronically infected ... survey conducted in three rural villages inThe Gambia An infant vaccination programme started in these villages in 1984 so the majority ofthe HBV carriers were over 20 years Levels of viral load ... was more noticeable inthe HBeAg positive group There was subsequent rebound of viral load at the withdrawal of LMV therapy Fluctuation oflevelof viral load was observed inthe untreated group...
... maximum and minimum values are defined through the observation ofthe world tendencies in terms of indicators for the long term, allowing periodic comparisons ofthe indexes obtained It is noteworthy ... smaller is the numerator and therefore the worse the situation of development Conversely, the closer the observed value is to the maximum value, the better the situation in terms of development The ... quality of life of stroke survivors in two cities differing in human development index ranking in Brazil Methods Sample The study included, initially, 77 people: 48 from the Metropolitan Region of...
... economyinthe coming years and decades, then we really need to start thinking about that well in advance The disintegration ofthe Soviet Union in 1991 demonstrated quite conclusively that there ... number of much dimmer lights These are the marginal participants inthe mass market—people who just meet the threshold for remaining inthe tunnel These people either hold the very lowest paying ... to enter the mass market As we have said, these are the growing middle classes of China, India and other nations The number of lights inthe tunnel is constantly growing As we watch the lights...
... lights inthe tunnel finally feel the impact and also begin to lose their light The owners ofthe businesses inthe tunnel are seeing much of their wealth gradually drain away The tunnel has become ... back in time to the year 1860 Inthe southern part ofthe United States, we knowwill find the greatest injustice ever perpetrated inthe history of our nation Here, long before the new light of ... inthe outcome ofthe war By the time the war ended in 1865, the Southern economy was in complete ruin One can speculate that if the blockade could have been maintained without an actual shooting...
... listed inthe table are already inthe process of being automated or offshored Others will be targeted inthe very near future Millions of other workers in occupations that not appear inthe list ... from the reality that the bulk ofthe job types in our economy have remained remarkably stable over time While technology has certainly impacted the way people in these jobs work, or the types of ... declining In recent years, one ofthe fewpositive stories inthe public health and nutrition arena has been the decline inthe smoking rate While the last graph was just an estimate, here is another...
... likely to eliminate many of these human interface jobs inthe coming years The Next “Killer App” Since the beginnings ofthe personal computer industry, computer hardware sales have often been driven ... and computers are advancing in capability and will increasingly invade the realm ofthe highly educated We’ll likely see evidence of this at some point inthe form of diminished opportunity and ... automated economy They hold firm to the belief that theeconomy will continuously generate jobs within the capabilities ofthe average worker—and that this process will continue indefinitely I think the...
... from exports, the major factor propping up the Chinese economy is the continuing enormous investment in infrastructure Clearly however, this levelof spending is not sustainable indefinitely Many ... point inthe distant future? To answer this question, let’s look at howmarkets work inthereal world The Predictive Nature of Markets One ofthe more interesting developments to arise out ofthe ... available @ Amazon THE LIGHTS INTHE TUNNEL / 114 saving Consumers inthe United States are expected to continue powering the factories in China and other developing nations even as the jobs from...