... support/attitudes of others Non-adherence with GFD compromised by: a Significant others having poor knowledgeof CD/GFD b Eating outside the home c Difficulties getting hold ofthe food, and when they do, the ... distance themselves from authority figures, including doctors (Booth, 1991) As such, they may eat gluten containing products to avoid the difficulties of others not understanding the importance ofthe ... University of Birmingham Research Archive e-theses repository This unpublished thesis/dissertation is copyright ofthe author and/or third parties The intellectual property rights ofthe author...
... Preparing the Western Cape for theKnowledge Economy ofthe 21st Century 3.1 The economy ofthe Western Cape is woven tightly into the global economy Almost two-thirds ofthe output ofthe private ... prepare the people ofthe province for theknowledge economy ofthe 21st century; To contain the spread of HIV/AIDS and TB; To empower the poor people of our province through the provision of basic ... prepare the people ofthe province for theknowledge economy ofthe 21st century; To contain the spread of HIV/AIDS and TB; To empower the poor people of our province through the provision of basic...
... professor and chair ofthe University of Southern California’s Department ofPsychology In 2006 he served as president ofthe Society ofClinicalPsychology (Division 12 of APA) and as chair of ... editor ofthe Journal of Family Psychology and is an associate editor ofthe Journal of Abnormal Psychology She is dedicated to the integration of science and practice in the field ofclinicalpsychology ... Professor ofPsychology and director oftheClinical Research Unit at the University of Houston, where he also teaches in the graduate clinical program He has served on the boards of major clinical...
... thus select and review studies based on what new knowledge they bring to our thinking about the theory of implementability The meaning and value of rigour will then be defined, examined, and ... operationalise the concept of guideline implementability To better understand the concept of implementability and the relationship between characteristics of guidelines and their uptake by physicians, the ... methodology Pioneered by Ray Pawson, the realist review is an explicitly theory-driven approach to the synthesis of evidence-it seeks to interrogate the theories that underpin the programs or interventions...
... months in the OFF arm Both regimens were tolerable, with the exception of higher neuropathy in the OFF arm The median OS in the OFF arm was 28 weeks, and that ofthe FF arm was 13 weeks, thereby ... for the first time that adjuvant systemic chemotherapy led to a superior survival as compared with the either the no-chemotherapy or the chemoradiotherapy groups Although the study methodology of ... improvement (4 months more than the treatment arm in CONKO-1) argues against the widespread use of this regimen Together, the CONKO-1 and the ESPAC-1 studies argue against the use of standard, post-operative,...
... in the control arm There were no differences in the rates of congestive heart failure between the two groups although there was a higher rate of asymptomatic decrease in cardiac function in the ... cisplatin arm vs the gemcitabine-only arm Based on these results, they initiated a phase III, multicenter trial ofthe two regimens for advanced biliary cancer (ABC-02) patients, the results of which ... after the results ofthe SHARP trial [29] There are no standard options after progression beyond first-line therapy with sorafenib Kaseb et al presented the results of a phase II study of erlotinib...
... planned cycles of chemotherapy The exploratory analysis of these results showed the patients with clinical stage II and T3N1 disease derived the greatest benefit from preoperative chemotherapy followed ... not determine the superiority of either neoadjuvant or adjuvant chemotherapy over each other It is recommended to wait for the results ofthe ongoing trials in Asia and Europe (ClinicalTrials.gov ... year tenance therapy The administration of pemetrexed in the maintenance setting was fairly well tolerated and was devoid of any cumulative toxicity in the subgroup analysis The rates of grade and...
... dysfunction ofthe Von Hippel Lindau tumor suppressor gene (VHL) in the majority of cases [5] The product ofthe VHL gene (pVHL) is a component of a ubiquitin ligase complex that mediates the cellular ... down-regulation, further supporting a role for these small molecules in the inhibition of angiogenesis Despite the fact that clinical trials establishing the activity of these agents in RCC represent ... the combined inhibition ofthe Ras pathway and of mTOR to overcome resistance to mTOR inhibitors alone Despite the discovery of these feedback and parallel pathways, their potential role in clinical...
... proteins involved in the human version ofthe reaction have an OP in the species, this may not be the case in reality because of diversification ofthe function ofthe OP or changes in the tissue or ... and 11 others These species were selected because ofthe completeness of their genome sequencing and annotation Together they represent more than 4,000 million years of evolution and span the major ... branches of life The inference process begins with the set of peer-reviewed curated human reactions in the pre-release database We project these curated reactions onto the genomes ofthe selected...
... attributes of workshops contribute to effects on professional practice [22] There is a specific lack ofknowledge on the impact ofknowledge transfer on complex clinical decision-making The majority of ... match new knowledge to theclinical context, and the activation of prior knowledge have been recognized as active components of PBL [56] Therefore PBL helps in the contextualization ofknowledge ... and in the application of knowledge, which are key components ofthe CIHR knowledge transfer model (listed as KT3 and KT5 by CIHR) The rationale for a PBL approach to knowledge transfer is based...
... president of two divisions ofthe American Psychological Association: the division ofthe history ofpsychology and the division of theoretical and philosophical psychology He is fellow ofthe American ... identify the boundaries ofthe subject and its central issues In wrestling with the problem of knowledge, the nature of good and evil, theories of governance, and the root question the sort of life ... precepts ofthe three “isms.” Describe the overall character of a psychology indebted to one of these to the exclusion ofthe others; Identify main currents in today’s psychology arising from each of...
... Williams had about views of this sort was the ambitiousness of their presupposed theory of error A theory of this kind is taking on the burden of explaining some ofthe divergence between ethical ... prospects for a theory of moral error I will set out each of these three kinds of counterargument in turn First, then, an important part ofthe argument for the absolute conception ofthe world is ... available in the ethical case There remains a viable distinction between the scientific and the ethical but this is not a demarcation ofknowledge from nonknowledge or ofthe world-guided from the merely...
... a number of factors, including the location ofthe service and its overall aims In principle ,the main activities ofthe service will be based around education and improving standards of sexual ... areas The number of sessions should be sufficient to ensure that the GPwSI is able to meet the competencies ofthe service requirements, the skill being assessed and the level of expertise required ... relevant clinical areas this is likely to be in the region of 40 – 50 clinical sessions or Personal development portfolio showing evidence of relevant clinical skills and knowledge and Evidence of...
... Development /The World Bank and its affiliated organizations, the Board of Executive Directors ofthe World Bank or the governments they represent The World Bank cannot guarantee the accuracy ofthe data ... in the secondary market activity, i.e the part ofthe virtual economy of online games that is managed by actors other than the game publishers Both ofthe two earlier methods of estimating the ... Potential ofthe Virtual Economy In the previous sections, the report introduced the main areas ofthe virtual economy and described the different business models that are used in them In each of the...
... oligonucleotides at 10 °C The CD spectra of oligonucleotides are influenced by both thebase composition ofthe nearest neighbor and the mutual arrangement of bases [28] The CD spectra of SREfos, SREGfos ... modulates the inducible conformational properties of SRE [23,24] The origin ofthe adequate conformational deformation ofthe CArG boxes lies in the polymorphism ofthe (A ⁄ T) domain Yet within the ... stabilization ofthe a1 helix of core-SRF Thus, both single and double mutations affect binding ofthe proximal core-SRF subunit to the first half-site ofthe CArG box As a matter of fact, the structure of...
... Carnovsky, one ofthe original actors ofthe Group Theatre, also aptly describes the ideal relationship ofthe SP coach and the SPs It is the coach’s vision ofthe patient case that enables the SPs ... see the theme I couldn’t see at the time the longing to express the inexpressible and the need to heal the emotional wounds that are part of being human So I sought the safety ofthe halls of ... dramatic arts, and the authenticity of our SPs’ performances in the service of training future generations of physicians The origins of drama and the art of acting are the subject of speculation among...
... harboring the common deletion By applying the specific probe, we can even detect the presence ofthe common deletion in the inner ear in the control group The proportions ofthe common deletion in the ... at the basal turn ofthe cochlea Inner hair cells were generally intact Figure shows typical images of hair cells ofthe organ of Corti from the high-dose d-Gal group They were taken from the ... account for the two copies ofthe b-actin gene in each cell nucleus The mtDNA copy number ofthe control group was taken as the reference point to calculate the relative mtDNA copy number ofthe experimental...
... for market-based approaches to better meet their needs, increase their productivity and incomes, and empower their entry into the formal economy The billion people at thebaseofthe economic ... the opportunities they represent Market-based approaches also warrant far more attention in the development community, for the potential benefits they offer in bringing more ofthe BOP into the ... majorities ofthe population in both regions are in the BOP But Africa shows the greatest disparity between the BOP share ofthe total population (95%) and the BOP share of health spending (54%) At the...
... energies ofthe original resiDG i;j due i in the native protein with the rest ofthe residues, self DDG k mutị are the changes ofthe self energies ofthe residues k that change either their ionization ... Electron-density map ofthe dCMP-binding region for the R188M CMP kinase variant The Fo ) Fc omit map calculated for the dCMPR188M CMP kinase complex in the absence ofthe dCMP model is green The contour ... Moreover, the kcat value with UMP increased by one order of magnitude with respect to the wild-type enzyme, at the expense ofthe Km value The overall effect of this structural change is a twofold...