the initial phase of drug dissolution and disintegration
Báo cáo y học: "Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock" potx
... samples of mL were collected without anticoagulant immediately before the infusion (0 hour) and 1, 1.5, 4.5, and or hours (depending on the frequency of administration of the β-lactam) thereafter; these ... contributions FJ and PFL conceived the study protocol FST, FJ, PFL, TD, XW, BL and HS participated in the design and coordination of the study ID and PW performed the PK analyses FST, PFL, DDB, JLV and FJ ... whether clinical or hemodynamic parameters could affect the PK profile of these drugs during such severe infections Administration of the four β-lactams was made according to local guidelines These...
- 9
- 327
- 0
ORAL CANCER AND ITS DETECTION - HISTORY-TAKING AND THE DIAGNOSTIC PHASE OF MANAGEMENT pdf
... Tobacco use The morbidities of smoking and 1,2 understanding the possible impact of a diminuuse of other tobacco products are well-known tion of serum levels of certain vitaBecause of this important ... exposure and the use of lip sunscreen and ment and the consumption of alcohol are protective coverings The dentist should emphastrongly linked, particularly when there is consize the strong risk of ... Surgeries and medications The dentist the history-gathering phase of treatment, the should determine whether the patient has any dental practitioner should be alert to the history of surgery,...
- 7
- 389
- 0
The National Study Report- Phase II of The National Study of Business Strategy and Workforce Development docx
... Ph.D., is Co-Director of the Center on Aging & Work/Workplace Flexibility He is also the Dean of the Graduate School of Arts and Sciences and a Professor in the Department of Psychology at Boston ... (45.7%) of the employees were women � One-third (30.2%) of the employees were members of a racial/ethnic minority group � 18.1% of the workforces were under the age of 24; � 37.7% were between the ... could affect their organizations? “In the United States and most other developed nations, the supply of 35-44 year-olds is shrinking And many of the best-trained people entering the workforce...
- 23
- 467
- 0
báo cáo hóa học: " Radioimmunotherapy consolidation and rituximab maintenance in the initial treatment of follicular lymphoma" potx
... chemotherapy and as maintenance [9] We now raise the question whether both rituximab and RIT should be used together as complementary methods to augment the results achievable with chemotherapy and ... omitted from the last two cycles of CHOP chemotherapy, to minimize blocking of CD20 antigenic sites prior to RIT If favorable results are achieved in this phase II trial, a phase III Page of randomized ... R-chemotherapy would be warranted List of abbreviations RIT: radioimmunotherapy; R-chemotherapy :rituximab and chemotherapy; RCHOP: combined rituximab, cyclophosphamide, doxorubicin, vincristine, and...
- 3
- 316
- 0
Báo cáo toán học: "Updown numbers and the initial monomials of the slope variety" ppsx
... xi ) ∈ C be the slope of ℓij Let A = C[mij ], and let In ⊂ A be the ideal of algebraic relations on the slopes mij that hold for all choices of the points pi Order the variables of A lexicographically ... by their subscripts: m12 < m13 < · · · < m1n < m23 < · · · Then [3, Theorem 4.3], with respect to graded lexicographic order on the monomials of A, the initial ideal of In is generated by the ... G-words and decreasing 012-trees (Theorem 7) and between R-words and decreasing 012-trees (Theorem 8) Our the electronic journal of combinatorics 16 (2009), #R82 constructions are of the same...
- 8
- 330
- 0
Báo cáo y học: "Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis" ppsx
... proteases and oxidative radicals that destroy the cartilage matrix The synovium itself is a rich source for the production of complement proteins and RF [17] On the other hand, RF can also protect the ... to the severity of the disease It is not yet clear, however, whether the induction of arthritis is due to the binding of citrullinated epitopes or cross-reactivity to other epitopes within the ... analysis of similar disease pathways operating during early, intermediate and late stages of the development of human arthritis, although they will not be identical to those of RA On the other hand,...
- 11
- 457
- 0
Báo cáo y học: "Impact of drug classes and treatment availability on the rate of antiretroviral treatment change in the TREAT Asia HIV Observational Database (TAHOD" pdf
... U01-AI069907, and the Ministry of Foreign Affairs of the government of The Netherlands The National Centre in HIV Epidemiology and Clinical Research is funded by The Australian Government Department of ... difficulties, drug interaction, adverse event and other Statistical analysis Rate of changing antiretroviral therapy was calculated as the number of events over the person-years follow-up The time ... cooperative network of clinicians throughout Asia and the Pacific that aims to expand the capacity for broader introduction of HIV/AIDS in the region TAHOD is the first collaborative study by the TREAT...
- 10
- 537
- 0
Báo cáo y học: "Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury" ppt
... change their pI values and affect their mobility in the IPGs Although the phosphorylated/oxidized form of Prx1/6 and the nitrated form of MnSOD in 2DE remain to be identified, the intensities of the ... indicating the involvement of Hsp27 in prolonged inflammation occurring in the late phase of SCI Nevertheless, the exact role of Hsp27 in SCI-induced neuropathogenesis remains to be explored On the other ... process, although the intensity of a protein spot in 2D gel was normalized by the sum of the intensity of all the spots present in each gel Second, it is known that there is the difficulty to...
- 16
- 429
- 0
Infelicities of the Intended Meaning of Canonical Texts and Norms Constraining Interpretation
... form reflect the rule -of- law value of the accessibility of law The norms that handle cases of failed law reflect both the rule -of- law value of accessibility and the more substantive value of consistent ... as to ban the cute and gentle panda?”) A and B did not clarify whether pandas were within the rule before voting The results of this disagreement are these The rule “no bears” admits of two relevant ... the rule they enact In other words, over the range of real or hypothetical applications of the rule, felicitous and infelicitous, if asked how the rule was intended to apply, each member of the...
- 24
- 441
- 0
Between fathers and fetuses - the social construction of male reproduction and the politics of fetal harm
... discussion of the rise of the concept of fetal rights and fetal protectionism can be found in Daniels, 1993.) After a brief discussion of the social construction of maternity and paternity, I analyse the ... Studies of male reproductive health and toxicity have Between fathers and fetuses concentrated primarily on the eVects of occupational and environmental exposures of men and less on the eVects of ... constituted by the analytically distinct and antithetical categories of male virility and vulnerability Men were assumed either to be invulnerable to harm from the toxicity of drugs, alcohol and environmental...
- 18
- 862
- 0
Tài liệu The Investing Secrets of Warren Buffett—and how to profit from them pptx
... case of let’s sit back and hope for the best Then there are others who deliberately not want to know anything about the activities of the company They want to study the “pure” movement of the ... features of the growth in sales and earnings: the rate of growth and the stability of the growth Conscious Investor provides proprietary tools to measure both of these for thousands of companies ... put the two charts together, we see how they track each other Sometimes the price moves ahead of the earnings per share and sometimes it is the other way around But over time they move together...
- 27
- 618
- 1
Tài liệu The General Theory of Employment, Interest, and Money docx
... MARGINAL EFFICIENCY OF CAPITAL 12 THE STATE OF LONG-TERM EXPECTATION 13 THE GENERAL THEORY OF THE RATE OF INTEREST 14 THE CLASSICAL THEORY OF THE RATE OF INTEREST o APPENDIX ON THE RATE OF INTEREST IN ... the demand for it, and that the rate of interest was, so to speak, the equilibrating price-factor determined by the point of intersection of the supply curve of savings and the demand curve of ... function of the rate of interest to preserve equilibrium, not between the demand and the supply of new capital goods, but between the demand and the supply of money, that is to say between the demand...
- 263
- 682
- 1
The general theory of employment interest and money (1936)
... call the user cost of the employment in question.[1] The excess of the value of the resulting output over the sum of its factor cost and its user cost is the profit or, it we shall call it, the ... fall to the appropriate level, which will occupy Book IV Thus the analysis of the Propensity to Consume, the definition of the Marginal Efficiency of Capital and the theory of the Rate of Interest ... return for their services, which from their point of view is their income, we will call the factor cost of A The sum of the factor cost F and the user cost U we shall call the prime cost of the output...
- 336
- 536
- 0
Tài liệu Báo cáo khoa học: Minor capsid proteins of mouse polyomavirus are inducers of apoptosis when produced individually but are only moderate contributors to cell death during the late phase of viral infection ppt
... levels of apoptotic markers during the late stages of MPyV infection However, comparison of the levels of apoptotic markers and cytotoxicity during the replication of wt MPyV, and replication of the ... as a control of sample loadings Discussion In the present work, the cytotoxic properties of the minor structural proteins (VP2 and VP3) of the MPyV were studied in the absence of other virus components ... in the late phase of the first lytic cycle Furthermore, we followed the apoptotic markers and cytotoxicity induced in 3T6 cells transfected with either the wt genome or the mutated MPyV genome Initially,...
- 14
- 539
- 0
Tài liệu SWIMMING IN SEWAGE: The Growing Problem of Sewage Pollution and How the Bush Administration Is Putting Our Health and Environment at Risk ppt
... be increasing, and there is evidence that the rate of infection is proportional to both the amount of time swimmers are exposed and the levels of pollution in the waters where they swim.60 According ... percent over land areas of the Northern Hemisphere during the 20th century,155 and global warming is predicted to further increase the intensity of rainfall events for parts of the United States.156 ... nearly twice the rate at Fall’s Creek (an average of 23 percent) On the basis of these findings, IKE urges the State of Indiana and/ or the City of Indianapolis to conduct a rigorous and comprehensive...
- 83
- 543
- 0
Tài liệu Báo cáo khoa học: Ionic strength and magnesium affect the specificity of Escherichia coli and human 8-oxoguanine-DNA glycosylases pdf
... affinity of Fpg for the THF:C ligand was 1.6-fold higher than for the THF:A ligand The presence of Mg2+ had little effect on the binding of Fpg to the THF:C ligand and slightly improved binding to the ... evaluate the effects of ionic strength and Mg2+ on the activity and specificity of OGG1, we measured the apparent values of k2 and k3 under conditions of low salt (KPi only) and no Mg2+, low salt and ... strength, the concentration of divalent cations such as Mg2+, the nature of the buffering agents, the presence of competing polyamines and other small molecules, and crowding by other macromolecules Their...
- 14
- 567
- 0
Tài liệu Báo cáo khoa học: Oxidized elafin and trappin poorly inhibit the elastolytic activity of neutrophil elastase and proteinase 3 pdf
... that the oxidant-promoted alteration of the Ki of elafin and trappin is caused by the oxidation of their P1¢ methionine residue Fig Mass spectra of native and oxidized elafin (A) and trappin (B) The ... correspond to a half-life of dissociation of 36–105 [15] The oxidation of elafin and trappin down-shifts the half-life of there complexes with NE to % 1.3– 1.8 On the other hand, the oxidized inhibitor–Pr3 ... binding of the methionine sulfoxide residue at the S1¢ subsite of the active centers of NE and Pr3 The fact that the S1¢ subsite of Pr3 is significantly smaller than that of NE [21] might then explain...
- 11
- 548
- 0
Tài liệu Báo cáo khoa học: "Enhanced word decomposition by calibrating the decision threshold of probabilistic models and using a model ensemble" pdf
... makes them either supervised or unsupervised algorithms The purpose of this paper is an analysis of the underlying probabilistic models and the types of errors committed by each one Furthermore, ... describe the process of word generation from the left to the right by alternately using two dice, the first for deciding whether to place a morpheme boundary in the current word position and the second ... nonboundaries in 0.9472 of the times correctly as TN and in 0.0528 of the times falsely as boundaries (FP) The algorithm correctly labels 0.3045 of the positions as boundaries (TP) and 0.6955 falsely...
- 9
- 557
- 0
Tài liệu The Strange Case of Dr. Jekyll and Mr. Hyde ppt
... nausea and distaste of life; and in the gloom of his spirits, he seemed to read a menace in the flickering of the firelight on the polished cabinets and the uneasy starting of the shadow on the roof ... away these random visitors or to repair their ravages Mr Enfield and the lawyer were on the other side of the by-street; but when they came abreast of the entry, the former lifted up his cane and ... middle of the pavement, and in spite of the biting weather, took off his hat and mopped his brow with a red pocket-handkerchief But for all the hurry of his cowing, these were not the dews of exertion...
- 96
- 594
- 0
Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25