... cellular processes such as replication and transcription To resolve such lesions the interstand crosslink repair pathway produces nicks in the strands on either side of the crosslinked bases essentially ... kinase assays The ~400bp substrates were purchased as double stranded “gBlocks” Gene Fragments from IDT The sense strand of these sequences is reported in Table The single stranded overhangs are ... using Sigma Plot 11.0 software using a Student s t- test The P
Ngày tải lên: 24/08/2014, 09:33
... Risk and Term Structure of Interest Rates • The risk structure of interest rates looks at bonds with the same term to maturity and different interest rates • The term structure of interest rates ... interest rates expected to occur over the n-period life of the bond Expectations Theory • Explains why the term structure of interest rates changes at different times • Explains why interest rates ... Expectations theory explains the first two facts but not the third Segmented markets theory explains fact three but not the first two Liquidity premium theory combines the two theories to explain...
Ngày tải lên: 05/01/2014, 16:56
the structure of central banking and the bank of canada
... Services As Canada s central bank, the Bank of Canada: • serves as the lender of last resort if a bank faces a liquidity crisis, thereby preventing bank runs and panics • has explicit responsibility ... pursuit of profit, the Bank of Canada is responsible for the country s monetary policy and for the regulation of Canada s deposit-based financial institutions Copyright 2011 15 - Origins of The ... Bank of Canada II Copyright 2011 15 - Formal Structure of the Bank of Canada I • Responsibility for the operation of the Bank rests with a Board of Directors, which consists of fifteen members:...
Ngày tải lên: 05/01/2014, 16:57
Tài liệu Gravitational Physics: Exploring the Structure of Space and Time pdf
... at a distance Other masses move along the straightest possible paths in this curved spacetime Einstein s theory thus expresses both the gravitational effect of mass and the response of mass to ... On the large scales of astrophysics and cosmology it is central to the understanding of some of the most exotic phenomena in the universe—black holes, pulsars, quasars, the final destiny of stars, ... its companion were neutron stars with precisely measured masses around 1.4 times the mass of the Sun The most exciting result of these studies was the recognition that the motion of the pulsar...
Ngày tải lên: 12/02/2014, 16:20
Tài liệu Inequalities in Higher Education and the Structure of the Labour Market pdf
... download from www.hsrcpress.ac.za Free download from www.hsrcpress.ac.za Free download from www.hsrcpress.ac.za Free download from www.hsrcpress.ac.za Free download from www.hsrcpress.ac.za Free download ... download from www.hsrcpress.ac.za Free download from www.hsrcpress.ac.za Free download from www.hsrcpress.ac.za Free download from www.hsrcpress.ac.za Free download from www.hsrcpress.ac.za Free download ... download from www.hsrcpress.ac.za Free download from www.hsrcpress.ac.za Free download from www.hsrcpress.ac.za Free download from www.hsrcpress.ac.za Free download from www.hsrcpress.ac.za Free download...
Ngày tải lên: 15/02/2014, 17:20
Tài liệu Báo cáo khoa học: Insights into the structure of plant a-type phospholipase D Susanne Stumpe, Stephan Konig and Renate Ulbrich-Hofmann ¨ ppt
... regions at the two ends of the molecule (Fig 3) An assignment of these relaxed structures to sequence regions of PLDa2 has not yet been possible According to the volume estimation on the basis of the ... a-helices is more intense [32], the spectrum suggests that b-sheet structures dominate This assumption was confirmed by the calculation of the a-helix and b-strand contents of the protein with the ... effects of salts according to the Hofmeister series, the chloride salt is less destabilizing than the acetate salt As discussed above, the inactivation by salts is connected with aggregation and...
Ngày tải lên: 19/02/2014, 02:20
Báo cáo khoa học: Flexibility and communication within the structure of the Mycobacterium smegmatis methionyl-tRNA synthetase Henrik Ingvarsson and Torsten Unge potx
... and the MSK lysine residue is not in contact with the adenylate phosphate The structures of the class aaRS enzymes show a small variation in structure of the KMSKS loop and that the loop is in ... Crystal structure of M smegmatis MetRS Fig The binding site of the KMSKS methionine (Met) residue The open conformation of the KMSKS loop exposes the binding site of the KMSKS loop Met residue in the ... positions the MSK Lys residue close to the catalytic site This is shown in the structural studies of E coli MetRS [25], Thermus thermophilus leucyl-tRNA synthetase [26] and Methanocaldococcus...
Ngày tải lên: 06/03/2014, 22:21
Báo cáo khoa học: The oxidative effect of bacterial lipopolysaccharide on native and cross-linked human hemoglobin as a function of the structure of the lipopolysaccharide A comparison of the effects of smooth and rough lipopolysaccharide ppt
... addition of the LPS Fig Comparison of the effects of the LPSs of rough S minnesota 595 (Re) and smooth S minnesota, in the absence and presence of EDTA, on the oxidation of a, a-cross-linked Hb The ... investigated by a comparison of the effects of rough and smooth LPSs of E coli, both in the presence and absence of EDTA (Fig 1) The rate of oxidation was increased in the presence of the LPSs of ... than the S minnesota LPSs in increasing the rate of oxidation, suggesting a difference in binding of the two types of LPSs The effect of the LPSs on the rate of oxidation of Hb A0 was much less...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo Y học: Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIa doc
... consists of an antiparallel packing of the two subunits and possesses C2 symmetry Tables and summarize the structural statistics of the ensemble of 24 structures, the lowest energy and the best ... kcalÆmol)1, comprising the 24 best RIIa D/D structures was used for further analysis (Fig 1) A superposition of the backbone of the final ensemble of 24 structures of RIIa D/D is shown in Fig The RIIa ... values of all ionizable residues of RIIa D/D The use of the ensemble of NMR structures is more suitable for the calculation because it provides us with a range of pKa values, from structures that...
Ngày tải lên: 08/03/2014, 22:20
Gravitational Physics Exploring the Structure of Space and Time docx
... at a distance Other masses move along the straightest possible paths in this curved spacetime Einstein s theory thus expresses both the gravitational effect of mass and the response of mass to ... On the large scales of astrophysics and cosmology it is central to the understanding of some of the most exotic phenomena in the universe—black holes, pulsars, quasars, the final destiny of stars, ... its companion were neutron stars with precisely measured masses around 1.4 times the mass of the Sun The most exciting result of these studies was the recognition that the motion of the pulsar...
Ngày tải lên: 14/03/2014, 10:20
Báo cáo khoa học: Relationship between the structure of guanidines and N-hydroxyguanidines, their binding to inducible nitric oxide synthase (iNOS) and their iNOS-catalysed oxidation to NO pptx
... [4–7] NOS-catalysed oxidation of some of these compounds showed kcat values as high as 80% that obtained with NOHA, and some proved to be selective for one of the three isoforms vs the others [5,7] ... pocket of NOSs [17– 20] Also, the fact that isoform-selective substrates for NOS [5,7,9] were characterized is striking, given the high level of similarity between the crystal structures of the ... to test these hypotheses Our results also suggest that the 3180 rational design of guanidines as new NO donors upon in situ oxidation by NOSs should take into account both thermodynamic and kinetic...
Ngày tải lên: 16/03/2014, 22:20
Báo cáo khoa học: "Parsing with Treebank Grammars: Empirical Bounds, Theoretical Models, and the Structure of the Penn Treebank" ppt
... illuminate the issues at hand Figures (a) and (b) show the traversal curves corresponding to the times in figure The interesting cause of the varying exponents comes from the “constant” terms in the theoretical ... where is the number of words in the sentence to be parsed, is the number of nonterminal categories in the grammar and is the number of (active) states in the FSA encoding of the grammar The time ... component is that passive saturation stays almost constant as span size increases However, the more interesting result is not that saturation is relatively constant (for spans beyond a small, grammar-dependent...
Ngày tải lên: 17/03/2014, 07:20
the role of morphology and crystallographic structure of metal oxides
... operations, used during the sensor s fabrication Thus, as the porosity and active surface area of the gassensing material increases, the sensor response increases as well (see Figs 38 and 39) This is ... parameters as well As a rule, the smaller the crystallite size is, the higher the sensor response But at the same time, the stability of gas sensors with finely dispersed grains is often decreased The ... contacts, the role of contact material is essential and should be considered in the design of gas sensors Moreover, it is possible to control the sensing properties of semiconductor gas sensors simply...
Ngày tải lên: 20/03/2014, 13:11
Governance and organizational structure of the inter-agency secretariat to the United Nations International Strategy for Disaster Risk Reduction (ISDR) pot
... its responsiveness to the requirements of programmes and legislative mandates, and monitor the effectiveness of the systems of internal control of the Organization” (General Assembly resolution ... relationships of the ISDR secretariat The existing SGB on the organizational structure of OCHA still indicates the long-since abolished secretariat of the IDNDR as a part of OCHA In the absence of the ... 37 The audit team reviewed the ISDR secretariat s existing organizational structure to assess whether the secretariat has the capacity and the structure to assure proper checks and balances and...
Ngày tải lên: 23/03/2014, 02:20
Báo cáo khoa học: "PCFGs, Topic Models, Adaptor Grammars and Learning Topical Collocations and the Structure of Proper Names" ppt
... labelled X and whose ith child is a member of TBi 1149 The set of trees generated by the CFG is TS , where S is the start symbol, and the set of strings generated by the CFG is the set of yields (i.e., ... consist of some subset of the six different collocation classes A0 through A6 in that order, while the second expansion says that a proper name can consist of some subset of the collocation classes ... (i.e., where B is a parent s label and β is the sequence of labels of its immediate children) there is a rule B → β ∈ R Formally, the sets TX are the smallest sets of trees that satisfy the following...
Ngày tải lên: 23/03/2014, 16:20
Chapter 2Communicating Over the Network Quangkien@gmail.com.OverviewDescribe the structure of a network, including the devices and media that are necessary for successful communications. Explain the function of protocols in network communications. Ex potx
... (IP) Assigns the appropriate source and destination addresses, Original source address of host Final destination address of host Used by routers in selecting the best path 35 Interaction of Protocols ... as: – The format or structure of the message – The process by which networking devices share information about pathways with other networks – How and when error and system messages are passed between ... networks Examples (4): Network Access Devices (Hubs, switches, and wireless access points) Internetworking Devices (routers) Communication Servers and Modems Security Devices (firewalls) 13 Intermediary...
Ngày tải lên: 01/04/2014, 12:20
Three essays on the credit growth and banking structure of Central and Eastern European countries
... Total Assets TCR Total Capital Ratio TSLS Two-Stage Least-Squares Estimator US United States of America ix Abstract This thesis is comprised of three essays on the credit growth and banking structure ... third essay in this thesis is Lessons from the EMU Countries This essay is provided in chapter 4, and it draws projections on the EMU membership of the CEE countries based on the experiences of the ... banking assets The analysis is based on an unbalanced panel of 16 years and 59 banks, comprised of 18 parent banks and their 41 CEE subsidiaries This study indicates that the size of the parent...
Ngày tải lên: 03/06/2014, 02:21
báo cáo hóa học:" The paediatric Bohler’s angle and crucial angle of Gissane: a case series" docx
... angle of Gissane 0-2 year age group comparisons was therefore defined as a p-value of less than 0.01, while for all other comparisons it was defined as a p-value of less than 0.05 For the statistically ... statistically significant (p = 0.004) Table illustrates the individual group results from our study Table displays the results of the statistical comparisons performed between the groups in our study ... variance to results seen in the other age groups and therefore multiple two-sample t-tests with Bonferroni adjustments were undertaken when analysing this result Statistical significance for the crucial...
Ngày tải lên: 20/06/2014, 04:20
báo cáo hóa học:" The paediatric Bohler’s angle and crucial angle of Gissane: a case series" pptx
... angle of Gissane 0-2 year age group comparisons was therefore defined as a p-value of less than 0.01, while for all other comparisons it was defined as a p-value of less than 0.05 For the statistically ... statistically significant (p = 0.004) Table illustrates the individual group results from our study Table displays the results of the statistical comparisons performed between the groups in our study ... variance to results seen in the other age groups and therefore multiple two-sample t-tests with Bonferroni adjustments were undertaken when analysing this result Statistical significance for the crucial...
Ngày tải lên: 20/06/2014, 07:20
báo cáo hóa học:" Assessment of the structure of the Hospital Anxiety and Depression Scale in musculoskeletal patients" pdf
... is of little use to clinicians wishing to use the HADS to quickly and simply screen their patients for elevated levels of anxiety and depression of the HADS Anxiety subscale scores The Depression ... assess the structure of the HADS in the rehabilitation context, and to evaluate its psychometric properties The aim of this study therefore was to assess the suitability of the HADS as a screening ... 'performs well in screening for the separate dimensions of anxiety and depression and caseness of anxiety disorders and depression in patients from nonpsychiatric hospital clinics' (p 75) The HADS...
Ngày tải lên: 20/06/2014, 15:20