the head and neck cancer alliance

... angiogenesis, immune and proinflammatory responses, and therapeutic resistance in head and neck squa- mous cell carcinoma (HNSCC) and other cancers [3-5]. How- ever, nuclear activation of hetero- and homodimers ... properly cited. NF-?B regulons involved in head and neck cancer& lt;p>Detailed analysis of NFkB regulons in 1,265 genes differentially expressed in head and neck cancer cell lines differing in p53 ... status, which is consistent with either the loss of the negative regulation (PTEN and PPAR), or the suppression of NF-κB and other signal pathways and genes by gaining or retaining

Ngày tải lên: 14/08/2014, 08:20

... IN THE HEAD AND NECK AT ENDOSCOPY LIN KAN 2012 MULTIMODAL OPTICAL SPECTROSCOPY AND IMAGING FOR IMPROVING CANCER DETECTION IN THE HEAD AND NECK AT ENDOSCOPY LIN KAN A THESIS SUBMITTED FOR THE ... importance over the last three decades [2] Fig 1.1 Long term trends in cancer incidence and death rates (1975-2006) [1] 1.1.1 Head and neck cancers 6 Head and neck cancers... diagnostic ... improving cancer diagnosis and characterization at endoscopy. We have developed an endoscope-based AF/DR spectroscopy and AF/WLR imaging system for cancer detection in the head and neck. The point-wise

Ngày tải lên: 09/09/2015, 10:09

... exploration into cytokines and mechanisms involved The current paper discusses decisions and methods behind exercise in head and neck cancer patients undergoing concomitant chemoradiotherapy Trial registration: ... carcinoma of the head and neck, scheduled for CCRT are randomized 1:1 to either a 12-week PRT program or control group, both with year follow-up Planned enrollment is 72 patients, and stratification ... ClinicalTrials.gov (NCT02557529) September 11th 2015 Keywords: Head and neck cancer, Head and neck squamous cell carcinoma, Chemoradiotherapy, Progressive resistance training, Exercise, Physical activity,

Ngày tải lên: 06/08/2020, 07:25

... swallowing interventions, and to explore any relationships between these strategies and intervention effects Randomised and quasi-randomised studies of head and neck cancer patients were included ... on understanding how and why interventions work in some situations and not others, rather than simply investigating whether they or not work [11] Sutcliffe and colleagues [12] argue the importance ... Normalcy of food intake in patients with head and neck cancer supported by combined dietary counseling and swallowing therapy: A randomised clinical trial Head Neck 2015 doi:10.1002/hed 35 Lazarus

Ngày tải lên: 20/09/2020, 01:02

... Figs 2, 3, and and in the context of the literature as outlined in the discussion the highest levels of DDR signalling due to CCRT and the highest levels of chromosomal fragmentation with the addition ... KLN, CMN and KJH were funded by Cancer Research UK Programme Grant A13407 AAK was funded by the Wellcome Trust MM and MP were funded by the Oracle Cancer Trust MD was funded by CRUK and The Rosetrees ... MACH-NC Collaborative Group Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients Radiother Oncol 2009; 92:4–14 Ang KK, Zhang Q, Rosenthal

Ngày tải lên: 20/09/2020, 01:18

... radiathion therapy in head and neck cancers: an update. Head and Neck 2007, 29:387-400. 3. Popovtzer A, Eisbruch A: Advances in radiation therapy of head and neck cancer. Expert Rev Anticancer Ther ... 54.45Gy the low dose, 69.96Gy and 66 Gy for the high dose in group A and B, respectively): the larger the dif- ference, the more pronounced the DVH tail to higher doses. Findings from the DVH ... modulated arc therapy in locally advanced head and neck cancers is feasible and effective, with acceptable toxicities. Introduction Radiotherapy (RT), with or without chemotherapy, is the primary

Ngày tải lên: 09/08/2014, 09:20

... Radiotherapy for Locally Recurrent Head- and- Neck Tumors. Int J Radiat Oncol Biol Phys . 14. Langlois D, Eschwege F, Kramar A, Richard JM: Reirradiation of the head and neck cancers. Radiother ... reirradiation alone or with che- motherapy. The likelihood of cure is impacted by the interval between the initial course of radiotherapy and reirradiation depending on, whether the carcinoma is a recurrence ... conception and design. HY drafted the manuscript, MO, KS, and KH criticized the manuscript. All authors read and approved the final manuscript. Competing interests The authors declare that they have

Ngày tải lên: 09/08/2014, 09:21

... with the use of helical tomotherapy Due to weight loss and tumor shrinkage especially in head and neck patients the parotid gland is expected to get higher doses than predicted Studies, whether these ... conventional 3DCRT in terms of parotid gland sparing The IMRT technique should therefore represent the standard of care for the treatment of head and neck tumors Parotid-gland-sparing up to mean doses of ... revised the manuscript and aided in the analysis DV participated in the coordination CG and TK conceived of the study, and participated in its design and coordination All authors have approved the

Ngày tải lên: 09/08/2014, 09:21

... Hospital, Amsterdam, The Netherlands, 3 Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands, 4 Department ... Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands and 5 Department of ORL, Academic Medical Center, Amsterdam, the Netherlands, Department of Head ... submandibular glands was removed in 53% of the cases, both submandibular glands in 12%, 6% had their superficial parotid gland removed another 6% had their superficial parotid gland and one submandibular

Ngày tải lên: 09/08/2014, 09:22

... weeks after completion of radiation therapy and then every 3 months thereafter for the first year, every 6 months for the second and third year, and then annually. The mean follow up time was 16.2 ... (IMRT) and concurrent chemotherapy. Methods and materials: Thirty-nine patients with squamous cancer of the head and neck were treated by definitive concurrent chemotherapy and IMRT to a median dose ... Calais G: Final results of the 94-01 French Head and Neck Oncology and Radiotherapy Group randomized trial comparing radiotherapy alone with con- comitant radiochemotherapy in advanced-stage oropharynx

Ngày tải lên: 09/08/2014, 10:20

... radiotherapy with or without chemotherapy in advanced head and neck cancer Experience from four nonrandomized... therapy in head and neck cancers: dosimetric advantages and ... and neck cancer: preliminary results Head. .. therapy) boost: a new accelerated fractionation schedule for the treatment of head and neck cancer with intensity modulated radiotherapy ... in advanced head and neck. .. Selection and delineation of lymph node target volumes in head and neck conformal radiotherapy Proposal for standardizing terminology and procedure

Ngày tải lên: 09/08/2014, 10:20

... association of MMPs and TIMPs and the possible therapeutic aspects of these proteinases in potentially malignant and malignant head and neck lesions. So far, no promising drug target therapy has been ... the head and neck is a multi-step process. Head and neck malignancies consist of a heterogeneous group of neoplasia. They constitute the sixth most common malignancy, and more than 90% of these ... to their ability to degrade the ECM and basement membranes [24]. Regulation of MMPs in potentially malignant and malignant head and neck lesions The MMPs are regulated at many levels [21]. The

Ngày tải lên: 10/08/2014, 05:21

... In Squamous Cell Carcinoma Of the Head And Neck as a Target for a Novel Nanotherapeutic Drug Head And Neck- Journal for the Sciences And Specialties Of the Head And Neck 2009; 31: 475-81 113 Wang ... smoking in never drinkers, and the risk of head and neck cancer: Pooled analysis in the international head and neck cancer epidemiology consortium Journal Of the National Cancer Institute 2007; 99: ... Nanoparticles, targeted therapeutics, head- and- neck cancer, RNA interference, drug delivery, radiosensitization, photothermal therapy Introduction Head- and- neck cancer is the sixth most common cancer worldwide,

Ngày tải lên: 15/01/2020, 16:59

... dental and medical practitioners, should be aware of the presenting features of head and neck cancer, and the local referral pathways for suspected cancers. 2.5 SCREENING FOR HEAD AND NECK CANCER ... 12 DIAGNOSIS AND MANAGEMENT OF HEAD AND NECK CANCER 3 3 5 Overview of treatment of the primary tumour and neck Thissectionaddresses the rstlinetreatmentof head and neck cancer. Managementofrecurrent tumour ... PRESENTATION, SCREENING AND RISK FACTORS 24 DIAGNOSIS AND MANAGEMENT OF HEAD AND NECK CANCER 1 ++ 2 ++ 1 ++ 1 ++ 1 ++ For patients with advanced head and neck cancer, where postoperative radiotherapy is...

Ngày tải lên: 14/02/2014, 22:20

... in the gut of the sandfly, but the organism completes its life cycle in the host following the fly bite. The sandfly inoculates the host with the organisms in the promastigote stage. Once the ... manifestations in the head and neck. HSV-1 and HSV-2 Infection with HSVs may result in significant head and neck manifestations. The severity seems to depend on the immune state of the infected person. ... and Infectious Disease / HEAD AND NECK INFECTIONS Infectious Diseases of the Head and Neck A Review Kathleen T. Montone, MD Key Words: Infectious diseases; Head and neck; Bacteria; Fungus; Protozoa;...

Ngày tải lên: 19/02/2014, 08:20

... guide to neck dissection classification and TNM staging of head and neck cancer / Committee for Neck Dissection Classification, American Head and Neck Society [and] Committee for Head and Neck Surgery ... guide to neck dissection classification and TNM staging of head and neck cancer. — 3rd ed. / Committee for Head and Neck Surgery and Oncol- ogy, American Academy of Otolaryngology Head and Neck Surgery ... vestibule and the vermillion borders of the lips and continues to the junction of the cricoid cartilage and the cervical trachea and at the level of the cricoid where the hypopharynx meets the cervical...

Ngày tải lên: 15/03/2014, 00:20

... summary of the main recommendations in the SIGN guideline on the Diagnosis and management of head and neck cancer. Recommendations are graded A B C D to indicate the strength of the supporting ... practitioners, including dental and medical practitioners, should be aware of the presenting features of head and neck cancer, and the local referral pathways for suspected cancers.  Dental practitioners ... criteria. B Fine needle aspiration cytology should be used in the investigation of head and neck masses. D The risk of having head and neck cancer can be reduced by:  not smoking or chewing tobacco ...

Ngày tải lên: 15/03/2014, 01:20