the genetic basis of allergic disease pdf
báo cáo khoa học: " Genetic mapping of wild introgressions into cultivated peanut: a way toward enlarging the genetic basis of a recent allotetraploid" docx
... background of the cultivated variety provided a set of lines offering an optimal distribution of the wild introgressions Conclusion: The genetic map developed, allowed the synteny analysis of the A ... introgression of a small fraction of the wild genome species while keeping the genetic background of the cultivated is a good mean to explore the largely untapped reservoir of useful alleles of interest ... development and the analysis of the genome-wide segment introgressions of the most probable wild progenitors of the cultivated peanut species (A duranensis and A ipaënsis) into the background of the cultivated...
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Elucidating the genetic basis of severe obesity learning from the experiments of nature
... ELUCIDATING THE GENETIC BASIS OF SEVERE OBESITY: LEARNING FROM THE EXPERIMENTS OF NATURE DR LEE YUNG SENG MBBS, MMED (PAED MED), MRCP (UK), MRCPCH, FAMS A THESIS SUBMITTED FOR THE DEGREE OF PH.D ... on the AGRP/NPY neurons in the arcuate nucleus The Elusive Satiety Factor The regulation of energy balance has been the focus of discussion dating back to 1783, and the quest to understand the ... 1995) This led to the hypothesis of resistance to the action of leptin in these individuals, so that the increase in adipose tissue mass is maintained As the vast majority of obese individuals...
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The genetic basis of type 2 diabetes in a multi ethnic population in singapore
... likely the cause of familial aggregation of diseases 7.3 THE COMPLEXITY OF THE GENETICS OF TYPE DIABETES Genetic studies of diseases have traditionally relied on two methods to discover the responsible ... examined In this thesis, we begin by examining the impact of a family history of diabetes; to further assess the genetic basis of type diabetes, we next examine the contribution of recently identified ... to determine the effect of a positive family history on the risk of developing T2DM Furthermore, these studies were unable to determine the impact of family history of T2DM on other diabetes...
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THE MOLECULAR BASIS OF PLANT GENETIC DIVERSITY pdf
... for the detection, characterization, and evaluation of genetic diversity in plant populations These techniques can be chosen on the basis of how they display genetic differences, the type of data ... into the dynamic process of genetic variation by presenting the thoughts of some of the scientists who are engaged in the development of new tools and ideas used to reveal genetic variation, often ... by the markers rather than describing the genetic diversity of the organism Although the results correlate with genetic diversity, the indices often have no biological meaning in a population genetic...
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Tài liệu Health and Safety in the Child Care Setting: Prevention of Infectious Disease pdf
... of Infectious Disease We have added a short time-slot at the end of each unit for the instructor to ask the class how and when they would communicate the concepts learned to the families of the ... in their child care setting that increase the risk of disease • Ask providers to describe the procedure that will reduce the spread of illnesses in the child care setting • Ask the class when they ... one method of control in order to reduce the transmission of infectious disease You can control the spread of communicable disease in three ways: Attack the source of infection or the “first...
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Molecular Basis of Pulmonary Disease Insights from Rare Lung Disorders pdf
... The pathology of vascular remodeling is described, including the potential sequence of events, cell types, and processes involved The genetics of the disease together with the identification of ... the same degree of efficacy with the fewest number of subjects exposed to the more toxic therapy There are a number of alternative study designs that can be considered in the context of rare diseases ... underscored the importance of the integrity of the alveolar epithelium in the pathogenesis of parenchymal fibrosis Opportunities to approach lung disease pathogenesis from the vantage point of a primary...
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GENOMIC DISORDERS The Genomic Basis of Disease doc
... or required further explanation of the need for their samples I often thought of the irony of the situation At these reunion parties, Dr Garcia would oversee the administration of the electrical ... (3) elucidation of the chemical basis of heredity, the molecular basis of disease has been addressed in the context of how mutations affect the structure, function, or regulation of a gene or its ... with the arrowheads representing the short, direct repeats formed at the point of insertion The left half of Alu contains the A and B boxes of the RNA polymerase III promoter The two halves of the...
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Báo cáo khoa học: "Predicting Strong Associations on the Basis of Corpus Data" pdf
... as the cosine of the angle be- the magnitude of asymmetry In a similar vein, Wettler et al (2005) successfully predict associations on the basis of co-occurrence in text, in the framework of ... ensembles taking the (harmonic) mean of the natural logarithm of the ranks, since we found these to perform better than those working with the original ranks.2 Table compares the results of the most ... will study only the first two of these approaches, as the different metrics of our models cannot simply be combined In the case of the harmonic mean, we actually take the logarithm of rank+1, in...
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báo cáo hóa học: " Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease" pdf
... sensitivity to the pro-inflammatory effects of DE Subchronic DE Exposure Modifies the Pro-inflammatory Profile of the Midbrain In an effort to further address the degree of sensitivity of the midbrain ... animals While all components of the brain, with the exception of the cerebellum, showed an elevated TNFa response to DE at some concentration of DE, the midbrain was the most sensitive, producing ... regions: the olfactory bulb, the frontal lobe, the temporal lobe, the midbrain, and the cerebellum were assessed for levels of pro-inflammatory cytokines/chemokines and markers of neurodegenerative disease...
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báo cáo hóa học:" Genetic lesions within the 3a gene of SARS-CoV" pdf
... that these two transmembrane domains are essential for the expression of 3a on the cell surface It is possible that the aberrant nature of the oligo(T) tract in the 3a gene is akin to that of the ... are the source of these nucleotide aberrations (data not shown), and these results showed that different variants of the 3a gene exist in the viruses that were replicating in these patients The ... at least one of these truncated forms of 3a, named as 3amut1, can be detected in the lysate of infected cells [6] It has been shown that the 3a is localized to the cell surface of SARS-CoV infected...
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Báo cáo sinh học: "The complex genetic basis of simple behavio" ppt
... determining whether specific genes are directly involved in the trait, in quantifying the magnitude of their effect, and in evaluating whether these genes also contribute to other traits The effect of a ... neurobehavioral diseases mainly reflect the effects of large numbers of genetic variants of relatively small effect and, therefore, that genetic dissection of such traits will require investigation of samples ... important form of corroboration of the role of a given gene in contributing to complex behavioral traits Demonstrations of the importance of pleiotropy in the genetic regulation of behavioral...
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Báo cáo sinh học: "Deciphering the genetic code of morphogenesis using functional genomics" pdf
... to the earlier blastoderm stages To validate their experimental approach, the authors compared their gene list with the approximately 2,000 genes found to be expressed in the early embryo in other ... that 12 out of 15 of these genes are expressed in a spatially restricted pattern in regions undergoing distinct morphogenetic processes This series of studies led to the identification of a novel ... identify genes downstream of cell fate Given the extensive information from genetic studies about the transcriptional regulators that direct the early morphogenetic events of embryogenesis, it is...
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Báo cáo y học: "Nature of Regulatory T Cells in the Context of Allergic Disease." ppsx
... T Cells in the Context of Allergic Disease The mechanisms by which SIT has its effects include the very early desensitization effect The regulation of Tcell responses by generation of T regulatory ... suppression of basophil IL-4 and IL-13 during early phases of rush immunotherapy has been demonstrated.20,21 SIT modifies the number and the function of effector cells that mediate the allergic ... the seasonal increases in the number of basophils and eosinophils25,26 in the mucosa, as well as the number of mast cells in the skin27 and the IgE-mediated release of histamine by basophils.3,28...
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Báo cáo y học: "Introducing Arthritis Research & Therapy’s 10th anniversary issue, ‘The Scientific Basis of Rheumatology: A Decade of Progress’" pdf
... evidence for the immunological and nonimmunological basis of disease and the implications for future treatment options The Scientific Basis of Rheumatology: A Decade of Progress should provide the reader ... molecular-based therapy Szekanecz and Koch [4] review the crucial involvement of the vasculature in inflammatory rheumatic diseases, including the role of the vasculature in atherosclerosis and ... transplantation in autoimmune diseases are the subjects of the article by Hügle and van Laar [5] They review the available evidence of this intensive therapy – traditionally, a salvage therapy for nonresponders...
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RESEARCH ON THE GENETIC DIVERSITY OF SOME SOYBEAN VARIETIES THAT ARE RESISTANT TO RUST DISEASE IN DIFFERENT WAYS
... damage in the yield of soybeans in many countries Signs and symptoms of disease: Signs of the disease are the dots in the leaf blade about mm, growing gradually to turn yellow and then brown, the size ... SSR, the study analyzed genetic relationship of 50 kinds of soybean, the results showed that the polymorphism of SSR is at higher level - With the method of 2-dimensional electrophoresis, the ... with complementary sequences with the sequence of the samples The RAPD markers used in the study of diversity and genetic mapping of the typical locus include the following: (i) designing sample,...
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Tài liệu The Illustrated Dictionary of Electronics P2 pdf
... alpha decay The decay of a substance in which the nuclei of the atoms emit alpha particles, resulting in a change of the atomic number and atomic weight of the substance over a period of time alphanumeric ... start of the trace on the indicator screen to eliminate the altitude circle in the display ALU Abbreviation of ARITHMETIC AND LOGIC UNIT alumel An alloy used in the construction of one type of THERMOCOUPLE ... determination of current of large dimension, or of the size of the ampere ampere-hour Abbreviations: Ah, amp-hr The quantity of electricity that passes through a circuit in one hour when the rate of flow...
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Tài liệu The Illustrated Dictionary of Electronics P1 pdf
... energy, on account of the motion of the source and/or the detecting apparatus A small displacement in the apparent positions of the stars from month to month on account of the earth’s orbital ... execution of a specific operation absolute magnitude For a complex number quantity, the vector sum of the real and imaginary components (i.e., the square root of the sum of the squares of those ... measurement of current Measurement of a current directly in terms of defining quantities TANGENT GALVANOMETER method: Current is proportional to the tangent of the angle of deflection of the needle of...
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