the generalized care of the patient with acute lymphoblastic leukemia

... most of the studies The standard of supportive care for AML has changed dramatically over the decade The toxicity data from this analysis may therefore overestimate the adverse events of the regimens ... studies involving 397 patients, of whom 144 (36.2%) were induced twice with CAG Of the patients who received one cycle, 46.60% (185/397) went into CR, another 8.31% (33/397) of the patients achieved ... did not specify AML status of the rest 117 patients These 117 patients were therefore excluded for this comparison (Table 3) The heterogeneity test of CR event rates of these studies revealed Q...

Ngày tải lên: 10/08/2014, 21:23

... by the Kaplan-Meier method using the SPSS 13.0 software Results Characteristics of the patients Characteristics of the patients at the time of diagnosis are listed in Table The median age of these ... study, the response results of HA are comparable with these and other reported results in elderly patients with AML [15-21] The response rates of HA are also comparable with the data of elderly patients ... while the ED rate within the first month of induction therapy in patients JW designed the research, supervised the research, analyzed the data, wrote and revised the paper SL analyzed the data...

Ngày tải lên: 10/08/2014, 22:20

... mtDNA content The lines connect the medians, the boxes cover the 25th to 75th percentiles, and the minimal and maximal values are shown by the ends of the bars Patients with lower amount of CD ratio ... amplification plot for the lymphocyte samples The level of the common mitochondrial deletion in the lymphocyte samples is within the linear range of the standard curve Figure Relative change of mtDNA content ... signed an informed consent to the use of blood samples in accordance with the Declaration of Helsinki and with the approval from our Institutional Review Board The amount of CD in skeletal muscle...

Ngày tải lên: 09/08/2014, 09:21

... to the loss of the overlying retina If the edge of the dialysis remains close to the RPE, then the tear may not be discovered unless scleral depression is performed As the vitreous contracts, the ... asymptomatic (i.e., the person often is unaware of the loss of an area of peripheral vision) The sudden onset of numerous floaters and the occurrence of flashes of light are hallmarks of a potential retinal ... greater the possible loss of vision after reattachment of the retina The prognosis is very poor when the detachment involves the macula The longer the macula is detached, the poorer the resultant...

Ngày tải lên: 22/03/2014, 09:20

... isolated from the serum samples of the patients with acute coronary syndrome Furthermore, using combination of bacteriological and PCR-based methods we show herein that patients with acute coronary ... All patients were informed about the purpose of the study and have given written consent regarding participation in the study Initial observation has been done on the group of 18 patients with acute ... specificity of the primers and probe Real-time PCR was performed with the iCycler IQ ystem (Biorad, USA) µl of extracted DNA was analyzed with the PCR mixture in a total volume of 25 µl The PCR 184...

Ngày tải lên: 26/10/2012, 08:57

... 2-D pattern of the silver stained gel image of the master gel image 2-D pattern of the silver stained gel image of the master gel image 2-D pattern of the silver stained gel image of a master ... + Annexin Patient A 129 76 77 67 #02-05p 129 76 77 67 #02-02b Figure Detail of the two-dimensional patterns of patient A Detail of the two-dimensional patterns of patient A Detail of the two-dimensional ... Figure 3the two-dimensional patterns with different expression of the Ku antigen Detail of Detail of the two-dimensional patterns with different expression of the Ku antigen Selective deficiency of...

Ngày tải lên: 18/06/2014, 15:20

... well as of Vλ1C–Jλ3 rearrangements in both the peripheral blood and parotid gland of this patient with SS One feature of the present patient was that the κ/λ ratio of B cells in the patient s ... rearrangements of B cells from the peripheral blood compared with the parotid gland of a patient with SS or with normal donors § P < 0.001, significant difference between the mutational frequency of the ... detected in the salivary glands of patients with SS [3,6], but it is not known whether the microenvironment of these cell clusters is sufficient for the induction of a germinal center response Of note,...

Ngày tải lên: 09/08/2014, 03:24

... Therapy Vol 11 No Kappen et al in colonic tissue of a BD patient, IFN-γ, TNF-α, and IL-17A appear to be key cytokines, even in a treated patient Competing interests The authors declare that they ... Schmidt CA, Macintyre EA, van Dongen JJ, Langerak AW: Different chromosomal breakpoints impact the level of LMO2 expression in T-ALL Blood 2007, 110:388-392 Yazici H, Fresko I, Yurdakul S: Behçet’s ... Baeten D: Distinct synovial immunopathology in Behçet disease and psoriatic arthritis Arthritis Res Ther 2009, 11:R17 Dik WA, Nadel B, Przybylski GK, Asnafi V, Grabarczyk P, Navarro JM, Verhaaf B,...

Ngày tải lên: 09/08/2014, 14:22

... (BCL2L1) for The relative amounts of the genes of interest and the b2M reference gene were measured in two independent assays The 2(-ΔΔCT) method was used to present the data of the genes of interest ... article as: Huang et al.: Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia Journal of Hematology & Oncology 2010 3:44 ... family genes of the mitochondrial pathway, and the TRAIL (TNFSF10) gene of the death receptor signaling pathway [22], furthermore, in our previous study, the genes (SPP1 and CREBBP) of the TGF-b...

Ngày tải lên: 10/08/2014, 22:21

... or the barrier effects of perfluorodecaline may cause the loss of cell density and morphological changes For these reasons, we decided to remove the perfluorodecaline without any delay In the ... Giant retinal tear with shallow detached retina involving the macula in the right eye (c) Reattachment of retina after vitrectomy sis, but could not obtain these results as the patient refused (4) ... Concent Written consent of the patient was obtained for publication of this case report Figure 17-year-old male with an residue in anterior chamber of Coloura images of perfluorodecalinintact...

Ngày tải lên: 11/08/2014, 10:23

... examination of the specimens BYJ assisted in the manipulation of the specimen and critically revised the manuscript JK contributed to the operation of our patient and to the critical review of the manuscript ... plate on the bronchial wall The bronchial cartilage is primarily responsible for maintaining the stability of the airways Metaplastic ossification happens as part of the aging process of the thyroid ... infiltration of inflammatory cells within the cavity wall The bronchial epithelium is severely desquamated with some intact remaining regions (right rectangle) (B) An enlarged photograph of right...

Ngày tải lên: 11/08/2014, 12:20

... g/ m2 in CLL patients Both the weak expression of CD20 and the extremely elevated tumor burden of CLL patients (and certainly of the patient in this case) might explain the need for the higher ... and the risks of any further aggressive chemotherapy in a severely pancytopenic patient, rituximab monotherapy was started with a weekly dose of 375 mg/m2 After a hospitalization of 35 days, the ... rituximab therapy was given at an increased dosage of 600 mg/m2 weekly × 5, then 600 mg/m2biweekly × without any other cytotoxic drugs During this therapy of intensified rituximab, the patient...

Ngày tải lên: 11/08/2014, 21:22

... and the low density area may not be apparent Some early signs of acute MCA infarction are loss of definition of the grey/white interface in the lateral margins of the insula, leading to loss of ... accident The Royal College of Radiologists guidelines now suggest that such scans should be performed within the initial 24 hours of presentation The CT scanning of such patients is performed without ... be seen within the choroid plexus and occasionally within the basal ganglia Acute haemorrhage appears as an area of high density (white) There is often surrounding low density oedema with associated...

Ngày tải lên: 11/08/2014, 23:21

... evidence of the validity of PANSS-EC One of the most interesting findings of the validation process of the PANSS-EC subscale has been the quantification of the reductions on the scoring system of the ... structure of the PANSS-EC subscale with the five suggested items The variance, explained as the matrix of components, confirms the robustness of the separated use of the excitement component of the ... to validate the PANSS-EC in patients with acute psychosis and agitation through the comparison of PANSS-EC ratings with ratings of the Clinical Global Impression of Severity (CGI-S), the Clinical...

Ngày tải lên: 12/08/2014, 01:22

... (specifically the change in the ratio between the partial pressure of oxygen and the fraction of inspired oxygen (PaO2:FiO2 ratio)), the number of ventilation-free days, and the mean duration of ventilation ... patients with direct lung injury In a recent study of pediatric patients with acute lung injury, treatment with surfactant significantly improved oxygenation and survival in the subgroup of patients ... ratio), the number of ventilation-free days, and the mean duration of ventilation Unfortu- Page of Characteristics of the trials eligible for meta-analysis Article (Jadad score) Design Number of patients...

Ngày tải lên: 12/08/2014, 23:22

... pothesis have attempted to include these theories [5-8] The theory of Greaves and that of Kinlen have been discussed in one of the chapters in this book One of the limitations of the theory of ... has the goal of introducing the reader into the principal advances in the molecular biology of acute lymphoblastic leukemia (ALL) with application to the clinic There are four sections in the ... infections and risk of acute lymphoblastic leukemia in the offspring American journal of epidemiology 2003;158(3) 207-213 Infectious Etiology of Childhood Acute Lymphoblastic Leukemia, Hypotheses and...

Ngày tải lên: 17/03/2014, 12:20

... differential diagnosis (Table 52-4) For instance, the finding of scaling papules (present in patients with psoriasis or atopic dermatitis) places the patient in a different diagnostic category than ... skin lesions If the examiner focuses on linear erosions overlying an area of erythema and scaling, he or she may incorrectly assume that the erosion is the primary lesion and the redness and ... raised above the surface of the surrounding skin and hence palpable (e.g., a closed comedone, or whitehead, in acne) Nodule: A larger (0.5–5.0 cm), firm lesion raised above the surface of the surrounding...

Ngày tải lên: 06/07/2014, 20:20

... Erosion: Loss of epidermis without an associated loss of dermis Ulcer: Loss of epidermis and at least a portion of the underlying dermis Excoriation: Linear, angular ... Atrophy: An acquired loss of substance In the skin, this may appear as a depression with intact epidermis (i.e., loss of dermal or subcutaneous tissue) or as sites of shiny, delicate, wrinkled ... configuration of skin lesions formed from coalescing rings or incomplete rings Pruritus: A sensation that elicits the desire to scratch Pruritus is often the predominant symptom of inflammatory...

Ngày tải lên: 06/07/2014, 20:20

... assess the distribution of the eruption accurately The patient should first be viewed from a distance of about 1.5–2 m (4–6 ft) so that the general character of the skin and the distribution of lesions ... eruption than is a patient with a similar rash limited to the sun-exposed portions of the face Once the distribution of the lesions has been established, the nature of the primary lesion must be ... distribution of lesions often correlates highly with diagnosis (Fig 52-6) For example, a hospitalized patient with a generalized erythematous exanthem is more likely to have a drug eruption than is a patient...

Ngày tải lên: 06/07/2014, 20:20

... The distribution of some common dermatologic diseases and lesions Figure 52-7 Psoriasis This papulosquamous skin disease is characterized by small and large erythematous papules and plaques with...

Ngày tải lên: 06/07/2014, 20:20