... suggestive of CD without increasing the risk of misclassification Preconditions are • • • • high quality serology including EMA taking quantitative antibody levels into account HLA typing full information ... antibody levels there no urgency to perform biopsies compared to symptomatic patients with the same low levels Conclusions The new guidelines will offer the option of omitting biopsies in selected ... gluten and related prolamines in genetically (mainly HLA) susceptible individuals characterized by a combination of: • gluten dependent clinical manifestations • anti-tissue transglutaminase...
... problems originate early in life with up to 50% ofchildrenandadolescents experiencing low back pain within the course of a year and a third of these will experience recurrent pain [10-12] Even more ... subject to bias) and non-randomized clinical studies were included if they investigated the effect of manual therapy on musculoskeletal disorders inchildren and/ or adolescents Therefore, we excluded ... the titles ofthe case reports and found 35 studies of dislocations Excluding dislocations, we were able to identity 23 studies describing the effect of manual therapy inchildren Eleven of these...
... ofchildrenandadolescents with bipolar disorder In particular, the number of controlled treatment studies of mania inchildrenandadolescents is rapidly increasing, thereby greatly improving ... address these concerns In conclusion, we hope that the information provided in this book will enable clinicians, parents, and other individuals involved inthe treatment ofchildrenandadolescents ... a National Institute of Child Health and Human Development contract examining lithium inthe treatment of pediatric mania and also the principal investigator of a National Institue of Mental Health...
... absence of older adolescentsInthe second study, Geller and Fetner (1989) examined the utility of using the nomogram of Cooper, Bergner, and Simpson (1973) in predicting initial lithium dosing inchildren ... tested the assumption that the lithium levels used in therapeutic drug monitoring in adults are applicable to childrenand adolescents, inthe absence of data to the contrary, this is the dosing ... exercised in translating thein vitro and animal findings to humans Lithium and Neurotransmission Preclinical studies and information from adult human studies have provided information regarding the...
... discontinuation of nimodipine Yingling and colleagues report the use of nimodipine inthe treatment of a pregnant patient with bipolar disorder (Yingling, Utter, Vengail, & Mason, 2002) She was being ... massage, and acupuncture) and energy (biofeedback and magnetic) therapies In addition, there are a variety of mind–body interventions that include prayer, meditation, mental healing, and energy and ... rapid-cycling bipolar disorder were maintained on lithium and other medications Choline bitartrate capsules were added, starting at 2–4 grams of free choline daily and increasing to 3–8 grams as maintenance...
... Carl and his mother attended sessions The therapists pointed out the importance ofthe involvement ofthe whole family Carl’s mother agreed that she would share handouts andthe content ofthe therapy ... learning the components ofthe skill with the aid of a handout (e.g., for active listening: paraphrasing, keeping eye contact), (2) observing the clinician modeling the skill, (3) practicing the ... aware of their “punch–counterpunch” style and would often stop themselves before the therapists intervened The clinicians then emphasized exporting this skill to the home setting, with the help of...
... ofthe SUD However, systematic reporting of SUD was not undertaken, and CD in youths was defined, in part, by the presence of SUD, confounding the role of juvenile CD in predicting later SUD In ... cognitive and neuropsychological functioning in adults (Block, 1996), although the extent of these findings in youths remains unclear Given the increasingly growing concern with neuropsychological and ... hospitalization was necessary, andthe atomoxetine was stopped Within days of atomoxetine discontinuation, the boy’s behavior returned to his baseline functioning Inthe case histories ofchildren with mania,...
... of mania in families of probands with OCD andin families of probands with bipolar disorder Similarly, an increased incidence of obsessional traits has been reported inthe offspring of probands ... to be important in positioning the parents to more effectively assist the child in maintaining stable mood states by enhancing their awareness and understanding ofthe process of dysregulation ... circumstances and/ or points in time) for the parent to intervene using particular skills and desired goals (i.e., increasing or decreasing duration and/ or intensity of emotion) of treatment In this vein,...
... taken inthe context ofthe uncertainty that surrounds the treatment of bipolar depression in youths CONTROVERSY SURROUNDING THE DIAGNOSIS OF BIPOLAR DISORDER INCHILDRENANDADOLESCENTSThe diagnosis ... IA2 isoenzyme Lamotrigine Lamotrigine is becoming increasingly popular inthe treatment of adults with bipolar depression However, the use of lamotrigine inchildrenandadolescents is limited ... significant increase in mood lability DATA FOR TREATING BIPOLAR DEPRESSION INCHILDRENANDADOLESCENTS Treatment of Unipolar Depression inChildrenandAdolescentsIn adults, there are several classes of...
... acts inthe liver to inhibit the production of insulin-like growth factor (IGF-1) binding protein and SHBG, with the latter leading to an increase in free testosterone Therefore, according to ... the theca interna andinthe follicular responses to exogenous follicle-stimulating hormone (FSH; Franks, 1995) Therefore, the definition of PCOS differs inthe United States andin Europe inthe ... lamotrigine monotherapy), they were somewhat higher inthe valproate group On the other hand, total cholesterol and LDL levels were lower inthe valproate group, and there was no difference inthe insulin...
... 398 OTHER ISSUES assignments, and it exercises the important function of ensuring the continuing scientific validity and ethics ofthe investigation for the duration ofthe study DSMBs are in general ... of harm to the patient or other person if the clinician was aware ofthe danger and could have been prevented the harm Inthe landmark case of Tarasoff vs Regents ofthe University of California ... identify the need for systematic research in order to acquire the necessary evidence for efficacy and safety Following the recognition ofthe widespread and increasing off-label use of medications in...
... ratings ofthe patients, the parents andthe physicians at baseline andthe following points in time Except for the first rating by the patients, all alpha values were above 0.80, indicating ... ofthe boys and 39 (47.0%) ofthe girls were diagnosed with the combined subtype The predominantly inattentive subtype was diagnosed in 86 (25.4%) ofthe boys and 38 (45.8%) ofthe girls The ... reflect the healthrelated quality of life inchildrenandadolescents with ADHD [25] However, since the introduction of various long-acting ADHD medications, interest in duration of action of these...
... running" instead of "running" and "never was a problem" instead of "never") to increase comprehensibility The second wave of cognitive interviews was carried out in 30 childrenand parents and ... Families were then approached inthe clinic before seeing their doctor and invited to enroll inthe study After enrolling, childrenand proxies were asked to independently complete the PedsQL™ ... Cardiopathies 6Poverty line is calculated according to total income, and number and age of people inthe household, as per National Institute of Statistics and Census (INDEC) guidelines ical and psychosocial...
... qualitative in nature, for example the clinical opinion gained from the relevant consultants participating inthe project, cognitive interview feedback from thechildrenand adolescents, andthe investigator's ... to a domain if it correlated with a domain, it loaded only on one domain, and it generally made sense to include the item inthe domain [29] The reliability ofthe domain, including the added ... data during the item selection process This included the percentage of 'not applicable' and 'never' responses, a cognitive interview andthe clinical judgment of clinicians and investigators The...
... Determination of Brain Death in Infants andChildren Critical Care Medicine 2011;39:2139–2155 Nakagawa TA, Ashwal SA, Mathur M, Mysore M Guidelines for the Determination of Brain Death in Infants and ... recommendations for the process of diagnosing brain death inchildren When ancillary studies are used, documentation of components from the second clinical examination that can be completed, including a second ... must remain consistent with brain death All aspects ofthe clinical examination, including the apnea test, or ancillary studies must be appropriately documented 4 References Guidelines for the Determination...
... phosphine is a quick and effective tool for the control of stored-product insect pests In view ofthe scheduled phaseout of methyl bromide under the Montreal protocol, the role of phosphine in grain ... of all oils tested The main component of one ofthe oils is pulegone The other is not yet identified and it is called SEM76 (Shaaya and Kostyukovsky, 2006) In our study ofthe mode of action of ... evaluate the toxicity of allyl ITC in grain, we could show that 20 μL·L−1 air (=20 g m−3 ) and exposure time of day were not effective in killing the insects at the bottom ofthe column when the fumigant...
... the profits ofthe firms producing them The increased profit will give the proprietors of these firms the financial ability, andthe motivation, to obtain additional inputs to expand output of ... and to a degree, consider the feelings and costs that they may impose on others We talk in terms ofthe logic ofthe extreme individualist because some people, inand out of business andinand ... both Fred and Harry combined is MB1 ; the marginal cost, MC They can gain by eliminating that dandelion and all others up to Q3 This is the point where the marginal cost curve andthe public...
... you through the background on frame rates and their technical basics, explain some ofthe issues and challenges faced by the industry, outline where things are going and, finally, explain how easy ... or 240 FPS without increasing the number of repeated frames Doing so, removes any hint of flickering, strobing and judder and creates a more compelling and engaging movie-going experience Films ... traditional cinema content, and passes it through the video pipeline ofthe projector, while maintaining or enhancing the visuals that hit the big screen It will handle both cinema and alternative...
... assigned the class ofthe majority ofthe items which reached it during training The trees were grown using recursive partitioning; the splitting criterion was reduction in deviance Using the Gini index ... From the complete set of documents, we constructed three pairs of training and test sets for training the feature classifiers The test sets are mutually disjunct; each of them contains positive and ... overfitting We varied both the number of codebook vectors (10,20,50,90) andthe initialisation procedure: during one set of runs, each class receives the same number of vectors, during the other, the...